Gene AqueK541 (A.queenslandica)

AqueK541

Species: A.queenslandica
Alias: AqueK541
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-a2

Sequence

Name Sequence Type Origin Length Description Download
AqueK541.AA Protein None 325 None Fasta, JSON
AqueK541.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of AqueK541.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK541.AA TKL 60-319 21 3.5e-55 189.66 In-house 1-364 (364) Show / Hide 
Range on Protein: 60-319
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

LGRGAWGVVWVGQFRG----------HPVAVKELHEAIRSPL-------------------------YLENIHREMSTMSQLRHPNLLQFIGAVLDHP--
.|.|. |.|. |..||           .|||| ...   .                           . . . .|.  ||.|||||..||.|.... |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------SGNPMIITEVL-DTSLRKAYDNKELTPDPGCRPVILSIMRDVAVGLNYLHC--L----PDPIIHRDVSSANVLLESKGD----------KK
         .|...|..|     ||.  .            ........|.| |.||||        . ||||||  |.|.|. ...           . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

WKTKISDFGSAN----------------------AANKAVTRLPGAEPYTAPEALAQHIMSTDS--------KKEQTTKMDVFSYGVLLCEIITCRFPDR
|. ||.||| .                         .|.  .  |   . |||.| ...  |.         ..| ..|.||.|.|..|.||.|.. | .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

DV-FQNMLHQ-------VQSINSRSMGTSD------------TQG-SLLHSLIIWCCKDDPLERPSMSQIIKQI
|  .  |. |       .. .. .   . .            ..    . .|. .|.. || .|||...|.|..
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK541.AA TK 54-319 16 4.6e-39 128.09 In-house 1-486 (486) Show / Hide 
Range on Protein: 54-319
Range on HMM: 1-486/486
Sequence Identity: 16% (79 aa)

TLSKEELGRGA---WGVVWVGQFRGH---------------------------PVAVKELHE--AIRSPLYLE-------------NIHREMSTMSQ--L
    ..||.|.   .|.|. |. ||.                           ||||| |.|  |  .   ..             .  .||. |..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLLQFIGAVLDHPS----------GNPMIITEV---------LDTSLRKAYDN--------------------------------------------
.|||.....|..... .          . .||..|          |.. |||  ..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----KELTPDPGCRPVILS-------------------IMRDVAVGLNYLHCLPD----PIIHRDVSSANVLLESKGDKKWK-------TKISDFGSA--
     .. |.| .    |.                   .....| |. ||| ..      ..|||.   |.|. ... .||.        ||.||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----------NAANKAVTRLPGAEP-------------------------YTAPEALAQHIMSTDS-KKEQTTKMDVFSYGVLLCEIIT---CRFPDRDV
          .  .  ... .|.                           ..|||.|. .. |.   ..  ||| ||.|.|||. || |     ..    
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

F---------QNMLHQVQSI--------------NSRS--MGTSD----------TQGSLLHSLIIWCCKDDPLERPSMSQIIKQI
          | .. ....               . .   .. .|          .   ... |.  |.. || .||..||. .|.
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK541.AA S_TKc 54-325 21 3e-30 107.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 54-325
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

TLSKEELGRGAWGVVWVGQFRG--HPVAVKELHEAIRSPLYLENIHREMSTMSQLRHPNLLQFIGAVLDHPSGNPMIITEVLDT---SLRKAYDNKEL--
    ...|.|| |.|. .. ..  . ||.|...         |.| ||.. ... .|||. .....  |   ..  ...| .|.   .|..  ...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

TPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSANAANKAVTRLPGAEPYTAPEALAQHIMSTDSKKEQTT-K
.. |    .. ..|. .. .|.|.| .   |||||.  .|.|| .        ||.|||.|       | . |   | ||| |             .. |
LRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-----------GYGKCK

MDVFSYGVLLCEIITCRFPDRDVFQNMLHQVQSINSRSMGTSDTQGSLLHSLIIWCCKDDPLERPSMSQIIK---QIDNISSM
 |. | |..| | .. . | .   | |....               . . ..|  |.. || .||.  .. .    | .   .
CDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK541.AA Pkinase 54-319 20 3.1e-28 100.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 54-319
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

TLSKEELGRGAWGVVWVGQFRGHP--VAVKELHEAIRSPLYLENIHR--EMSTMSQLRHPNLLQFIGAVLDHPSGNPMIITEVLDT-----SLR---KAY
   .. .|.|. |.|. .. .| .  ||||..    ...  ...  |  | . |  |.||| ....... |  .... ...| ..      .|    .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

DNKEL--TPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSA----NAANKAVTRLPGAEPYTAPEALAQHIMS
... .  ...     .. ..|. .. ||.|.|     |||||. ..|.|. ..|. . . ||.|||.|    .  |   | . |  .| ||| .      
RHGCFYFSEW-----ECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----

TDSKKEQTTKMDVFSYGVLLCEIIT--CRFPDR------DVFQNMLHQVQSINSRSMGTSDTQG-----------------SLLHSLIIWCCKDDPLERP
  . .. ..| |..|.|..| | ..    ||..      |  | .    . .....  ....                   . . ..| ||.. || .||
--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

SMSQIIKQ--I
.  || .   .
TAEQILQHPWF
Kinase AqueK541.AA TKL-Unique 58-260 27 4.2e-28 96.29 In-house 3-223 (290) Show / Hide 
Range on Protein: 58-260
Range on HMM: 3-223/290
Sequence Identity: 27% (63 aa)

EELGRGAWGVVWVGQFRGHPVAVKELH-EAIRSPLYLENIHREMSTMSQLR-HPNLLQFIGAVLDHPSGNP--MIITEVLDT-SLRKAYD---------N
. .|.|. |.|  | .|| |||.| .| ..  |.  ... ..| ..|. |. |||.....|.  ||   .|   |..| ..  ||..  .         |
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

KELTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESK-GDKKWKTKISDFGSANAANKA----VTRL-----PGAE---PYTAPEALA
.......    ..... .|.| |..||| .  ||||||  | |.|. ..    .|. ||.||| .  ..|     ....     .. .    . ||| | 
NNCKLNMQ---QRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

QHIMSTDSKKEQTTKMDVFSYGVLLCEIIT
.        .  ..| ||.|.|. | ||.|
MNF------CQYSEKSDVYSFGIVLWEIAT
Kinase AqueK541.AA Dicty4 57-261 30 1.1e-26 86.16 In-house 4-213 (277) Show / Hide 
Range on Protein: 57-261
Range on HMM: 4-213/277
Sequence Identity: 30% (69 aa)

KEELGRGAWGVVWVGQFRGHPVAVKEL--HEAIRSPLYLENIHREMSTMSQLRHPNLLQFIGAVL--DHPSGNPMIITEVL-DTSLRKAYDN------KE
 ...|.|. | |  |  ||  |||| |  |    .   |.  ..| . |...||||...| || .     .| ..| || .  ..| .   .      ..
EQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQS

LTPDPGCRPVILS---IMRDVAVGLNYLHC-LPDPIIHRDVSSANVLLESKGDKKWKTKISDFG-SA----NAANKA-VTRLPGAEPYTAPEALAQHIMS
 ..|    | |..   ...|.| |.|.|||  |. |||||  |.| |     || |. |..||| |.       .|.  .   |   ..||| .. .   
IKLD---WPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV----DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ---

TDSKKEQTTKMDVFSYGVLLCEIITC
     . . | ||.|.| .| || |.
-----PYNEKADVYSFGIVLWEILTR
Kinase AqueK541.AA STE 55-317 19 1.2e-24 84.0 In-house 1-353 (359) Show / Hide 
Range on Protein: 55-317
Range on HMM: 1-353/359
Sequence Identity: 19% (70 aa)

LSK-EELGRGAWG-VVWV-----------GQF-----RGHPVAVKELH---------------EAIRSPLYLENIHREMSTMSQLR--HPNLLQFIGAVL
. . |..|.|| | |.             |.       |  .|.|...                 .. .  ...| .|...|....  |||  ...|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DH---PSG--NPMIITEVLD-TSLRKAYDNKELTPDPGC----------RPVILSIMRDVAVG-LNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKIS
.     .   .  |. | .|  ||.. ...|  ...|             ..|  | |..  | |.||| .   |||||. .||.||          |..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL---------VKLC

DFGSANAANKAVT-------------------RLPGAEPYTAPEALAQHIMSTDSKKEQTTKMDVFSYGVLLCEIITCRFP--DRDVFQNMLHQVQSINS
||| .   .. ..                    . |   . ||| . |   .   .|. .|| |. | | ...| .| . |  |   ...|..  ... .
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R-DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

RS---------MGTSDTQG----------------------SLLHSLIIWCCKDDPLERPSMSQIIK
 .          .    .                       . ..  |  |.. || .||. || .|
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLK
Kinase AqueK541.AA TyrKc 54-319 24 5.2e-24 87.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 54-319
Range on HMM: 1-280/280
Sequence Identity: 24% (76 aa)

TLSKEELGRGAWGVVWVGQFRGHPVAVKELHEAIRSPLYLENIHREMSTMSQL--RHPNLLQFIGAVLDH-----PSGNPMIITEV-----LDTSLRKAY
   ...||.|| |.|. |. .  .|||| |.|       .| ..||.. |..|  .|||.....|.....      .. .||..|      |.  |||  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

DNKELTPDPGCRPVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSANAANKA--------VTRL----PGA--EPY--TA
..        | .  ||.. ..| | .|||    ..||||    |.|. ...      |||||| . .            . |      |    |.  .|
PK-------LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEALAQHIMSTDSKKEQTTKMDVFSYGVLLCEIITC--RFPDR-----DVFQNMLHQVQSINSRSMGTSD-------TQGSLLHSLIIWCCKDDPLERPS
||..         ... ||| ||.|.||.. || |     .          | ....|.. . .    .|           .   .. .|.. || .||.
PECI--------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPT

MSQIIKQI
.|.|....
FSEIHECF
Kinase AqueK541.AA MLK 155-264 30 1.7e-20 67.93 In-house 125-235 (291) Show / Hide 
Range on Protein: 155-264
Range on HMM: 125-235/291
Sequence Identity: 30% (36 aa)

VILSIMRDVAVGLNYLHC-LPDPIIHRDVSSANVLLES-----KGDKKWKTKISDFGSANAANKA---VTRLPGAEPYTAPEALAQHIMSTDSKKEQ-TT
...... ..| |..|||. .|.||||||  | |.|.       ...   . ||.||| .   ..     .  .|   . |||.. |      .. |. . 
HAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG---TLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQ------FRCEKYSE

KMDVFSYGVLLCEIITCRFP
| ||.|.||.| |..|.. |
KCDVWSWGVVLWEMLTREVP
Kinase AqueK541.AA CZAK 53-205 31 1.8e-18 63.81 In-house 1-167 (279) Show / Hide 
Range on Protein: 53-205
Range on HMM: 1-167/279
Sequence Identity: 31% (54 aa)

ITLSKEELGRGAWGVVWVGQFRGHPVAVKELH-EAIRSPLY---LENIHREMSTMSQLRHPNLLQFIGA-VLDHPSGNPMIITEVLD-TSLRKAYDNKE-
 .  . . |.|  | |  .  ||  ||.| .| .  |       ..   .| | || |.||| .||.||  .| |     |..|     |||.  . .  
LKFGQ-TIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGP-NHHCIVMEWMGGGSLRRLLTDHYF

-LTPDPGCRPVILSIMRDVAVGLNYLHC--LPDPIIHRDVSSANVLLESKGD---------KKWKTKISDFG
 . . |  .   ... .|.| | ||||    | ||.||| || |.||..  .         .  . ||.|||
YHKQNPHLQ---WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFG
Kinase AqueK541.AA Pkinase_Tyr 53-131 32 2.7e-18 62.6 Pfam 1-87 (270) Show / Hide 
Range on Protein: 53-131
Range on HMM: 1-87/270
Sequence Identity: 32% (29 aa)

ITLSKEELGRGAWGVVWVGQFR------GHPVAVKELHEAIRSPL-YLENIHREMSTMSQL-RHPNLLQFIGAVL--DHPSGNPMIITE
||.  ..||.|| |.|. |  .      . ||||| | |   ..  ..|   ||...|.|| .|||.....|...  . |. ...|..|
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVME
Kinase AqueK541.AA LISK 59-117 37 2.2e-16 49.52 In-house 1-64 (296) Show / Hide 
Range on Protein: 59-117
Range on HMM: 1-64/296
Sequence Identity: 37% (24 aa)

ELGRGAWGVVWVGQFR--GHPVAVKELH---EAIRSPLYLENIHREMSTMSQLRHPNLLQFIGA
|.|.|. | |  |  |  | ..|.|..|   .    | |. .. ||. .|  ||||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK541.AA DRK 61-131 41 1.8e-13 42.0 In-house 8-77 (258) Show / Hide 
Range on Protein: 61-131
Range on HMM: 8-77/258
Sequence Identity: 41% (30 aa)

GRGAWGVVWVGQFRGHPVAVKELHEAIRS-PLYLENIHREMSTMSQLRHPNLLQFIGAVLDHPSGNPMIITE
||| .| |. |  ||  |||| |          |   |||   |.||||||  ||.|. .  |.  . |..|
GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPD--ICICME
Kinase AqueK541.AA DRK 154-260 33 2.8e-13 41.39 In-house 98-197 (258) Show / Hide 
Range on Protein: 154-260
Range on HMM: 98-197/258
Sequence Identity: 33% (37 aa)

PVILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFGSAN----AANKAVTRLP-GAEPYTAPEALAQHIMSTDSKKEQTTKMDV
| ....| |.| |..||||    |||||  | | |     |  |. |..||| .        .  .. . |    |||| |.            | | ||
PLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLV----DEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRY--------TEKADV

FSYGVLLCEIIT
.|... | |..|
YSFAIVLWECVT
Kinase AqueK541.AA MLK 54-131 26 4.2e-12 38.39 In-house 1-90 (291) Show / Hide 
Range on Protein: 54-131
Range on HMM: 1-90/291
Sequence Identity: 26% (24 aa)

TLSKEELGRGAWGVVWVGQFRGHP-----VAVKELH-EAIRSPLY----LENIHREMSTMSQLRHPN----LLQFIGAVLDHPSGNPMIITE
 . .| .| |. |.|| |..|.       ||||. . ... .        ... .|    . |.|||      || |. |..|  .  |..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVME
Kinase AqueK541.AA LISK-DD1 59-117 36 7.4e-11 35.71 In-house 1-65 (290) Show / Hide 
Range on Protein: 59-117
Range on HMM: 1-65/290
Sequence Identity: 36% (24 aa)

ELGRGAWGVVWVGQFRGHPVAVKELHE----AIRSPLYLENIHREMSTMSQ---LRHPNLLQFIGA
| |.|. | |  |   | |||.|..|.    ... | |.  . || ..      .||||. ||||.
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPND-PDYWKFMQREIKMLKNLLNIRHPNIVQFIGI
Kinase AqueK541.AA LISK 243-260 61 3.7e-07 19.07 In-house 217-234 (296) Show / Hide 
Range on Protein: 243-260
Range on HMM: 217-234/296
Sequence Identity: 61% (11 aa)

TTKMDVFSYGVLLCEIIT
... ||||.|..||||||
DESCDVFSFGIVLCEIIT
Kinase AqueK541.AA LISK 161-205 42 7e-07 18.17 In-house 108-150 (296) Show / Hide 
Range on Protein: 161-205
Range on HMM: 108-150/296
Sequence Identity: 42% (19 aa)

RDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
.|.| |. |||     |||||  | |.|.  ...  |. |. |||
LDIACGMSYLHS--MNIIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK541.AA Dicty4 294-321 36 2e-06 17.36 In-house 248-277 (277) Show / Hide 
Range on Protein: 294-321
Range on HMM: 248-277/277
Sequence Identity: 36% (11 aa)

LHSLIIWCCKDDPLERPSMSQIIKQ--IDN
. .|| ||   ||  |||...||..   . 
WKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK541.AA Pkinase_Tyr 156-205 32 1.5e-05 19.43 Pfam 113-156 (270) Show / Hide 
Range on Protein: 156-205
Range on HMM: 113-156/270
Sequence Identity: 32% (16 aa)

ILSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
.|.. ...| |..||.  .  .||||.   |.|...   .. . ||.|||
LLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTE---NN-VVKICDFG
Kinase AqueK541.AA LISK-DD1 247-271 48 1.8e-05 16.03 In-house 213-237 (290) Show / Hide 
Range on Protein: 247-271
Range on HMM: 213-237/290
Sequence Identity: 48% (12 aa)

DVFSYGVLLCEIITCRFPDRDVFQN
||||.|..| |.|| . || .. |.
DVFSFGMVLLELITRKKPDKRMWQR
Kinase AqueK541.AA TKL-Unique 297-319 43 2.4e-05 15.01 In-house 268-290 (290) Show / Hide 
Range on Protein: 297-319
Range on HMM: 268-290/290
Sequence Identity: 43% (10 aa)

LIIWCCKDDPLERPSMSQIIKQI
||  |...|| .||| ..||. .
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK541.AA CZAK 243-267 48 3e-05 15.17 In-house 200-224 (279) Show / Hide 
Range on Protein: 243-267
Range on HMM: 200-224/279
Sequence Identity: 48% (12 aa)

TTKMDVFSYGVLLCEIITCRFPDRD
| | ||.|.| .| .||||. |  .
TEKVDVYSFGMILWCIITCDQPYQN
Kinase AqueK541.AA LISK-DD1 292-319 39 3.3e-05 15.04 In-house 263-290 (290) Show / Hide 
Range on Protein: 292-319
Range on HMM: 263-290/290
Sequence Identity: 39% (11 aa)

SLLHSLIIWCCKDDPLERPSMSQIIKQI
. . .|  |||| || .||| . |. ..
REFMDLCMWCCKYDPNNRPSFKEIVQTL
Kinase AqueK541.AA LISK 294-319 38 6.9e-05 11.59 In-house 271-296 (296) Show / Hide 
Range on Protein: 294-319
Range on HMM: 271-296/296
Sequence Identity: 38% (10 aa)

LHSLIIWCCKDDPLERPSMSQIIKQI
.. | ..||| || .||| . |....
FLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase AqueK541.AA DRK 297-321 32 0.00014 11.47 In-house 234-258 (258) Show / Hide 
Range on Protein: 297-321
Range on HMM: 234-258/258
Sequence Identity: 32% (8 aa)

LIIWCCKDDPLERPSMSQIIKQIDN
|.. |   ||  |||| .... .. 
LMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK541.AA MLK 296-319 37 0.000193 11.47 In-house 268-291 (291) Show / Hide 
Range on Protein: 296-319
Range on HMM: 268-291/291
Sequence Identity: 37% (9 aa)

SLIIWCCKDDPLERPSMSQIIKQI
.|.  | ..|| .|||..||... 
KLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK541.AA LISK-DD1 157-205 42 0.000609 10.42 In-house 126-172 (290) Show / Hide 
Range on Protein: 157-205
Range on HMM: 126-172/290
Sequence Identity: 42% (21 aa)

LSIMRDVAVGLNYLHCLPDPIIHRDVSSANVLLESKGDKKWKTKISDFG
..| .|.| .  |||     |||||  | | |.   || .|. |. |||
VKIALDIACAMAYLHSK--NIIHRDLKSKNILVDENGDSQWRIKVCDFG
Kinase AqueK541.AA Pkinase_Tyr 294-319 34 0.001325 12.83 Pfam 245-270 (270) Show / Hide 
Range on Protein: 294-319
Range on HMM: 245-270/270
Sequence Identity: 34% (9 aa)

LHSLIIWCCKDDPLERPSMSQIIKQI
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IYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK541.AA Pkinase_Tyr 224-264 38 0.022724 8.65 Pfam 181-214 (270) Show / Hide 
Range on Protein: 224-264
Range on HMM: 181-214/270
Sequence Identity: 38% (16 aa)

TAPEALAQHIMSTDSKKEQTTKMDVFSYGVLLCEIIT-CRFP
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MAPECINYGK--------FTTKSDVWSFGVLMWEIFTYGEQP
Kinase AqueK541.AA CZAK 297-319 43 0.153692 1.55 In-house 257-279 (279) Show / Hide 
Range on Protein: 297-319
Range on HMM: 257-279/279
Sequence Identity: 43% (10 aa)

LIIWCCKDDPLERPSMSQIIKQI
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LIEMCWNKNPDERPSFKQILQHL