Gene AqueK437 (A.queenslandica)

AqueK437

Species: A.queenslandica
Alias: AqueK437
External Links:
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Aque1

Sequence

Name Sequence Type Origin Length Description Download
AqueK437.AA Protein None 1170 None Fasta, JSON
AqueK437.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of AqueK437.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Death AqueK437.AA Death 49-125 23 0.000761 15.17 Pfam 13-87 (87) Show / Hide 
Range on Protein: 49-125
Range on HMM: 13-87/87
Sequence Identity: 23% (18 aa)

PEAKWFEFGLNIGLLYPTLETIEA-NHRGNTSRCLMECLSKWLSKADENVHPPTWQTLAGALRKLEAKTVAENIEKTV
| ..| ...  .|. .  ...||  .......   .. | ||  . ..|    | ..|. ||||..   .||.|.  .
PGKDWRRLARKLGMSDNEIDQIEHDQNPHDLRSQTYQMLWKWEQRHGKN---ATVDHLIEALRKMGRRDCAEKIQSWL
SH3_2 AqueK437.AA SH3_2 628-650 18 15.050838 1.31 Pfam 1-32 (68) Show / Hide 
Range on Protein: 628-650
Range on HMM: 1-32/68
Sequence Identity: 18% (6 aa)

ICVAEDDYND----TA-----ISFKKGELLEL
 ...  ||.     .      ..||||.....
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKV
SH3 AqueK437.AA SH3 729-784 25 3.5e-08 34.44 SMART 1-58 (58) Show / Hide 
Range on Protein: 729-784
Range on HMM: 1-58/58
Sequence Identity: 25% (15 aa)

KLFVACQNFEK--VQELTLKKGEVLRIAENSSDEWWYIHSLHTGNSGYVQINHMLPIE
. ..|  ...    .||..|||..... | ..|.||.    .||. |..  |.  .|.
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 AqueK437.AA SH3_1 741-775 36 6e-06 23.13 Pfam 12-47 (49) Show / Hide 
Range on Protein: 741-775
Range on HMM: 12-47/49
Sequence Identity: 36% (13 aa)

QELTLKKGEVLRIAENSSD-EWWYIHSLHTGNSGYV
.||..|||... . | | | .||   .. ||  |..
DELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWF
SH3_2 AqueK437.AA SH3_2 730-783 16 7e-06 23.56 Pfam 1-68 (68) Show / Hide 
Range on Protein: 730-783
Range on HMM: 1-68/68
Sequence Identity: 16% (11 aa)

LFVACQNFEK---VQE-----LTLKKGEVLRIA---ENSSDEWWYIHSL-HTGNS--GYVQINHMLPI
.........     .|     |..|||.|...    . ..|.||. .    .|    |.. .... ..
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 AqueK437.AA SH2 800-868 38 1.7e-20 61.99 Pfam 9-81 (81) Show / Hide 
Range on Protein: 800-868
Range on HMM: 9-81/81
Sequence Identity: 38% (28 aa)

ADAEKQLKKATAQVGTFLIRNSKSNPVKYTLSLNDGF---TIRKFHVYIEFNK-YYIDSRVRFDSLNDLVHHY
..||..|.. . . ||||.| | |.|  ||||. |.     .. ...  . |. |||  |..|.||..||.||
QEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 AqueK437.AA SH2 794-874 34 1.8e-17 65.27 SMART 1-87 (87) Show / Hide 
Range on Protein: 794-874
Range on HMM: 1-87/87
Sequence Identity: 34% (30 aa)

YIYFHIA----DAEKQLKKATAQVGTFLIRNSKSNPVKYTLSLNDGFTIRKFHVYIEF-NKYYIDS--RVRFDSLNDLVHHYMMEADG
. ..|      .||. ||.   . |.||.| | ||| .|.||. ..  .. ...  .  .|||||   |..|.|| .||.||.  ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase AqueK437.AA SFK-Src 904-1159 35 5.3e-63 185.31 In-house 1-259 (259) Show / Hide 
Range on Protein: 904-1159
Range on HMM: 1-259/259
Sequence Identity: 35% (94 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPI-NQNLRNHVNM---NKLTLAELVD
 .      .||||...||   .   | .||       .| ||.|  .. |  | | | || .|    | ||.|| . .  |           |..  |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKY-WTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKEK
 | ||  || || .| ..| || | |||  |  |..|.. |  .  |  .   .||.||  |    || |||  .  | ||||||||||||. |.|    
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGD-NNVCKVGDFGMSRVLAQDDEGYTAHEG-AKF-PIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGR

NELYSGMTNEEVWEAVLK--GHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDLVNHR
   | |||| ||   | .  |     |. ||. . ..| .||... |.|| | . .. . .  
IP-YPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase AqueK437.AA Src 904-1155 36 1.1e-61 208.32 In-house 1-255 (255) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-255/255
Sequence Identity: 36% (94 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQN-----LRNHVNMNKLTLAELV
. .   . .||||| ..|  .|  .| .||  . .  .| ||.| . . |. |.....|| .| .. |.|||||  ...     |..     .| | .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLK-GKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKE
|.| || .|| ||... ||| ||.| |||  ...| .|.| |  |  .| ..   .|..|  |.   || |||  .  | .||||||||||||.|.| . 
DMAAQVAEGMAYLESMNYIHRDLAARNVLV-GENNVCKVADFGLARLIKEDDDEYCARHG-AKF-PIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYG

KNELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQ-LMANCWKQNDDERPNFNNILVDL
.   | ||||.|| ..| .| .   |. ||. . . .|  ||..  ..|| |  .   |
RVP-YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase AqueK437.AA TK 904-1155 17 2.6e-61 203.97 In-house 1-486 (486) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-486/486
Sequence Identity: 17% (85 aa)

LEFSNCINAGQFG---EIFKGDCKGIG--------------------------PVTIKTNIAT-NFTQET--------------FLEETNMLEKFY----
... . . .||||   |..||  .|..                          || .|.  .. . .||               |||| ......     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNIISLYGICIED------------YPFYIVTEPIN-QN----LRNHVNMNK----------------------------------------------
 |.||..|||.| ..             |..||.|  .  .    ||..   ..                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTLAELVDIAIQVTDGMIYLGEQ------DYIHCDLRAENVLLRDHHN----------TVKIANFH---
                               ||...|. .. |. .|| || ..       ..| || | |.|. ....          ..||| |    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FALHL-KGKKYWTAEEGT---------------------TKLAALKWIAPEWHT---------LKRLSIKSDVWSFGILLWEMVAKEKNELYSGM
      |  . ... |.......                          ..| |||  .          .. ..||||||||.|.||..   .   | ||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TN---------EEVWEAVLKG--------------HHKFIPKDCP--------------EPFKQLMANCWKQNDDERPNFNNILVDL
.|         .|| | . .|              . .  |..||              | . .||  ||. . ..||.|  ..  |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK437.AA Frk 904-1159 34 2.7e-59 203.29 In-house 1-260 (260) Show / Hide 
Range on Protein: 904-1159
Range on HMM: 1-260/260
Sequence Identity: 34% (91 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQN-LRNHVN-----MNKLTLAEL
...   . .|||||.. |      || .||  .     . || |  .. |  |  .|.|| .|  . | ||.|| . .. | ...       ... . .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKE
||.| ||  || || .| ||| || | |||. . || .||| |  |  |.  .    |  .     .|| |||    .. .|||||||||||| |..   
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGE-HNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYG

KNELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDLVNHR
.   |.|||| || . | .|     | .||. . ..| .||... ..|| |  .   | .. 
RMP-YPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase AqueK437.AA UTK 904-1155 28 6.3e-57 193.29 In-house 1-296 (296) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-296/296
Sequence Identity: 28% (84 aa)

LEFSNCINAGQFGEIFKGDCKGIG------PVTIKTNI---ATNFTQE---TFLEETN---MLEKFY-HKNIISLYGICIEDYPFYIVTEPIN-----QN
....... .|.|||..|.. . .        | .|..    ......|   .|.||..   |. .|. | |.. |.|.|  . |..||||        . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRNHVNMNK-----LTLAELVDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHH------NTVKIANFH---FALHLK---------GKKYWTAEEGTT
||.|          ||| .... | .. .|| || .. ..|.|| | |.|. .|.      ...|||.|    ..  ..         .  | .| .   
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQH--Q

KLAALKWIAPEWHTLK-RLSIKSDVWSFGILLWEMVAKEKNELYSGMTNEEVWEAVLKG--HHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDL
. ....| |||  |   | ..||||||||...||...   .  | ||.|..||..|..|  .. . |.|||.|  .||  ||... .|||.|  ..  .
DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase AqueK437.AA SrcA 904-1155 39 1e-56 177.49 In-house 1-250 (250) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-250/250
Sequence Identity: 39% (100 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQ----NLRNHVNMNKLTLAELVD
..    .  |.|||.. |   |   | |||        |.||||  .. |  |  .. || .  |. | ||||| ...          .  .| | .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSEE-PIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKEKN
.| || .|| |.    ||| |||| |.|  ..    ||| |  |  ..   | ||. |.     .|| |||     |  |||||||||||| |.| | . 
MAAQVAEGMAYMERMNYIHRDLRAANILVGENL-ICKIADFGLARLIEDNEY-TARQGAK--FPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRV

ELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDL
  | || | || | | .| |   |.||||   .||  ||... .||| |  .   |
P-YPGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase AqueK437.AA TyrKc 904-1155 28 2.4e-55 191.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKF--YHKNIISLYGICIED-------YPFYIVTEPINQ-NLRNHVNMNK--
...   .  |.|||..||  |   .| .|.  .    .| |..| ... |.   |.||. |||.|...        | .||.|     .|...   ..  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTLAELVDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGK-------KYWTAEE--GTTKLAALKWIAPEWHTLKRLSIKSD
|....|.....|. .|| || .. .|| || | |.|. . | ||||. |  .  .. .       .| .. |  |.  .  ..| |||    .. ..|||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILLWEMVAKEKNELYSG-----MTNEEVWEAVLKGHHKFIPKD--------CPEPFKQLMANCWKQNDDERPNFNNILVDL
|||||...||.    . . |.|     |.|.|| | | .|.   .|..        ||.   |.|  ||. . ..||.|..|  ..
VWSFGVCMWEIFTYGQ-QPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK437.AA Src-Echino1 904-1156 35 6.7e-52 178.31 In-house 1-252 (252) Show / Hide 
Range on Protein: 904-1156
Range on HMM: 1-252/252
Sequence Identity: 35% (92 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPI-NQNLRNHVNMNKLT---LAELVD
|.. . |  |..||..||  .|  || .||      ..  || | |.. |  |..|. .| .| .  | ||||| . | ||....  .|     ...|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKEKN
.  ..  || |||.....| || | |||. .. | .|||.|  |  ..   | . .    ||  .|| |||     |  |||||||||||. |||   . 
MGAHIASGMDYLGSKNVVHRDLAARNVLV-GKGNVCKIADFGLARMMQKDVYCGKQ--GAKL-PIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRY

ELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQL-MANCWKQNDDERPNFNNILVDLV
  | ||.| || . | .|.    ...||.   .. |  || ..   || | . | | .
P-YPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTF-EFLHDFF
Kinase AqueK437.AA SrcB 904-1156 35 4.1e-51 171.11 In-house 1-251 (251) Show / Hide 
Range on Protein: 904-1156
Range on HMM: 1-251/251
Sequence Identity: 35% (92 aa)

LEFSNCINAGQFGEIFKGDCKGIGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQ----NLRNHVNMNKLTLAELVD
| .   . ||||||.. |  ..   | .||        | ||.| |.. .  |. .. || .   . | ||.|| ...          .  ||.|  |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKEKN
.. |...|| |. .. ||| |||| |.|  .     ||| |  |  .    | || ||      .|| |||        |||||||||||| |.|   . 
MSAQIAEGMAYIERMNYIHRDLRAANILVSETL-CCKIADFGLARIIEDNEY-TAREGAK--FPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRI

ELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDLV
  | |||| || ... .|     |  |||   ..|. |||.  .||| |. .   | 
P-YPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase AqueK437.AA TKL 910-1155 20 7.4e-49 168.63 In-house 1-364 (364) Show / Hide 
Range on Protein: 910-1155
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

INAGQFGEIFKGDCKGIG---------PVTIKTNIATN----------------------------FTQETFLEETNMLEKFYHKNIISLYGICIEDYP-
|  | |||..|| ..|.|         .| .|.   .|                            . .... ||..|. .. | ||....|.|..  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYIVTEPI-NQNLRNHVNMNKLTLAELVDIAIQVTDGMIYLGEQD--------YIHCDLRAENVLLRDHHN-------------TVKI
            ..||.| . . .|.....     .  ....|...  || ||  ..         ||.||  .|.|. .. .             ..||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ANFHFALHLK---GKKYWTAEEG----------TTKLAA--LKWIAPEWHTLK----------------RLSIKSDVWSFGILLWEMVAKEKNELYSGMT
. | ..  ..   ... .   ..          ||      . | |||    .                  | |.||.||||.|||... ..   |... 
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--PYYDYP

N----------EEVWEAVLKGHHKFIP------------KDCPEPFKQLMANCWKQNDDERPNFNNILVDL
.          |. . ...||..  ||            .|||...|.||  ||... ..||.|. ||  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK437.AA Abl 904-1155 33 1.8e-48 159.58 In-house 1-252 (252) Show / Hide 
Range on Protein: 904-1155
Range on HMM: 1-252/252
Sequence Identity: 33% (86 aa)

LEFSNCINAGQFGEIFKGDCKGIGP-VTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQ-NLRNHV---NMNKLTLAELV
.   . .  ||.||...|  |  .  | .||    .   . ||.|  .. .  |.|.. | |.|  . ||||.|| . . || ...   . ..|.   |.
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSIKSDVWSFGILLWEMVAKEK
 .| |.. || || ....|| || | | |. .||  ||.| |  |  .|.  | ||. |      .|| |||    .. |.||||| ||.|||| .|   
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHH-IVKVADFGLARMMKDDTY-TAHAGAK--FPIKWTAPESLAYNKFSSKSDVWAFGVLLWE-IATYG

NELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDL
   | |.  ..|.. . ||.    |. ||.   .|| .||. .  .|| |..|   .
MSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase AqueK437.AA Pkinase_Tyr 904-1038 29 3.7e-30 102.78 Pfam 1-153 (270) Show / Hide 
Range on Protein: 904-1038
Range on HMM: 1-153/270
Sequence Identity: 29% (46 aa)

LEFSNCINAGQFGEIFKGDCK-----GIGPVTIKTN--IATNFT--QETFLEETNMLEKF-YHKNIISLYGICI-EDYP--FYIVTEPINQ-NLRNHVNM
..|   . .|.|||..|| .|     .  || .|.    |.     .| |..| ... .. .|.||..|||.|. .. |   |||.|     .|...   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N-----KLTLAELVDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIA
.     .||. .|.....|. .|| || .. .|| ||.| |.|. . . .|||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKIC
Kinase AqueK437.AA S_TKc 904-1161 21 1.6e-27 98.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 904-1161
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

LEFSNCINAGQFGEIFKGDCKG-IGPVTIKTNIATNFTQETFLEETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQ---NLRNHVNMNK-------L
 |. . |  | ||. .|.  |.    | ||         |... | ..|.|  |.||. ||... .   .|.|.| ...   .|. .   ..       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TLAELVDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNTVKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHTLKRLSI-KSDVWSFGILLW
.  .   .. |. ... |. ..  ||.||  ||.|| .   ..||. | .| .|           ||    . ..|||       .  |.|.||.|..|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMVAKEKNELYSGMTNEEVWEAVLKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILV---DLVNHRYN
||..  .   .   . ..... ..           ....|... .|.. . ..||    .|    |  .| . 
EMLC-GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK437.AA Pkinase_Tyr 1065-1155 40 8.3e-27 91.42 Pfam 179-270 (270) Show / Hide 
Range on Protein: 1065-1155
Range on HMM: 179-270/270
Sequence Identity: 40% (38 aa)

KWIAPE-WHTLKRLSIKSDVWSFGILLWEMVAKEKNEL-YSGMTNEEVWEAV-LKGHHKFIPKDCPEPFKQLMANCWKQNDDERPNFNNILVDL
|| ||| ... |  ..||||||||.|.||..   . .  | ||.|||| |..  .|.   .|..||..  .||  ||... ..|| |  |. .|
KWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK437.AA Pkinase 947-1155 20 4.3e-18 65.05 Pfam 50-293 (293) Show / Hide 
Range on Protein: 947-1155
Range on HMM: 50-293/293
Sequence Identity: 20% (51 aa)

ETNMLEKFYHKNIISLYGICIEDYPFYIVTEPINQ-----NLRNHVN---MNKL--TLAELVDIAIQVTDGMIYLGEQDYIHCDLRAENVLLRDHHNT--
|  .. .. |.||. ||... ..   |.|.|  .       |  ..     ...  .  |. ... |.  |. |. ..  ||.||  ||.|. .. ..  
EIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA

-VKIANFHFALHLKGKKYWTAEEGTTKLAALKWIAPEWHT-LKRLSIKSDVWSFGILLWEMVAKEKNELYSGM------TNEEVWEAVLKGHHKFI-PKD
 |||. | .| ...   |   .  ||    . ..|||..   .  . |.|.||.|..|.||. ..   ...|       .  .. . ....  .|  |..
CVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR--PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWW

CP-------------------EPFKQLMANCWKQNDDERPNFNNILVD--L
|.                   |..|... .|....  .||..  || .  .
CSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF