Gene AqueK568 (A.queenslandica)

AqueK568

Species: A.queenslandica
Alias: AqueK568
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK568.AA Protein None 913 None Fasta, JSON
AqueK568.kin_dom Protein Kinase Domain None 240 None Fasta, JSON

Protein domain

Protein domains of AqueK568.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK568.AA Kelch_2 17-73 17 0.000182 21.1 Pfam 1-51 (51) Show / Hide 
Range on Protein: 17-73
Range on HMM: 1-51/51
Sequence Identity: 17% (10 aa)

ERREHSTVRVGDYLYMWGGVQPDLPEVHNNEKKKSMCSVMEVCHLRTSRWEQKPTTG
 |  |... .|. .|..||.        ..  . . .... .....| ||.  |  .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK568.AA Kelch_1 17-73 15 4.44226 4.05 Pfam 1-45 (45) Show / Hide 
Range on Protein: 17-73
Range on HMM: 1-45/45
Sequence Identity: 15% (9 aa)

ERREHSTVRVGDYLYMWGGVQPDLPEVHNNEKKKSMCSVMEVCHLRTSRWEQKPTTG
 |. |. . .....|  ||. .            .  .  |. ...| .|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK568.AA Kelch_1 78-125 18 1e-06 27.47 Pfam 1-45 (45) Show / Hide 
Range on Protein: 78-125
Range on HMM: 1-45/45
Sequence Identity: 18% (9 aa)

GVSSYAAAAIGREIFYFGGHCGHGGCLHNSLYSFNVDTSNWKKLSPTT
  ......... .|. .||..|      || ......|  |....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK568.AA Kelch_2 78-125 17 0.000595 19.14 Pfam 1-51 (51) Show / Hide 
Range on Protein: 78-125
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GVSSYAAAAIGREIFYFGGH---CGHGGCLHNSLYSFNVDTSNWKKLSPTT
. .. |.. .|  |. |||.    ....| ..... .. .|  |.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK568.AA Kelch_2 263-304 23 0.018951 13.43 Pfam 1-47 (51) Show / Hide 
Range on Protein: 263-304
Range on HMM: 1-47/51
Sequence Identity: 23% (12 aa)

ERRSHSSVLINTSSGPHLLVVGGV---------DTYDIWIFDINNKSWKQL
 | .|.|. .    |  ..|.||.         .. |||..| . ..|. .
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCV
Kelch_1 AqueK568.AA Kelch_1 274-304 17 0.138527 9.45 Pfam 8-41 (45) Show / Hide 
Range on Protein: 274-304
Range on HMM: 8-41/45
Sequence Identity: 17% (6 aa)

TSSGPHLLVVGGVD---TYDIWIFDINNKSWKQL
.. . .. |.||.|   . .....|  ...|...
CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRC
Kinase AqueK568.AA TKL 482-713 19 2.3e-47 163.66 In-house 1-364 (364) Show / Hide 
Range on Protein: 482-713
Range on HMM: 1-364/364
Sequence Identity: 19% (73 aa)

LGRGGWGEVRVAHFHG----------LEVAAKVLHETIISEYNV-------------------------SLFSREMNIASKIRHPNLLQFIGATTEGN--
.|.|| |||  ....|           .|| |.....  .| .                            . .|... |..||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELETGGLAYHATLSISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQPMGE-----------TWRAKV
            . | .|..   ||.  |       | .....||.|...||||  .|      ||.|||  |.|.|.   ..           .|..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGSANLQPLIG---------------------RTTNPGNPVYSAPEA--GNP--------------REHSPSMDVFSYGVLLLEMITQRIPLPEER--
.|.| .      |                     . |  |.| . |||.  |..              .| |...||.|.|..| |..| ..|  ..   
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VGLIDGIRR--------------------ASFRSIVQRCLIVEYRHRPTMNDIITEL
            .. .|  .|                     |.... |.|   . . ||....|. .|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK568.AA S_TKc 476-718 21 5.9e-29 103.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 476-718
Range on HMM: 1-231/231
Sequence Identity: 21% (56 aa)

RMTERILGRGGWGEVRVAHFHG--LEVAAKVLHETIISEYNVSLFSREMNIASKIRHPNLLQFIGATTEGNPIILTELMPT---SLRKELETGG------
    |..|.|. |.|. .. ..   .|| |...           . ||..| .| .|||. .....  ...  . .|....   .|.. ..  |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LAYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGETWRAKVSDYGSANLQPLIGRTTNPGNPVYSAPEAGNPREHSP-SMDVFSYGVLL
 .    . ..   ..|||.|.|  .   |.|||.  .|.||       . |..| |.| .      ||  | | | |||      ... . |. | |..|
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEMITQRIPLPEERVGLIDGIRRASFRSIVQRCLIVEYRHRPTMNDIIT----ELNDTLY
 ||.. . | | .   ... |.  ........|| .. ..|||  .. .      ..   
YEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK568.AA CZAK 479-671 32 6e-25 87.61 In-house 4-221 (279) Show / Hide 
Range on Protein: 479-671
Range on HMM: 4-221/279
Sequence Identity: 32% (71 aa)

ERILGRGGWGEVRVAHFHGLEVAAKVLHETIISEYNV----SLFSREMNIASKIRHPNLLQFIGATTEGN---PIILTELMP-TSLRKELETGGLAYHAT
..  |.|  |||. |   |  || | .|     .         | .|  | || .||| .||.|| .|..     | .| |   |||. | |    ||  
GQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL-TDHYFYHKQ

-----LSISLDVACALNYLHL-FKPHPILHRDVSSANVLLQPMGE----------TWRAKVSDYGSA---NLQPLIGRTTNPGNPVYSAPEAGNPREHSP
     ... .|.|   ||||  .|| |||||| || |.||                  .|..|.|       ||    |   |   . |||       ..
NPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQP-FEMTQTMGCLCWMAPECFKGENYTE

SMDVFSYGVLLLEMITQRIP
  ||.|.| .| ..|| . |
KVDVYSFGMILWCIITCDQP
Kinase AqueK568.AA MLK 476-671 23 7.3e-25 83.25 In-house 1-235 (291) Show / Hide 
Range on Protein: 476-671
Range on HMM: 1-235/291
Sequence Identity: 23% (55 aa)

RMTERILGRGGWGEVRVAHFHGLE-----VAAKVLHETIISEYNVS-----LFSREMNIASKIRHPN----LLQFIGATTE-GN-PIILTELMPT-SLRK
  .....| |. |.|  . ... .     || |  . .|. .  ..      | .| .......|||      || |. .. ..   |..| ..  ||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELETG---------------GLAYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQ----PMGETWRAKVSDYGSAN-LQPL-IGRTTNPGNPV
 | ..                   .  ....|..| ...|||  .|.|| |||  | |.|.     .|...  .|..| | .  ..     .. |.|.. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG-TLKICDFGTSRDWHQMCTNMMSNAGTYA

YSAPEA---GNPREHSPSMDVFSYGVLLLEMITQRIP
. |||.         | . ||.|.||.| ||.| ..|
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK568.AA Pkinase 476-713 19 3.5e-23 83.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 476-713
Range on HMM: 1-293/293
Sequence Identity: 19% (59 aa)

RMTERILGRGGWGEVRVAHFHGLE--VAAKVLH-ETIISEYNVSLFS-REMNIASKIRHPNLLQFIGAT-TEGNPIILTELMPT-----SLRKELE---T
  ..|..|.|. |.|. .| .| .  || |..  ... |. .....  .|  |  ...||| ......  ..... . .|...      .|   ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGL--AYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGET-WRAKVSDYGSAN---LQPLIGRTTNPGNPVYSAPEAGN-PREHSPSMDV
|..   ..   .. . ....|.|.|      |.|||. ..|.|.   |..  . |..| |.|    . .    ||  | | | |||  .  ....|. |.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSYGVLLLEMITQRIPLPEE-------RVGLIDGIRR-------------------------------ASFRSIVQRCLIVEYRHRPTMNDIITE--L
.|.|..| ||.. | | |..          .|. |..                                ...... .|| .    |||  .|     .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK568.AA TK 479-713 13 1e-22 72.28 In-house 4-486 (486) Show / Hide 
Range on Protein: 479-713
Range on HMM: 4-486/486
Sequence Identity: 13% (67 aa)

ERILGRGG---WGEVRVAHFHGL---------------------------EVAAKVLHETIISEYN-VSL--------------FSREMNIAS--KIRHP
.. ||.|    .|||. .  .|.                           .|| |.|.|.  .. .   .              . .|| . .  . .||
GKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHP

NLLQFIGATTEGN-------------PIILTELMP-TS----LRKELETGG-------------------------------------------------
|.....|. |.|              ..|..|.||  .    ||. | .                                                   
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

--------LAYHATLS-------------------ISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQ-PMGETWR-------AKVSDYGSAN---
        |  .  |.                   .....||.. |||  .         |||.   |.|.   .  .|        .|..|.| .    
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS

--LQPLIG------RTTNPGNPV-------------------------YSAPEAGN---------PREHSPSMDVFSYGVLLLEMIT--QRIPLP-----
  |   |.      |....| ..                         . |||. |          . ...  ||.|.|||. |. |  |  . .     
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQ

-----------------------------EERVGLI--DGIRR-------------ASFRSIVQRCLIVEYRHRPTMNDIITEL
                             ..|  .   ..                . .  . |.|   . ..|||. ..  .|
DVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK568.AA Dicty4 478-715 27 2.4e-21 68.13 In-house 3-277 (277) Show / Hide 
Range on Protein: 478-715
Range on HMM: 3-277/277
Sequence Identity: 27% (77 aa)

TERILGRGGWGEVRVAHFHGLEVAAKVL--HETIISEYNVSLFSREMNIASKIRHPNLLQFIGATT-----EGNPIILTELM-PTSLRKELET-------
.| ..|.|. |||  .   | ||| |.|  | .  .|.  . | .| .| .||||||...| || |      | . | ||.|  ..| . |         
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

-GGLAYHATLS---ISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGETWRAKVSDYGSAN-LQPLI----GRTTNPGNPVYSAPEAGNPREHSPSM
   | .   ..   . .|.|  .|.||   |  |.|||  |.| |   . . ||.||.| | .   .. .    . .|  | | . |||    ..   . 
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLL---VDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVFSYGVLLLEMITQRIPLP---EERVGLIDGIRR------------ASFRSIVQRCLIVEYRHRPTMNDIITE--LND
||.|.| .| |. |  .| .    . . ..... .            .|... .|.|.  .  |||... || .  |. 
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK568.AA TKL-Unique 478-671 26 6.3e-21 70.65 In-house 1-233 (290) Show / Hide 
Range on Protein: 478-671
Range on HMM: 1-233/290
Sequence Identity: 26% (61 aa)

TERILGRGGWGEVRVAHFHGLEVAAKVLH-ETIISEYNVSLFSREMNIASKIR-HPNLLQFIGATT-----EGNPIILTELMPT-SLRKELE--------
    .|.|| |.|  . ..| .|| |..| .  .|   .  |..| |. .|.. |||.....|...     ..| .| .| .|  ||.. |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---TGGLAYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPM--GETWRAKVSDYGSANLQPLIGRTTNP-----------GNPVYSAPEAGN
      | .   ... .|.| ...|||  .|  |.|||  | |.|.        |..|..| | . ..  | ..||            |.. ..|||  .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--REHSPSMDVFSYGVLLLEMITQRI------P
      | . ||.|.|. | |..|  |      |
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase AqueK568.AA Dicty5 497-671 28 1.1e-19 64.49 In-house 22-202 (260) Show / Hide 
Range on Protein: 497-671
Range on HMM: 22-202/260
Sequence Identity: 28% (54 aa)

GLEVAAKVLHETIISEYNVSLFSREMNIASKIR--HPNLLQFIGATTEGNPI--ILTELMPT-SLRKELETGGL------AYHATLSISLDVACALNYLH
|  || ||.       ..   | ||  | | .   |||.  . || .       ..||.    ||.  |           ||   |.. .|.| .. .||
GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLH

LFKPHPILHRDVSSANVLLQPMGETWRAKVSDYG-SANLQPLIGRTTNPGNPVYSAPEAGNPREHSPSMDVFSYGVLLLEMITQRIP
      | |||. | |.|.    | | .|. |.| | .     . |.. | . . |.|  | .      ||.|.|. | ||.|.  |
SMN---IIHRDLKSMNFLIT---ENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEP
Kinase AqueK568.AA STE 477-730 16 1.2e-19 66.18 In-house 1-359 (359) Show / Hide 
Range on Protein: 477-730
Range on HMM: 1-359/359
Sequence Identity: 16% (63 aa)

MTE-RILGRGGWGEVRVAHFH-----------------GLEVAAKVLH----ETIISE------------YNVSLFSREMNIASKIR--HPNLLQFIGAT
 .  ...|.|. |.|  |  |                 |  .| |...    .. . |             ..  . .|..| .| .  |||  ...|. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

T--------EGNPIILTELMP-TSLRKELE-TGGLA--------------YHATLSISLDVACA-LNYLHLFKPHPILHRDVSSANVLLQPMGETWRAKV
         ...  |  |.|.  ||.. .. ..|                 .    |  ..  . |.|||  .   | |||. .||.||        .| 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL--------VKL

SDYGSAN-LQPLIG-----------------RTTNPGNPVYSAPEAGNP------REHSPSMDVFSYGVLLLEMITQRIPL---PEERVGLIDGIRR---
.| | .  |.. .                  |.|  | | . |||  ..       ... . |. | | ...||.| . |.   .  |. .   .     
CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQ

----------------------------------------ASFRSIVQRCLIVEYRHRPTMNDIITELNDTLYYQPVKRSEHSTV
                                         .|.  ...||. ....||| .. . .             ||. .
QQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKS-------------EHPFI
Kinase AqueK568.AA DRK 475-619 36 8.7e-18 56.86 In-house 1-145 (258) Show / Hide 
Range on Protein: 475-619
Range on HMM: 1-145/258
Sequence Identity: 36% (54 aa)

IRMTERILGRGGWGEVRVAHFHGLEVAAKVLHETIIS-EYNVSLFSREMNIASKIRHPNLLQFIGATTE-GNPIILTELMPT-SLRKEL--ETGGLAYHA
|    || |||..|||      | .|| | |    |  |  .. | || |. .. ||||  ||.|. ..   . | .| ||  || . |  |   .    
IKIGNRI-GRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPL

TLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGETWRAKVSDYG
 ... .|.|  ..|||   |  |.|||  | | |     | |. ||.|.|
MKQMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLLVD---EHWQVKVADFG
Kinase AqueK568.AA Pkinase_Tyr 475-604 25 5.8e-15 51.3 Pfam 1-144 (270) Show / Hide 
Range on Protein: 475-604
Range on HMM: 1-144/270
Sequence Identity: 25% (38 aa)

IRMTERILGRGGWGEVRVAHFH------GLEVAAKVLHETIISEY--NVSLFSREMNIASKI-RHPNLLQFIGATT-EGNP---IILTELMPT-SLRKEL
|..  . ||.|  |||. .. .      ...|| |.| |.  .|     .... |..| ... .|||.....|. | .| |   .| .|.||  .|.. |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ETG-----GLAYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLL
 .       |  .  |......|....||.  .   . |||.   |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV
Kinase AqueK568.AA TyrKc 476-713 22 1.6e-14 12.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 476-713
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

RMTERILGRGGWGEVRVAHFHGLEVAAKVLHETIISEYNVSLFSREMNIASKI--RHPNLLQFIGATTE--------GNPIILTELMPT-SLRKELETGG
   ...||.|  |||. ..   ..|| |.|.|       .  | ||..| .|.  .|||.....|. |.        . . |..|.||  .|.. |   .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LAYHATLSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPMGETWRAKVSDYGSANLQPLI------GRTTNP-----GN---PV-YSAPEAGNPR
  |     ||.....||  .|||    ... |||    |.|.   .   ..|.|| | .            . .  .     |.   |.   |||. | .
PKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

EHSPSMDVFSYGVLLLEMITQRIPLPEE-----------RVGLIDGIRRASFRS---------------IVQRCLIVEYRHRPTMNDIITEL
. ..  ||.|.||.. |. |   . ...           .  . .| |.    .               | ..|   .   |||...|. ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK568.AA LISK 481-539 28 5.2e-13 38.41 In-house 1-64 (296) Show / Hide 
Range on Protein: 481-539
Range on HMM: 1-64/296
Sequence Identity: 28% (18 aa)

ILGRGGWGEV-RVAHF-HGLEVAAKVLH---ETIISEYNVSLFSREMNIASKIRHPNLLQFIGA
..|.|. |.| .. |.  | ..| | .|   .. . . .   . ||. .  ..|||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK568.AA LISK 571-619 42 1e-06 17.4 In-house 104-150 (296) Show / Hide 
Range on Protein: 571-619
Range on HMM: 104-150/296
Sequence Identity: 42% (21 aa)

LSISLDVACALNYLHLFKPHPILHRDVSSANVLLQPM-GETWRAKVSDYG
..|.||.||.. |||  .   |.|||  | |.|.     . ||.|| | |
VKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFG
Kinase AqueK568.AA LISK 652-673 50 2e-06 16.89 In-house 219-240 (296) Show / Hide 
Range on Protein: 652-673
Range on HMM: 219-240/296
Sequence Identity: 50% (11 aa)

SMDVFSYGVLLLEMITQRIPLP
| ||||.|..|.|.||.. . |
SCDVFSFGIVLCEIITRVKADP
Kinase AqueK568.AA TKL-Unique 687-713 29 0.015887 4.94 In-house 264-290 (290) Show / Hide 
Range on Protein: 687-713
Range on HMM: 264-290/290
Sequence Identity: 29% (8 aa)

SFRSIVQRCLIVEYRHRPTMNDIITEL
..| . |.|   .   ||. ..||..|
EYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK568.AA DRK 654-671 38 0.023786 3.81 In-house 184-201 (258) Show / Hide 
Range on Protein: 654-671
Range on HMM: 184-201/258
Sequence Identity: 38% (7 aa)

DVFSYGVLLLEMITQRIP
||.|... | |..|  .|
DVYSFAIVLWECVTRQDP
Kinase AqueK568.AA DRK 693-715 26 0.203018 0.61 In-house 236-258 (258) Show / Hide 
Range on Protein: 693-715
Range on HMM: 236-258/258
Sequence Identity: 26% (6 aa)

QRCLIVEYRHRPTMNDIITELND
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NDCWNEDPQHRPSMQECLERLEA
Kinase AqueK568.AA MLK 703-713 36 0.313517 0.18 In-house 281-291 (291) Show / Hide 
Range on Protein: 703-713
Range on HMM: 281-291/291
Sequence Identity: 36% (4 aa)

RPTMNDIITEL
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RPSFRQIVQHL
Kinase AqueK568.AA Pkinase_Tyr 654-667 57 1.002566 3.08 Pfam 196-209 (270) Show / Hide 
Range on Protein: 654-667
Range on HMM: 196-209/270
Sequence Identity: 57% (8 aa)

DVFSYGVLLLEMIT
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DVWSFGVLMWEIFT
Kinase AqueK568.AA Pkinase_Tyr 702-713 41 3.408398 1.28 Pfam 259-270 (270) Show / Hide 
Range on Protein: 702-713
Range on HMM: 259-270/270
Sequence Identity: 41% (5 aa)

HRPTMNDIITEL
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DRPTFSEIHEQL