Gene AqueK620 (A.queenslandica)

AqueK620

Species: A.queenslandica
Alias: AqueK620
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH-C

Sequence

Name Sequence Type Origin Length Description Download
AqueK620.AA Protein None 690 None Fasta, JSON
AqueK620.kin_dom Protein Kinase Domain None 245 None Fasta, JSON

Protein domain

Protein domains of AqueK620.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK620.AA Kelch_2 37-84 17 2.1e-05 24.64 Pfam 1-51 (51) Show / Hide 
Range on Protein: 37-84
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GVMQYSCTAINDQLYYFGGW---CGHGDCLHNSITQLDTISLQWRELEPTD
. .. ... .....| |||.    ...|| ...|  .|. . .|... . .
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK620.AA Kelch_1 37-84 22 0.001431 16.57 Pfam 1-45 (45) Show / Hide 
Range on Protein: 37-84
Range on HMM: 1-45/45
Sequence Identity: 22% (11 aa)

GVMQYSCTAINDQLYYFGGWCGHGDCLHNSITQLDTISLQWRELEPTD
    ......|...| .||..|      ||.  .|. . ||... |  
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK620.AA Kelch_2 227-273 13 0.072324 11.22 Pfam 1-51 (51) Show / Hide 
Range on Protein: 227-273
Range on HMM: 1-51/51
Sequence Identity: 13% (7 aa)

YHAGAIIITGCPMLVISGGW----DKNNDTLEDCWIFNIIQHSWIKLDVPH
.... ......  ....||.    . |.. . | |...   |.| .. ...
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK620.AA Kelch_1 227-269 13 0.311148 8.19 Pfam 1-41 (45) Show / Hide 
Range on Protein: 227-269
Range on HMM: 1-41/45
Sequence Identity: 13% (6 aa)

YHAGAIIITGCPMLVISGGWDKNNDTLEDCWIFNIIQHSWIKL
  .|. . .    . . ||.|     | ......   ..| ..
PRCGHGVCVHNGKIYVIGGCDG--QYLNSVECYDPETNQWTRC
Kinase AqueK620.AA TKL 447-685 20 3.5e-47 163.07 In-house 1-364 (364) Show / Hide 
Range on Protein: 447-685
Range on HMM: 1-364/364
Sequence Identity: 20% (74 aa)

LGRGSYAVVTVGIFRG----------LRVAVKSLHTIIISDYNL-------------------------ALFSREMNIASRVRHPNLVQFIGATK-----
.|.|....|  |..||            |||| ...   .  ..                           . .|... || ||||.|||.|. .     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

---------VGNPLVLTELM-STSLNQELRKSQLTNQQILSIAHNVALGLNYLHLFKP-----QPIIHRDISSPNVLLKPCTG-------PAGYDYEAKI
          |..   .|..   ||   |       .|....|. .|.|.||||  .|      ||||||. |.|.|..           .  .|. .||
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

GDYGTAKIVQAEN--------------------TDTVMPGNVAYAAPEAPIPD----------------QHSPAMDVYSYSILLMEMNLCSRPE------
.|.|... .. ..                    |     |. .. |||.   .                . |...||||. |.| |.  . ||.      
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------MTTAERELQSFSI--------------SWSDMKSLIQRGLNANPRARPTMAQVIESL
            |  ... |.                   . .||.|.|.  ...|..||.. .... |
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK620.AA MLK 441-635 25 2.2e-34 116.73 In-house 1-229 (291) Show / Hide 
Range on Protein: 441-635
Range on HMM: 1-229/291
Sequence Identity: 25% (60 aa)

ILTKEELGRGSYAVVTVGIFRGLR-----VAVKSLHTIIISDYNLA-----LFSREMNIASRVRHPN----LVQFIGA-TKVGN-PLVLTELMST-SLNQ
|...| .| ||. .|  | .|. .     ||||  .. |. |   .      | .| .......|||     .|| |. .. ..  ....| ..  ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ELRKSQ---------------LTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKP-CTGPAGYDYEAKIGDYGTAKIVQAE-NTDTVMPGNV
 |.  .                . ......|...| |..|||  .|.||||||. |.|.|.   |  .   .  .|| | ||.. ..    . . ..|..
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DM-HHGTLKICDFGTSRDWHQMCTNMMSNAGTY

AYAAPEAP---IPDQHSPAMDVYSYSILLMEM
|. |||.      .. | . ||.|. ..| ||
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEM
Kinase AqueK620.AA TK 441-685 13 7.3e-28 89.86 In-house 1-486 (486) Show / Hide 
Range on Protein: 441-685
Range on HMM: 1-486/486
Sequence Identity: 13% (68 aa)

ILTKEELGRGSYA---VVTVGIFRGL---------------------------RVAVKSLHTIIISDYNLAL---------------FSREMNIAS--RV
|   ..||.| .    .|  |. ||.                           .|||| |.    .. .  .               . .|| . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNLVQFIG-ATKVGN------------PLVLTELMS-TS----LNQELRKS-----------------------------------------------
.|||.|...|  |....            .....|.|.  .    | . |||.                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------QLTNQQILSIAHNVALGLNYLHLFKP---QPIIHRDISSPNVLLK-PCTGP---AGYDYEAKIGDYG---
                              ||| .| | ... .| |. |||  .    | ..|||.   |.|.    .      |. . .||.|.|   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TAKIVQAENTDTVMPGN---------------------------VAYAAPEAPI---------PDQHSPAMDVYSYSILLMEMN-LC-SRPE--M
      |. .. .   ... .                            . . |||.              .... ||.|. .|. |.  ..   .   |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT---------------------------------AERELQSFSISW------------SDMKSLIQRGLNANPRARPTMAQVIESL
.                                   ...      .|             ..  |.|.  ...|. |||..|. | |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK620.AA S_TKc 441-686 19 1.4e-26 95.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 441-686
Range on HMM: 1-231/231
Sequence Identity: 19% (51 aa)

ILTKEELGRGSYAVVTVGIFRG--LRVAVKSLHTIIISDYNLALFSREMNIASRVRHPNLVQFIGATKVGNPLVLTELMST---SLNQELRKSQ------
    ...|.|....|  .. ..   .||.| ..           . ||..| .. .|||.|.....   ..  . .|....   .| . ..| .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAENTDTVMPGNVAYAAPEAPIPDQHSP-AMDVYS
 ..  .. .... ....|.|.|  .   |||||.   |.||           . ||.| | |...      | . |   | |||     .... . |..|
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE---------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWS

YSILLMEMNLCSRPEMTTAERELQSFSISWSDMKSLIQRGLNANPRARPTMAQVIE--------SLK
  ..| ||     |   . .. ..      ...|..|.. |. .|. |||  .. .           
CGCILYEMLCGYPPFP-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK620.AA CZAK 442-635 29 1.8e-26 93.26 In-house 1-215 (279) Show / Hide 
Range on Protein: 442-635
Range on HMM: 1-215/279
Sequence Identity: 29% (64 aa)

LTKE-ELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNL----ALFSREMNIASRVRHPNLVQFIGATKVGN---PLVLTELMS-TSLNQELR-KSQLT
|. . . |.| .  |  .  ||  ||.| .| .   .         | .|  | |  .||| |||.||   ..     . .| |   || . |  .. . 
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

NQ---QILSIAHNVALGLNYLHL-FKPQPIIHRDISSPNVLLKPCTG------PAGYDYEAKIGDYGTA---KIVQAENTDTVMPGNVAYAAPEAPIPDQ
 |     ...|  .| | ||||  .|| ||.||| || |.||            .  |  .|| |.|     .    | | |.  | ... |||  . . 
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM--GCLCWMAPECFKGEN

HSPAMDVYSYSILLMEM
 ..  ||||. ..| ..
YTEKVDVYSFGMILWCI
Kinase AqueK620.AA Dicty4 441-635 28 1e-25 82.92 In-house 1-210 (277) Show / Hide 
Range on Protein: 441-635
Range on HMM: 1-210/277
Sequence Identity: 28% (63 aa)

ILTKEELGRGSYAVVTVGIFRGLRVAVKSL--HTIIISDYNLALFSREMNIASRVRHPNLVQFIGA-T----KVGNPLVLTELM-STSLNQELRK-----
| . ...|.||.. |  |. ||  |||| |  | .  . . |  | .| .| .  ||||...| || |    . | ..  ||.| ...|   |..     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-SQLTNQ--QILS---IAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAEN--TD--TVMPGNVAYAAPEAPIPD
 .  . .   |..   .|  .|.|.|.||   |  |||||. | | |          .. .|..| | ... . .   .|  . . | ... |||    .
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV-------DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQ

QHSPAMDVYSYSILLMEM
    . ||||..|.| |.
PYNEKADVYSFGIVLWEI
Kinase AqueK620.AA TKL-Unique 443-635 28 6.3e-25 84.95 In-house 1-221 (290) Show / Hide 
Range on Protein: 443-635
Range on HMM: 1-221/290
Sequence Identity: 28% (65 aa)

TKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNLA---LFSREMNIASRVR-HPNLVQFIGATK---VGNP--LVLTELMST-SLNQELR------
  . .|.|.|..|  |..||  ||.|..|    .| ..     |..| |. .. . |||.|...|...   | .|     .| ..  ||.  |       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP--NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

-----KSQLTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAENTDTVM----------PGNVAYAAP
     .. |..||....|. .|.|..|||  .|  |||||. |.|.|.      |   . .|| | |..|.   .|. |.            |.  ..||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIA--EWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EAPIP--DQHSPAMDVYSYSILLMEM
|      .| |   ||||..| | |.
EVLRMNFCQYSEKSDVYSFGIVLWEI
Kinase AqueK620.AA STE 442-635 16 6.5e-23 77.82 In-house 1-261 (359) Show / Hide 
Range on Protein: 442-635
Range on HMM: 1-261/359
Sequence Identity: 16% (46 aa)

LTK-EELGRGSYAVVTVGIFR-----------------GLRVAVKSLH---------------TIIISDYNLALFSREMNIASRVR--HPNLVQFIGATK
... |..|.|.. .|  .. .                 | ..|.| ..               . .. . ..  . .|..| .. .  ||| |...|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG--------NPLVLTELMS-TSLNQELR---KSQLT------------NQQILSIAHNVALG-LNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYE
..        .  .  |.|.  || . ..   . . .             .||  |.. .  | |.|||  .   |||||| . |.||            
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL------------

AKIGDYGTAKIVQAEN-----------------TDTVMPGNVAYAAPEAPIP------DQHSPAMDVYSYSILLMEM
.|. | |...... ..                   . . |   . |||   .      ....   |..|  ....||
VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase AqueK620.AA Pkinase_Tyr 441-635 24 7e-19 64.56 Pfam 1-207 (270) Show / Hide 
Range on Protein: 441-635
Range on HMM: 1-207/270
Sequence Identity: 24% (54 aa)

ILTKEELGRGSYAVVTVGIFR------GLRVAVKSLHTIIISDYN--LALFSREMNIASRV-RHPNLVQFIGATK-VGNP---LVLTELMST-SLNQELR
|   ..||.|.. .|  |. .      .. ||||.|     .. .  .. | ||..| .   .|||.|...|.    | |   .. .|.|   .|   ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KS-----QLTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAENTD-TVMP---GNVAYAAPEAPIPD
|      .|| ...|.... .| |..||.  .   .||||.   |.|..        .  .||.| | |. .. . .  ..       .   |||.    
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTE-------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYG

QHSPAMDVYSYSILLMEM
  . . ||.|. .|. |.
KFTTKSDVWSFGVLMWEI
Kinase AqueK620.AA Dicty4-Unclassified 441-635 26 9.2e-19 60.85 In-house 1-201 (263) Show / Hide 
Range on Protein: 441-635
Range on HMM: 1-201/263
Sequence Identity: 26% (56 aa)

ILTKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDY--NLALFSREMNIASRVRHPNLVQFIGATKVGNP-------LVLTELMSTSLNQELRKSQLT
|    ..|.|  . |  |. .|  |||| .     .     .  | .|  |   . |||||.  |.    ||        . .|.|      |.  |.  
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI--NPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

NQQ---------ILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAENTDTVMPGNVAYAAPEAPIPDQHSPA
 ||         |. .|  .| |. .||      .||||| | |.|.         .. .||.| | .  .    . |   | ..  .||         .
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMD-------KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQK

MDVYSYSILLMEM
 ||||| ..| |.
SDVYSYAMMLYEL
Kinase AqueK620.AA LRRK 441-589 21 9e-18 59.43 In-house 1-224 (351) Show / Hide 
Range on Protein: 441-589
Range on HMM: 1-224/351
Sequence Identity: 21% (49 aa)

ILTKEELGRGSYA-VVTVGIFRG----------------------------LRVAVKSLHT--------------------------------IIISDYN
.   |..|||... .|  ...||                              ||.|....                                .. .  .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LALFSREMNIASRVRHPNLVQFIGATKVGNPLVL-TELMST-SLNQELRKSQ----------LTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNV
. .| .|. | |. .|||.|. .| .   .|| . .|...  .|.. |....          .. . .| || ..| |..||| ..| ||||||  |||.
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LLKPCTGP-----AGYDYEAKIGDYGT
||.  . .      . .. |||.|.|.
LLWSSPQNHSPNYPNAHVCAKIADFGI
Kinase AqueK620.AA TyrKc 441-685 20 4.2e-17 53.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 441-685
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

ILTKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYNLALFSREMNIASRV--RHPNLVQFIGATKV--------GNPLVLTELMST-SLNQELRKSQ
|  ...||.| . .|  |. . . ||||.|.        .. | ||..| ...  .|||.|...|.           . .....|.|.  .|.. |||..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--LTNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLKPCTGPAGYDYEAKIGDYGTAKIVQAE-------NTDTV-----MP--GNVAYAAPEA
  |.... ||... .| | .|||     ..||||.   |.|..           .||.| | .. .  .        . ..           .   |||.
PKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

PIPDQHSPAMDVYSYSILLMEM-NLCSRPE-------MTTAE--------RELQSFSI--------SWSDMKSLIQRGLNANPRARPTMAQVIESL
      ... ||.|. ... |.  ..  |        |. .|        . .               ..| .....  ...|  |||.....| .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK620.AA DRK 441-568 36 1.4e-15 49.32 In-house 1-132 (258) Show / Hide 
Range on Protein: 441-568
Range on HMM: 1-132/258
Sequence Identity: 36% (48 aa)

ILTKEELGRGSYAVVTVGIFRGLRVAVKSLHTIIISDYN-LALFSREMNIASRVRHPNLVQFIGA-TKVGNPLVLTELMST-SLNQELRKSQLTNQ--QI
|      |||.|. |  |  ||  |||| |    | | | |  | || |. .. |||| .||.|. .    ... .| |.  || . |    .  .   .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LSIAHNVALGLNYLHLFKPQPIIHRDISSPNVL
....  .| |..|||   |  |||||  | | |
KQMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLL
Kinase AqueK620.AA Pkinase 441-635 22 2.8e-15 55.08 Pfam 1-205 (293) Show / Hide 
Range on Protein: 441-635
Range on HMM: 1-205/293
Sequence Identity: 22% (48 aa)

ILTKEELGRGSYAVVTVGIFRGLR--VAVKSLHTIIISDYNLALFSR--EMNIASRVRHPNLVQFIGATK-VGNPLVLTELMST-----SLNQELR---K
. ... .|.||...|  .. .| .  |||| .    ...  .    |  |  |  |..||| |.....    ... . .|..       .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SQL--TNQQILSIAHNVALGLNYLHLFKPQPIIHRDISSPNVLLK-PCTGPAGYDYEAKIGDYGTAKIVQAENTDTVMPGNVA---YAAPEAPI-PDQHS
  .  . ... ...  .. ||.|.|      |||||. . |.|..  .. .|      ||.| | || .. .  .. | . .    |.|||       ..
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA----CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

PAMDVYSYSILLMEM
|. |..|. ..| ||
PKVDMWSCGCILYEM
Kinase AqueK620.AA MLK 660-685 30 2.5e-07 21.63 In-house 266-291 (291) Show / Hide 
Range on Protein: 660-685
Range on HMM: 266-291/291
Sequence Identity: 30% (8 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.|...  |..|. ||...|... |
WKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK620.AA Dicty4 661-687 31 5.5e-05 12.77 In-house 249-277 (277) Show / Hide 
Range on Protein: 661-687
Range on HMM: 249-277/277
Sequence Identity: 31% (9 aa)

KSLIQRGLNANPRARPTMAQVIES--LKG
|.|||. .. .|  ||.....|.   |  
KHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK620.AA LRRK 657-687 29 7.1e-05 13.16 In-house 321-351 (351) Show / Hide 
Range on Protein: 657-687
Range on HMM: 321-351/351
Sequence Identity: 29% (9 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESLKG
| ....|||   ...|. ||.. |... |. 
WHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase AqueK620.AA DRK 663-687 32 0.000167 11.21 In-house 234-258 (258) Show / Hide 
Range on Protein: 663-687
Range on HMM: 234-258/258
Sequence Identity: 32% (8 aa)

LIQRGLNANPRARPTMAQVIESLKG
|... .| .|  ||.| ...| |  
LMNDCWNEDPQHRPSMQECLERLEA
Kinase AqueK620.AA TKL-Unique 663-685 34 0.000253 11.36 In-house 268-290 (290) Show / Hide 
Range on Protein: 663-685
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LIQRGLNANPRARPTMAQVIESL
|||.. . .|  ||.  ..|..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK620.AA Dicty4-Unclassified 660-685 42 0.000307 10.38 In-house 238-263 (263) Show / Hide 
Range on Protein: 660-685
Range on HMM: 238-263/263
Sequence Identity: 42% (11 aa)

MKSLIQRGLNANPRARPTMAQVIESL
.|.||   .   |. |||| |.|. |
WKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase AqueK620.AA CZAK 651-685 31 0.062775 2.98 In-house 245-279 (279) Show / Hide 
Range on Protein: 651-685
Range on HMM: 245-279/279
Sequence Identity: 31% (11 aa)

QSFSISWSDMKSLIQRGLNANPRARPTMAQVIESL
| ..  | ..  || .  | ||  ||.  |... |
QPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase AqueK620.AA Pkinase_Tyr 657-685 24 0.078855 6.82 Pfam 242-270 (270) Show / Hide 
Range on Protein: 657-685
Range on HMM: 242-270/270
Sequence Identity: 24% (7 aa)

WSDMKSLIQRGLNANPRARPTMAQVIESL
. .. .|...  ...|  |||.....| |
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK620.AA Pkinase 648-685 16 0.295939 5.52 Pfam 233-293 (293) Show / Hide 
Range on Protein: 648-685
Range on HMM: 233-293/293
Sequence Identity: 16% (10 aa)

RELQSFSISW---------------------SDMKSLIQRGLNANPRARPTMAQVIES--L
..| . .  |                     ...|..| . |. .|  ||| .|. ..  .
PPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF