Gene AqueK425 (A.queenslandica)

AqueK425

Species: A.queenslandica
Alias: AqueK425
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK425.AA Protein None 973 None Fasta, JSON
AqueK425.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK425.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK425.AA SH2 599-670 43 4.7e-26 78.32 Pfam 6-81 (81) Show / Hide 
Range on Protein: 599-670
Range on HMM: 6-81/81
Sequence Identity: 43% (33 aa)

VSRDKAEKKMSQADTQAGTFLIRDSESKPGQHALSLNDGF---TIRNYRIYIEDNK-YYMNPRVKFDSLNDLVHHY
.|| .||.   .   . ||||.|.|||.||. .||. |.     .. |||  .||. ||.  |.||.||..||.||
ISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK425.AA SH2 593-676 39 8.1e-25 89.69 SMART 1-87 (87) Show / Hide 
Range on Protein: 593-676
Range on HMM: 1-87/87
Sequence Identity: 39% (35 aa)

YTYYH-MVSRDKAEKKMSQADTQAGTFLIRDSESKPGQHALSLNDGFTIRNYRIYIED-NKYYMNP--RVKFDSLNDLVHHYMMKANG
. .|| ..||..||..  .   . |.||.|||||.||. .||. ..  ...|||  .| .|||     |.||.|| .||.||.  . |
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK425.AA SFK-Src 709-960 41 3.4e-87 258.38 In-house 1-259 (259) Show / Hide 
Range on Protein: 709-960
Range on HMM: 1-259/259
Sequence Identity: 41% (107 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPI-NGNLKQYLIT---NNPTPAELVD
|   | |  | ||..||| | ..  | .||     . .| | .|   . || |.| | || ||    | ||||| . .| |  ||        .   |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKY-WTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPY
 | ||  || || .| ..| || | |.| || |. |.. | ..  |  .   .| ..| |  |.|||||    |. ||||||||||||. |. | |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMTDKEVKEAVSK--GYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQFDAPV
|||| .||   | .  || || |..||. . |. .|| . .  ||| | .   | .   
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK425.AA Src 709-956 39 1.7e-85 290.38 In-house 1-255 (255) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-255/255
Sequence Identity: 39% (101 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITE-PINGNLKQYLI----TNNPTPAELV
|.  . |  |.||| |.| |.|.  | .||  . .  .| | .|.  . || |.....|| || .  |.||.||   .|.| .||     . .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLN--GNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKE
|.| || ||| ||... ||| ||.| |.| |..|  |.| | ||. .    . | . ..| |. |.|||||    .. .||||||||||||.|. |.|. 
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTDKEVKEAVSKGYHMPIPQGCPEPFIK-LIIDCGKYNDYDRPNFKNIFDQF
|||||| .|| ..|..||.|| |..||. . . ..  | .    .|| |. ... .
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK425.AA Abl 709-956 39 5.5e-75 249.5 In-house 1-252 (252) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-252/252
Sequence Identity: 39% (101 aa)

ITSFKCLHVGKFGEIWKGDWKGKG-TVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPI-NGNLKQYLITNNPT---PAELV
|.  . |  |..||...| ||  . || .||    ..  . |..|   .....|.|.. | |||    ||||||| . .||| .||  .. .   .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPY
 .| |.. || || ....|| || | | |.|.|.  |.| | ||  .... | | . | |  |.|||||. | |. |.||||| ||.||||.|| |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PGMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQF
||.  ..| . . ||| |  |.|||.   .|.  | ...  ||| ||.|  ..
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK425.AA SrcA 709-956 44 7.2e-75 235.9 In-house 1-250 (250) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-250/250
Sequence Identity: 44% (112 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPIN-GNLKQYLITNNPTP---AELVD
|.  . |  | |||.| | | |.  | |||     .  |.|.||   ..||.|. .. || |  |  | ||.|| .. | |  .|  ..       .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPYP
.| || ||| |.    ||| |||| ||| |..   ||| | ||  .. | | | ..|.|  |.|||||        |||||||||||| || |||. |||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQF
|| ..|| | | .||||| ||.|||    |.. | . .  .|| |  .    
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK425.AA TK 709-956 19 3.2e-74 248.03 In-house 1-486 (486) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-486/486
Sequence Identity: 19% (97 aa)

ITSFKCLHVGKFG---EIWKGDWKGKG--------------------------TVTIKTNIATNITQET------------------FIEEIIKLQ--KL
||  | |  | ||   |..|| |.|..                          .| .|.  ... ....                  . ||. ...  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHQNIISLYGVCIES------------YPFYIITEPIN-GN----LKQYLITN-----------------------------------------------
||.||..||||| ..             |..|..|  . |.    |..|| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NPTPAELVDIAIQVTEGMIYLGEQ------DYIHCDLRAINILLGDHNT-----------FKIANFH---
                              ..|...|. .. |. .|| || ..       ..| || | |.|.|..|.            ||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHL-NGNKYWTIE-----------------------KGTKLAIRWTAPEGYA---------LNQLSIKSDVWSFGILLWELATKGKEPYPG-M
     ||  . ..  |.. .                       .|.|| |||.|||  .          .  ..||||||||.|.||. | |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------KEVKEAVSKG--------------YHMPIPQGCPE-------------PFIKL-IIDCGKYNDYDRPNFKNIFDQF
..         .|| | . .|              . || |..||.             ... . . .| .|.  |||.|. . .|.
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK425.AA Pkinase_Tyr 718-956 37 1.4e-72 246.45 Pfam 10-270 (270) Show / Hide 
Range on Protein: 718-956
Range on HMM: 10-270/270
Sequence Identity: 37% (99 aa)

GKFGEIWKGDWK-----GKGTVTIKTN--IATNIT--QETFIEEIIKLQKL-HHQNIISLYGVCI-ESYP--FYIITEPING-NLKQYLITN-----NPT
| |||..|| ||     .| .| .|.    |.     .| |..|.  . .| ||.||..|||||. .. |   ||..|   . .|. || ..     ..|
GAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLT

PAELVDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHL-NGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELAT
. .|.....|. .|| || .. .|| ||.| |.|... |. ||. | ||  . |   | .  .|.|| |.|.|||  . .  ..||||||||.|.||. |
MKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT

KGKEP-YPGMTDKEVKEAV-SKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQF
 |..| ||||.. ||.|..  .|| ||.|..||..  .|. .| .|.  ||| |. |  |.
YGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK425.AA Frk 709-960 39 3.8e-71 242.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 709-960
Range on HMM: 1-260/260
Sequence Identity: 39% (103 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPINGN-LKQYLI-----TNNPTPAEL
|   . |  |.|||.| | |  .  | .||  .  .  . |. |   ..|| |  .|.|| ||    | ||||| .  . |..||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKY--WTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGK
||.| ||  || || .| ||| || | |.|.|.|| .||| | ||  |  ..   .    | .. |.|||||    |. .|||||||||||| |. | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYPGMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQFDAPV
 ||||||..|| . |..|| || | .||. . .....| . .   || |  .  ...   
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK425.AA Src-Echino1 709-956 37 2.1e-66 226.95 In-house 1-252 (252) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-252/252
Sequence Identity: 37% (96 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPI-NGNLKQYLITNNPT---PAELVD
    | .  |..||.||| |.|   | .||     ...  |. |   ..|. |..|. .| || .. | ||.|| . ||||..||  ..      ..|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPYP
.  ..  || |||.....| || | |.|.|. |  |||.| ||. .. . | . . | || |.|||||     .  |||||||||||. |. | |. |||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTDKEVKEAVSKGYHMPIPQGCPEPFIKL-IIDCGKYNDYDRPNFKNIFDQF
||...|| . | .|| || .. ||.   .. .. |   .   || |. . | |
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK425.AA TyrKc 709-956 35 2.2e-66 227.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-280/280
Sequence Identity: 35% (101 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKL--HHQNIISLYGVCIES-------YPFYIITEPI-NGNLKQYLITNN--
||  | |  | |||..|| ||   .| .|.  .    .| |..|.  . ||  ||.||. |||||...        | .|..|   .|.||.||  .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PTPAELVDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGN-------KYWTI--EKGTK--LAIRWTAPEGYALNQLSIKSDV
 ....|.....|. .|| || .. .|| || | |.|.|. .| ||. | |.  .          .| .   .||.|  | |||.|||    .  ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGKEPYPG-----MTDKEVKEAVSKGYHMPIPQG--------CPEPFIKLIIDCGKYNDYDRPNFKNIFDQF
||||...||. | |..||||     |...|| | | .|| ||.|.         ||.   ... .| ...  |||.|..| ..|
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK425.AA SrcB 709-957 39 1.7e-65 220.48 In-house 1-251 (251) Show / Hide 
Range on Protein: 709-957
Range on HMM: 1-251/251
Sequence Identity: 39% (100 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPI-NGNLKQYLITNNPTPAE---LVD
.   | |  |.|||.| | ....  | .||     .  | |..|   ...| |. .. || |     | ||||| . .| |  .| |.. .  .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPYP
.. |..||| |. .. ||| |||| |||  .    ||| | ||  .. | | |   | |  |.|||||        |||||||||||| |. | |. |||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQFD
|||  || .....|| || |. |||   .... | |    .|| |  .    |
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK425.AA SRM 710-957 42 3.1e-65 217.1 In-house 2-253 (253) Show / Hide 
Range on Protein: 710-957
Range on HMM: 2-253/253
Sequence Identity: 42% (107 aa)

TSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIATN-ITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPIN-GNLKQYLITNNPTP---AELVD
|  . |  | |||.| | |||.  | ||     | . |...  ||  . || |. ||.|. ||    | |||||    ||| ||| . .       .|.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

IAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSIKSDVWSFGILLWELATKGKEPYP
.| || ||| || || ||| || | |.| || |. |.. | ||  .    |     . .  ..|||||       |.|||||||||||.|. |.|  |||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIY-SPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFDQFD
|||  |    ...|| || |  ||    || ..| .    .|| ||    .  
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase AqueK425.AA Src-Unclassified 709-929 38 3.7e-62 211.92 In-house 1-256 (284) Show / Hide 
Range on Protein: 709-929
Range on HMM: 1-256/284
Sequence Identity: 38% (98 aa)

ITSFKCLHVGKFGEIWKGDWKGKGTVTIKTNIAT---NITQETFI--------EEIIKLQKLHHQNIISLYGVCIESYPFYIITE-PINGNLKQYLITNN
.   . |  | |||.|.| |.||  | .||  .        | |         .|   . |. |||.. ||.|| .  |.|||||  ||| | |.| .  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

---PTPAEL------------VDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHN-----TFKIANFHLA-QHLNGNKYWTIEKGTKLAIRWTAPEGYA
   .   ..            |||| ||  || || .  |.| || | |.| |. |       |.. | ||   | .       .| .. . |.|||   
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

LNQLSIKSDVWSFGILLWELATKGKEPYPGMTDKEVKEAVSKGYHMPIP--QGCPE
    ||||||||.||||||..|||. |||||  .|| | |. || || |  ..||.
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPD
Kinase AqueK425.AA S_TKc 709-961 22 2.4e-20 74.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 709-961
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

ITSFKCLHVGKFGEIWKGDWKG-KGTVTIKTNIATNITQETFIEEIIKLQKLHHQNIISLYGVCIESYPFYIITEPING---NLKQYLITNNP-------
 .  . .  | ||. .|. .|. .  | ||         |... ||  |.| || ||. ||.|. .   .|...| ..|   .|..|.  ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTFKIANFHLAQHLNGNKYWTIEKGTKLAIRWTAPEGYALNQLSI-KSDVWSFGILLWELA
.. .   .. |. ... |. ..  ||.||   |||| .  . ||. | || .|         .       . |||     . .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKGKEPYPGMTDKEVKEAVSKGYHMPIPQGCPEPFIKLIIDCGKYNDYDRPNFKNIFD----QFDAPVL
. |. |.|   ..  |  .            ..... .|  | ...  .||    ..         | .
C-GYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK425.AA Pkinase 709-956 22 5e-19 68.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 709-956
Range on HMM: 1-293/293
Sequence Identity: 22% (66 aa)

ITSFKCLHVGKFGEIWKGDWKGKGT-VTIKTNIATNITQETFIE-----EIIKLQKLHHQNIISLYGVCIESYPFYIITEPING-----NLKQYLI---T
..  ...  | ||. .|. .|| |  | .|.    ..  .  ..     ||  ...|.| ||. ||... ..   |...|  .|      |. |.     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNP--TPAELVDIAIQVTEGMIYLGEQDYIHCDLRAINILLGDHNTF----KIANFHLAQH--LNGNKYWTIEKGTKLAIRWTAPEGYA-LNQLSIKSDV
..   .. |. ... |. .|. |. ..  ||.||   |||. ....     ||. | || .  .  |   |   ||   ... |||     .  . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYGPKVDM

WSFGILLWELATKGKEPYPGM-------TDKEVKEAVSKGYHMPIPQGCP-------------------EPFIKLIIDCGKYNDYDRPNFKNIFDQ--F
||.|..|.|... |. |.||         .. ...  .. .| ..|. |.                   |.....| .| ... ..||... |.    |
WSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF