AqueK485

Species: A.queenslandica
Alias: AqueK485
External Links:
Annotation:

Classification

Group: TKL
Family: LRRK

Sequence

Name Sequence Type Origin Length Description Download
AqueK485.AA Protein None 1884 None Fasta, JSON
AqueK485.kin_dom Protein Kinase Domain None 69 None Fasta, JSON

Protein domain

Protein domains of AqueK485.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ras AqueK485.AA Ras 71-137 24 2e-08 30.25 Pfam 76-146 (167) Show / Hide
Range on Protein: 71-137
Range on HMM: 76-146/167
Sequence Identity: 24% (18 aa)

IILFDITSHETYMELSQLLEMSHRVCP---SAHVVVIGAKADLRK--PHHVTTEEAESFCSGHRNG-TPYYEI
.. .|||..... .. . .|  .|.|.   .  .. .| |.||.    . |.|||.. |.   ..|  |..|.
LLVYDITNRQSFENVKNWWEEIRRHCDKDDNVPIMLVGNKCDLEDDQQRQVSTEEGQAFA--KEWGACPFMEC

RAB AqueK485.AA RAB 6-155 19 5.4e-07 -55.34 SMART 1-172 (172) Show / Hide
Range on Protein: 6-155
Range on HMM: 1-172/172
Sequence Identity: 19% (36 aa)

VIVAVFGCPGVGKSTFISNALEGQFERKREAGNQRYITGSVKMCGREVPVKIVEEPELTT-------------RAILS---------IILFDITSHETYM
  . . |  ||||| ...   ...|. . ..            .| .  .|..| .  .              |.| |         |. .|||..|.. 
FKIILIGDSGVGKSCLLHRFTDDKFSEQYKHT-----------IGVDFKTKTIEVDGKRVKLQIWDTAGQERFRSITSSYYRGAHGCILVYDITNRESFE

ELSQLLEMSHRVCPS----AHVVVIGAKADLRKPHHVTTEEAESFCS--GHRNGTPYY-E----IANGPTESISALFKEVLAR
 ... |.   . ...      ....| |.||..  .|.||||. ||     ..|.|.. |     .   .|.  .| .....|
NVKNWLKEIRMHANPPPENVVIMLVGNKCDLEHQRQVSTEEAQKFCCDCAEKHGMPFMFETSAKTNTNVEEAFQCLARKIYQR

Miro AqueK485.AA Miro 8-31 41 0.009897 11.96 Pfam 2-25 (140) Show / Hide
Range on Protein: 8-31
Range on HMM: 2-25/140
Sequence Identity: 41% (10 aa)

VAVFGCPGVGKSTFISNALEGQFE
|.|.| .|.|||.||. .. ..|.
VVVCGDKGCGKSSFIHQYCGEEFP

Miro AqueK485.AA Miro 71-109 20 18.273992 0.3 Pfam 98-140 (140) Show / Hide
Range on Protein: 71-109
Range on HMM: 98-140/140
Sequence Identity: 20% (9 aa)

IILFDITSHETYMELSQLLEMSHRVCPS----AHVVVIGAKAD
....| |..|.. ..| ..    .  ..      |.|.| | |
CFVYDCTDYESFNRVSNYMAWLPHFRKWGKKAIPVIVVGNKCD

LRR_1 AqueK485.AA LRR_1 266-288 37 57.981621 0.49 Pfam 1-26 (26) Show / Hide
Range on Protein: 266-288
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KTHLLQLSD-I--SLT-LIPSSFFQDL
.   | ||.    .||  ||.| |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_TYP AqueK485.AA LRR_TYP 314-337 50 1.9e-05 25.31 SMART 1-24 (24) Show / Hide
Range on Protein: 314-337
Range on HMM: 1-24/24
Sequence Identity: 50% (12 aa)

LPSLTYLNLSHNFLSSLPSYAHWG
||.|. |.||.| |..||. | .|
LPNLRELDLSNNQLTHLPPGAFQG

LRR_1 AqueK485.AA LRR_1 316-336 25 0.004237 15.16 Pfam 1-26 (26) Show / Hide
Range on Protein: 316-336
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLTYLNLSH-N--FLS-SLPS--YAHW
.|..|.||. |   |. ..|.    . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 AqueK485.AA LRR_1 293-314 29 0.031924 12.05 Pfam 1-26 (26) Show / Hide
Range on Protein: 293-314
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SITHVDFSR-N--LLC-EIPVE-LCQL
...| |.|. |   |. .|| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 AqueK485.AA LRR_1 340-354 33 1.243741 6.41 Pfam 1-18 (26) Show / Hide
Range on Protein: 340-354
Range on HMM: 1-18/26
Sequence Identity: 33% (6 aa)

HLKVLNVSH-N--KLMGD
.|..|..|. |  .| |.
NLQHLDLSGCNCCNLTGH

LRR_1 AqueK485.AA LRR_1 398-420 37 0.005493 14.76 Pfam 1-26 (26) Show / Hide
Range on Protein: 398-420
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

ALMHLDLSG-N-TKI-KSLPPE-LGLM
 | |||||| | ... ...||. .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL

ROC AqueK485.AA ROC 462-683 16 7.7e-21 66.92 In-house 1-215 (215) Show / Hide
Range on Protein: 462-683
Range on HMM: 1-215/215
Sequence Identity: 16% (45 aa)

ITSLRVVLVGPESVGKTSLVARLKGDPVDGINP----------TKGLE-VSEWKYKGD----VLRRNMVTFDLWDFTGSSRYKSVYSCFDCK-DSLHIAV
.......|.| . ||||||. .|..|. .  ..          |.| | . .|.....      .   ..| .||| |   | . .  |  .  |....|
CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSCDKGNHPTTHGIEPIQQWVLDCKDMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLV

FNINT-----GYS------E--IISWLSDIQSFSEER-------VPVLLVFTHLDSCQTRE------------VRESEKKSRSEWVKYNMSISKKPETSP
... |     ...      .  .. ||. |.|..  .        ||..|.||.| .   .            . . ..| ..    . | |. .     
WDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEHHCMQPSPVIIVGTHWDKVPRQDNKVYQHKQCCRMWQKLRNKFPNICHSW-MQIEHY-----

AFTLLASSMSQTVKSLQDIDGRSSAHERIQSSLDQMEFSGHIVPLMPLVITEPHFVSCTTG-EGISQLRKT
                                                   . . |.|.|| .||..||..
--------------------------------------------------QGFFHVDCETGCKGIDKLRHH

Miro AqueK485.AA Miro 466-484 31 0.00074 15.98 Pfam 1-19 (140) Show / Hide
Range on Protein: 466-484
Range on HMM: 1-19/140
Sequence Identity: 31% (6 aa)

RVVLVGPESVGKTSLVARL
.||..| . .||.|.....
KVVVCGDKGCGKSSFIHQY

Ras AqueK485.AA Ras 466-483 44 0.003688 12.33 Pfam 1-18 (167) Show / Hide
Range on Protein: 466-483
Range on HMM: 1-18/167
Sequence Identity: 44% (8 aa)

RVVLVGPESVGKTSLVAR
 .||.|  .|||..|. |
KLVLIGDGGVGKSCLLIR

Miro AqueK485.AA Miro 553-580 25 0.916668 4.94 Pfam 113-140 (140) Show / Hide
Range on Protein: 553-580
Range on HMM: 113-140/140
Sequence Identity: 25% (7 aa)

SEIISWLSDIQSFSEERVPVLLVFTHLD
|....||. ...   . .|| .| ...|
SNYMAWLPHFRKWGKKAIPVIVVGNKCD