Gene AqueK445 (A.queenslandica)

AqueK445

Species: A.queenslandica
Alias: AqueK445
External Links:
Annotation:

Classification

Group: TK
Family: Tec

Sequence

Name Sequence Type Origin Length Description Download
AqueK445.AA Protein None 237 None Fasta, JSON
AqueK445.kin_dom Protein Kinase Domain None 182 None Fasta, JSON

Protein domain

Protein domains of AqueK445.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK445.AA Tec 29-210 51 1.8e-87 296.9 In-house 1-184 (254) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-184/254
Sequence Identity: 51% (94 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHLVNKTD-ILL
| . |||||| |  |  |.||.. ||||| . ||.  |.| | ||  | | .| .||.|||||. | |.||.||   .|.|| ||  ..|   |   |||
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
.| ...| .| .||...|||| |||||||||| ..|||  |  .|.| ||.|  |||.|. |.|..|||    |.|||||.|..
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAF
Kinase AqueK445.AA SFK-Src 29-210 46 6.5e-74 218.27 In-house 1-185 (259) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-185/259
Sequence Identity: 46% (86 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCN-NQHLVNKTDILL
  | | |||| |  |  | | |  .||.| .  ||  ..   .|| .| | .|.||..|| ||    |.||||||  .|||| || . . .  .    | 
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLR-MPQLV

DMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFV-PDDE-YKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
||| |. . | .||   |.|| ||||| |||| |..||| |  .| .  ||| | |  |||. ..| |||  .  ||| |||.||.
DMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSF
Kinase AqueK445.AA Pkinase_Tyr 29-210 39 2.5e-72 245.61 Pfam 1-200 (270) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-200/270
Sequence Identity: 39% (79 aa)

LSLGKELGSGEFKKVVAGQWR-----NEVDVAIKIM-EGALNE----DDLIKEATLMEKF-QHDNLVKLYGVCI-GQGP--VYIITELNGNGSLLQYLCN
...||.||.|.| .|. | |.     ....||.|.. |||  |    .|...|| .| .. .|.|.|.|||||.  ..|  .||..|.  .|.|| || .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---QHLVNKTDILLDMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFV-PDDEY-KASVGAKYAVRWSAPEVITHARFSSKSDIWS
.   .. ..  | ||.|..||...| .||. ..||| ||||||||.. |.||.. |  || . .||.| ... |.|  ..| |||.| . .|..|||.||
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

Y
.
F
Kinase AqueK445.AA Src 29-210 42 7.3e-68 229.64 In-house 1-186 (255) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-186/255
Sequence Identity: 42% (79 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLC-NNQHLVNKTDILL
. | ..||.| |  |  | |.....||.| . .| .  ... .|| .| |..|..||.|| ||    |.||.||.  .||||.||  . .    .  .|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVP--DDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
||| |. . |..||.  .||| ||||| |||. |..||. |  || .   |||| |. |||  ..| ||| |.. ||. ||| ||.
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSF
Kinase AqueK445.AA Abl 29-210 44 2.5e-60 199.77 In-house 1-184 (252) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-184/252
Sequence Identity: 44% (81 aa)

LSLGKELGSGEFKKVVAGQW-RNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHLVNKTDILL
... . || | .  |  | | | .  ||.| . | ... .. .||| .| . .| |||.| |||    | |||||   .| ||.|| ....   .  .||
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

DMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
 || ||  .|..||.  |||| |||||||||. .||||  |  ||.. || | |  |||. ..| ||| . . .||||||.| .
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAF
Kinase AqueK445.AA TK 29-210 19 2.7e-60 200.5 In-house 1-380 (486) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-380/486
Sequence Identity: 19% (73 aa)

LSLGKELGSGEFK---KVVAGQWRNE--------------------------VDVAIKIMEG--ALNEDDLIK--------------EATLMEKFQ----
. |||.||.|.|    .|  |.||..                          ..||.|..    | .... .               ||  |....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNLVKLYGVCIGQ------------GPVYIITELNGNGS----LLQYLCNNQHLVNK-----------------------------------------
 |.|.|.|||||  .            .|..|..|.  .|.    |..|| .. .  ..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------TDILLD-------------------MAIQICAAMKFLEQS------GFIHRNLAARNCLVGDRNI-----------VKVGSFS----
             |  ||.                   |. ||...| .|..       .|.||.|||||||||..|.           .|.. |     
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----SARFVPDD-EYKASV------------------------GAKYAVRWSAPEVIT---------HARFSSKSDIWSY
     || ...| .| ..                         |.|  .|| |||...         . .|..|||.||.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSF
Kinase AqueK445.AA Frk 29-210 42 1.7e-58 200.64 In-house 1-188 (260) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-188/260
Sequence Identity: 42% (79 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIME-GALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLC--NNQHLVNKTDIL
. | ..|||| | .|  |.| |.. ||.| .  |... .|...|| .| | .|  |..|| ||  . |.||||||  .|||..||   |..    .  .|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

LDMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSAR-FVPDDE--YKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
.||| |. | | .||.  .||| ||||| |||. ||.|.  |  || .. |.|  | . .||.. ..| ||| .   .|. |||.||.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSF
Kinase AqueK445.AA SFK-Abl 31-210 45 8.2e-55 177.2 In-house 3-183 (251) Show / Hide 
Range on Protein: 31-210
Range on HMM: 3-183/251
Sequence Identity: 45% (82 aa)

LGKELGSGEFKKVVAGQWRNEVDVAIK-IMEGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHLVNKTDI-LLDM
||  || |..  |  | | |   |||| | ....   |  |||  | . || |||.| |||   || ||..|   .| || ||   |  .    . ..  
LGHRLGEGQYGEVYKGIWNNHR-VAIKTIKDESMETKDFMKEAHIMKRMQHPNLVRLIGVCTREGPMYIVQEFMNYGNLLDYLQSPQSRIQIDHVSMMHC

AIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
| ||   | |||   |||| ||||||||||   .||  |  ||||  | | | .| |. ..| |||    . |. |||.||.
AQQIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARFVDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSF
Kinase AqueK445.AA Src-Unclassified 29-210 37 1.2e-53 182.31 In-house 1-213 (284) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-213/284
Sequence Identity: 37% (79 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EG---ALNEDDLI--------KEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQ
. | ..|| | |  |  | ||. ||||.| | .|    .              .|| .| |..| |||.||.||    | |||||.  ||||||.|    
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

HLVNKTDIL------------LDMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRN-----IVKVGSFSSA--RFVPDDEYKASVGAKYAVRWSAPEVIT
        .             |.| |.   |  ||  . .|| ||||| |.|. |     .|||  |  |  . . ||.| .  ||.  . | ||| ..
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

HARFSSKSDIWSY
   || |||.|||
YGNFSIKSDVWSY
Kinase AqueK445.AA Src-Echino1 29-210 38 3.6e-52 179.26 In-house 1-183 (252) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-183/252
Sequence Identity: 38% (70 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHLVNKTDILLD
| . |..|.|..  |  | |  . .||.| . |... . |.. || .| | .|...|..| ||  . |.||.|||  ||.|..|| ...    |   |.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
|  .| . | .|..  ..||.||||| |||. |..|.  |  ||.. .|.| .  |||. ..| ||| . . ||  |||.||.
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSF
Kinase AqueK445.AA SrcB 29-210 39 2.2e-50 168.61 In-house 1-182 (251) Show / Hide 
Range on Protein: 29-210
Range on HMM: 1-182/251
Sequence Identity: 39% (73 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIM-EGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNGSLLQYLCNNQHLVNKTDILLD
| | | ||.| |  |  | ..|.. ||.| | .|..  .  ..|| .| . ||| ||.|| | . . |.|||||   .|.|| .|  ..    . . |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAV-VTKEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSSKSDIWSY
|. ||   | ..|.  .||| | | | || .  . |.  |  || . |.|| |  |||. ..| ||| | .  |  |||.||.
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSF
Kinase AqueK445.AA TyrKc 29-237 26 1.3e-46 162.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-237
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

LSLGKELGSGEFKKVVAGQWRNEVDVAIKIMEGALNEDDLIKEATLMEKF--QHDNLVKLYGVCIGQ-------GPVYIITELNGNGSLLQYLCNNQHLV
..|||.||.|.| .|. |.|.  ..||.| .     . |...|| .| |.  .|.|.|.|||||. |       .|..|..|.  .|.|..|| ....  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

NKTDILLDMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDD--------EYKASV--GAK--YAVRWSAPEVITHARFSSKSDI
 ... ||....||.. | .|.. ..||| |||||||||....||.. |  .|.. ||         |...   |.|    .|| |||.| . .|..|||.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSY----------------D-----------LEWKIVGLRSQKETP------------------------------FVVFGCDKTYL
||.                .           .|.   | |  .                                 |      . ..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase AqueK445.AA S_TKc 29-237 20 6.9e-14 26.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-237
Range on HMM: 1-231/231
Sequence Identity: 20% (51 aa)

LSLGKELGSGEFKKVVAGQWRN-EVDVAIKIMEGALNEDDLIKEATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGN--GSLLQYLCNNQH----LVNK
  .....|.| | ||  .....    |||||.      .....|  ...| .|.|.||||.|.   . .|...|. ..  |.|..|......     .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

TDILLDMAIQICAAMKFLEQSGFIHRNLAARNCLVGDRNIVKVGSFSSARFVPDDEYKASVGAKYAVRWSAPEVITHARFSS-KSDIWS-----------
      .. ||| |.... . |.||| |   | |. .   .|.. | .||..                . ||||.    ..  |.|.||           
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

------YDLEWKIVGLRSQKETPFVVFGCD--------------------KTYL
      ... .|..|  |.    |.   ..                      ..
YPPFPQMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase AqueK445.AA Pkinase 29-147 21 8.8e-14 49.81 Pfam 1-132 (293) Show / Hide 
Range on Protein: 29-147
Range on HMM: 1-132/293
Sequence Identity: 21% (29 aa)

LSLGKELGSGEFKKVVAGQWRNEVD-VAIKIMEGALNEDDLIK------EATLMEKFQHDNLVKLYGVCIGQGPVYIITELNGNG----SLLQYLCNNQH
. .|. .||| | .|  ...... . ||.||..   ....  .      |. .| ...|.| |.||...   . .|...|. ..|    .|  |.   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

LVN--KTDILLDMAIQICAAMKFLEQSGFIHR
 .     . . ... ||. ..... . |.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHR
Kinase AqueK445.AA Pkinase 189-210 39 0.085314 7.43 Pfam 176-198 (293) Show / Hide 
Range on Protein: 189-210
Range on HMM: 176-198/293
Sequence Identity: 39% (9 aa)

RWSAPEVIT-HARFSSKSDIWSY
.. |||||  .   ..|.|.||.
WYMAPEVIRGGQYYGPKVDMWSC