Gene AqueK429 (A.queenslandica)

AqueK429

Species: A.queenslandica
Alias: AqueK429
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK429.AA Protein None 868 None Fasta, JSON
AqueK429.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of AqueK429.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK429.AA Death 32-104 22 2e-06 24.03 Pfam 13-87 (87) Show / Hide 
Range on Protein: 32-104
Range on HMM: 13-87/87
Sequence Identity: 22% (17 aa)

PEAKWFEFGLNLGLIHPTLEAIDA-NHRGNTSRCLMECLSKWLSK-AHHPTWQTLASALRKIEQKTVAENIEKIM
| ..| ...  ||. .  .. |   .......   .. | ||  .     | ..|..||||...  .||.|. ..
PGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL
SH2 AqueK429.AA SH2 505-577 41 2.8e-23 70.15 Pfam 6-81 (81) Show / Hide 
Range on Protein: 505-577
Range on HMM: 6-81/81
Sequence Identity: 41% (32 aa)

VSRNEAEERLSQADTQAGTFLIRDSKSKPGHHYFLSLNYRV---TIQHYRMNNEFNK-YYTSHDLKFDSLNDLVHHY
.||.|||..| .   . ||||.|.| |.||. | ||. .      ..||| ... |. || . . ||.||..||.||
ISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK429.AA SH2 503-583 36 6.3e-17 63.47 SMART 6-87 (87) Show / Hide 
Range on Protein: 503-583
Range on HMM: 6-87/87
Sequence Identity: 36% (31 aa)

KQVSRNEAEERLSQADTQAGTFLIRDSKSKPGHHYFLSLNYRVTIQHYRMNNEF-NKYYTSH--DLKFDSLNDLVHHYMMKADG
  .|| |||. | .   . |.||.||| |    .| ||. ..  ..||| . .  .|||     . ||.|| .||.||.  ..|
GNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK429.AA Src 613-860 39 6.2e-86 291.79 In-house 1-255 (255) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-255/255
Sequence Identity: 39% (100 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLT----TNNTTPAELV
|.. . .  |.||| |.   .|. .| .||  . .  .| || ||.|. || |.....|| ||..  |.||||| | .|.|  ||     . .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLN--SNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDL
|.. || .||.||... ||| ||.| |.| |..|  |.| | ||. .    . | . ..| |. |.|||||    .| .||||||||||||.|. |.|  
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYRGMTNKEAVELVSEGDHIFIPQDCPERFDQ-LMINCLKYYDDKRPNFKDIFDVL
||.||||.|... |. | .   |. ||... . .|  | .   ..|| |. ....|
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK429.AA SFK-Src 613-853 40 5.8e-84 248.61 In-house 1-248 (259) Show / Hide 
Range on Protein: 613-853
Range on HMM: 1-248/259
Sequence Identity: 40% (101 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLTT---NNTTPAELVD
|   |    | ||. ||    ..  | .||     . .| || || .. || | | | || |||   | ||.|| | .| |  ||        .   |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

ITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKY-WTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDLPY
 . ||  || || .| ..| || | |.| || |. |.. | ..  |  .   .| ..| |  |.|||||    || ||||||||||||. |. | |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

RGMTNKEAVELVSE--GDHIFIPQDCPERFDQLMINCLKYYDDKRPNF
 ||||.| .  |    |     |. ||... ..|..| .   | || |
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK429.AA TK 613-860 20 1.1e-72 242.76 In-house 1-486 (486) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-486/486
Sequence Identity: 20% (99 aa)

ITFFKCIHVGKFG---ETWKSDCKGKG--------------------------PVTIKTNIAT-NITQETFLD--------------EANILGKLH----
||. | .  | ||   | .|   .|..                          || .|.  .. . .|| |.|              ||... ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGVCTES------------YPFYIVTEPMN-GN----LKGYLTTN-----------------------------------------------
 |.||..||||||..             |..||.| |. |.    |. || ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NTTPAELVDITIQVTDGMKYLGEQ------DYIHCDLRAINILLGDHNT-----------LKIANFH---
                              . |...|. .  |. .|| || ..       ..| || | |.|.|..|.            ||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNSN-KYWTIE-----------------------KGTKLAIRWTAPEGYA---------LNRLSIKSDVWSFGILLWELATKG-DLPYRGM
     ||  ..|.  |.. .                       .|.|| |||.|||  .          .. ..||||||||.|.||. | |   .| ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------KEAVELVSEG-----------DHIFIPQ---DCP--------------ERFDQLMINCLKYYDDKRPNFKDIFDVL
.|         .| .|.. .|            . . .    .||              | ...||  | .|  ..||.|... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK429.AA Frk 613-864 40 3.3e-72 246.19 In-house 1-260 (260) Show / Hide 
Range on Protein: 613-864
Range on HMM: 1-260/260
Sequence Identity: 40% (104 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPMNGN-LKGYLT-----TNNTTPAEL
| . . .  |.||| |      . || .||  .  .  . || || |. || |  .|.|| |||   | ||.|| |  . |. ||       ..    .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKY--WTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGD
||.. ||  || || .| ||| || | |.|.|.|| .||| | ||  |  ..   .    | .. |.|||||    |. .|||||||||||| |. | | 
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

LPYRGMTNKEAVELVSEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVLITYD
.|| ||||.| .. |..|  .  | .||... ..|..| .   .||| |  .   |  | 
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK429.AA SrcA 613-860 44 1e-71 225.79 In-house 1-250 (250) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-250/250
Sequence Identity: 44% (111 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPMN-GNLKGYLTTNNTTP---AELVD
|.  . .  | ||| |     |.  | |||     .  |.||.|| |. ||.|  .. || |  |  | ||||| |. | |  .|  ..       .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

ITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDLPYR
.. || .|| |.    ||| |||| ||| |..   ||| | ||  .. | | | ..|.|  |.|||||     |  |||||||||||| || ||| .|| 
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTNKEAVELVSEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVL
|| |.| .| | .| |.  ||||||   .||. | .   . || |  .   |
GMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK429.AA Pkinase_Tyr 613-860 38 2.8e-69 235.27 Pfam 1-270 (270) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-270/270
Sequence Identity: 38% (103 aa)

ITFFKCIHVGKFGETWKSDCK-----GKGPVTIKTN--IATNIT--QETFLDEANILGKL-HHKNIISLYGVCT-ESYP--FYIVTEPMNG-NLKGYLTT
||| | .  | ||| .|  .|     .| || .|.    |.     .| |. ||.|. .| ||.||..|||||| .. |   |||.| | . .|. || .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----NTTPAELVDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHL-NSNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSF
.     . |. .|... .|. .|| || .. .|| ||.| |.|... |. ||. | ||  . |   | .  .|.|| |.|.|||  . .. ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELATKGDLP-YRGMTNKEAVELV-SEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVL
|.|.||. | |. | | ||.| | .|..  .|    .|..||.   .||  | .|  ..|| |..|   |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK429.AA Src-Echino1 613-860 38 1e-68 234.57 In-house 1-252 (252) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-252/252
Sequence Identity: 38% (98 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLTTNNTT---PAELVD
  . | |  |..|| ||   .|  || .||     ...  || |||.. |. |..|. .| || .. | ||||| | ||||. ||  ...     ..|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

ITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDLPYR
.  ..  || |||.....| || | |.|.|. |  |||.| ||. .. . | . . | || |.|||||     |  |||||||||||. |. | | .||.
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTNKEAVELVSEGDHIFIPQDCPERFDQL-MINCLKYYDDKRPNFKDIFDVL
||.|.| .. | .|  .  ...||.   .. |. |      .|| |. . | .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK429.AA Abl 613-860 37 4.2e-67 222.75 In-house 1-252 (252) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-252/252
Sequence Identity: 37% (94 aa)

ITFFKCIHVGKFGETWKSDCKGKGP-VTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLTTNNTT---PAELV
|.  . .  |..|| ...  |  .  | .||    ..  . || || |. ...|.|.. | ||||   ||||.|| | .|||  ||  .. .   .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDLPY
 .  |.. ||.|| ....|| || | | |.|.|. .|.| | ||  .. . | | . | |  |.|||||. | |. |.||||| ||.||||.|| |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

RGMTNKEAVELVSEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVL
 |.  ..  ... .|  .  |. ||.   .|| .| ..    || ||.|   .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK429.AA SrcB 613-861 39 5.1e-64 215.41 In-house 1-251 (251) Show / Hide 
Range on Protein: 613-861
Range on HMM: 1-251/251
Sequence Identity: 39% (99 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLTTNNTTPAE---LVD
. . | .  |.||| | .  ...  | .||     .  | ||.|||.. .| |. .. || | |   | ||.|| | .| |  .| |.. .  .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

ITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKYWTIEKGTKLAIRWTAPEGYALNRLSIKSDVWSFGILLWELATKGDLPYR
.. |...|| |. .. ||| |||| |||  .    ||| | ||  ...| | |   | |  |.|||||        |||||||||||| |. | | .|| 
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTNKEAVELVSEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVLI
|||| | .. ...|  .  |. |||   ..|. | |   . || |  .  || 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK429.AA TyrKc 613-860 34 2.8e-63 217.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-280/280
Sequence Identity: 34% (99 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIATNITQETFLDEANILGKL--HHKNIISLYGVCTES-------YPFYIVTEPM-NGNLKGYLTTNN--
||. | .  | ||| .|   |   .| .|.  .    .| |..||.|. ||  ||.||. ||||||..        | .||.| | .|.|| ||  .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

TTPAELVDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSN-------KYWTI--EKGTK--LAIRWTAPEGYALNRLSIKSDV
 ....|... .|. .|| || .. .|| || | |.|.|. .| ||. | |.  . .        .| .   .||.|  | |||.|||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGDLPYRG-----MTNKEAVELVSEGDHIFIPQD--------CPERFDQLMINCLKYYDDKRPNFKDIFDVL
||||...||. | |. || |     |.|.|..|.| .|.   .|..        ||.   |.|  | ..  ..||.|..| . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK429.AA UTK 650-860 32 3.8e-62 211.39 In-house 47-296 (296) Show / Hide 
Range on Protein: 650-860
Range on HMM: 47-296/296
Sequence Identity: 32% (80 aa)

QE---TFLDEAN---ILGKLH-HKNIISLYGVCTESYPFYIVTEPMN-GNLKGYLTTNNTTPA---------ELVDITIQVTDGMKYLGEQDYIHCDLRA
.|   .|. ||.   .....| | |.. |.|||| . |..|||| |  |.|  || ..  ||          ....   .. .|| || .. ..|.|| |
PEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAA

INILLGDH-------NTLKIANFH---LAQHLN---------SNKYWTIEKGTKLAIRWTAPEGYALN-RLSIKSDVWSFGILLWELATKGDLPYRGMTN
 |.|...|       .. |||.|    ..  .|         .  | .    ....|||.||| .. . | ..||||||||...||. | | ||| ||.|
RNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSN

KEAVELVSEGD--HIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFDVL
 .... |..|.  . . |.|||..  .||  | .|  ..||.|.|. ...
MQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK429.AA Src-Unclassified 613-860 33 2.1e-59 202.34 In-house 1-284 (284) Show / Hide 
Range on Protein: 613-860
Range on HMM: 1-284/284
Sequence Identity: 33% (95 aa)

ITFFKCIHVGKFGETWKSDCKGKGPVTIKTNIAT---NITQETFL--------DEANILGKLHHKNIISLYGVCTESYPFYIVTEPM-NGNLKGYLTTNN
.   . .  | ||| |.   .||  | .||  .        | ||         ||.|. |. | |.. ||.||..  |.||.|| | || | ..| .  
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

-TTP--AEL------------VDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHN-----TLKIANFHLA--QHLNSNKYWTIEKGTKLAIRWTAPEGY
 ...   ..            |||  ||  || || .  |.| || | |.| |. |       |.. | ||         |    .| .. . |.|||  
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNY-CMRTGAMFPWKWMAPECF

ALNRLSIKSDVWSFGILLWELATKGDLPYRGMTNKEAVELVSEGDHIFIP--QDCPERFDQ-LMINCLKYYDDKRPNFKDIFDVL
     ||||||||.||||||..|||  ||.|| |.|..| |. |     |  . ||.   . .|  |     ..|| |   .  .
IYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase AqueK429.AA S_TKc 613-861 22 2.5e-26 94.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 613-861
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

ITFFKCIHVGKFGETWKSDCKG-KGPVTIKTNIATNITQETFLDEANILGKLHHKNIISLYGVCTESYPFYIVTEPMNG---NLKGYLTTNN-------T
 .. . |  | ||. .|   |. .  | ||         |... | .|| | ||.||. ||.|. .   .|.|.| ..|   .|. |.  ..        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TPAELVDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTLKIANFHLAQHLNSNKYWTIEKGTKLAIRWTAPEGYALNRLSI-KSDVWSFGILLWELA
.. .   .. |. ....|. ..  ||.||   |||| .  ..||. | || .|         .       . |||       .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKGDLPYRGMTNKEAVELVSEGDHIFIPQDCPERFDQLMINCLKYYDDKRPNFKDIFD--------VLI
. |  |..  . ..  ...            .. . ... .||..  .|||   ...           .
C-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK429.AA Pkinase 656-860 22 8.4e-21 74.63 Pfam 50-293 (293) Show / Hide 
Range on Protein: 656-860
Range on HMM: 50-293/293
Sequence Identity: 22% (57 aa)

EANILGKLHHKNIISLYGVCTESYPFYIVTEPMNG-----NLKGYLT---TNNT--TPAELVDITIQVTDGMKYLGEQDYIHCDLRAINILLGDHNTL--
|. |. .|.|.||. ||......   |.|.| ..|      |. |..    ..   .. |. ..  |.  |..|. ..  ||.||   |||. .....  
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA

--KIANFHLAQH--LNSNKYWTIEKGTKLAIRWTAPEGYA-LNRLSIKSDVWSFGILLWELATKGDLPYRGM------TNKEAVELVSEGDHIFI-PQDC
  ||. | || .  . .|   |   ||   ... |||     .  . |.|.||.|..|.|... | .|..|       . .. .... ...  |  |..|
CVKICDFGLAKQFDY-NNS-MTTFCGT---PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWC

P-------------------ERFDQLMINCLKYYDDKRPNFKDIFDV--L
.                   | . ... .||..   |||....|.    .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF