Gene AqueK431 (A.queenslandica)

AqueK431

Species: A.queenslandica
Alias: AqueK431
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK431.AA Protein None 904 None Fasta, JSON
AqueK431.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of AqueK431.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 AqueK431.AA SH3 467-525 38 7.1e-19 69.95 SMART 1-58 (58) Show / Hide 
Range on Protein: 467-525
Range on HMM: 1-58/58
Sequence Identity: 38% (23 aa)

KLFKANYNFEGQNSDELTLKKGEVLKVVKYDEDNEWWYMHSLRTDKEGYVPINYIIPIK
. ..| |....||.|||..|||... |.. | |..||.    || .||..| ||. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK431.AA SH3_1 470-518 34 9.9e-16 56.03 Pfam 1-49 (49) Show / Hide 
Range on Protein: 470-518
Range on HMM: 1-49/49
Sequence Identity: 34% (17 aa)

KANYNFEGQNSDELTLKKGEVLKVVKYDEDNEWWYMHSLRTDKEGYVPI
.| | ...|..|||..|||....|.. ..|..||   ...| .||..| 
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 AqueK431.AA SH3_2 468-524 17 2.2e-10 39.22 Pfam 1-68 (68) Show / Hide 
Range on Protein: 468-524
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

LFKANYNFEG-QNSDE-----LTLKKGEVLKVV--KYDEDNEWWYMHSL-RTDKE--GYVPINYIIPI
....  .... .. .|     |..|||.|.||   .  ....||. .    . ..  |..|.... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK431.AA SH2 537-612 41 1.1e-26 80.16 Pfam 1-81 (81) Show / Hide 
Range on Protein: 537-612
Range on HMM: 1-81/81
Sequence Identity: 41% (34 aa)

YYH-KVSRDEAKKRLSQTITQVGTFLMRDSESKPGQYTLSLIDGF---TIWNYHISIENDK-YYLFPHVQFDSLNDLVHHY
.|| |.|| || ..| ..  . |||| |.|||.||.||||. |.     .  |.|  .... ||..  ..|.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK431.AA SH2 535-618 37 2.1e-24 88.29 SMART 1-87 (87) Show / Hide 
Range on Protein: 535-618
Range on HMM: 1-87/87
Sequence Identity: 37% (33 aa)

YIYYH-KVSRDEAKKRLSQTITQVGTFLMRDSESKPGQYTLSLIDGFTIWNYHISIEN-DKYYLFP--HVQFDSLNDLVHHYMMKADG
. .|| ..||.|| . | .   . |.|| |||||.||.|.||. ..  . .|.|  .. .|||.     ..|.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK431.AA SFK-Src 648-889 40 8e-82 242.15 In-house 1-248 (259) Show / Hide 
Range on Protein: 648-889
Range on HMM: 1-248/259
Sequence Identity: 40% (100 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLIT----SKTIPAESV
|. |.    || |. |||   ..  . .||     . .. | .|| .. || | | | || |||   | ||.|  . .  | |||      | ..|   |
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMP-QLV

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKY-WTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKEL
| | ||  || || .| ..| || | |.| |. |..|.. | ..  |  .   .| .|| |  |.|| ||  . || ||||||||||||. |.|| |   
DMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

NPYMTDKEVKEAVSK--GCHMFIPRDCPEPFDQLMINCWKHNDDERPKF
 | || .||   | .  |  |  |  ||. . ..|..||.|. |.|| |
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTF
Kinase AqueK431.AA Src 648-896 38 2.1e-74 252.2 In-house 1-255 (255) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-255/255
Sequence Identity: 38% (98 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLI----TSKTIPAESV
||... .  || || |.|  .|.    .||  . .  .. | .|| |. || | ....|| ||..  |.||||    . .| |||     ...    . .
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLN--GNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKE
|.| || .|| ||... ||| ||.| |.| ||.| .|.| | ||. .    . | . ..| |. |.|| ||  . .| .||||||||||||.|.||.|. 
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

LNPYMTDKEVKEAVSKGCHMFIPRDCPEPFDQ-LMINCWKHNDDERPKFKDIFDVL
  | || .|| ..|..| .|  |. ||. . . .|  ||.   ..|| |. ....|
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK431.AA SrcA 648-896 43 2.7e-70 221.18 In-house 1-250 (250) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-250/250
Sequence Identity: 43% (109 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLITSK----TIPAESV
|. |. .  |. || | |   |.  . |||     .  ..|..|| |. ||.|  .. || |  |  | ||||  .    | |.|   .     .| . |
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLP-QLV

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKELN
|.| || .|| |.    ||| |||| ||| ||.   ||| | ||  .. | | | . |.|  |.|| ||     |  |||||||||||| ||||||.   
DMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEY-TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPY

PYMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVL
| | ..|| | | .| ||  |.||||   .||. ||. . .||| |  .   |
PGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK431.AA Frk 648-900 38 6.7e-67 228.57 In-house 1-260 (260) Show / Hide 
Range on Protein: 648-900
Range on HMM: 1-260/260
Sequence Identity: 38% (99 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLI-----TSKTIPAES
|.. . .  || || | |    .  . .||  .  .  . |..|| |. || |  .|.|| |||   | ||.|  . .  |..||       ..    . 
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKY--WTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGK
||.| ||  || || .| ||| || | |.|.|||| .||| | ||  |  ..   .    | .. |.|| ||    |. .|||||||||||| |..| |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

ELNPYMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVLITYD
   | ||..|| . |..|  |  | .||. . ..|..||... ..|| |  .   |  | 
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK431.AA Abl 648-896 37 4e-64 212.66 In-house 1-252 (252) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-252/252
Sequence Identity: 37% (95 aa)

IKFEQCISVGQIGETWKGDCKGKGSIM-IKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLITSKTIPAESV---
|  .. .  || || ..|  |  . .. .||     .  . |.||| |. ...| |.. | ||||   ||||.|  . . || |||  ..    ..|   
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKELN
 .| |.. || || ....|| || | | |.|||. ||.| | ||  .... | | . | |  |.|| ||.   |. |.||||| ||.||||. | |    
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PYMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVL
| .  ..| . . ||  |  |. ||.   .|| .||. .  .||.||.|   .
PGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK431.AA Src-Echino1 648-896 35 5.3e-64 218.93 In-house 1-252 (252) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-252/252
Sequence Identity: 35% (91 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLITSKTI---PAESVD
 .... |  |..|| |||  .|   . .||     ...  |. || .. |. | ... .| || .. | ||||  . | ||.|||   |.     .. .|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKELNP
.  ..  || |||.....| || | |.|.|. | .|||.| ||. .. . | . . | || |.|| ||     |  |||||||||||. |.|| |.   |
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

YMTDKEVKEAVSKGCHMFIPRDCPEPFDQL-MINCWKHNDDERPKFKDIFDVL
 |...|| . | .|  |  . .||.   .. |. ||  .   || |. . | .
GMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase AqueK431.AA Pkinase_Tyr 648-896 34 2.1e-63 215.35 Pfam 1-270 (270) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-270/270
Sequence Identity: 34% (94 aa)

IKFEQCISVGQIGETWKGDCK-----GKGSIMIKTN--IATDIT--QKTFIKEASILAKL-HHINVISLYGVCT-ESYP--FYIVTGPIINRNLKDYLIT
|.| . .  |. || .|| .|     .|    .|.    |..    .. |..||.|. .| || |...|||||| .. |   |||.    . .|.||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S-----KTIPAESVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHL-NGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSF
      .  . . .....|. .|| || .. .|| ||.| |.|..| |.|||. | ||  . |   | .. .|.|| |.|..||    .. ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELVTKGKEL-NPYMTDKEVKEAV-SKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVL
|.|.||..| |..   | |.. ||.|..  .|. | .|..||..  .||  ||... ..|| |..|   |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK431.AA TK 648-896 18 4.8e-63 209.9 In-house 1-486 (486) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-486/486
Sequence Identity: 18% (89 aa)

IKFEQCISVGQIG---ETWKGDCKGKG--------------------------SIMIKTNIAT-DITQKTFIK--------------EASILAKLH----
|.... .  || |   | .||  .|..                             .|.  .. . .|. |.               ||.......    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HINVISLYGVCTES------------YPFYIVTGPIINRN----LKDYLITSK----------------------------------------------
 | |...||||||..             |..||.    . .    |.||| ...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------TIPAESVDIAIQVTDGMIYLGEQ------DYIHCDLRAINILLGEHNT-----------VKIANFH---
                                 ... . .. |. .|| || ..       ..| || | |.|.||.|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHL-NGNKYWTVEE-----------------------GTKLAIRWTPPEGYT---------LNRLSIKSDVWSFGILLWELVTKGKELNPY-M
     ||  . ..  |.....                       |.|| |||..||  .          .. ..||||||||.|.||..| |.|  .  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------KEVKEAVSKG--------------CHMFIPRDCP--------------EPFDQLMINCWKHNDDERPKFKDIFDVL
..         .|| | . .|                |  | .||              | ...||  ||... ..|| |... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK431.AA SrcB 648-897 38 1.6e-62 210.33 In-house 1-251 (251) Show / Hide 
Range on Protein: 648-897
Range on HMM: 1-251/251
Sequence Identity: 38% (98 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLIT---SKTIPAESVD
.|... .  || || | |  ...  . .||     .  . |..|| .. .| |  .. || | |   | ||.|  . .  | |.| |   ||      .|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKELNP
.. |...|| |. .. ||| |||| |||  |    ||| | ||  .. | | |  || |  |.|| ||        |||||||||||| |.|| |.   |
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

YMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVLI
 ||  || .....|  |  |  |||   ..|. |||.  .||| |  .  || 
GMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK431.AA TyrKc 648-896 32 2e-57 198.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 648-896
Range on HMM: 1-280/280
Sequence Identity: 32% (92 aa)

IKFEQCISVGQIGETWKGDCKGKGSIMIKTNIATDITQKTFIKEASILAKL--HHINVISLYGVCTES-------YPFYIVTGPIINRNLKDYLITSK--
|.... .  |. || .||  |      .|.  .    .. |..||.|. ||  || |.. ||||||..        | .||.    . .|||||  ..  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

TIPAESVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGN-------KYWTVEE--GTK--LAIRWTPPEGYTLNRLSIKSDV
  ... .....|. .|| || .. .|| || | |.|.|| .||||. | |.  .          .| .. |  |.|  | |||..||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELVTKGKELNPY-----MTDKEVKEAVSKGCHMFIPRD--------CPEPFDQLMINCWKHNDDERPKFKDIFDVL
||||...||. | |..  |      |...|| | | .|  | .| .        ||.   |.|  ||... ..|| |..| . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK431.AA UTK 687-896 31 9.3e-54 182.28 In-house 52-296 (296) Show / Hide 
Range on Protein: 687-896
Range on HMM: 52-296/296
Sequence Identity: 31% (78 aa)

TFIKEAS---ILAKLH-HINVISLYGVCTESYPFYIVTGPIINRNLKDYLITSKTIPA---ESVD------IAIQVTDGMIYLGEQDYIHCDLRAINILL
.|..||    .....| | ||. |.|||| . |..|||    | .| .|| ...  |    ....       | .. .|| || .. ..|.|| | |.|.
DFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLV

GEH-------NTVKIANFH---LAQHLN---------GNKYWTVEEGTKLAIRWTPPEGYTLN-RLSIKSDVWSFGILLWELVTKGKELNPYMTDKEVKE
..|       ...|||.|    ..  .|         .  | .  . ....|||. || .| . | ..||||||||...||..| |.   | |.. .| .
HMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWH

AVSKG--CHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFDVL
.|..|   .|. |.|||.|  .||  ||. . .||| |.|. ...
QVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK431.AA Tec 688-898 35 4.2e-51 176.09 In-house 41-254 (254) Show / Hide 
Range on Protein: 688-898
Range on HMM: 41-254/254
Sequence Identity: 35% (77 aa)

FIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIINRNLKDYLITSKTIPAESV----DIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIAN
|| || .  || | . . |||||.. .| ||||  . .  | .|| . |   ....    .. ..|  || || .. .|| || | | | |. . ||.. 
FIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSD

FHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSIKSDVWSFGILLWELVTKGKELNPYMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHND
| ..       | |   |||  ..| |||    .| | |||||.||.| ||  . ||   . |.  || |.||.|  .  |. |..   | |  ||..  
FGMTRYVLDDQY-TSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKP

DERPKFKDIFDVLIT
.||| |..  . .  
EERPTFQQLLRQITE
Kinase AqueK431.AA S_TKc 648-897 20 1.6e-16 62.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 648-897
Range on HMM: 1-231/231
Sequence Identity: 20% (55 aa)

IKFEQCISVGQIGETWKGDCKG-KGSIMIKTNIATDITQKTFIKEASILAKLHHINVISLYGVCTESYPFYIVTGPIIN--RNLKDYLITSKT------I
 .. . |  |  |. .|.  |. .    ||         .....| .|| | || |.. ||.|. .   .|.|.  . .   .|.||.   ..      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

PAESVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTVKIANFHLAQHLNGNKYWTVEEGTKLAIRWTPPEGYTLNRLSI-KSDVWSFGILLWELVT
| .   .. |. ... |. ..  ||.||   |||| |  ..||. | || .|                 . .||       .  |.|.||.|..|.|...
PEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KGKELNPYMTDKEVKEAVSKGCHMFIPRDCPEPFDQLMINCWKHNDDERPKFKDIFD--------VLI
 |. . |   ..  |  .            .... ... .|.. . ..||   ...           .
-GYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK431.AA Pkinase 648-782 21 9e-06 21.56 Pfam 1-154 (293) Show / Hide 
Range on Protein: 648-782
Range on HMM: 1-154/293
Sequence Identity: 21% (33 aa)

IKFEQCISVGQIGETWKGDCKGKGS-IMIKTNIATDITQKTFIK-----EASILAKLHHINVISLYGVCTESYPFYIVTGPIINR----NLKDYLI--TS
......|  |  |. .|.  || |    .|.    ..  .  .      |..|...|.| |.. ||......   |.|.    .      |.||.    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTI---PAESVDIAIQVTDGMIYLGEQDYIHCDLRAINILLGEHNTV----KIA
...   . |  ... |.  |. |. ..  ||.||   |||. .....    ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC
Kinase AqueK431.AA Pkinase 822-896 14 0.000775 14.65 Pfam 192-293 (293) Show / Hide 
Range on Protein: 822-896
Range on HMM: 192-293/293
Sequence Identity: 14% (15 aa)

KSDVWSFGILLWELVTKGKELNPYMTD-----KEVKEAVSKGCHMFIPRDCP-----------------------EPFDQLMINCWKHNDDERPKFKDIF
|.|.||.|..|.|....     |.  .      . .. . .  .  ...|.|                       |.. ... .|.. .  .|| ...|.
KVDMWSCGCILYEMLCGR---PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

DV--L
    .
QHPWF