AqueK615

Species: A.queenslandica
Alias: AqueK615
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK615.AA Protein None 876 None Fasta, JSON
AqueK615.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of AqueK615.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_1 AqueK615.AA Kelch_1 13-70 15 0.228607 8.67 Pfam 1-45 (45) Show / Hide
Range on Protein: 13-70
Range on HMM: 1-45/45
Sequence Identity: 15% (9 aa)

GRAFHRTVSVDDSLYVWAGKLEDGLPEVHDSEEKRRITSNIQHFTPSTGQWITRATTG
 |..|  ..... .||  |                ......  . |.|.||   .. .
PRCGHGVCVHNGKIYVIGGCDG-------------QYLNSVECYDPETNQWTRCPPMP

Kelch_2 AqueK615.AA Kelch_2 13-31 26 12.254177 2.75 Pfam 1-19 (51) Show / Hide
Range on Protein: 13-31
Range on HMM: 1-19/51
Sequence Identity: 26% (5 aa)

GRAFHRTVSVDDSLYVWAG
.|. | ...... .||. |
PRYCHASCVPGGKIYVFGG

Kelch_2 AqueK615.AA Kelch_2 75-122 17 0.000119 21.8 Pfam 1-51 (51) Show / Hide
Range on Protein: 75-122
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GVRAYSCTAINDQLYYFGGW---CGHDDCYRNSITQLDTVSLQWRELEPTD
.    ... .....| |||.    ...||. ..|  .|. . .|... . .
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_1 AqueK615.AA Kelch_1 75-122 25 0.000568 18.01 Pfam 1-45 (45) Show / Hide
Range on Protein: 75-122
Range on HMM: 1-45/45
Sequence Identity: 25% (12 aa)

GVRAYSCTAINDQLYYFGGWCGHDDCYRNSITQLDTVSLQWRELEPTD
  . ......|...| .||..|    | ||.  .|... ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP

Kelch_2 AqueK615.AA Kelch_2 277-310 18 0.035163 12.41 Pfam 14-51 (51) Show / Hide
Range on Protein: 277-310
Range on HMM: 14-51/51
Sequence Identity: 18% (7 aa)

LVISGGF----DMNKDTLDDCWIFNITEHSWIKLDVPH
....||.    ..| . . | |...  .|.| .. ...
IYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP

Kelch_1 AqueK615.AA Kelch_1 277-306 16 0.184947 9.0 Pfam 14-41 (45) Show / Hide
Range on Protein: 277-306
Range on HMM: 14-41/45
Sequence Identity: 16% (5 aa)

LVISGGFDMNKDTLDDCWIFNITEHSWIKL
. . ||.|     |....... ....| ..
IYVIGGCDG--QYLNSVECYDPETNQWTRC

Kinase AqueK615.AA TKL 635-871 19 2.7e-46 160.1 In-house 1-364 (364) Show / Hide
Range on Protein: 635-871
Range on HMM: 1-364/364
Sequence Identity: 19% (71 aa)

LGRGSYAVVTVGIFRG----------LRVAVKSLHNIIISNYNR-------------------------GLFSREMSIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ..    .. ..                           . .|. . || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLILTELL-STSLNQELRRNQLTNQQILSIAQDVALGLNYLHLFKP-----QPIIHRDVSSPNVLLKPCTGP---------AGYEAKV
          |.. | .|.    ||   |       .|....|.|.|.|.||||  .|      ||||||  |.|.|..    .         | . .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

ADYGTAKLVQVDS--------------------TGTVMPGNVAYAAPEAPIPD----------------QHSPAMDVYSYSVLLMEMNLCSPPEMTTAER
.|.|... .. ..                    |     |. .. |||.   .                . |...||||. ..| |.  . .|.    ..
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

EVQ---------SGSV-----------------------SWSDMKSLIQRGLNANPRARPTMAQVIESL
...         .. .                        . .||.|.|.  ...|..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase AqueK615.AA MLK 629-821 25 3.3e-31 105.56 In-house 1-229 (291) Show / Hide
Range on Protein: 629-821
Range on HMM: 1-229/291
Sequence Identity: 25% (59 aa)

TLTKEELGRGSYAVVTVGIFRGLR-----VAVKSLH-NIIISNYN----RGLFSREMSIASRVRHPN----LVQFIGA-TKVGN-PLILTELLST-SLNQ
 ...| .| ||. .|  | .|. .     ||||  . .|. .       .  | .|  ......|||     .|| |. .. ..  .|..| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELRRNQ---------------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKP-CTGPAGYEAKVADYGTAKLVQVD-STGTVMPGNVAY
 |. ..                . ......| ..| |..|||  .|.||||||  |.|.|.   |   ..  .|..| ||.. ..   .. . ..|..|.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

AAPEAP---IPDQHSPAMDVYSYSVLLMEM
 |||.      .. | . ||.|. |.| ||
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEM

Kinase AqueK615.AA TKL-Unique 631-821 29 6.9e-30 102.66 In-house 1-221 (290) Show / Hide
Range on Protein: 631-821
Range on HMM: 1-221/290
Sequence Identity: 29% (65 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLH-NIIISNYNRGLFSREMSIASRVR-HPNLVQFIGATK---VGNP--LILTELLST-SLNQELR--------
  . .|.|.|..|  |..||  ||.|..| |  .||  .  |..| .. .. . |||.|...|...   | .|   | .| ..  ||.  |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

---RNQLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTVM----------PGNVAYAAPEAPI
    . |..||....|.|.|.|..|||  .|  |||||  |.|.|.      | . .|..| |..|.   ....|.            |.  ..|||   
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

P--DQHSPAMDVYSYSVLLMEM
   .| |   ||||... | |.
MNFCQYSEKSDVYSFGIVLWEI

Kinase AqueK615.AA TK 629-871 14 1.4e-29 95.69 In-house 1-486 (486) Show / Hide
Range on Protein: 629-871
Range on HMM: 1-486/486
Sequence Identity: 14% (69 aa)

TLTKEELGRGSYA---VVTVGIFRGL---------------------------RVAVKSLHNIIISNYNRGL---------------FSREMSIAS--RV
    ..||.| .    .|  |. ||.                           .|||| |.    .. .. .               . .||.. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLILTELLS-TS----LNQELRRN-----------------------------------------------
.|||.|...|  |....            ..|..|. .  .    | . ||..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLTNQQILSIAQDVALGLNYLHLFKP---QPIIHRDVSSPNVLLKPCTG------PAGYEAKVADYG---
                              ||| .| | .....| |. |||  .    | ..|||.   |.|.             |. .|.||.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKLVQVDSTGTVMPGN---------------------------VAYAAPEAPI---------PDQHSPAMDVYSYSVLLMEMN-LC-SPPE--M
      |. .. |.  ... .                            . . |||.              .... ||.|. ||. |.  ..  |.   |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT---------------------------------AEREVQSGSVSW------------SDMKSLIQRGLNANPRARPTMAQVIESL
.                                   ...   .  .|             ..  |.|.  ...|. |||..|. | |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase AqueK615.AA S_TKc 629-874 18 5.2e-27 96.98 SMART 1-231 (231) Show / Hide
Range on Protein: 629-874
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

TLTKEELGRGSYAVVTVGIFRG--LRVAVKSLHNIIISNYNRGLFSREMSIASRVRHPNLVQFIGATKVGNPLILTELLST---SLNQELRRNQ------
    ...|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . .....      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTVMPGNVAYAAPEAPIPDQHSP-AMDVYSYS
 ..  .. .... ....|.|.|  .   |||||.   |.||         . |..| | |...      | . |   | |||     .... . |..|  
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLMEMNLCSPPEMTTAEREVQSGSVSWSDMKSLIQRGLNANPRARPTMAQVIE------SLKRM
..| ||    ||   . ..  .      ...|..|.. |. .|. |||  .. .      .   .
CILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase AqueK615.AA Dicty4 631-821 28 1.9e-21 68.47 In-house 3-210 (277) Show / Hide
Range on Protein: 631-821
Range on HMM: 3-210/277
Sequence Identity: 28% (62 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSL--HNIIISNYNRGLFSREMSIASRVRHPNLVQFIGA-T----KVGNPLILTELL-STSLNQELRR------N
. ...|.||.. |  |. ||  |||| |  ||.  . .    | .| .| .  ||||...| || |    . | ..| ||.. ...|   |.        
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

QLTNQ--QILS---IAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTV----MPGNVAYAAPEAPIPDQHSP
  . .   |..   .| |.|.|.|.||   |  |||||  | | |       . . .||.| | ... . ... .     . | ... |||    .    
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVD-----KNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

AMDVYSYSVLLMEM
. ||||.. .| |.
KADVYSFGIVLWEI

Kinase AqueK615.AA STE 630-798 17 5e-20 67.5 In-house 1-232 (359) Show / Hide
Range on Protein: 630-798
Range on HMM: 1-232/359
Sequence Identity: 17% (42 aa)

LTK-EELGRGSYAVVTVGIFR-----------------GLRVAVKSLH---------------NIIISNYNRGLFSREMSIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLILTELLS-TSLNQELRRN-----QLT----------NQQILSIAQDVALG-LNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAK
..        .  |  |...  || . ....     .|.           .||  |....  | |.|||  .   |||||. . |.||          .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VK

VADYGTAKLVQ-----------------VDSTGTVMPGNVAYAAPE
 .| |... ..                  ..  . . |   . |||
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE

Kinase AqueK615.AA LRRK 629-798 22 3e-19 64.72 In-house 1-249 (351) Show / Hide
Range on Protein: 629-798
Range on HMM: 1-249/351
Sequence Identity: 22% (57 aa)

TLTKEELGRGSYA-VVTVGIFRG----------------------------LRVAVKSLHNI----------------------------------IISN
    |..|||... .|  ...||                              ||.|... .                                   . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YNRGLFSREMSIASRVRHPNLVQFIGATKVGNPLIL-TELLST-SLNQELR---RNQ-------LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSP
..  .| .|..| |. .|||.|. .| .   .||.. .|...  .|.. |.   ...       .. . .| || ..| |..||| ..| ||||||  ||
FR--EFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSP

NVLLKPCTGP-------AGYEAKVADYGTAKLVQVDSTG--TVMPGNVAYAAPE
|.||.  . .       | . ||.||.|.  . |.. .|    . ||  . |||
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPE

Pkinase_Tyr AqueK615.AA Pkinase_Tyr 628-821 25 9.8e-19 64.08 Pfam 1-207 (270) Show / Hide
Range on Protein: 628-821
Range on HMM: 1-207/270
Sequence Identity: 25% (55 aa)

VTLTKEELGRGSYAVVTVGIFR------GLRVAVKSLHNIIISNYN--RGLFSREMSIASRV-RHPNLVQFIGATK-VGNP---LILTELLST-SLNQEL
.|.  ..||.|.. .|  |. .      .. ||||.| .   .  .  |  | ||..| .   .|||.|...|.    | |   .| .|.    .|   |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RRN-----QLTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTG-TVMP---GNVAYAAPEAPIPDQ
|..     .|| ...|......| |..||.  .   .||||.   |.|..      .  .|..| | |.... |..  ..       .   |||.     
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK

HSPAMDVYSYSVLLMEM
 . . ||.|. ||. |.
FTTKSDVWSFGVLMWEI

Kinase AqueK615.AA CZAK 724-821 30 2.5e-18 63.25 In-house 108-215 (279) Show / Hide
Range on Protein: 724-821
Range on HMM: 108-215/279
Sequence Identity: 30% (33 aa)

LSIAQDVALGLNYLHL-FKPQPIIHRDVSSPNVLLKPCTG--------PAGYEAKVADYGTAKLVQVDSTG-TVMPGNVAYAAPEAPIPDQHSPAMDVYS
...| |.| | ||||  .|| ||.||| || |.||                  .|..|.|  ..     .  |   | ... |||  . .  ..  ||||
WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYS

YSVLLMEM
.  .| ..
FGMILWCI

Kinase AqueK615.AA TyrKc 629-871 21 4.7e-17 52.98 SMART 1-280 (280) Show / Hide
Range on Protein: 629-871
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

TLTKEELGRGSYAVVTVGIFRGLRVAVKSLHNIIISNYNRGLFSREMSIASRV--RHPNLVQFIGATKV--------GNPLILTELLST-SLNQELRRNQ
   ...||.| . .|  |. . . ||||.|..       |  | ||..| ...  .|||.|...|.           . ..|..|. .  .|.. ||...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVD-------STGTV-----MP--GNVAYAAPEAPI
  |.... ||.. ..| | .|||     ..||||    |.|..         .|..| | .. .  |       .. ..           .   |||.  
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

PDQHSPAMDVYSYSVLLMEM-NLCSPPE-------MTTAE--REVQSG------SV--------SWSDMKSLIQRGLNANPRARPTMAQVIESL
    ... ||.|. |.. |.  .. .|        |. .|  . |..|                  ..| .....  ...|  |||.....| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase AqueK615.AA Dicty4-Unclassified 632-821 25 1.7e-16 52.97 In-house 4-201 (263) Show / Hide
Range on Protein: 632-821
Range on HMM: 4-201/263
Sequence Identity: 25% (54 aa)

KEELGRGSYAVVTVGIFRGLRVAVKSLHNIIISNYNRGL--FSREMSIASRVRHPNLVQFIGATKVGNP-------LILTELLSTSLNQELRR------N
  ..|.|  . |  |. .|  |||| .     .     .  | .|  |   . |||||.  |.    ||        | .|..      |.        .
DQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

Q---LTNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQVDSTGTVMPGNVAYAAPEAPIPDQHSPAMDVYS
|   |    |. .| |.| |. .||      .||||. | |.|.        . .|.|| | .  .    . |   | ..  .||         . ||||
QPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYS

YSVLLMEM
| ..| |.
YAMMLYEL

Kinase AqueK615.AA HH498 721-821 38 4.7e-14 40.55 In-house 121-219 (284) Show / Hide
Range on Protein: 721-821
Range on HMM: 121-219/284
Sequence Identity: 38% (40 aa)

QQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLKPCTGPAGYEAKVADYGTAKLVQV--DSTGTVMPGNVAYAAPEAPI-PDQHSPAMDVYSYSVL
| .. |. ||| | ||||   ..||||||  | |.|.      .   |.|||.|    |.   | . |  |||  . |||      . |   ||.||   
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH-----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMC

LMEM
. ||
IWEM

Kinase AqueK615.AA Pkinase 629-821 22 1.1e-13 49.41 Pfam 1-205 (293) Show / Hide
Range on Protein: 629-821
Range on HMM: 1-205/293
Sequence Identity: 22% (48 aa)

TLTKEELGRGSYAVVTVGIFRGLR--VAVKSLHNIIISN-YNRGLFS-REMSIASRVRHPNLVQFIGATK-VGNPLILTELLST-----SLNQELR---R
  ... .|.||...|  .. .| .  |||| .    ..   .. ..  .| .|  |..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NQL--TNQQILSIAQDVALGLNYLHLFKPQPIIHRDVSSPNVLLK-PCTGPAGYEAKVADYGTAKL--VQVDSTGTVMPGNVAYAAPEAPI-PDQHSPAM
. .  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|    |..| | ||.     .|  |.  |   |.|||       ..|. 
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSYSVLLMEM
|..|. ..| ||
DMWSCGCILYEM

Kinase AqueK615.AA CZAK 630-698 33 3.7e-08 25.9 In-house 1-74 (279) Show / Hide
Range on Protein: 630-698
Range on HMM: 1-74/279
Sequence Identity: 33% (25 aa)

LTKE-ELGRGSYAVVTVGIFRGLRVAVKSLHNIIISNYNR----GLFSREMSIASRVRHPNLVQFIGATKVGNP
|. . . |.| .  |  .  ||  ||.| .| .   |         | .| || |  .||| |||.||   ..|
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGP

Kinase AqueK615.AA MLK 846-871 30 2.5e-07 21.63 In-house 266-291 (291) Show / Hide
Range on Protein: 846-871
Range on HMM: 266-291/291
Sequence Identity: 30% (8 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.|...  |..|. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase AqueK615.AA HH498 631-693 33 6e-06 14.53 In-house 3-71 (284) Show / Hide
Range on Protein: 631-693
Range on HMM: 3-71/284
Sequence Identity: 33% (23 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLH-NIIISNYN-----RGLFSREMSIASRVRHPNLVQFIGAT
..|  | ||.  |  | .|.  ||||    . . .        .  | || || .|  ||. |||..|.
FHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYAC

Kinase AqueK615.AA Dicty4 847-873 31 2.5e-05 13.92 In-house 249-277 (277) Show / Hide
Range on Protein: 847-873
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNANPRARPTMAQVIES--LKR
|.|||. .. .|  ||.....|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase AqueK615.AA HH498 848-871 33 3.2e-05 12.07 In-house 261-284 (284) Show / Hide
Range on Protein: 848-871
Range on HMM: 261-284/284
Sequence Identity: 33% (8 aa)

SLIQRGLNANPRARPTMAQVIESL
.|||.. ...|  ||. .|..  |
NLIQMCWHPCPENRPDFDQIVTIL

Kinase AqueK615.AA LRRK 836-873 23 3.4e-05 14.33 In-house 314-351 (351) Show / Hide
Range on Protein: 836-873
Range on HMM: 314-351/351
Sequence Identity: 23% (9 aa)

VQSGSVSWSDMKSLIQRGLNANPRARPTMAQVIESLKR
.. . . | ....|||   ...|. ||.. |... |. 
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase AqueK615.AA TKL-Unique 849-871 34 0.000253 11.36 In-house 268-290 (290) Show / Hide
Range on Protein: 849-871
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLNANPRARPTMAQVIESL
|||.. . .|  ||.  ..|..|
LIQQCWHHDPSQRPSFDEIIHRL

Kinase AqueK615.AA Dicty4-Unclassified 846-871 42 0.000307 10.38 In-house 238-263 (263) Show / Hide
Range on Protein: 846-871
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.||   .   |. |||| |.|. |
WKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase AqueK615.AA Pkinase_Tyr 843-871 24 0.078855 6.82 Pfam 242-270 (270) Show / Hide
Range on Protein: 843-871
Range on HMM: 242-270/270
Sequence Identity: 24% (7 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESL
. .. .|...  ...|  |||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase AqueK615.AA CZAK 843-871 34 0.123447 1.9 In-house 251-279 (279) Show / Hide
Range on Protein: 843-871
Range on HMM: 251-279/279
Sequence Identity: 34% (10 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESL
| ..  || .  | ||  ||.  |... |
WKNLGELIEMCWNKNPDERPSFKQILQHL

Kinase AqueK615.AA Pkinase 840-871 20 0.469896 4.81 Pfam 244-293 (293) Show / Hide
Range on Protein: 840-871
Range on HMM: 244-293/293
Sequence Identity: 20% (10 aa)

SVSW----------------SDMKSLIQRGLNANPRARPTMAQVIES--L
|.|.                ...|..| . |. .|  ||| .|. ..  .
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF