AqueK432

Species: A.queenslandica
Alias: AqueK432
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK432.AA Protein None 1036 None Fasta, JSON
AqueK432.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of AqueK432.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 AqueK432.AA SH2 4-17 28 13.262153 0.66 Pfam 68-81 (81) Show / Hide
Range on Protein: 4-17
Range on HMM: 68-81/81
Sequence Identity: 28% (4 aa)

NTPFPVVSQLLQHY
.. |. ...| .||
RHKFCSLQELVEHY

SH3 AqueK432.AA SH3 598-655 36 2.4e-10 41.63 SMART 1-58 (58) Show / Hide
Range on Protein: 598-655
Range on HMM: 1-58/58
Sequence Identity: 36% (21 aa)

KLFMASYNFEGLNPHNLTLKKGEILKVAIYKDDGWWYMHSLDTNKEGYVSINYILPIE
. . | |.... ||  |..|||.|. |    |||||.    .|..||..  ||. .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID

SH3_1 AqueK432.AA SH3_1 601-646 34 5.1e-08 30.17 Pfam 1-47 (49) Show / Hide
Range on Protein: 601-646
Range on HMM: 1-47/49
Sequence Identity: 34% (16 aa)

MASYNFEGLNPHNLTLKKGEILKVAIYKDD-GWWYMHSLDTNKEGYV
 | | ... .|  |..|||.|..|   .|| .||   ...|..||..
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWF

SH3_2 AqueK432.AA SH3_2 599-654 14 1e-06 26.22 Pfam 1-68 (68) Show / Hide
Range on Protein: 599-654
Range on HMM: 1-68/68
Sequence Identity: 14% (10 aa)

LFMASYNFEG-LNPHN-----LTLKKGEILKVA---IYKDDGWWYMHSL-DTNKE--GYVSINYILPI
.. .  ....  ..       |..|||...||     ...|.||. .   .....  |.. .... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC

SH2 AqueK432.AA SH2 667-743 46 2.8e-31 93.64 Pfam 1-81 (81) Show / Hide
Range on Protein: 667-743
Range on HMM: 1-81/81
Sequence Identity: 46% (38 aa)

YYH-TVSRREAEERLNQADTQAGTFLIRDSESKPGQHYSLSVNNGV---TIKHYRIYTEFNK-YYINPHVQFDSLNDLVHHY
.||  .|| |||..|..   . ||||.|.|||.||. |.|||  .     .||||| .. |. |||   ..|.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD-YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY

SH2 AqueK432.AA SH2 665-749 41 6.4e-25 90.03 SMART 1-87 (87) Show / Hide
Range on Protein: 665-749
Range on HMM: 1-87/87
Sequence Identity: 41% (37 aa)

YIYYH-TVSRREAEERLNQADTQAGTFLIRDSESKPGQHYSLSVNNGVTIKHYRIYTEF-NKYYINP--HVQFDSLNDLVHHYMIEADG
. .||  .|| |||. |..   . |.||.|||||   ..|.|||  .  .||||| ..  .||||     ..|.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG

Kinase AqueK432.AA SFK-Src 779-1031 39 6.5e-85 251.5 In-house 1-259 (259) Show / Hide
Range on Protein: 779-1031
Range on HMM: 1-259/259
Sequence Identity: 39% (103 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPM-NENLKDYLIS----NNTMPANLV
|.  .   .| ||. |||   ..  | .||     . .. || |  .. |  | | | ||  ||   | ||.|| | .  | ||| .      .||  ||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQ-LV

DIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKY-QILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEP
| | |   || || .| ..| || | |.| || |..|.. | ..  |  .      .|  |  |||||||  . .| ||||||||||||. |. | |  |
DMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIP

YPGMTDEEVKEAVSS-KGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVLVKHS
|||||  ||   |   .|| || |.|||  . ..| .||.    .|| |   .. .    
YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF

Kinase AqueK432.AA Src 779-1027 40 3.2e-84 286.05 In-house 1-255 (255) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-255/255
Sequence Identity: 40% (104 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNEN-LKDYLI----SNNTMPANLV
||. . . .| ||| |.|  .|. .| .||  . .  .. || | .|. |. |.....||  |..  |.||||| |... | |||       .    .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLN--GKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKE
|.| |  .|| ||... ||| ||.| |.| |..|..|.| | ||. .      |   ..  |. |||||||  .  | .||||||||||||.|. |.|. 
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY-CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV

PYPGMTDEEVKEAVSSKGYHMPIPQNCPKPFKQ-LMPNCWKIYENERPNFRDILVVL
|||||| .|| ..| ..||.|| |.|||. . . .|  ||.    .|| |  .  .|
PYPGMTNHEVLQQV-ERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase AqueK432.AA Pkinase_Tyr 779-1027 37 6.8e-79 267.82 Pfam 1-270 (270) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-270/270
Sequence Identity: 37% (102 aa)

IKFSQCINAGWFGETWKGDCK-----GKGPVTIKTN--IATDIT--QKTFLDETNILVKF-YHKNIISLYGACT-ESYP--FYIVTEPMNE-NLKDYLIS
|.| . . .| ||| .|| .|     .| || .|.    |..    .. |. | .|. .. .|.||..|||.|| .. |   |||.| |   .|.||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----NTMPANLVDIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQ-ILKESTKVAIKWTAPEGYTLSRLSIKSDVWSF
.     .  .  |.....|  .|| || .. .|| ||.| |.|... |.|||. | ||  .  . |    ....|. |||.|||    .. ..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLWELATKGKEP-YPGMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVL
|.|.||. | |..| ||||..|||.|..  .|| ||.|.|||..  .||  ||.   ..|| |..|.  |
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK432.AA SrcA 779-1027 43 7.1e-75 235.91 In-house 1-250 (250) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-250/250
Sequence Identity: 43% (111 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNE-NLKDYLISN---NTMPANLVD
|.  . .  | ||| | |   |.  | |||     .  ..||.|  |. |  |  .. ||    |  | ||||| |..  | |.|  .   . .  .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEPYP
.| |  .|| |.    ||| |||| ||| |.. | ||| | ||  ..   |   .  .|  |||||||     |  |||||||||||| || |||. |||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTA-RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP

GMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVL
|| . || | |  .||||| ||.||.   .||  ||.   .||| |  .   |
GMNNREVLEQV-ERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL

Kinase AqueK432.AA Frk 779-1031 40 2.4e-74 253.3 In-house 1-260 (260) Show / Hide
Range on Protein: 779-1031
Range on HMM: 1-260/260
Sequence Identity: 40% (106 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNEN-LKDYLI-----SNNTMPANL
|.. . . .| ||| | |    . || .||  .  .  . || |  |. |  |  .|.||  ||   | ||.|| | .. |..||       ..     |
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKY--QILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGK
||.| |   || || .| ||| || | |.|.|.|||.||| | ||  |   .      .   .. |||||||    .. .|||||||||||| |. | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

EPYPGMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVLVKHS
 ||||||. || . | ..|| || | |||. . ..| .||.   ..|| |  .   | .. 
MPYPGMTNAEVLQMV-DHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF

Kinase AqueK432.AA TK 779-1027 19 7.1e-73 243.43 In-house 1-486 (486) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-486/486
Sequence Identity: 19% (93 aa)

IKFSQCINAGWFG---ETWKGDCKGKG--------------------------PVTIKTNIAT-DITQKTFLD--------------ETNILVKFY----
|.. . . .|.||   | .||  .|..                          || .|.  .. . .|. |.|              | ... ..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGACTES------------YPFYIVTEPMN-EN----LKDYLISN-----------------------------------------------
 |.||..|||.||..             |..||.| |.  .    |.||| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NTMPANLVDIAIQATDGMIYLGEQ------DYIHCDLRAENILLGDHNI-----------VKIANFD---
                              .  .. |. .. |. .|| || ..       ..| || | |.|.|..|.           .||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAQHLNGKKYQILKE------------------------STKVAIKWTAPEGYT---------LSRLSIKSDVWSFGILLWELATKGKEPYPG-M
     ||  .. ...   |.                        ..|. |.|.|||  .           . ..||||||||.|.||. | |.|||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------EEVKEAVSS-------------KGYHMPIPQNCP--------------KPFKQLMPNCWKIYENERPNFRDILVVL
..         .|| | . .              .. || |..||              . . .||  ||.   ..||.|....  |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK432.AA Src-Echino1 779-1027 39 2e-67 230.3 In-house 1-252 (252) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-252/252
Sequence Identity: 39% (100 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPM-NENLKDYLISNNTM---PANLVD
 .. . |  | .|| |||  .|  || .||     ...  || | |.. |  |..|. .|  | .. | ||||| | | ||.||| ....     . |.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEPYP
.  .   || |||.....| || | |.|.|. |..|||.| ||. ..   | . |.  |. |||||||     |  |||||||||||. |. | |. |||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVY-CGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYP

GMTDEEVKEAVSSKGYHMPIPQNCPKPFKQL-MPNCWKIYENERPNFRDILVVL
||.. || . |  .|| || ...||    .. |  ||      || |. .   .
GMMNREVLDQV-DRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF

Kinase AqueK432.AA SrcB 779-1028 39 6.7e-66 221.88 In-house 1-251 (251) Show / Hide
Range on Protein: 779-1028
Range on HMM: 1-251/251
Sequence Identity: 39% (101 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNE-NLKDYLISNNTMPAN---LVD
.|. . . || ||| | |  ...  | .||     .  . ||.| |.. .  |. .. ||   |   | ||.|| |..  | |.| ...    .   |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEPYP
.. | ..|| |. .. ||| |||| |||  .  . ||| | ||  ..   |   .|  |  |||||||        |||||||||||| |. | |. |||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEY-TAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYP

GMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVLV
|||  || ... ..|| || |.|||.   ..|  |||    ||| |  .  || 
GMTNPEVIRNL-ERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD

Kinase AqueK432.AA Abl 779-1027 38 8.3e-66 218.35 In-house 1-252 (252) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-252/252
Sequence Identity: 38% (98 aa)

IKFSQCINAGWFGETWKGDCKGKGP-VTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPM-NENLKDYLISNNTM---PANLV
|   . .  | .|| ..|  |  .  | .||     .  . || |  |. .  |.|.. | | ||   ||||.|| | . || ||| ...     .  |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEPY
 .| | . || || ....|| || | | |.|.|.|||.| | ||  ...  |   .   |  |||||||.    . |.||||| ||.||||.|| |  ||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTY-TAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PGMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVL
||.  ..| . .  ||| |  |. ||.   .|| .||.  . .|| |..|   .
PGIDLSHVYHKL-EKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM

Kinase AqueK432.AA TyrKc 779-1027 34 9.6e-66 225.65 SMART 1-280 (280) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-280/280
Sequence Identity: 34% (97 aa)

IKFSQCINAGWFGETWKGDCKGKGPVTIKTNIATDITQKTFLDETNILVKF--YHKNIISLYGACTES-------YPFYIVTEPM-NENLKDYLISNN--
|.. . .  | ||| .||  |   .| .|.  .    .. |..| .|. |.   |.||. |||.||..        | .||.| | . .||||| ..   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

TMPANLVDIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGK-------KYQILKE--STK--VAIKWTAPEGYTLSRLSIKSDV
  .. |.....|. .|| || .. .|| || | |.|.|. ..|||. | |.  .  .       .|   ||  ..|  . |.|.|||    .. ..||||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSFGILLWELATKGKEPYPG-----MTDEEVKEAVSSKGYHMPIPQN--------CPKPFKQLMPNCWKIYENERPNFRDILVVL
||||...||. | |..||||     |...|| | |  .|| ||.|.|        ||.   |.|  ||.   ..||.|..|   .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK432.AA UTK 779-1027 29 8.5e-63 213.66 In-house 1-296 (296) Show / Hide
Range on Protein: 779-1027
Range on HMM: 1-296/296
Sequence Identity: 29% (88 aa)

IKFSQCINAGWFGETWKGDCK------GKGPVTIKTNIATDITQKT------FLDETN---ILVKFY-HKNIISLYGACTESYPFYIVTEPMN-ENLKDY
....... .| |||  |.. .      ..  | .|.. ... .|..      |. |..   .. .|. | |.. |.| || . |..|||| |   .| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LISNNTMPA---------NLVDIAIQATDGMIYLGEQDYIHCDLRAENILLGDH-------NIVKIANFD---LAQHLN---------GKKYQILKESTK
| ..   |           ... | .  .|| || .. ..|.|| | |.|...|       ...|||.|    ..  .|         .  |    . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

VAIKWTAPEGYTLS-RLSIKSDVWSFGILLWELATKGKEPYPGMTDEEVKEAVSSKG-YHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVL
..|.|.||| .|   | ..||||||||...||. | |. |||||....| ..|. .| |.|| |. || |  .||  ||.    |||.|.|.. ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase AqueK432.AA SRM 780-1028 39 5.2e-60 199.36 In-house 2-253 (253) Show / Hide
Range on Protein: 780-1028
Range on HMM: 2-253/253
Sequence Identity: 39% (100 aa)

KFSQCINAGWFGETWKGDCKGKGPVTIKTNIATD-ITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNE-NLKDYLISNNTMP---ANLVD
 . .   .|.||| | |  ||. .| ||     . . |...  |   . |  || ||.|.  |.   | ||.|| |   ||  || . .       .|.|
TLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLLD

IAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSIKSDVWSFGILLWELATKGKEPYP
.| |   || || || ||| || | |.| || |. |.. | ||  .    |    .. .. .||||||       |.|||||||||||.|. |.|  |||
FACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDH-NIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILVVLV
|||  |    . ..|| || |  ||     ||  ||.    .|| |.|    | 
GMTNHETFQQI-DRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT

Kinase AqueK432.AA S_TKc 779-1034 22 1.8e-26 95.15 SMART 1-231 (231) Show / Hide
Range on Protein: 779-1034
Range on HMM: 1-231/231
Sequence Identity: 22% (60 aa)

IKFSQCINAGWFGETWKGDCKG-KGPVTIKTNIATDITQKTFLDETNILVKFYHKNIISLYGACTESYPFYIVTEPMNE---NLKDYLISNN-------T
 .. . |  | ||. .|.  |. .  | ||         .... | .|| |  |.||. ||... .   .|.|.| ..    .|.||. ...        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

MPANLVDIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIVKIANFDLAQHLNGKKYQILKESTKVAIKWTAPEGYTLSRLSI-KSDVWSFGILLWELA
 .     .. |  ... |. ..  ||.||  ||||| .   .||. | || .|          .  .   . |||       .  |.|.||.|..|.|..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TKGKEPYPGMTDEEVKEAVSSKGYHMPIPQNCPKPFKQLMPNCWKIYENERPNFRDILV--VLVKHSRYA
. |. |.|  ..... . .             ....|... .|..   ..||   ..|   ...|   . 
C-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK432.AA Pkinase 952-1027 19 6.9e-09 32.5 Pfam 192-293 (293) Show / Hide
Range on Protein: 952-1027
Range on HMM: 192-293/293
Sequence Identity: 19% (20 aa)

KSDVWSFGILLWELATKGKEPYPGM------TDEEVKEAVSSKGYHMPIPQNCP-------------------KPFKQLMPNCWKIYENERPNFRDILVV
|.|.||.|..|.|... |. |.||       .. .. . . .. .| ..|. |.                   ...|... .|..   ..||....||  
KVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--L
  .
PWF

Kinase AqueK432.AA Pkinase 822-912 24 2e-06 23.49 Pfam 50-154 (293) Show / Hide
Range on Protein: 822-912
Range on HMM: 50-154/293
Sequence Identity: 24% (26 aa)

ETNILVKFYHKNIISLYGACTESYPFYIVTEPMNE-----NLKDYLI--SNNTM---PANLVDIAIQATDGMIYLGEQDYIHCDLRAENILLGDHNIV--
|  |. .. |.||. ||......   |.|.| ..       |.||.   .....   .  . ... |   |. |. ..  ||.||  ||||. ... .  
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA

--KIA
  ||.
CVKIC