Gene AqueK614 (A.queenslandica)

AqueK614

Species: A.queenslandica
Alias: AqueK614
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK614.AA Protein None 768 None Fasta, JSON
AqueK614.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK614.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK614.AA TKL 527-763 20 3e-46 159.99 In-house 1-364 (364) Show / Hide 
Range on Protein: 527-763
Range on HMM: 1-364/364
Sequence Identity: 20% (74 aa)

LGRGSYAVVKVGIFRG----------LRVAVKSLHTIIISDFNL-------------------------ALFSREMSIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ...   . |..                           . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELM-STSLNQELRRNRLTNQQILSIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNVLLKPCTGP---------AGYEAKV
          |.. | .|..   ||   |       .|....|.|.|.|.||||  .|      ||||||  |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKLVQVDS--------------------TGTIMPGNVAYAAPEAPIPD----------------QHSPAMDVYSYSVLLMEMNL----YS-PPEM
.|.|... .. ..                    |     |. .. |||.   .                . |...||||. ..| |.      |. .|.|
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------TTAEREVQSGSV---------------SWSDMKSLIQRGLNASPRARPTMAQVIESL
              .  . .   .                . .||.|.|.  .. |..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK614.AA MLK 521-713 26 4.2e-33 112.21 In-house 1-229 (291) Show / Hide 
Range on Protein: 521-713
Range on HMM: 1-229/291
Sequence Identity: 26% (61 aa)

TLTKEELGRGSYAVVKVGIFRGLR-----VAVKSLHTIIISDFNLA-----LFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELMST-SLNQ
 ...| .| ||. .|  | .|. .     ||||  .. |. |   .      | .|  ......|||     .|| |. .. ..  .|..| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELRRNR---------------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKP-CTGPAGYEAKVADYGTAKLVQVD-STGTIMPGNVAY
 |. .|                . ......| ..| |..|||  .|.||||||  |.|.|.   |   ..  .|..| ||.. ..   .. . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAP---IPDQHSPAMDVYSYSVLLMEM
 |||.      .. | . ||.|. |.| ||
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK614.AA TK 521-713 14 8.9e-30 96.4 In-house 1-387 (486) Show / Hide 
Range on Protein: 521-713
Range on HMM: 1-387/486
Sequence Identity: 14% (58 aa)

TLTKEELGRGSYA---VVKVGIFRGL---------------------------RVAVKSLH---TIIISDFNLALFS---------REMSIASRVR----
    ..||.| .    .|  |. ||.                           .|||| |.   .    .| .. .          .|.....  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVQFIG-ATKVGN------------PLILTELMS-TS----LNQELRRNR----------------------------------------------
 |||.|...|  |....            ..|..|.|.  .    | . ||..|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNQQILSIAQDVALGLNYLHLFKP---QPIIHRDVSSPNVLLKPCTG------PAGYEAKVADYG---
                               || .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKLVQVDSTGTIMPGN---------------------------VAYAAPEAPI---------PDQHSPAMDVYSYSVLLMEM
      |. .. |.  . . .                            . . |||.              .... ||.|. ||. |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase AqueK614.AA TKL-Unique 523-713 28 3.3e-29 100.22 In-house 1-221 (290) Show / Hide 
Range on Protein: 523-713
Range on HMM: 1-221/290
Sequence Identity: 28% (63 aa)

TKEELGRGSYAVVKVGIFRGLRVAVKSLHTIIISDFNLA---LFSREMSIASRVR-HPNLVQFIGATK---VGNP--LILTELMST-SLNQELR------
  . .|.|.|..|. |..||  ||.|..|    .|...     |..| .. .. . |||.|...|...   | .|   | .| ..  ||.  |       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----RNRLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTIM----------PGNVAYAAPEA
      . |..||....|.|.|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|.   ....|.            |.  ..||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

PIP--DQHSPAMDVYSYSVLLMEM
     .| |   ||||... | |.
LRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK614.AA CZAK 522-713 29 6.8e-27 94.77 In-house 1-215 (279) Show / Hide 
Range on Protein: 522-713
Range on HMM: 1-215/279
Sequence Identity: 29% (63 aa)

LTKE-ELGRGSYAVVKVGIFRGLRVAVKSLHTIIISDFNL----ALFSREMSIASRVRHPNLVQFIGATKVGN---PLILTELMS-TSLNQELR-RNRLT
|. . . |.| .  |. .  ||  ||.| .| .   .         | .| || |  .||| |||.||   ..     | .| |   || . |  .  . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

NQ---QILSIAQDVALGLNYLHL-FKPQPIIHRDVSSPNVLLKPCTG--------PAGYEAKVADYGTAKLVQVDSTG-TIMPGNVAYAAPEAPIPDQHS
 |     ...| |.| | ||||  .|| ||.||| || |.||                  .|..|.|  ..     .  |   | ... |||  . .  .
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

PAMDVYSYSVLLMEM
.  ||||.  .| ..
EKVDVYSFGMILWCI
Kinase AqueK614.AA S_TKc 521-764 18 1.2e-25 92.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 521-764
Range on HMM: 1-231/231
Sequence Identity: 18% (49 aa)

TLTKEELGRGSYAVVKVGIFRG--LRVAVKSLHTIIISDFNLALFSREMSIASRVRHPNLVQFIGATKVGNPLILTELMST---SLNQELRRNR------
    ...|.|....|. .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTIMPGNVAYAAPEAPIPDQHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . |   | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEMNL----YSPPEMTTAEREVQSGSVSWSDMKSLIQRGLNASPRARPTMAQVIE--------SLK
..| ||      ..  .| .  . .       ...|..|.. |.  |. |||  .. .           
CILYEMLCGYPPFP--QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK614.AA Dicty4 523-713 29 2.5e-23 74.78 In-house 3-210 (277) Show / Hide 
Range on Protein: 523-713
Range on HMM: 3-210/277
Sequence Identity: 29% (63 aa)

TKEELGRGSYAVVKVGIFRGLRVAVKSL--HTIIISDFNLALFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELM-STSLNQELRR------N
. ...|.||.. |  |. ||  |||| |  | .  . . |  | .| .| .  ||||...| || |    . | ..| ||.| ...|   |.        
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

RLTNQ--QILS---IAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTI----MPGNVAYAAPEAPIPDQHSP
. . .   |..   .| |.|.|.|.||   |  |||||  | | |       . . .||.| | ... . ... .     . | ... |||    .    
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

AMDVYSYSVLLMEM
. ||||.. .| |.
KADVYSFGIVLWEI
Kinase AqueK614.AA STE 522-690 17 1.2e-21 73.25 In-house 1-232 (359) Show / Hide 
Range on Protein: 522-690
Range on HMM: 1-232/359
Sequence Identity: 17% (43 aa)

LTK-EELGRGSYAVVKVGIFR-----------------GLRVAVKSLH---------------TIIISDFNLALFSREMSIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELMS-TSLNQELRRN---------------RLTNQQILSIAQDVALG-LNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAK
..        .  |  |.|.  || . ....               |.  .||  |....  | |.|||  .   |||||. . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLVQ-----------------VDSTGTIMPGNVAYAAPE
 .| |... ..                  ..  . . |   . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE
Pkinase_Tyr AqueK614.AA Pkinase_Tyr 520-713 25 1.3e-20 70.48 Pfam 1-207 (270) Show / Hide 
Range on Protein: 520-713
Range on HMM: 1-207/270
Sequence Identity: 25% (56 aa)

VTLTKEELGRGSYAVVKVGIFR------GLRVAVKSLHTIIISDFN--LALFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELMST-SLNQEL
.|.  ..||.|.. .|. |. .      .. ||||.|     .. .  .. | ||..| .   .|||.|...|.    | |   .| .|.|   .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RRN-----RLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLV-----Q-VDSTGTIMPGNVAYAAPEAPIP
|..     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| | |...       . ..|. .|  .   |||.   
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLP--IKWMAPECINY

DQHSPAMDVYSYSVLLMEM
   . . ||.|. ||. |.
GKFTTKSDVWSFGVLMWEI
Kinase AqueK614.AA LRRK 521-690 23 1.8e-20 69.08 In-house 1-249 (351) Show / Hide 
Range on Protein: 521-690
Range on HMM: 1-249/351
Sequence Identity: 23% (58 aa)

TLTKEELGRGSYA-VVKVGIFRG----------------------------LRVAVKSLHTI------------------------------IISDF--N
    |..|||... .|  ...||                              ||.|.....                              ...|.  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LALFSREMSIASRVRHPNLVQFIGATKVGNPLIL-TELMST-SLNQELR---RNR-------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNV
. .| .|..| |. .|||.|. .| .   .||.. .|...  .|.. |.   ...       .. . .| || ..| |..||| ..| ||||||  |||.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLKPCTGP-------AGYEAKVADYGTAKLVQVDSTG--TIMPGNVAYAAPE
||.  . .       | . ||.||.|.  . |.. .|    . ||  . |||
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPE
Kinase AqueK614.AA TK-Unique 574-713 22 7e-19 61.84 In-house 62-232 (294) Show / Hide 
Range on Protein: 574-713
Range on HMM: 62-232/294
Sequence Identity: 22% (39 aa)

RHPNLVQFIGATK-VG-NPLILTELMSTS-LNQELRRNR---------------------------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVS
.|||.||..|..   . ...|. | .. . |   ||..|                           .. .. ...| ..| |..||.   .. |.|||..
DHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLC

SPNVLLKPCTGPAGYEAKVADYGTAKLVQ----VDSTGTIMPGNVAYAAPEAPI--PDQH-SPAMDVYSYSVLLMEM
. ||||       ....|..|.| |. |.    ......  .  ... |||..     .. ..  ||.|. ||. |.
ARNVLLTE-----DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEI
Kinase AqueK614.AA Dicty4-Unclassified 524-713 25 1.5e-17 56.63 In-house 4-201 (263) Show / Hide 
Range on Protein: 524-713
Range on HMM: 4-201/263
Sequence Identity: 25% (54 aa)

KEELGRGSYAVVKVGIFRGLRVAVKSLHTIIISDFN---LALFSREMSIASRVRHPNLVQFIGATKVGNP-------LILTELMSTSLNQELRR------
  ..|.|  . |  |. .|  |||| .     . |    .  | .|  |   . |||||.  |.    ||        | .|.|      |.        
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFK-FREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

-NRLTNQQ--ILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTIMPGNVAYAAPEAPIPDQHSPAMDVY
   .      |. .| |.| |. .||      .||||. | |.|.        . .|.|| | .  .    . |   | ..  .||         . |||
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVY

SYSVLLMEM
|| ..| |.
SYAMMLYEL
Kinase AqueK614.AA TyrKc 521-763 20 1.7e-17 60.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 521-763
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

TLTKEELGRGSYAVVKVGIFRGLRVAVKSLHTIIISDFNLALFSREMSIASRV--RHPNLVQFIGATKV--------GNPLILTELMST-SLNQELRRNR
   ...||.| . .|  |. . . ||||.|.        .. | ||..| ...  .|||.|...|.           . ..|..|.|.  .|.. ||..|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVD-------STGTI-----MP--GNVAYAAPEAPI
  |.... ||.. ..| | .|||     ..||||    |.|..         .|..| | .. .  |       .. .            .   |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLLMEM-----NLYSP-----PEMTTAEREVQSG------SV--------SWSDMKSLIQRGLNASPRARPTMAQVIESL
    ... ||.|. |.. |.       |.       . . . . |..|                  ..| .....  .. |  |||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK614.AA Pkinase 521-713 22 1.5e-16 59.57 Pfam 1-205 (293) Show / Hide 
Range on Protein: 521-713
Range on HMM: 1-205/293
Sequence Identity: 22% (47 aa)

TLTKEELGRGSYAVVKVGIFRGLR--VAVKSLHTIIISDFNLALFSR--EMSIASRVRHPNLVQFIGATK-VGNPLILTELMST-----SLNQELR---R
  ... .|.||...|. .. .| .  |||| .    ...  .    |  | .|  |..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NRL--TNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLK-PCTGPAGYEAKVADYGTAKLVQVDSTGTIMPGNVA---YAAPEAPI-PDQHSPA
...  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||...    .. | . .    |.|||       ..|.
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

MDVYSYSVLLMEM
 |..|. ..| ||
VDMWSCGCILYEM
Kinase AqueK614.AA MLK 738-763 30 3e-06 18.05 In-house 266-291 (291) Show / Hide 
Range on Protein: 738-763
Range on HMM: 266-291/291
Sequence Identity: 30% (8 aa)

MKSLIQRGLNASPRARPTMAQVIESL
.|.|...  |. |. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK614.AA Dicty4 739-765 31 6.2e-05 12.59 In-house 249-277 (277) Show / Hide 
Range on Protein: 739-765
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNASPRARPTMAQVIES--LKK
|.|||. .. .|  ||.....|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK614.AA Dicty4-Unclassified 738-763 42 8e-05 12.41 In-house 238-263 (263) Show / Hide 
Range on Protein: 738-763
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNASPRARPTMAQVIESL
.|.||   .  .|. |||| |.|. |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK614.AA LRRK 728-765 23 0.000138 12.13 In-house 314-351 (351) Show / Hide 
Range on Protein: 728-765
Range on HMM: 314-351/351
Sequence Identity: 23% (9 aa)

VQSGSVSWSDMKSLIQRGLNASPRARPTMAQVIESLKK
.. . . | ....|||   .. |. ||.. |... |. 
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK614.AA TK 735-763 24 0.003883 5.51 In-house 446-486 (486) Show / Hide 
Range on Protein: 735-763
Range on HMM: 446-486/486
Sequence Identity: 24% (10 aa)

W------------SDMKSLIQRGLNASPRARPTMAQVIESL
|             ..  |.|.  .. |. |||..|. | |
WMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK614.AA TKL-Unique 741-763 34 0.005519 6.58 In-house 268-290 (290) Show / Hide 
Range on Protein: 741-763
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLNASPRARPTMAQVIESL
|||.. .  |  ||.  ..|..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK614.AA TK-Unique 729-763 22 0.035732 3.44 In-house 260-294 (294) Show / Hide 
Range on Protein: 729-763
Range on HMM: 260-294/294
Sequence Identity: 22% (8 aa)

QSGSVSWSDMKSLIQRGLNASPRARPTMAQVIESL
|  ...  .| .|... .. .|  ||. .|..  |
QPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase AqueK614.AA CZAK 735-763 31 0.170953 1.38 In-house 251-279 (279) Show / Hide 
Range on Protein: 735-763
Range on HMM: 251-279/279
Sequence Identity: 31% (9 aa)

WSDMKSLIQRGLNASPRARPTMAQVIESL
| ..  || .  | .|  ||.  |... |
WKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase AqueK614.AA Pkinase_Tyr 735-763 24 0.292882 4.89 Pfam 242-270 (270) Show / Hide 
Range on Protein: 735-763
Range on HMM: 242-270/270
Sequence Identity: 24% (7 aa)

WSDMKSLIQRGLNASPRARPTMAQVIESL
. .. .|...  .. |  |||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK614.AA Pkinase 732-763 20 4.356871 1.39 Pfam 244-293 (293) Show / Hide 
Range on Protein: 732-763
Range on HMM: 244-293/293
Sequence Identity: 20% (10 aa)

SVSW----------------SDMKSLIQRGLNASPRARPTMAQVIES--L
|.|.                ...|..| . |.  |  ||| .|. ..  .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF