Gene AqueK534 (A.queenslandica)

AqueK534

Species: A.queenslandica
Alias: AqueK534
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK534.AA Protein None 516 None Fasta, JSON
AqueK534.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of AqueK534.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Motile_Sperm AqueK534.AA Motile_Sperm 10-83 26 7e-10 35.3 Pfam 1-68 (114) Show / Hide 
Range on Protein: 10-83
Range on HMM: 1-68/114
Sequence Identity: 26% (21 aa)

PLLLDPLDTLVFKV-A---KHPLPSVDSENGHTECLLTLTNTSLKRIGFKMKSTAVQHYGADPATGIIEPGRRLVVSV
.| .|| | ..|.      ...            | .||.|.. ||. || |.|. ..|   |  |.|.||    . .
MLHIDPPDCIFFPAPFIFDNKQ----------GTCHHTLKNPTDKRVAFKVKCTNPKRYCVRPNYGFIKPGESCQIQI
Kinase AqueK534.AA TKL 260-509 18 5.7e-51 175.66 In-house 1-364 (364) Show / Hide 
Range on Protein: 260-509
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

IGRGAYATVYEGYFRE----------QRVAVKVLHD-------------------------MIKSHHNLEVFKREVSLLARVRHPNLLLFIAVAFDHENE
||.|....|| |..|           . ||||...                          . ..... . ...|. .. | ||||...|...... .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

R-----------PLMVTELM---T-MSLRIGYTKGIVKRLDMRQIMYDVACALHYLHSQE------EPILHRDVSSANVLLQKQDD-----------VWR
            . .|.|..   .  .. .           . ....|.|....||||..       ||.|||  |.|.|. .               |.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

GKLSDFGAANLARLS----------------------VSSAPGAEVYTAPEV------PRECVALSFDKTQKQRQEQTTKVDVFSYGVLLCEVFT--ETP
 |..||| .     |                       ..  |   . ||||       .|.| .  |. . .  | ..|.||.|.|..|.|..|  .  
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI--DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPY

Q-LPSQ---------REFSTMLRYFENRFPG------------------MHIIIKSCIERDPSLRPTMEEILQEL
. .|.           .|.     ..   .                   |  ... | . ||. ||...|||..|
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc AqueK534.AA S_TKc 254-513 25 4e-33 117.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 254-513
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

IHVKKEIGRGAYATVYEGYFRE--QRVAVKVLHDMIKSHHNLEVFKREVSLLARVRHPNLLLFIAVAFDHENERPLMVTELMTM---SLRIGYTKGI---
 .. ..||.||...|| .. ..  ..||.|...         | ..||...| . .|||.  .. |  |   ..  ||.|..     .|.    |     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VKRLDMRQIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDVWRGKLSDFGAANLARLSVSSAPGAEVYTAPEVPRECVALSFDKTQKQRQEQ
        . | .|| ..||| |.||.   |.|||.  .|.|| .     . |..||| | .     ..  |   | ||||                   
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVL----------------GY

TT-KVDVFSYGVLLCEVFTETPQLPSQREFSTMLRYFENRFPGMHIIIKSCIERDPSLRPTMEEILQ-----ELRKIF
.. |.|. | |..| | ..  |  |   .  .|..      | .  .|. | ..||. |||  |.||      .   |
GKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase AqueK534.AA Pkinase 254-509 22 6.4e-32 113.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 254-509
Range on HMM: 1-293/293
Sequence Identity: 22% (69 aa)

IHVKKEIGRGAYATVYEGYFREQR--VAVKVLHDMIKSHHNLEVFKR--EVSLLARVRHPNLLLFIAVAFDHENERPLMVTELMTM-----SLR----IG
.|... ||.|....||... .  .  ||||..    ...  ..   |  |.....|..||| . .. .  |  . .. ||.|.. .     .|       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

YTKGIV--KRLDMRQIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDV-WRGKLSDFGAA----NLARLSVSSAPGAEVYTAPEVPRECVALSFDK
  .| .     . . .|| ....| |.||.   |.|||. ..|.|. .....  . |..||| |    .      ..  |   | |||| |         
WRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---------

TQKQRQEQTTKVDVFSYGVLLCEVFTETPQLPSQ----REFSTMLRYFENRF-------------------------------PGMHIIIKSCIERDPSL
    .|. ..|||..|.|..| |...  |  |..    .  . | ......                                . .  .||.|...||. 
---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPTMEEILQE--L
||| |.|||   .
RPTAEQILQHPWF
Kinase AqueK534.AA TK 254-405 15 2.4e-24 77.87 In-house 1-307 (486) Show / Hide 
Range on Protein: 254-405
Range on HMM: 1-307/486
Sequence Identity: 15% (48 aa)

IHVKKEIGRGAYA---TVYEGYFRE---------------------------QRVAVKVLH---DMIKSHHNLEVFK---------REVSLLARVR----
|.. |..|.|..    .||.|  |.                           ..||||.|.   .| .  . .|...         .|.. ..  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLLLFIAVAFDHEN----------ERPLMVTELMTM-----SLR------IGYTKG-----------------------------------------
 |||.. ...| ...|.          | ...|.|.|       |||       ....                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------IVKRLDMRQ-------------------IMYDVACALHYLHSQ----EEPILHRDVSSANVLLQKQDD--------VWRGKLSDFGAAN-
           .   |. |                   .....||.. ||||.    .  . |||.   |.|. ...         .   |..||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LAR
    |||
GSGVLAR
Pkinase_Tyr AqueK534.AA Pkinase_Tyr 254-384 27 1.8e-23 80.11 Pfam 1-144 (270) Show / Hide 
Range on Protein: 254-384
Range on HMM: 1-144/270
Sequence Identity: 27% (41 aa)

IHVKKEIGRGAYATVYEGYFR------EQRVAVKVLHDMIKSHHN--LEVFKREVSLLARV-RHPNLLLFIAVAF-DHE-NERPLMVTELMTM-----SL
|.  |..|.||. .||.|. .      .. ||||.|     .|..  .| | ||....    .|||.. ...|   . | | ....|.|.|        |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

RIG-YTKGIVKRLDMRQIMYDVACALHYLHSQEEPILHRDVSSANVLL
|     |. ..  |. |. ...|... ||.|.   . |||.   |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLV
TyrKc AqueK534.AA TyrKc 254-509 23 2.1e-21 78.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 254-509
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

IHVKKEIGRGAYATVYEGYFREQRVAVKVLHDMIKSHHNLEVFKREVSLLARV--RHPNLLLFIAVAFDH-EN----ERPLMVTELMT---MSLRIGYTK
|. .|..|.||. .||.|  . . ||||.|..       .| | || ... ..  .|||.. ...|. .. .|    | ...|.|.|       .. ...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

GIVKRLDMRQIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDVWRGKLSDFGAANLARLSVSS----------AP----GAE--V---YTAPEVPR
. ..  |. ......||   ||||.  .. |||    |.|. ..    . | ||||   |.|   .            .    |.   .    .|||.  
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH---TVKISDFG---LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

ECVALSFDKTQKQRQEQTTKVDVFSYGVLLCEVFTETPQLPSQ-----REFSTMLRYFENR-----------------FPGMHIIIKSCIERDPSLRPTM
            .  . ||| ||.|.||.. |.||   | ..       . . ...| ...                  . |. |.|.| ..||. |||.
------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

EEILQEL
.|| ...
SEIHECF
Kinase AqueK534.AA TK-Unique 254-459 22 3.1e-20 66.56 In-house 1-234 (294) Show / Hide 
Range on Protein: 254-459
Range on HMM: 1-234/294
Sequence Identity: 22% (55 aa)

IHVKKEIGRGAYATVYEGYFRE----QRVAVKVLHDMIKSHHNLEV---FKREVSLLARVR-HPNLLLFIAVAFDHENERPLMVTELMTMS-----LRIG
. |...||.||. .|. | ...    .   ..|.. | | .....    |..| ...  .  |||.. .. .  . . |..... | . ..     ||  
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTC

YTK--GI---------------------VKRLDMRQIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDVWRGKLSDFGAA------NLARLSVSSA
. .  .                      ..  |. ......||.. ||.|| . | |||... ||||.    .   |..||| |      .    . |. 
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVC---KICDFGMARDVYTNGVYSMMCSQG

PGAEVYTAPEVPRECVALSFDKTQKQRQEQ-TTKVDVFSYGVLLCEVFT
.    . |||....            ..   ||| || |.|||. |.||
RIPIRWMAPESLKCY-----------HGMYHTTKSDVWSFGVLMWEIFT
Kinase AqueK534.AA Dicty4 254-314 38 5.8e-19 60.03 In-house 1-63 (277) Show / Hide 
Range on Protein: 254-314
Range on HMM: 1-63/277
Sequence Identity: 38% (24 aa)

IHVKKEIGRGAYATVYEGYFREQRVAVKVL--HDMIKSHHNLEVFKREVSLLARVRHPNLLLF
| . ..||.|....|| |  | . ||||.|  |    .   |. |..||....  ||||..||
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLF
Kinase AqueK534.AA MLK 353-459 28 8.3e-17 54.94 In-house 128-231 (291) Show / Hide 
Range on Protein: 353-459
Range on HMM: 128-231/291
Sequence Identity: 28% (33 aa)

QIMYDVACALHYLHSQEE-PILHRDVSSANVLLQK-----QDDVWRGKLSDFGAAN-LARL-S-VSSAPGAEVYTAPEV-PRECVALSFDKTQKQRQEQT
......| ..|||||..  || |||  | |.|.       ....   | .|||..  . .  .   |..|   . ||||  .           .. .  .
NWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTL--KICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQ-----------FRCEKYS

TKVDVFSYGVLLCEVFT
 |.||.|.||.| |..|
EKCDVWSWGVVLWEMLT
Kinase AqueK534.AA CZAK 254-315 28 5.8e-13 43.55 In-house 1-66 (279) Show / Hide 
Range on Protein: 254-315
Range on HMM: 1-66/279
Sequence Identity: 28% (19 aa)

IHVKKEIGRGAYATVYEGYFREQRVAVKVLH-DMIKSHHN---LEVFKREVSLLARVRHPNLLLFI
  . ..||.| .  || .| |.  ||.| .| .  .       ...| .||| .   .||| . |.
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFL
Kinase AqueK534.AA TKL-Unique 256-331 30 6.8e-13 41.98 In-house 1-80 (290) Show / Hide 
Range on Protein: 256-331
Range on HMM: 1-80/290
Sequence Identity: 30% (24 aa)

VKKEIGRGAYATVYEGYFREQRVAVKVLH-DMIKSHHNLEVFKREVSLLARVR-HPNLLLFIAVAFDHENERP--LMVTE
. . ||.|.|..|| | .|   ||.|..|    .|   .. |..||... . . |||....... .||    |   .|.|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVME
Kinase AqueK534.AA LISK 259-315 32 2.3e-12 36.29 In-house 1-62 (296) Show / Hide 
Range on Protein: 259-315
Range on HMM: 1-62/296
Sequence Identity: 32% (20 aa)

EIGRGAYATVYEGYFR--EQRVAVKVLH---DMIKSHHNLEVFKREVSLLARVRHPNLLLFI
|||.|... || |. |   | .|.| .|   .  .   ..  ..||| .. . |||| . |.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFM
Kinase AqueK534.AA LISK 356-399 44 6.5e-12 34.79 In-house 108-150 (296) Show / Hide 
Range on Protein: 356-399
Range on HMM: 108-150/296
Sequence Identity: 44% (20 aa)

YDVACALHYLHSQEEPILHRDVSSANVLLQ-KQDDVWRGKLSDFG
.|.||.. ||||.   |.|||  | |.|.  . ...|| |. |||
LDIACGMSYLHSMN--IIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK534.AA DRK 254-315 38 1.3e-11 35.67 In-house 1-63 (258) Show / Hide 
Range on Protein: 254-315
Range on HMM: 1-63/258
Sequence Identity: 38% (24 aa)

IHVKKEIGRGAYATVYEGYFREQRVAVKVLHDMIKS-HHNLEVFKREVSLLARVRHPNLLLFI
| .   |||| |. |. |  |   |||| |          |  |.||. |. . ||||  .|.
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFM
Kinase AqueK534.AA LRRK 353-454 26 3.8e-11 35.66 In-house 168-272 (351) Show / Hide 
Range on Protein: 353-454
Range on HMM: 168-272/351
Sequence Identity: 26% (31 aa)

QIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQD---------DVWRGKLSDFGAAN--LARLS--VSSAPGAEVYTAPEVPRECVALSFDKTQKQ-R
.|....| .. ||||.  ||.|||  | |.||.. .         .    |..|||      . ..  ..   | ... |||.            ..  .
KIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEI-----------MRYNGE

QEQTTKVDVFSYGVLL
 | |.|||..|.|..|
EEYTEKVDCYSFGMIL
Kinase AqueK534.AA LRRK 254-334 14 6.8e-11 34.75 In-house 1-138 (351) Show / Hide 
Range on Protein: 254-334
Range on HMM: 1-138/351
Sequence Identity: 14% (20 aa)

IHVKKEIGRGAYA-TVYEGYFRE----------------------------QRVAVKVLHD--------------------------------MIKSHHN
.   ..||||... .|| . .|                             | ||.|...                                 .. ....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LEVFKREVSLLARVRHPNLLLFIAVAFDHENERPLMVTELMT
.  | .||... . .|||..  . . ...    . ||.|...
FREFRHEVWIMSHLNHPNIVSLKGFCIHP----LCMVMEYAP
Kinase AqueK534.AA MLK 254-310 27 2.8e-10 31.97 In-house 1-66 (291) Show / Hide 
Range on Protein: 254-310
Range on HMM: 1-66/291
Sequence Identity: 27% (18 aa)

IHVKKEIGRGAYATVYEGYFREQR-----VAVKVLH----DMIKSHHNLEVFKREVSLLARVRHPN
| ... || |..  |. |..| ..     ||||  .    |. ..    . |..|. .|....|||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPN
Kinase AqueK534.AA TK 446-509 17 7.5e-10 28.41 In-house 376-486 (486) Show / Hide 
Range on Protein: 446-509
Range on HMM: 376-486/486
Sequence Identity: 17% (20 aa)

DVFSYGVLLCEVFT---ETPQ--LPS------QREFSTMLRYFE----------------NRFP---GMH------------------IIIKSCIERDPS
||.|.|||. |.||   |..   ...        .   ...| .                .| |   ...                  .....| ..||.
DVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPE

LRPTMEEILQEL
 |||.......|
DRPTFSQLHEQL
Kinase AqueK534.AA DRK 351-459 32 4.7e-09 26.86 In-house 100-197 (258) Show / Hide 
Range on Protein: 351-459
Range on HMM: 100-197/258
Sequence Identity: 32% (37 aa)

MRQIMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDVWRGKLSDFGAAN-----LARLSVSSAPGAEVYTAPEVPRECVALSFDKTQKQRQEQTTKV
| |.| |.|  . |||. .  |.|||  | | |    |. |. | .||| .      . .     . |    ||||| |.             |  | | 
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLV---DEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRN-------------QRYTEKA

DVFSYGVLLCEVFT
||.|... | |. |
DVYSFAIVLWECVT
Kinase AqueK534.AA TKL-Unique 357-399 42 6.5e-08 24.18 In-house 118-162 (290) Show / Hide 
Range on Protein: 357-399
Range on HMM: 118-162/290
Sequence Identity: 42% (19 aa)

DVACALHYLHSQEEPILHRDVSSANVLLQKQ--DDVWRGKLSDFG
|.| ...|||. | ||.|||  | |.|.        |. |..|||
DIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFG
Kinase AqueK534.AA TK-Unique 484-509 34 1.5e-07 22.2 In-house 269-294 (294) Show / Hide 
Range on Protein: 484-509
Range on HMM: 269-294/294
Sequence Identity: 34% (9 aa)

MHIIIKSCIERDPSLRPTMEEILQEL
|. ..|||. ..|. ||. ..|...|
MYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK534.AA TKL-Unique 487-509 43 2e-07 22.42 In-house 268-290 (290) Show / Hide 
Range on Protein: 487-509
Range on HMM: 268-290/290
Sequence Identity: 43% (10 aa)

IIKSCIERDPSLRPTMEEILQEL
.|. |  .||| ||. .||. .|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK534.AA CZAK 357-399 36 2e-06 19.6 In-house 113-167 (279) Show / Hide 
Range on Protein: 357-399
Range on HMM: 113-167/279
Sequence Identity: 36% (20 aa)

DVACALHYLHS--QEEPILHRDVSSANVLLQKQDD----------VWRGKLSDFG
|.|    |||    . |||||| || |.||    .              | .|||
DIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFG
Kinase AqueK534.AA Dicty4 488-511 42 2e-06 17.86 In-house 252-277 (277) Show / Hide 
Range on Protein: 488-511
Range on HMM: 252-277/277
Sequence Identity: 42% (11 aa)

IKSCIERDPSLRPTMEEILQE--LRK
|. | . ||. ||..|||.|.  |  
IQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK534.AA DRK 488-511 37 3e-06 17.24 In-house 235-258 (258) Show / Hide 
Range on Protein: 488-511
Range on HMM: 235-258/258
Sequence Identity: 37% (9 aa)

IKSCIERDPSLRPTMEEILQELRK
.. | . ||. ||.|.|.|. |  
MNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK534.AA MLK 482-509 32 9e-06 16.18 In-house 264-291 (291) Show / Hide 
Range on Protein: 482-509
Range on HMM: 264-291/291
Sequence Identity: 32% (9 aa)

PGMHIIIKSCIERDPSLRPTMEEILQEL
...   .| | . ||. ||.. .|.|.|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK534.AA LISK 442-456 53 1.5e-05 13.75 In-house 217-231 (296) Show / Hide 
Range on Protein: 442-456
Range on HMM: 217-231/296
Sequence Identity: 53% (8 aa)

TTKVDVFSYGVLLCE
....||||.|..|||
DESCDVFSFGIVLCE
Kinase AqueK534.AA Pkinase_Tyr 484-509 38 4.7e-05 17.74 Pfam 245-270 (270) Show / Hide 
Range on Protein: 484-509
Range on HMM: 245-270/270
Sequence Identity: 38% (10 aa)

MHIIIKSCIERDPSLRPTMEEILQEL
.. ..|.| . ||. |||..||...|
IYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK534.AA LRRK 488-511 33 6.3e-05 13.34 In-house 328-351 (351) Show / Hide 
Range on Protein: 488-511
Range on HMM: 328-351/351
Sequence Identity: 33% (8 aa)

IKSCIERDPSLRPTMEEILQELRK
|..| . ||  ||....|.. |  
IQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK534.AA Dicty4 350-459 27 0.000638 9.16 In-house 110-212 (277) Show / Hide 
Range on Protein: 350-459
Range on HMM: 110-212/277
Sequence Identity: 27% (33 aa)

DMRQ---IMYDVACALHYLHSQEEPILHRDVSSANVLLQKQDDVWRGKLSDFGAAN----LARLSV--SSAPGAEVYTAPEVPRECVALSFDKTQKQRQE
....   .. |.|  . .||.    |.|||  |.| |    |. || | .||| .        ..   ..| |   ..|||| ..             |.
LIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV---DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH-------------QP

QTTKVDVFSYGVLLCEVFT
 . |.||.|.| .| | .|
YNEKADVYSFGIVLWEILT
Kinase AqueK534.AA CZAK 487-509 39 0.000641 10.3 In-house 257-279 (279) Show / Hide 
Range on Protein: 487-509
Range on HMM: 257-279/279
Sequence Identity: 39% (9 aa)

IIKSCIERDPSLRPTMEEILQEL
.|  | .  |..||.  .||| |
LIEMCWNKNPDERPSFKQILQHL
Kinase AqueK534.AA Pkinase_Tyr 442-459 66 0.00463 10.99 Pfam 192-209 (270) Show / Hide 
Range on Protein: 442-459
Range on HMM: 192-209/270
Sequence Identity: 66% (12 aa)

TTKVDVFSYGVLLCEVFT
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TTKSDVWSFGVLMWEIFT
Kinase AqueK534.AA LISK 491-509 47 0.00559 5.29 In-house 278-296 (296) Show / Hide 
Range on Protein: 491-509
Range on HMM: 278-296/296
Sequence Identity: 47% (9 aa)

CIERDPSLRPTMEEILQEL
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CCKYDPKNRPSFKEIVQWL
Kinase AqueK534.AA CZAK 442-459 50 0.046771 3.45 In-house 200-217 (279) Show / Hide 
Range on Protein: 442-459
Range on HMM: 200-217/279
Sequence Identity: 50% (9 aa)

TTKVDVFSYGVLLCEVFT
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TEKVDVYSFGMILWCIIT
Kinase AqueK534.AA TKL-Unique 442-459 44 0.146897 1.49 In-house 206-223 (290) Show / Hide 
Range on Protein: 442-459
Range on HMM: 206-223/290
Sequence Identity: 44% (8 aa)

TTKVDVFSYGVLLCEVFT
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SEKSDVYSFGIVLWEIAT