Gene AqueK406 (A.queenslandica)

AqueK406

Species: A.queenslandica
Alias: AqueK406
External Links:
Annotation:

Classification

Group: TK
Family: Ryk

Sequence

Name Sequence Type Origin Length Description Download
AqueK406.AA Protein None 420 None Fasta, JSON
AqueK406.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of AqueK406.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK406.AA Ryk 127-409 36 1.6e-84 267.18 In-house 1-292 (292) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-292/292
Sequence Identity: 36% (115 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVE------------GAIPVIIKTVKDNTPDIVVKSLLEGGAATRGVI-HRHLLPLIGAH--------ASDLEQP
||    ..|| ||  | | . | .|||.                | .|||||.   . |. .|  .   .|.  |...||. ..          .| . |
IQYSCLVQEGTFGRIYHGIW-NQVDDVNNGDVDDEEDTFCDCQDVFVKTVKDHASQMQVHCMLQESCLLYGISPHQNILPVLHVCSFGRFDRPIEDHDPP

MLLYPKSS-FGTLKTLLLKTREGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHEN---LHVKIGDRGLSWDFYPEDY
. .||  . .| ||  | . |    .  .....   . ||||.||    |.. || || ... ||||.| || .| |    | ||| |  || |  | ||
FVCYPHMNNWGNLKQFLQDCR----H-DKPKCH---QAISTHQLVHMAIQITMGMMHLHKHRIVHKDIATRNCVIDEQNGRLQVKICDSALSRDLFPMDY

NTI---EERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSD
.     | |          |||||. | |  | ||. |||||||| .|| || |..||... |. | .||  | ||.|| |||| ||  |  ||.. | .
HCLGDNENR----------PVKWMSLESLQHKHYSHASDVWSFGVTMWELMTLGQMPYMEIDPFEMYHYLKDGYRLQQPFNCPDELFTVMACCWHCMPEE

RPRFSHLTVRL
|| |. |   |
RPTFQQLVQCL
Kinase AqueK406.AA TyrKc 127-409 29 4.5e-72 246.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-280/280
Sequence Identity: 29% (93 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPDIVVKSLLEGGAATRGV--IHRHLLPLIGAHASDL------EQPMLLYPKSSFGTLK
|... || || ||. |.| ..         |.| .|..|...    .. ...     . .   | ... |.|.  ..       |..|..    . | ||
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

TLLLKTREGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPE-------DYNTIEERGGGG
  | |.|.                ... ||. .. |.|.|| .| .|. .| |||.||. ..||..|||.| ||| | | .       || .  |..|| 
DYLRKHRPK---------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGG-

DETIA-YPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYED-----VLPENMLNYLTTGHRLPQPKN--------CPDDLFSLMGWCWALTPS
    .  |..||| |.. ...... ||||||||..|||.|.|..||..     . .. ...|. .|.|.|||.|        |||.....| .||.  |.
---KTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

DRPRFSHLTVRL
|||.|| .  ..
DRPTFSEIHECF
Kinase AqueK406.AA Pkinase_Tyr 127-409 34 1.2e-71 243.27 Pfam 1-270 (270) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-270/270
Sequence Identity: 34% (99 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPDIV--VKSLLEGGAATRGVI--HRHLLPLIGAHASDLEQ--PMLLYPKSSFGTLKTL
|.|. || || ||. |.|...   |. .. ||| .|..|... .     .....  |..   .  | ... |.|.  .. |.  ...  .    | |.. 
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LLKTREGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVK
| | |          ...|   ....||. .. |.|.|| .| .|. .| |||.||. ..||..|||.| ||. | |..||  .  ||||       |.|
LRKHR----------EDKQP--LTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKL-----PIK

WMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTP-YEDVLPENMLNYL-TTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRL
||| |......... ||||||||..|||.|.|..| |... .| ...|.   |.|.|.|.||||.. .||  ||.  |.|||.|| .  .|
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK406.AA TK 127-409 19 8e-70 233.01 In-house 1-486 (486) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-486/486
Sequence Identity: 19% (95 aa)

IQFNAKLMEGVFG---VMYEGYLTNAED-------------------DVEGAIPVIIKTVKDNTPDIVVKSLL--------------EGGAATRGVI---
|..  || || ||   . |.| . .  .                    ..| .|| .|..|. ...     ..              |  ..        
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRHLLPLIG-AHASDL----------EQPMLLYPKSSFGT----LKTLLLKTREGGGI---MLPGNNSGQCTY--------------------------
 | ... |.|  . ..           | .|..    . |     |.. | | |...       ........ .                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ISTHDLVFISEQVARGMYHLTRK------GQVHKDLACRNIYIHENLH-----------VKIGDRG---
                               ...|.|. .. |.|.|| .| .|      . || |||.||. ..||..           .||.| |   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSWDFYP-EDYNTIEERGG-----------GGDETIA-----YPVKWMAAEVLS---------DKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVL
     |. | |. .|| . ...|.           . |.. .      |..||| |.|          ...... ||||||||..|||.|.|..||   .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

P----------ENMLNYLTTG--------------HRLPQPKNCP--------------DDLFSLMGWCWALTPSDRPRFSHLTVRL
.          . ...||..|              .|.|||..||              .... ||  ||.. |.|||.|| |  .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK406.AA TK-Unique 127-409 27 1.6e-59 203.87 In-house 1-294 (294) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-294/294
Sequence Identity: 27% (84 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPDIVVKSLLEGGAATRGVI-HRHLLPLIGAHASDLEQPMLLYPKSSFGTLKTLLLKTR
. .. .. || ||  . | ...   . .  . |..|..|||  |  .. .|   .  . .  | ... ..|.  .. |..|....  . |.| ..| ..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

EG--GG-------IMLPGNNSGQCTY-ISTHDLVFISEQVARGMYHLTR--KGQVHKDLACRNIYIHENLHVKIGDRGLSWDFY-PEDYNTIEERGGGGD
 .  ..       . .. ..... |. || .||. .  |.|.|| .| .  |. ||.||. ||. . |.. .||.| |.. | | ...|......|    
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRI--

ETIAYPVKWMAAEVLS--DKRY-SSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNC-PDDLFSLMGWCWALTPSDRPRFSHLTVR
     |..||| |.|.  .. | .. ||||||||..|||.| |..|| .. ...... .. |.|.|||..| ......||  || . |..|| |. .. |
-----PIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHR

L
|
L
Kinase AqueK406.AA Met 254-403 42 2.3e-55 179.86 In-house 112-271 (271) Show / Hide 
Range on Protein: 254-403
Range on HMM: 112-271/271
Sequence Identity: 42% (70 aa)

QVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDF-YPEDYNTIEERGGGGDETI--AYPVKWMAAEVLS--------DKR-YSSSSDVWSF
|||.||  .  .  || ||||||  . | . ||..| ||. |  |   |   .      ..|     |||||| | |         . | ... ||||||
QVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQM------HHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSF

GVVLWEIMTRGKTPYEDVLP-ENMLNYLTTG--HRLPQPKNCPDDLF-SLMGWCWALTPSDRPRFS
|||.|| |||| .|| .| .    . .| .|   |||||  ||| |   .|  ||  .| ||| ||
GVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS
Kinase AqueK406.AA UTK 127-409 25 2.2e-53 181.01 In-house 1-296 (296) Show / Hide 
Range on Protein: 127-409
Range on HMM: 1-296/296
Sequence Identity: 25% (79 aa)

IQFNAKLMEGVFGVMYEGYLTNAE---DDVEGAIPVII---KTVKDNT--P-------DIVVKSLLEGGAATRGVIHRHLLPLIGAHASDLEQPMLLYPK
.|. ..| .| ||. ... .|..     ..  |..|     .. .. .  |       .... . ..         |...| |.| . .. |..|...  
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFH--------WHPNVLRLVGVCTQE-EPWMIVTEY

SSFGTLKTLLLKTREGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHEN-------LHVKIGDRG---LSWDFYPEDY
 . | | ..| . |.  .        .. .. . |...  . ..|||| .| ..| || |||.||...|..       . .||.| |   .| . . .  
MENGDLRSYLRRHRPTPP--------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH-

NTIEERGGGGDETIA-----YPVKWMAAEVLSDK-RYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTG--HRLPQPKNCPDDLFSLMGWCWA
 .   | .. ..  |      |..||| |.| .  |....|||||||||.|||.|.|..||..   .. .  .. |  .|.|.|. ||.... ||  ||.
FSN--RYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWH

LTPSDRPRFSHLTVRL
 .|..||.|  |. ..
YDPQERPDFEDLVQQM
Kinase AqueK406.AA Axl 127-407 37 1e-51 178.14 In-house 1-267 (267) Show / Hide 
Range on Protein: 127-407
Range on HMM: 1-267/267
Sequence Identity: 37% (107 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVK-DNTPDIVVKSLLEGGAATRGVIHRHLLPLIGA--HASD---LEQPMLLYPKSSFGTLKTL
.     | || || . || | . ||     . | .|..| |.     .   |   |  .   | . . |||   ..|.   . .|| . |   .| | | 
FVLGKMLGEGEFGSVMEGQL-KQEDGS--FVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHTF

LLKTREGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVK
||  | |           |  |. .  ||     .| ||  |  .  .|.||| ||  ..|.. | . | |||   |  ||     | |        |||
LLYSRLG----------DQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYY----RQG---CIAKMPVK

WMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTV
|.| | | |. | | ||||.||| .|||||||.|||  |  . | .||  |||| ||..| |.|. ||  || . | ||| || |  
WIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase AqueK406.AA EGFR 243-410 36 4.2e-49 161.07 In-house 98-258 (258) Show / Hide 
Range on Protein: 243-410
Range on HMM: 98-258/258
Sequence Identity: 36% (62 aa)

ISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFG
|  ..|.  . |.|.||. |  .  || ||| ||. .    |||| | ||. .. . | . ..  ||        |.|||| |... ..| . |||||.|
IGSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLA-KLLEHDEKEYHAQGG------KMPIKWMALECIHHRCYTHQSDVWSYG

VVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRLK
| .||.|| |. ||. .  ..  . |  | |||||..|  |.. .|  || . .  ||.|  |. ..|
VTCWELMTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDEDMRPTFKELYEEFK
Kinase AqueK406.AA Frk 248-413 36 1e-43 149.2 In-house 100-260 (260) Show / Hide 
Range on Protein: 248-413
Range on HMM: 100-260/260
Sequence Identity: 36% (61 aa)

LVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWE
|| .. ||| ||  |  .  .|.||| ||. . |.. .|| | ||   .  .. .  | | |     . .|.|| | |    ....  |||||||..| |
LVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHG-----ARFPIKWTAPEAANYNKFTIKSDVWSFGILLTE

IMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRLKEFY
|.| |. ||  .   ..|. .  | |.||| |||  |...|  ||   |  || |  |  .|....
IITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK406.AA InsR 254-411 40 6.6e-41 135.07 In-house 127-278 (278) Show / Hide 
Range on Protein: 254-411
Range on HMM: 127-278/278
Sequence Identity: 40% (65 aa)

QVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGK
... ||  |  |  || ||||||  . . . ||||| |.  | |  ||   . .|         || ||| | | |  ....||||||||||||. | | 
EICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKG-------MLPVRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGE

TPYEDVLPENMLNYL-TTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRLKE
 ||     |  |.|    |  | .| |||. .. ||  ||.  |..|| | ..   |..
QPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase AqueK406.AA FGFR 318-409 46 1.1e-39 132.86 In-house 201-293 (293) Show / Hide 
Range on Protein: 318-409
Range on HMM: 201-293/293
Sequence Identity: 46% (43 aa)

PVKWMAAEVLSDKRYSSSSDVWSFGVVLWEIMTRGKTPYEDVL-PENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTVRL
|.|||| | | |. | . |||||.|| |||||| | .||  ..  | .  || .|||.  |.||. ... .|  ||   |..|| |  |   |
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase AqueK406.AA Pkinase 241-400 21 2.1e-16 59.07 Pfam 101-282 (293) Show / Hide 
Range on Protein: 241-400
Range on HMM: 101-282/293
Sequence Identity: 21% (41 aa)

TYI--STHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHV----KIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAAEVLS-DKRYS
. .  | ... |.  |..||.... ..| .| ||   || |..| |.    ||.| ||.  |.        .  ..   |..    .|| ||.  .. |.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

SSSDVWSFGVVLWEIMTRGKTPYEDV-------LPENMLNYLTTGHRLPQPKNCP-------------------DDLFSLMGWCWALTPSDRP
...|.||.|..|.| .. |..|. .          . . . . .  . . |. |.                   ... ... ||... |..||
PKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase AqueK406.AA S_TKc 127-413 17 2.5e-15 47.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 127-413
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPDIVVKSLLEGGAATRGVIHRHLLPLIGAHASDLEQPMLLYPKSSF--GTLKTLLLKT
 ..  |. .| ||. | .. ..          | || .|        . . |     .   | ..  |...  .  .   .     .   |.|.... | 
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKR

REGGGIMLPGNNSGQCTYISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDYNTIEERGGGGDETIAYPVKWMAA
. .|.          . ...  .  |.  |..... .. ..| .| ||   || . |  |.||.| ||.  .                 |.     .|| 
GRHGL----------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAP

EVLSDKRYSS-SSDVWSFGVVLWEIMTRGKTPYEDVLPENMLNYLTTGHRLPQPKNCPDDLFSLMGWCWALTPSDRPRFSHLTV-----RLKEFY
|||    |.  ..|.||.|..|.| .. |..|..   .. |.. .            .... ...  |.   |..||    .       .. .. 
EVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK406.AA FGFR 243-301 40 4.8e-09 26.9 In-house 133-191 (293) Show / Hide 
Range on Protein: 243-301
Range on HMM: 133-191/293
Sequence Identity: 40% (24 aa)

ISTHDLVFISEQVARGMYHLTRKGQVHKDLACRNIYIHENLHVKIGDRGLSWDFYPEDY
..  ||| .  ||||||  |  .  .| ||| ||. . ..   || | ||. |    ||
LTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDY
Kinase AqueK406.AA InsR 127-167 33 1e-06 18.15 In-house 1-42 (278) Show / Hide 
Range on Protein: 127-167
Range on HMM: 1-42/278
Sequence Identity: 33% (14 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAI-PVIIKTVKDN
|  .... .| ||  ||| . . ..| | .  .. ||||..|
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNEN
Kinase AqueK406.AA EGFR 127-196 28 0.000311 9.76 In-house 1-68 (258) Show / Hide 
Range on Protein: 127-196
Range on HMM: 1-68/258
Sequence Identity: 28% (20 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPDIVVKSLLEGGAATRGVIHRHLLPLIG
..   .|  |.||  | |      . |   ||| || ....|     . .|.   .  .| | ||. |.|
LKKVKVLGSGAFGTVYKGIWIPEGENVK--IPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLG
Kinase AqueK406.AA Frk 127-170 36 0.078886 1.71 In-house 1-37 (260) Show / Hide 
Range on Protein: 127-170
Range on HMM: 1-37/260
Sequence Identity: 36% (16 aa)

IQFNAKLMEGVFGVMYEGYLTNAEDDVEGAIPVIIKTVKDNTPD
||.  .|  | || ..||   |       ..|| .||.|  | |
IQLIRRLGSGQFGEVWEGLWNN-------TTPVAVKTLKPGTMD