Gene AqueK417 (A.queenslandica)

AqueK417

Species: A.queenslandica
Alias: AqueK417
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK417.AA Protein None 180 None Fasta, JSON
AqueK417.kin_dom Protein Kinase Domain None 171 None Fasta, JSON

Protein domain

Protein domains of AqueK417.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK417.AA Src 4-175 44 7.3e-73 246.88 In-house 80-255 (255) Show / Hide 
Range on Protein: 4-175
Range on HMM: 80-255/255
Sequence Identity: 44% (78 aa)

NLRNYLN-RPPTQ-AEVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLN-GKKYWIVEKGTRVAIRWTAPEAYTLKRLSI
.|  ||  .. ..  .. .|.|.| || .|| ||... ||| ||.| |.| |..| .|.| | ||. .  ..     ..| .. |.|||||| .  | .|
SLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTI

KSDVWSFGILLWELATKGKEPYPGMTNAQVLESVSKGYHMPIPRNCPEPFEL-LMMNCWKQNEDQRPTFIHIFNIL
|||||||||||.|. |.|. |||||||..||. |..||.|| |.|||. .   .|. ||..  .|||||  ... |
KSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK417.AA SFK-Src 20-168 48 6.7e-72 212.18 In-house 97-248 (259) Show / Hide 
Range on Protein: 20-168
Range on HMM: 97-248/259
Sequence Identity: 48% (73 aa)

KLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKY-WIVEKGTRVAIRWTAPEAYTLKRLSIKSDVWSFGILLWELATKG
.||| | ||  || || .| ..| || | |.| || |..|.. | ..  |  .   .  ..| .  |.|||||| .  | ||||||||||||. |. | |
QLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYG

KEPYPGMTNAQVLESVSK--GYHMPIPRNCPEPFELLMMNCWKQNEDQRPTF
  |||||||. ||  | .  || || | |||. .  .|..||... | ||||
RIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK417.AA SrcA 20-175 51 7.6e-65 203.66 In-house 96-250 (250) Show / Hide 
Range on Protein: 20-175
Range on HMM: 96-250/250
Sequence Identity: 51% (81 aa)

KLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSIKSDVWSFGILLWELATKGK
.|||.| || .|| |.    ||| |||| ||| |..   ||| | ||  ..   |   ..|..  |.||||||    |  |||||||||||| || |||.
QLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR

EPYPGMTNAQVLESVSKGYHMPIPRNCPEPFELLMMNCWKQNEDQRPTFIHIFNIL
 ||||| |  ||| | .||||| |..|||    ||. ||... . ||||  .   |
VPYPGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK417.AA Pkinase_Tyr 4-175 38 1.8e-63 215.57 Pfam 93-270 (270) Show / Hide 
Range on Protein: 4-175
Range on HMM: 93-270/270
Sequence Identity: 38% (69 aa)

NLRNYLNRP---PTQAEVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKYW-IVEKGTRVAIRWTAPEAYTLKRLS
.|..|| ..   . .  .  |.....|. .|| || .. .|| ||.| |.|... |.|||. | ||  .  . |   . .|... |.|.|||.   .. .
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT

IKSDVWSFGILLWELATKGKEP-YPGMTNAQVLESV-SKGYHMPIPRNCPEPFELLMMNCWKQNEDQRPTFIHIFNIL
.||||||||.|.||. | |..| ||||.|..|.| .  .|| ||.|.|||..   ||. ||... ..||||  | ..|
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK417.AA Frk 1-168 48 2.4e-61 210.11 In-house 76-249 (260) Show / Hide 
Range on Protein: 1-168
Range on HMM: 76-249/260
Sequence Identity: 48% (84 aa)

MHQN-LRNYLN---RPPTQAEVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKY--WIVEKGTRVAIRWTAPEAYT
|... | .||    .   | .. .|||.| ||  || || .| ||| || | |.|.|.|| .||| | ||  |   .   .    | |. |.||||||  
MRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAAN

LKRLSIKSDVWSFGILLWELATKGKEPYPGMTNAQVLESVSKGYHMPIPRNCPEPFELLMMNCWKQNEDQRPTF
 .. .|||||||||||| |. | |. ||||||||.||. |..|| || | |||. .  .|..||... ..||||
YNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTF
Kinase AqueK417.AA TK 4-175 21 1.5e-59 197.97 In-house 141-486 (486) Show / Hide 
Range on Protein: 4-175
Range on HMM: 141-486/486
Sequence Identity: 21% (73 aa)

N----LRNYLN--RPPTQAE-------------------------------------------------------------------------VVKLVDI
.    ||.||   ||..| |                                                                         .  |. .
DMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-M

AIQVTDGMIYLGEQ------DYIHCDLRAENILLGDHNT-----------VKIANFH--------LAQHL-NGKKYWIVE--------------------
. |. .|| || ..       ..| || | |.|.|..|.           .||| |         ||  . ... |. ..                    
CWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYY

---KGTRVAIRWTAPEAYT---------LKRLSIKSDVWSFGILLWELATKGKEPYPG-MTN---------AQVLESVSKG--------------YHMPI
   .|... |||.|||. .          .. ..||||||||.|.||. | |.|||.| |.|         ..|.| . .|              . || 
RQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQ

PRNCP--------------EPFELLMMNCWKQNEDQRPTFIHIFNIL
| .||              | ...||. ||. . ..||||  . . |
PPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK417.AA SrcB 15-176 46 8.1e-57 190.7 In-house 91-251 (251) Show / Hide 
Range on Protein: 15-176
Range on HMM: 91-251/251
Sequence Identity: 46% (75 aa)

QAEVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSIKSDVWSFGILLWEL
. .. ||.|.. |...|| |. .. ||| |||| |||  .    ||| | ||  ..   |   | | .  |.||||||       |||||||||||| |.
KLSLPKLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTARE-GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEI

ATKGKEPYPGMTNAQVLESVSKGYHMPIPRNCPEPFELLMMNCWKQNEDQRPTFIHIFNILY
 | |. |||||||..|......|| || | ||||    .|| |||.  ..|||| ..  .| 
VTYGRIPYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK417.AA Src-Echino1 2-175 42 5.6e-55 188.96 In-house 78-252 (252) Show / Hide 
Range on Protein: 2-175
Range on HMM: 78-252/252
Sequence Identity: 42% (74 aa)

HQNLRNYLNRPPTQ-AEVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSI
. ||..|| |  ..   . .|.|.  ..  || |||.....| || | |.|.|. | .|||.| ||. ..   | . ..| .. |.||||||    |  |
NGNLQDYLKRGKCKHVKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVY-CGKQGAKLPIKWTAPEAALYGRFTI

KSDVWSFGILLWELATKGKEPYPGMTNAQVLESVSKGYHMPIPRNCPEPFELL-MMNCWKQNEDQRPTFIHIFNIL
||||||||||. |. | |. |||||.| .||. | .|| || . .||.    . || || ..  ||||| .. . .
KSDVWSFGILMTEMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK417.AA SRM 4-176 43 1.7e-54 180.64 In-house 81-253 (253) Show / Hide 
Range on Protein: 4-176
Range on HMM: 81-253/253
Sequence Identity: 43% (76 aa)

NLRNYLNRPPTQA-EVVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSIKS
||  ||  .  .|  . .|.|.| ||  || || || ||| || | |.| || |. |.. | ||  .    |     . .. ..||||||      |.||
NLQQYLRDSDEKALPIPHLLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIY-SPSHDHNIPYKWTAPEAANYRHYSQKS

DVWSFGILLWELATKGKEPYPGMTNAQVLESVSKGYHMPIPRNCPEPFELLMMNCWKQNEDQRPTFIHIFNILY
|||||||||.|. |.|  |||||||   .  ...|| || |  ||     ||. ||..  .|||.|      | 
DVWSFGILLHEMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK417.AA UTK 4-168 35 3.1e-54 183.93 In-house 96-289 (296) Show / Hide 
Range on Protein: 4-168
Range on HMM: 96-289/296
Sequence Identity: 35% (69 aa)

NLRNYLNRPPTQAE-------VVKLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDH-------NTVKIANFH---LAQHLN---------GKKYWIV
.||.|| | . ...         .... | .. .|| || .. ..|.|| | |.|...|       ...|||.|    ..  .|         .  |   
DLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA

EKGTRVAIRWTAPEAYTLK-RLSIKSDVWSFGILLWELATKGKEPYPGMTNAQVLESVSKG--YHMPIPRNCPEPFELLMMNCWKQNEDQRPTF
   .|..|||.||||.|   | ..||||||||...||. | |. |||||.|.||...|..|  |.|| |. ||.|   ||. ||... . ||.|
QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDF
Kinase AqueK417.AA Src-Unclassified 22-175 44 7.3e-54 183.05 In-house 122-284 (284) Show / Hide 
Range on Protein: 22-175
Range on HMM: 122-284/284
Sequence Identity: 44% (72 aa)

VDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHN-----TVKIANFHLA-QHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSIKSDVWSFGILLWELA
|||| ||  || || .  |.| || | |.| |. |      ||.. | ||   | .    .  .| .  . |.|||. .    ||||||||.||||||..
VDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIM

TKGKEPYPGMTNAQVLESVSKGYHMPIP--RNCPEP-FELLMMNCWKQNEDQRPTFIHIFNIL
|||. ||||| |  ||| |. || || |  . ||.   | .|  || .  ..||||   .. .
TKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK417.AA TyrKc 1-175 25 5.5e-22 80.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 1-175
Range on HMM: 1-280/280
Sequence Identity: 25% (70 aa)

M-------------------------------------------------------------HQ--------------------NLRNYLNRPPTQAEVV
                                                              .|                    .|..|| ..  .  . 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

KLVDIAIQVTDGMIYLGEQDYIHCDLRAENILLGDHNTVKIANFHLAQHLNGK-------KYWIV--EKGTR--VAIRWTAPEAYTLKRLSIKSDVWSFG
.|.....|. .|| || .. .|| || | |.|.|. .||||. | |.  .  .       .|  .  .||..  . |||.|||.   .. ..||||||||
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFG

ILLWELATKGKEPYPG-----MTNAQVLESVSKGYHMPIPRN--------CPEPFELLMMNCWKQNEDQRPTFIHIFNIL
...||. | |..||||     |.|..|.| | .|| ||.| |        ||.    .|  ||. . ..||||  |  ..
VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK417.AA Pkinase 41-177 21 9.6e-13 46.14 Pfam 130-293 (293) Show / Hide 
Range on Protein: 41-177
Range on HMM: 130-293/293
Sequence Identity: 21% (36 aa)

IHCDLRAENILLGDHNTV----KIANFHLAQHLNGKKYWIVEKGTRVA-IRWTAPEAYT-LKRLSIKSDVWSFGILLWELATKGKEPYPGM----TNAQV
||.||  ||||. .....    ||. | || ...      .   |..  ... |||     .  . |.|.||.|..|.|... |. |.||     . .  
IHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQ

LESVSKGYHMPIPRNCP-----------------------EPFELLMMNCWKQNEDQRPTFIHIFNILYL
.. . .  . |.....|                       |..  .. .|....  .|||. .|..  ..
MQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK417.AA S_TKc 1-177 15 4.4e-10 -29.06 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-177
Range on HMM: 19-231/231
Sequence Identity: 15% (37 aa)

MH--------------------------------------------------Q---NLRNYLNRPPTQ-----AEVVKLVDIAIQVTDGMIYLGEQDYIH
 |                                                  .   .|. |. . ...             .. |. ... |. ..  ||
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIH

CDLRAENILLGDHNTVKIANFHLAQHLNGKKYWIVEKGTRVAIRWTAPEAYTLKRLSI-KSDVWSFGILLWELATKGKEPYPGMTNAQVLESVSKGYHMP
.||  ||||| .  ..||. | || .|         .   .   . |||       .  |.|.||.|..|.|... |. |.|  . ..... .       
RDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG------

IPRNCPEPFELLMMNCWKQNEDQRPTFIHIFN-------ILYL
     ....  ....|.. . ..|||   ...         ..
-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF