Gene AqueK572 (A.queenslandica)

AqueK572

Species: A.queenslandica
Alias: AqueK572
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-B

Sequence

Name Sequence Type Origin Length Description Download
AqueK572.AA Protein None 798 None Fasta, JSON
AqueK572.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of AqueK572.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK572.AA Kelch_2 21-77 17 0.006102 15.3 Pfam 1-51 (51) Show / Hide 
Range on Protein: 21-77
Range on HMM: 1-51/51
Sequence Identity: 17% (10 aa)

ERSGHSTLKVGDYLYMWGGIQPDLPTAHNNEKKKAMSTLIEVYHLPTGAWEQKATIG
 |..|..  .|. .|..||.        ..  .   |  | .... |  |.  . ..
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK572.AA Kelch_1 21-77 17 0.071491 10.48 Pfam 1-45 (45) Show / Hide 
Range on Protein: 21-77
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

ERSGHSTLKVGDYLYMWGGIQPDLPTAHNNEKKKAMSTLIEVYHLPTGAWEQKATIG
 |.||.   .....|  ||  .              .  .|.|.. |. |.. .. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK572.AA Kelch_1 82-129 20 8.7e-07 28.1 Pfam 1-45 (45) Show / Hide 
Range on Protein: 82-129
Range on HMM: 1-45/45
Sequence Identity: 20% (10 aa)

GISGYASAVIGNEIFYYGGYCNHDDCYHNSLYSFNVDTLTWKLLSSTT
  .|....|....|.  ||...    | || ......| .|. ... .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK572.AA Kelch_2 82-129 23 0.000411 19.75 Pfam 1-51 (51) Show / Hide 
Range on Protein: 82-129
Range on HMM: 1-51/51
Sequence Identity: 23% (12 aa)

GISGYASAVIGNEIFYYGGY---CNHDDCYHNSLYSFNVDTLTWKLLSSTT
. .. ||.|.|. |. .|||     ..||...... .. .| .|. ..   
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK572.AA Kelch_1 185-200 37 35.087662 0.83 Pfam 23-38 (45) Show / Hide 
Range on Protein: 185-200
Range on HMM: 23-38/45
Sequence Identity: 37% (6 aa)

QHTNEIYYYKLSTDQW
| .| ...| ..|.||
QYLNSVECYDPETNQW
Kelch_2 AqueK572.AA Kelch_2 267-302 27 34.300865 1.05 Pfam 1-35 (51) Show / Hide 
Range on Protein: 267-302
Range on HMM: 1-35/51
Sequence Identity: 27% (11 aa)

ARWGHSSVLIHDESSEPYLLVVGGY----PSKDCWLFNIN
 | .|.|. .     .  ..|.|||    . .|||.. |.
PRYCHASCVP-----GGKIYVFGGYCRHTHNNDCWSMDIW
Kinase AqueK572.AA TKL 558-793 19 8.7e-48 165.07 In-house 1-364 (364) Show / Hide 
Range on Protein: 558-793
Range on HMM: 1-364/364
Sequence Identity: 19% (73 aa)

LGRGGWGEVRVALFQG----------LKVAAKVLHETIISEYNL-------------------------SIFSREMEIAAKVRHPNLLQFIGATKEGN--
.|.|| |||  . ..|            || |.....  .| ..                           . .|. .  . ||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELEGGEGIPYPTVLSISLDVACALNYLHLCK------PPILHRDVSSANVLLQSMGG-------GYGSGWRAK
            . | .|..   ||.  |        .  ....||.|...|||| ..      |||.|||  |.|.|. . .           . |..|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LSDYGSANLQPLIGN--------------------TSNPG-NPVYSAPEAANPI----------------DHSPAMDAYSYGVLLLEMVTRRIPLPHER-
..|.| .      ||                    |.... .| . |||. .                  . |...| ||.|..| |..||..|  ..  
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

-------------IGLIDNVRKVPFK--------------------SLIQRCVVTDPAKRLKMSEIIIEL
             .. .|. .. | .                    .|.|.|  .|| ||. ..||. .|
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc AqueK572.AA S_TKc 552-797 21 1.2e-32 115.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 552-797
Range on HMM: 1-231/231
Sequence Identity: 21% (56 aa)

IMTEKVLGRGGWGEVRVALFQG--LKVAAKVLHETIISEYNLSIFSREMEIAAKVRHPNLLQFIGATKEGNPIILTELMPT---SLRKELEGGEG-----
    ...|.|. |.|. .   .   .|| |...           . ||..|  | .|||. .....  ...  . .|....   .|.. ..   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-IPYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWRAKLSDYGSANLQPLIGNTSNPGNPVYSAPEAANPIDHSP-AMDAYSYG
 .|  .. ..   ..|||.|.|     |.|||.  .|.|| .         . |..| |.| .      |.  | | | |||      ... . | .| |
PFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLLEMVTRRIPLPHERIGLIDNVRKVPFKSLIQRCVVTDPAKRLKMSEIII-----ELNDML
..| ||.... | | .   ......  ..|..|..| . ||.||.   |.        .   .
CILYEMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK572.AA TK 552-793 13 1.7e-27 88.62 In-house 1-486 (486) Show / Hide 
Range on Protein: 552-793
Range on HMM: 1-486/486
Sequence Identity: 13% (68 aa)

IMTEKVLGRGG---WGEVRVALFQGL---------------------------KVAAKVLH---ETIISEYNLSIFS---------REMEIAAKVR----
|  .|.||.|    .|||. .. .|.                           .|| |.|.   ..   |  . ..          .|.|.... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLLQFIG-ATKEGN------------PIILTELMP-TS----LRKELEGGEG---------------------------------------------
 |||.....|  |....            ..|..|.||  .    ||. |    .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------IPYPTVLSISLDVACALNYLHLCKP----PILHRDVSSANVLLQSMGGG----YGSGWRAKLSDYGSAN
                               .. .. | .....||.. ||| ..      . |||.   |.|. . .       |.|  .|..|.| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LQPLIGN------TSNPGNPV-------------------------YSAPEAAN---------PIDHSPAMDAYSYGVLLLEMVT--RRIPLP--
     |   |..      .|..| ..                         . |||. |            .... | .|.|||. |..|  .  . .  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------------------------------HERIGLI--DNVRK-------------VPFKSLIQRCVVTDPAKRLKMSEIIIEL
                                 .|  .   ..                  .  |.|.|   ||..|  .|..  .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK572.AA MLK 552-751 24 4.9e-27 90.9 In-house 1-235 (291) Show / Hide 
Range on Protein: 552-751
Range on HMM: 1-235/291
Sequence Identity: 24% (59 aa)

IMTEKVLGRGGWGEVRVALFQGLK-----VAAKVLHETIISEYNLS-----IFSREMEIAAKVRHPN----LLQFIGA-TKEGN-PIILTELMPT-SLRK
| .....| |. |.|  . ...       || |  . .|. .   .      | .| .......|||      || |. .....   |..| ..  ||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELEGGEG--------------IPYPTVLSISLDVACALNYLHLCKP-PILHRDVSSANVLLQS----MGGGYGSGWRAKLSDYGSAN-LQPL-IGNTSNP
 | |...              ..   .....|..| ...|||  .| || |||  | |.|.      |..|      .| .| | .  ..      .||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHG-----TLKICDFGTSRDWHQMCTNMMSNA

GNPVYSAPEA---ANPIDHSPAMDAYSYGVLLLEMVTRRIP
|.. . |||.   .     | . | .|.||.| ||.||..|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK572.AA Pkinase 552-784 19 8e-24 85.32 Pfam 1-282 (293) Show / Hide 
Range on Protein: 552-784
Range on HMM: 1-282/293
Sequence Identity: 19% (55 aa)

IMTEKVLGRGGWGEVRVALFQGLK--VAAKVLHETIISEYNLSIFSR--EMEIAAKVRHPNLLQFIGATK-EGNPIILTELMPT-----SLRKELE--GG
. .....|.|. |.|. .  .|    || |..    ...  . .  |  | .| ....||| ......   .... . .|...      .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EGI--PYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWRAKLSDYGSAN---LQPLIGNTSNPGNPVYSAPEAAN-PIDHSPAM
 ..  .. .. .. . ....|.|.| .   |.|||. ..|.|.    |  ..  . |..| |.|    . .   .|.  | | | |||  .   ...|. 
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILID-NNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DAYSYGVLLLEMVTRRIPLPHE-------RIGLIDNVRK-------------------------------VPFKSLIQRCVVTDPAKRL
| .|.|..| ||...| | |..        . .|.....                                ..|..| .|   ||.||.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase AqueK572.AA TKL-Unique 554-751 25 7.1e-23 77.62 In-house 1-233 (290) Show / Hide 
Range on Protein: 554-751
Range on HMM: 1-233/290
Sequence Identity: 25% (60 aa)

TEKVLGRGGWGEVRVALFQGLKVAAKVLH-ETIISEYNLSIFSREMEIAAKVR-HPNLLQFIGATK-----EGNPIILTELMPT-SLRKELE--------
  ...|.|| |.|  . . | .|| |..| .  .|   .  |..|  .  | . |||.....|...     ..| .| .| .|  ||.. |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--GGEGIPYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSG-----WRAKLSDYGSANLQPLI--GNTSNP---------GNPVYS
      ...  .... .|.| ...||| |.|||.|||  | |.|.        ..     |..|..| | . ..  |  ......         |.. ..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVD-------NNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

APEAANP--IDHSPAMDAYSYGVLLLEMVTRRI------P
|||  .    . |   | ||.|. | |..|| |      |
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase AqueK572.AA Dicty4 552-679 33 3.8e-22 70.79 In-house 1-146 (277) Show / Hide 
Range on Protein: 552-679
Range on HMM: 1-146/277
Sequence Identity: 33% (49 aa)

IMTEKVLGRGGWGEVRVALFQGLKVAAKVL--HETIISEYNLSIFSREMEIAAKVRHPNLLQFIGA-T----KEGNPIILTELM-PTSLRKELEG-----
| .|. .|.|. |||  .   | .|| |.|  | .  .|. |. | .| .| .| ||||...| || |    . | . | ||.|  ..| . |       
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

GEGIPYP--TVLS---ISLDVACALNYLHLCKPPILHRDVSSANVL
 . |. .  ....   . .|.|  .|.|| | | |.|||  |.| |
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLL
Kinase AqueK572.AA CZAK 552-682 34 7e-20 68.98 In-house 1-144 (279) Show / Hide 
Range on Protein: 552-682
Range on HMM: 1-144/279
Sequence Identity: 34% (49 aa)

IMTEKVLGRGGWGEVRVALFQGLKVAAKVLH----ETIISEYNLSIFSREMEIAAKVRHPNLLQFIGATKEGN---PIILTELMP-TSLRKELEGGEGIP
   ... |.|  |||. |   |  || | .|     .  .   . .| .|  |  | .||| .||.||  |..     | .| |   |||. |       
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

YP---TVLSISLDVACALNYLHL-CKP-PILHRDVSSANVLLQS
 .     ... .|.|   ||||   || |||||| || |.|| .
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDH
Kinase AqueK572.AA LRRK 552-751 22 2.8e-18 61.24 In-house 1-282 (351) Show / Hide 
Range on Protein: 552-751
Range on HMM: 1-282/351
Sequence Identity: 22% (63 aa)

IMTEKVLGRGGWG-EVRVALFQG----------------------------LKVAAKVLHET-----------------------------IISEYNLSI
.. |. .|||| | .|  | ..|                             .||.|... .                             ...|  . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FS---REMEIAAKVRHPNLLQFIGATKEGNPIIL-TELMPT-SLRKELE---GGE------GIPYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVL
|.   .|. |  . .|||... .| .   .|... .|..|  .| . |.     .       |.  ..| |.|..| ...||| ..|||.|||  | |.|
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

LQSMGGGYGSG-----WRAKLSDYGSAN----LQPLIGNTSNPGNPVYSAPEAAN---PIDHSPAMDAYSYGVLLLEMVTRR-IP
|.|.  .. ..       ||..|.|       ... . ...  |||.. |||  .    .  .   | ||.|..| | .||. .|
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV-GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase AqueK572.AA Pkinase_Tyr 552-699 24 1.9e-17 59.73 Pfam 1-156 (270) Show / Hide 
Range on Protein: 552-699
Range on HMM: 1-156/270
Sequence Identity: 24% (40 aa)

IMTEKVLGRGGWGEVRVALFQ------GLKVAAKVLHETIISEY--NLSIFSREMEIAAKV-RHPNLLQFIGATK-EGNP---IILTELMPT-SLRKELE
|   |.||.|  |||. .         ...|| |.| |.  .|     . .. |..|  .  .|||.....|.   .| |   .| .|.||  .|.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

G----GEGIPYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWRAKLSDYG
     .. .. .. |......|....||.  .  . |||.   |.|. .      ..  .| .| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTE------NN-VVKICDFG
Kinase AqueK572.AA Ciliate-E2 552-790 14 1.1e-16 53.74 In-house 1-360 (365) Show / Hide 
Range on Protein: 552-790
Range on HMM: 1-360/365
Sequence Identity: 14% (55 aa)

IMTEKVLGRGGWGEVRVA------------LFQGLK---------VAAKVLHETIISEYNLSIFSREMEIAAKVR----------------HPNLLQFIG
.   |..|.|. | |. .            ...  |         |..|     |...... ....|  |  ...                |||..... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

ATK---EGNPIILTELMPT-SLRK-----ELEGGEGIP------YPTVLSISLDVAC---------------ALNYLHLCKPPILHRDVSSANVLLQSMG
. .   . |  . .|.    .|..      .  .. |.         .. |.  ..                ||.|||  .. |.|||    |.|.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF----

GGYGSGWRAKLSDYGSANLQPLI----------GNTSNPG------------------------NPVYSAPEAAN--PID-------HSPAMDAYSYGVL
         |..| | .  .             ..  . .                        .| | |||  |  ..|       .. . | .| ||.
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

LLEMVTRRIPLPHERIGLIDNVRKVPFK----------------------------SLIQR----CVVTDPAKRLK-MSEII
| ||.. . |        ...  . ...                             ||..    . . || ||.  ...|.
LYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase AqueK572.AA DRK 552-699 33 2.8e-16 51.65 In-house 1-145 (258) Show / Hide 
Range on Protein: 552-699
Range on HMM: 1-145/258
Sequence Identity: 33% (51 aa)

IMTEKVLGRGGWGEVRVALFQGLKVAAKVLHETIIS-EYNLSIFSREMEIAAKVRHPNLLQFIGA-TKEGNPIILTELMPT-SLRKELEGGE-GIPYPTV
|      |||..|||      | .|| | |    |  |  |. | || ..  . ||||  ||.|. .    . | .| ||  || . |      .  | .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWRAKLSDYG
... .|.|  ..||| | | |.|||  | | |           |. | .|.|
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEH-------WQVKVADFG
Kinase AqueK572.AA STE 553-788 17 2.8e-16 54.08 In-house 1-350 (359) Show / Hide 
Range on Protein: 553-788
Range on HMM: 1-350/359
Sequence Identity: 17% (64 aa)

MTE-KVLGRGGWGEVRVALFQ-----------------GLKVAAKVLH----ETIISE------------YNLSIFSREMEIAAKVR--HPNLLQFIGAT
 .  ...|.|. |.|  |.                   |  .| |...    .. . |             ..  . .|..|  | .  |||  ...|. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

K--------EGNPIILTELMP-TSLRKELE---GGEG-----------IPYPTVLSISLDVACA-LNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWR
         ...  |  |.|.  ||.. ..   |  .           .| . .  |  ..  . |.|||  .  | |||. .||.||            
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------------

AKLSDYGSAN-LQPLIG----------------NT-SNPGNPVYSAPEAANP------IDHSPAMDAYSYGVLLLEMVTRRIPL---PHE----RIGLI-
.||.| | .  |.. .                 .. .  | | . |||  ..       ...   | .| | ...||.| . |.   ..     .|    
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNY

-------------DNVRKVP-------------------------FKSLIQRCVVTDPAKRLKMSE
             ..  . |                         ||  |..| . || || . |.
HMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase AqueK572.AA TyrKc 552-793 21 2e-14 10.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 552-793
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

IMTEKVLGRGGWGEVRVALFQGLKVAAKVLHETIISEYNLSIFSREMEIAAKV--RHPNLLQFIGATKE--------GNPIILTELMPT-SLRKELEGGE
|  .|.||.|  |||. .    ..|| |.|.|       .  | ||..|  |.  .|||.....|.  .        . . |..|.||  .|.. |   .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

G-IPYPTVLSISLDVACALNYLHLCKPPILHRDVSSANVLLQSMGGGYGSGWRAKLSDYGSANLQPLI-------GNTSN----PGN---PV-YSAPEAA
. .. .. ||.....||  .|||    .. |||    |.|. . .       ..| || | .                .      |.   |.   |||. 
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

NPIDH--SPAMDAYSYGVLLLEMVTRRIPLPHE-------------------RIGLIDN--------VRKVPFKSLIQRCVVTDPAKRLKMSEIIIEL
   ..  ... | .|.||.. |. |.  . . .                   |    .|          .  .. ....|   ||..|  .|||. ..
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK572.AA MLK 767-793 33 9e-06 16.17 In-house 265-291 (291) Show / Hide 
Range on Protein: 767-793
Range on HMM: 265-291/291
Sequence Identity: 33% (9 aa)

PFKSLIQRCVVTDPAKRLKMSEIIIEL
..|.|...|  .||.|| ....|. .|
HWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK572.AA Dicty4 767-795 38 0.000407 9.82 In-house 247-277 (277) Show / Hide 
Range on Protein: 767-795
Range on HMM: 247-277/277
Sequence Identity: 38% (12 aa)

PFKSLIQRCVVTDPAKRLKMSEIIIE--LND
..|.|||.|  .|| .|  ..||| .  |. 
SWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK572.AA DRK 734-751 50 0.00304 6.88 In-house 184-201 (258) Show / Hide 
Range on Protein: 734-751
Range on HMM: 184-201/258
Sequence Identity: 50% (9 aa)

DAYSYGVLLLEMVTRRIP
| ||... | |.||| .|
DVYSFAIVLWECVTRQDP
Kinase AqueK572.AA DRK 767-795 27 0.013916 4.61 In-house 230-258 (258) Show / Hide 
Range on Protein: 767-795
Range on HMM: 230-258/258
Sequence Identity: 27% (8 aa)

PFKSLIQRCVVTDPAKRLKMSEIIIELND
..  |...|  .||  |  | |..  |  
KYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK572.AA LRRK 768-795 39 0.032868 3.6 In-house 324-351 (351) Show / Hide 
Range on Protein: 768-795
Range on HMM: 324-351/351
Sequence Identity: 39% (11 aa)

FKSLIQRCVVTDPAKRLKMSEIIIELND
...||| |  .|| || ..|.|.  | .
YQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK572.AA Dicty4 734-751 50 0.03374 3.33 In-house 199-216 (277) Show / Hide 
Range on Protein: 734-751
Range on HMM: 199-216/277
Sequence Identity: 50% (9 aa)

DAYSYGVLLLEMVTRRIP
| ||.| .| |..|| .|
DVYSFGIVLWEILTRQEP
Kinase AqueK572.AA CZAK 718-751 29 0.101033 2.22 In-house 188-221 (279) Show / Hide 
Range on Protein: 718-751
Range on HMM: 188-221/279
Sequence Identity: 29% (10 aa)

YSAPEAANPIDHSPAMDAYSYGVLLLEMVTRRIP
. |||       ..  | ||.| .| ...| . |
WMAPECFKGENYTEKVDVYSFGMILWCIITCDQP
Kinase AqueK572.AA TKL-Unique 768-793 42 0.226245 0.82 In-house 265-290 (290) Show / Hide 
Range on Protein: 768-793
Range on HMM: 265-290/290
Sequence Identity: 42% (11 aa)

FKSLIQRCVVTDPAKRLKMSEIIIEL
.. |||.|   || .|   .||| .|
YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK572.AA Pkinase_Tyr 770-793 37 3.64815 1.18 Pfam 247-270 (270) Show / Hide 
Range on Protein: 770-793
Range on HMM: 247-270/270
Sequence Identity: 37% (9 aa)

SLIQRCVVTDPAKRLKMSEIIIEL
.|...|   ||..|  .|||. .|
DLMKQCWHYDPEDRPTFSEIHEQL