Gene AqueK495 (A.queenslandica)

AqueK495

Species: A.queenslandica
Alias: AqueK495
External Links:
Annotation:

Classification

Group: TKL
Family: LRRK

Sequence

Name Sequence Type Origin Length Description Download
AqueK495.AA Protein None 1754 None Fasta, JSON
AqueK495.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of AqueK495.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_TYP AqueK495.AA LRR_TYP 299-322 37 0.000253 21.61 SMART 1-24 (24) Show / Hide 
Range on Protein: 299-322
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

LQRLQYLDLSHNAIEKLPSMLRWN
|  |. ||||.|... ||. . ..
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK495.AA LRR_1 301-321 29 0.013459 13.38 Pfam 1-26 (26) Show / Hide 
Range on Protein: 301-321
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RLQYLDLSH-N--AIE-KLPS--MLRW
.||.||||. |   .. ..|.      
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 AqueK495.AA LRR_1 280-299 28 0.401809 8.15 Pfam 3-26 (26) Show / Hide 
Range on Protein: 280-299
Range on HMM: 3-26/26
Sequence Identity: 28% (7 aa)

THINLSH-N--NM-KSVPEE-LFQL
.|..||. |  |. ...|.. . .|
QHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK495.AA LRR_TYP 323-346 45 0.491612 2.38 SMART 1-24 (24) Show / Hide 
Range on Protein: 323-346
Range on HMM: 1-24/24
Sequence Identity: 45% (11 aa)

CPKLKELNLSTNQLADERRGIIKG
 |.|.||.|| |||    .|.  |
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 AqueK495.AA LRR_1 325-336 40 4.002463 4.61 Pfam 1-15 (26) Show / Hide 
Range on Protein: 325-336
Range on HMM: 1-15/26
Sequence Identity: 40% (6 aa)

KLKELNLST-N--QL
.|..|.||  |  .|
NLQHLDLSGCNCCNL
LRR_1 AqueK495.AA LRR_1 382-404 33 0.005283 14.82 Pfam 1-26 (26) Show / Hide 
Range on Protein: 382-404
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLTTVDLSN-N-PKLT-RLPDW-VCVL
.|.. |||. | ..||  .|..    |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP AqueK495.AA LRR_TYP 380-404 40 0.418863 2.95 SMART 1-24 (24) Show / Hide 
Range on Protein: 380-404
Range on HMM: 1-24/24
Sequence Identity: 40% (10 aa)

VFSLTTVDLSNNPKLTRLPDWVCVL
  .|.. ||||| .||.||. ..  
LPNLRELDLSNN-QLTHLPPGAFQG
LRR_1 AqueK495.AA LRR_1 406-428 25 0.041935 11.63 Pfam 1-26 (26) Show / Hide 
Range on Protein: 406-428
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

HLVRLNLKG-T-PKLQ-ELPKA-LANF
.| .|.| | . ..|. ..|.  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
ROC AqueK495.AA ROC 539-596 24 1.9e-05 14.9 In-house 83-159 (215) Show / Hide 
Range on Protein: 539-596
Range on HMM: 83-159/215
Sequence Identity: 24% (19 aa)

FTLYQCFLIS-RCIYLCIWNLSD----GKEG----LQR--LVPVLRNIQSMLPG--------SRVLFVIVHSEEKPE
. ..| || . |..|| .|....    | .     ...  | . ||.|.|  |.        |.|. |  |....|.
HATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEHHCMQPSPVIIVGTHWDKVPR
COR AqueK495.AA COR 727-765 27 3.5e-05 12.4 In-house 84-123 (434) Show / Hide 
Range on Protein: 727-765
Range on HMM: 84-123/434
Sequence Identity: 27% (12 aa)

QFLHDSGTVYHYH----APNTNPTADLFILNLQWLCNTLAKIL
..|||.|...|.     .|      |...|. ||.|  ...|.
MYLHDLGHIIHFKIWDHDPML---KDFVVLDPQWFCQMMYHIF
COR AqueK495.AA COR 792-1085 10 5.9e-08 21.54 In-house 167-434 (434) Show / Hide 
Range on Protein: 792-1085
Range on HMM: 167-434/434
Sequence Identity: 10% (39 aa)

TNYHSALIGIMIKYNKLVPLDIGR--------SRFLFPSLLPSLPPPHSS-----Y---DMTKDEVVSRKILF------RYLPCCFFSHFVSRVLSYIDQ
...|  |...| |..  .|.| .         ...| |.|||.  | |..     .    .  .... |   .       .||. |...|  | ...| .
DHDHEYLVELMEKFELCYPIDPDWTHFWHQETTTYLIPQLLPDDRPQHWEWWQWPQWETNEHDCRYLRRHYHYCMDHHHMFLPAGFWPRFQVRLHHFIHD

AGAQLAVMAHPSNPPGPAEEKRKRSSSFRNTNKYKLSRRSYIISEDSEDGGADASKAISISVTTMDRQAQCGDAIRSRLDSVSKSLPRREQFSTNEDSWT
 .                                                                                         |. ...  .
MFKC---------------------------------------------------------------------------------------FYERSC-CE

TMYMFSRALIWKDGFHLEFLDG--TLCWAEFF--NESVSIICKGDEKA----KVKLLAFLLSCVQDICTEWY--INLH-------RVHYSPCYSCLKNDP
.|       .|..|  |.. ..  ... ...   . . .|   |...     . .|.. . ...|.|  .|.   .|.       .. . ||  |.....
WM-------YWRNGMVLKWEGHNKNEALVKCDNHDNKIYITVRGCQDCWIDMCCQLWQIIRQHIQHIHNSWWPWPGLQYQCQHWVCREWIPCPHCIQDHW

--EKAPFYFNLSQI---SMATDQVLTCEKCQ------------------------AVS-PLRR
     ..|... ..    .  .. ..|.||.                        ... ... 
DTCCDICYYQYDWCIRAEEMGMDSYPCPKCDQYCDAFEMMCCYQHHWHYSHDQNGQWIQRISD
Kinase AqueK495.AA TKL 1119-1402 17 1e-44 154.85 In-house 8-364 (364) Show / Hide 
Range on Protein: 1119-1402
Range on HMM: 8-364/364
Sequence Identity: 17% (71 aa)

QVYKGTYYN----------QPVAIKVFPIDSSANHFT-----------------------VLRLHRSELSVLTNISHQYLISTAG---------FLTAP-
.||||.. .          ..||.|.|..... ..                              . |. .. ...|. ...  |         .   | 
EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPV

-----LSIVFPLAPLGSLQDHLDLCPSGIGDKIS--HVLLHQVAQGLQYLHSLH--------IIHRDIKPGNILVWS-LTLS--------DGILVKITDY
     | ||  ..| ||| ..|          ..  . . ...|.|..|||| .        |||||.|. ||||.. .|          . . .||.|.
GPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDF

GSSYYIDTFGC--------------------KGSRG-TEDYMAPELYLSA-------------RKRNYDEKVDIFSFGILLFNVVTGKKFAPNFNRSRHE
| |  ... |                     ..... |  .||||.   .             ... |.||.|..||||.|. ..|...           
GLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----------

AGGRREAFLSIPHLSII---------ASAIEEQRLVGSSNQSPATLLLKDGVHPAAREGHISTCISTC---MQVILEDCLSIDPIKRPTAEGVASRL
       .  .|. ..|         . ......     .. .             .   .  . ..|   |  ...|| . || |||... . .||
------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN-----------HH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK495.AA LRRK 1120-1305 25 2.4e-36 126.05 In-house 16-279 (351) Show / Hide 
Range on Protein: 1120-1305
Range on HMM: 16-279/351
Sequence Identity: 25% (67 aa)

VYKGTYYN----------------------------QPVAIKVFPIDS------------------------------SANHFTVLRLHRSELSVLTNIS
||.... .                            |.||||.. .|.                              ...  ...|. | |.... .  
VYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWIMSHLN

HQYLISTAGFLTAPLSIVFPLAPLGSLQDHLD-LCPSG-------IGDKISHVLLHQVAQGLQYLHSLH--IIHRDIKPGNILVWSLT-------LSDGI
| ...|  ||   || .|  .||.|.|...|     .|       |.  . . .  |.| |..|||| .  ||||| |. |||.||..       . . .
HPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHV

LVKITDYGSSY--YIDTFG-CKGSRGTEDYMAPELYLSARKR---NYDEKVDIFSFGILLFNVVTGK
 .|| |.| |   .... |  ||. |.. .||||     |.    .|.||||..|||..|.  .|..
CAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEI---MRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase AqueK495.AA Pkinase 1119-1305 24 3.1e-30 107.98 Pfam 14-209 (293) Show / Hide 
Range on Protein: 1119-1305
Range on HMM: 14-209/293
Sequence Identity: 24% (50 aa)

QVYKGTYYNQP--VAIKVFPIDSSANHFTVLRLHRSELSVLTNISHQYLISTAGFLT--APLSIVFPLAPLG----SLQDHLD---LCPSGI--GDKISH
.|||..  . .  ||.|... ..    . . ....||.... ...| . . . .. .    . .|..... |    .| |..     ..  .   ..   
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGC--FYFSEWECK

VLLHQVAQGLQYLHSLHIIHRDIKPGNILVW-SLTLSDGILVKITDYGSS----YYIDTFGCKGSRGTEDYMAPELYLSARKRNYDEKVDIFSFGILLFN
  . |...||.|.||  |||||.|| |||.    ....   |||.| |..    |  ..  ...  || .|||||. .    . |. |||..|.|..|. 
FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIR--GGQYYGPKVDMWSCGCILYE

VVTGK
...|.
MLCGR
Kinase AqueK495.AA STE 1119-1305 20 4.2e-30 103.54 In-house 14-265 (359) Show / Hide 
Range on Protein: 1119-1305
Range on HMM: 14-265/359
Sequence Identity: 20% (55 aa)

QVYKGTYYNQP-----------------VAIKVFPIDSS--------ANHFT-------VLRLHRSELSVLTNIS--HQYLISTAGFLTAP---------
.|||. . ...                 .|||. .....        .   .        .     |.... . .  |.. .   |              
TVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDE

LSIVFPLAPLGSLQDHLD-LCPSGIG------------DKISHVLLHQVAQG-LQYLHSLHIIHRDIKPGNILVWSLTLSDGILVKITDYGSSYYIDT--
| |.  . . ||| | ..  .  | .             ..  . ..|. .| |.||||.|||||||||.|||.          ||..| | .  ..   
LWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCDFGVCGQLTDSM

----------------FGCKGSRGTEDYMAPELYLSAR---KRNYDEKVDIFSFGILLFNVVTGK
                  ..   ||  .||||  .  .   .  ||.|.|| |.|...   .|||
ANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
S_TKc AqueK495.AA S_TKc 1113-1404 19 1.7e-29 105.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 1113-1404
Range on HMM: 1-231/231
Sequence Identity: 19% (62 aa)

KSLIEK-------QVYKGTYYN--QPVAIKVFPIDSSANHFTVLRLHRSELSVLTNISHQYLISTAGFLT-APLSIVFPLAPL--GSLQDHLDLCPSG--
  ...|       .|||..  .  . ||||. .           .  |.|...| .  | ...   ..     | .|. ...   |.| |... ....  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IGDKISHVLLHQVAQGLQYLHSLHIIHRDIKPGNILVWSLTLSDGILVKITDYGSSYYIDTFGCKGSRGTEDYMAPELYLSARKRNYDE-KVDIFSF
   .       ...|....|.|.||..|||||.|| |||. .        .||.| |..  .     .   || .|||||.        |.  |.|. |.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL------GYGKCKCDWWSC

GILLFNVVTGKK-FAPNFNRSRHEAGGRREAFLSIPHLSIIASAIEEQRLVGSSNQSPATLLLKDGVHPAAREGHISTCISTCMQVILEDCLSIDPIKRP
|..|.  ..|.  |  . ..  .  |                                                      |  .  ... ||  || |||
GCILYEMLCGYPPFP-QMQMMFKKIG------------------------------------------------------SPEAKDFIRKCLQKDPEKRP

TAEGVAS-------RLVI
||  .            .
TA-EALQDEWDIKCHPWF
Kinase AqueK495.AA Ciliate-E2 1186-1305 25 1.5e-28 95.08 In-house 119-293 (365) Show / Hide 
Range on Protein: 1186-1305
Range on HMM: 119-293/365
Sequence Identity: 25% (47 aa)

GSLQDHLD----LCPSGIG------DKISHVLLHQVAQ---------------GLQYLHSLH-IIHRDIKPGNILVWSLTLSDGILVKITDYGSSYYIDT
|.|.|..      ... |       .|    .  |..|               .|.|||| . |||||||| |||.          .||.| | | ..|.
GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDD

FGCKGS---------------------------------RGTEDYMAPELYLSARKRN------YDEKVDIFSFGILLFNVVTGK
. ....                                  ||  ||||| . .    |      ||.|.||.|.|..|.  ..||
DNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
Kinase AqueK495.AA CAMK 1205-1305 22 6.3e-27 83.2 In-house 182-331 (425) Show / Hide 
Range on Protein: 1205-1305
Range on HMM: 182-331/425
Sequence Identity: 22% (34 aa)

HVLLHQVAQGLQYLHSLHIIHRDIKPGNILVWSLTLSDG------------ILVKITDYGSSYYIDT-------------------------FGCKGSRG
. . .|......|.||..|.|||.|| |||. .   ..               .||.| | . ..|                            .| . |
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TEDYMA-PELYLSAR-----------KRNYDEKVDIFSFGILLFNVVTGK
|  ||| ||. .. .           |. |..|.|. | |..|.  ..|.
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase AqueK495.AA TKL-Unique 1119-1305 28 1.8e-25 86.93 In-house 12-225 (290) Show / Hide 
Range on Protein: 1119-1305
Range on HMM: 12-225/290
Sequence Identity: 28% (61 aa)

QVYKGTYYNQPVAIKVFPIDSSANHFTVLRLHRSELSVLTNIS-HQYLISTAGFLT----APL--SIVFPLAPLGSLQDHLD---------LCPSGIGDK
|||||..   |||||.| .  .  ...... ...|.... ..  |  .    |. .    .|   .||    |.||| |.|.            . .  .
QVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQ

ISHVLLHQVAQGLQYLHSLH--IIHRDIKPGNILVWSLTLSDGILVKITDYGSSYYID-----TFGCK------GSRGTEDYMAPELYLSARKRNYDEKV
    . ...|||. |||..   |||||.|. |.|| .   .  . .|| | | |   .     |.. .      .  |.  .||||. |.     |.||.
QRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV-LRMNFCQYSEKS

DIFSFGILLFNVVTGK
|..|||| |   .|.|
DVYSFGIVLWEIATRK
Kinase AqueK495.AA CAMKL 1178-1305 30 1.7e-24 74.97 In-house 98-233 (297) Show / Hide 
Range on Protein: 1178-1305
Range on HMM: 98-233/297
Sequence Identity: 30% (42 aa)

IVFPLAPLGS--LQDHLDLCP---SGIGDKISHVLLHQVAQGLQYLHSLHIIHRDIKPGNILVWSLTLSDGILVKITDYGSS-YYID-----TFGCKGSR
.|  ... |.  |.|...  .     .  .  . .  |.  ...|.||..|.|||||| |||. .   .    .||.| | | .|..        .| . 
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFC

GTEDYMAPELYLSARKRNYD-EKVDIFSFGILLFNVVTGK
|.  |||||..... .. ||  |||| | |..|.. |.|.
GSPPYMAPEIFQGN-NKPYDGPKVDIWSCGVILYAMVCGY
Kinase AqueK495.AA Ciliate-E2-Unclassified 1186-1305 25 4.4e-23 76.91 In-house 106-267 (352) Show / Hide 
Range on Protein: 1186-1305
Range on HMM: 106-267/352
Sequence Identity: 25% (44 aa)

GSLQDHLDLCPS----------------GIGDKISH-----VLLHQVAQGLQYLHSLH-IIHRDIKPGNILVWSLTLSDGI--LVKITDYGSSYYID---
|.|....  ...                 . .. .       .. |. |||.|||. . |||||||| |||.     ..|    .||.|.|.|....   
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILF----DNNGKNYYIKIIDFGISKKYQQNN

---TFG-----------CKGSRGTEDYM----APELYLSARKR-NYD----EKVDIFSFGILLFNVVTGK
   |..           ..   ||  ||    |||..    .. |||    .|.||.|.|..|.  ..|.
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL----QGQNYDHSKAYKCDIWSLGVILYEMLFGY
Kinase AqueK495.AA TK 1119-1299 15 7.2e-20 62.6 In-house 17-385 (486) Show / Hide 
Range on Protein: 1119-1299
Range on HMM: 17-385/486
Sequence Identity: 15% (56 aa)

QVYKGTYYN---------------------------QPVAIKVFPIDSSANHFTVLR--LHR--------SELSVLTNIS-----HQYLISTAG------
.||||....                           .|||.|.   .....    .   .|.        .|....   .     |. ...  |      
EVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGE

--------FLTAPLSIVFPLAPLGS----LQDHLDLC---------------------------------------------------------PSGIGD
         .  |. ||  ..|.|.    |.|.|  |                                                         | .  |
PKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKD

KISHV-----------------LLHQVAQGLQYLHSL------HIIHRDIKPGNILVWSLTL------SDGILVKITDYG----------SSYYIDTFGC
 ....                   .|.|.|..||||.      ...|||.   |.|| .          .|  .||.|.|             | |.  .
LLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYY

KGS-RGTED-------------------------YMAPELYLSAR------KRNYDEKVDIFSFGILLF
. | .|| .                         .||||  .. .      .. . .| |..|||.|..
RKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMW
Kinase AqueK495.AA Ciliate-B1 1210-1305 37 1e-17 58.68 In-house 126-226 (290) Show / Hide 
Range on Protein: 1210-1305
Range on HMM: 126-226/290
Sequence Identity: 37% (39 aa)

QVAQGLQYLHSLHIIHRDIKPGNILVWSL-------TLSDGILVKITDYG-SSYYIDTFGCKGSRGTEDYMAPELYLSAR-KRNYDEKVDIFSFGILLFN
| |.|.||||.  |.|||.|| |||.             .. ..||||.| |.   .    .   ||  |||||     . . .|| |||| |||.... 
QIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEY-MMQSCVGTINYMAPEIL---NFNQQYDKKVDIWSFGCIMYE

VVTGK
  |..
IITNE
Kinase AqueK495.AA Pkinase_Tyr 1119-1228 26 1.2e-15 53.6 Pfam 14-137 (270) Show / Hide 
Range on Protein: 1119-1228
Range on HMM: 14-137/270
Sequence Identity: 26% (33 aa)

QVYKGTYY------NQPVAIKVFPIDSSANHFTVLRLHRSELSVLTNI-SHQYLISTAGFLT---AP--LSIVFPLAPLGSLQDHLDLC---PSGIGDKI
.|||||..      ..|||.|. . ...  .     . | |....... .|. ...  |  |    |  . ||....|.|.| |.|      .  .  | 
EVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

SHVLLHQVAQGLQYLHSLHIIHRDI
     .|.|.|..||.| ..||||.
LLQMCWQIAKGMEYLESKNCIHRDL
TyrKc AqueK495.AA TyrKc 1113-1402 21 4.3e-15 21.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 1113-1402
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

KSLIEK-------QVYKGTYYNQPVAIKVFPIDSSANHFTVLRLHRSELSVLTNI--SHQYLISTAGFLT---------APLSIVFPLAPLGSLQDHLDL
 .|..|       .|||||.. ..||.|.   |.       ..  ..|.......  .|. ..   |  |          || ||. ..|.|.|.|.|  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CPSGIGDKISHVLLHQVAQGLQYLHSLHIIHRDIKPGNILVWSLTLSDGILVKITDYGSSYYI----------DTFGCKGSRGTED-----YMAPELYLS
.   .  |  .   .|.|.| .|||| ..||||.   |.|| .        |||.| | | .|          |.   |...|. .      ||||    
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

ARKRNYDEKVDIFSFGILLFNVVT-GKKFAPN-----FNRSRHEAGGRREAFLSIPHL----SIIASAIEEQRLVGSSNQSPATLLLKDGVHPAAREGHI
 ... . .| |..|||.... . | |..  |.      . ..  .  ..   . .|.     |                                     
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------

STCISTCMQVILEDCLSIDPIKRPTAEGVASRL
. | .. |  | ..|   || .||| . . ...
FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK495.AA Ciliate-B1 1378-1403 37 0.000271 11.07 In-house 264-290 (290) Show / Hide 
Range on Protein: 1378-1403
Range on HMM: 264-290/290
Sequence Identity: 37% (10 aa)

QV-ILEDCLSIDPIKRPTAEGVASRLV
|. |.. ||. || .|.|.  .  || 
QQLIQKYCLQPDPENRITIDQIIDRLM
Kinase AqueK495.AA TK 1377-1402 26 0.00152 6.9 In-house 461-486 (486) Show / Hide 
Range on Protein: 1377-1402
Range on HMM: 461-486/486
Sequence Identity: 26% (7 aa)

MQVILEDCLSIDPIKRPTAEGVASRL
.. .. .| . || .||| . . ..|
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK495.AA LRRK 1375-1404 30 0.00175 8.17 In-house 322-351 (351) Show / Hide 
Range on Protein: 1375-1404
Range on HMM: 322-351/351
Sequence Identity: 30% (9 aa)

TCMQVILEDCLSIDPIKRPTAEGVASRLVI
...|  ...| . || |||... . .||  
HMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK495.AA TKL-Unique 1380-1402 30 0.033998 3.76 In-house 268-290 (290) Show / Hide 
Range on Protein: 1380-1402
Range on HMM: 268-290/290
Sequence Identity: 30% (7 aa)

ILEDCLSIDPIKRPTAEGVASRL
....|   || .||. . . .||
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK495.AA STE 1374-1396 43 0.092842 2.14 In-house 327-349 (359) Show / Hide 
Range on Protein: 1374-1396
Range on HMM: 327-349/359
Sequence Identity: 43% (10 aa)

STCMQVILEDCLSIDPIKRPTAE
| ...  .. || .|| |||||.
SPEFKDFINKCLQKDPNKRPTAS
Kinase AqueK495.AA Ciliate-B1 1119-1134 33 0.219506 0.75 In-house 14-34 (290) Show / Hide 
Range on Protein: 1119-1134
Range on HMM: 14-34/290
Sequence Identity: 33% (7 aa)

QVYKG-----TYYNQPVAIKV
||..|     ....|.||.|.
QVFYGQFCQNQQCQQEVAVKK
Kinase AqueK495.AA Pkinase_Tyr 1272-1299 35 1.447269 2.54 Pfam 181-205 (270) Show / Hide 
Range on Protein: 1272-1299
Range on HMM: 181-205/270
Sequence Identity: 35% (10 aa)

MAPELYLSARKRNYDEKVDIFSFGILLF
||||     .   . .| |. |||.|..
MAPECINYGK---FTTKSDVWSFGVLMW
Kinase AqueK495.AA Pkinase 1380-1403 32 1.537143 2.99 Pfam 269-293 (293) Show / Hide 
Range on Protein: 1380-1403
Range on HMM: 269-293/293
Sequence Identity: 32% (8 aa)

ILEDCLSIDPIKRPT-AEGVASRLV
....||  || |||| .. . .  .
FIKWCLCKDPKKRPTAEQILQHPWF