Gene AqueK644 (A.queenslandica)

AqueK644

Species: A.queenslandica
Alias: AqueK644
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: HH498

Sequence

Name Sequence Type Origin Length Description Download
AqueK644.AA Protein None 1332 None Fasta, JSON
AqueK644.kin_dom Protein Kinase Domain None 237 None Fasta, JSON

Protein domain

Protein domains of AqueK644.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kelch_2 AqueK644.AA Kelch_2 140-196 17 8.4e-05 22.38 Pfam 1-51 (51) Show / Hide 
Range on Protein: 140-196
Range on HMM: 1-51/51
Sequence Identity: 17% (10 aa)

ERSGHSTVRVGDYLYMWGGWQFGLPEVHDNEKKKSMCSVMEVCHLRTGRWEQKPTTG
 |..|... .|. .|..||.        ..  . . .... .....| ||.  |  .
PRYCHASCVPGGKIYVFGGYC------RHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK644.AA Kelch_1 140-196 17 0.096063 10.02 Pfam 1-45 (45) Show / Hide 
Range on Protein: 140-196
Range on HMM: 1-45/45
Sequence Identity: 17% (10 aa)

ERSGHSTVRVGDYLYMWGGWQFGLPEVHDNEKKKSMCSVMEVCHLRTGRWEQKPTTG
 |.||. . .....|  ||.              .  .  |. ...|..|.. |. .
PRCGHGVCVHNGKIYVIGGCDG------------QYLNSVECYDPETNQWTRCPPMP
Kelch_1 AqueK644.AA Kelch_1 201-248 20 5.8e-05 21.55 Pfam 1-45 (45) Show / Hide 
Range on Protein: 201-248
Range on HMM: 1-45/45
Sequence Identity: 20% (10 aa)

GVKSYAAAAIGREIFYFGGDCGHLGCYHNSLYSFNVDTFNWKELSPTT
   ........ .|. .|| .|    | || ......|  |....| .
PRCGHGVCVHNGKIYVIGGCDG---QYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK644.AA Kelch_2 201-248 17 2.760637 5.21 Pfam 1-51 (51) Show / Hide 
Range on Protein: 201-248
Range on HMM: 1-51/51
Sequence Identity: 17% (9 aa)

GVKSYAAAAIGREIFYFGGD---CGHLGCYHNSLYSFNVDTFNWKELSPTT
.  . |.. .|  |. |||     .. .|...... .. .|  |.....  
PRYCHASCVPGGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_2 AqueK644.AA Kelch_2 385-430 23 0.001478 17.64 Pfam 1-51 (51) Show / Hide 
Range on Protein: 385-430
Range on HMM: 1-51/51
Sequence Identity: 23% (13 aa)

ERRAHSSVLINTSSGPHLLVVGGY---------DAHDIWIFDISNKSWKELNCSK
 |  |.|. .    |  ..|.|||         .  |||..| . ..|..... .
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK644.AA Kelch_1 396-430 15 0.009395 13.64 Pfam 8-45 (45) Show / Hide 
Range on Protein: 396-430
Range on HMM: 8-45/45
Sequence Identity: 15% (6 aa)

TSSGPHLLVVGGYD---AHDIWIFDISNKSWKELNCSK
.. . .. |.||.|     .....| ....|...   .
CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK644.AA Kelch_2 443-489 27 0.007319 15.0 Pfam 1-51 (51) Show / Hide 
Range on Protein: 443-489
Range on HMM: 1-51/51
Sequence Identity: 27% (15 aa)

RRYAHSSVLINTSSGPHLLVVGGY--------YQAYDIWIFDINNKSWKELVNIP
.|| |.|. .    |  ..|.|||            |||..| . ..|...  .|
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK644.AA Kelch_1 443-489 18 0.061279 10.72 Pfam 1-45 (45) Show / Hide 
Range on Protein: 443-489
Range on HMM: 1-45/45
Sequence Identity: 18% (9 aa)

RRYAHSSVLINTSSGPHLLVVGGYY--QAYDIWIFDINNKSWKELVNIP
.|. |... .|     .. |.||.      .....|  ...|... . |
PRCGHGVCVHNG----KIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK644.AA Kelch_2 633-660 16 11.888616 2.8 Pfam 16-51 (51) Show / Hide 
Range on Protein: 633-660
Range on HMM: 16-51/51
Sequence Identity: 16% (6 aa)

LFSGY--------HRCNEIHFYKLSTGQWISPNVTG
.|.||        .... |... ..| .|   .. .
VFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kelch_1 AqueK644.AA Kelch_1 732-766 18 0.000284 19.09 Pfam 8-45 (45) Show / Hide 
Range on Protein: 732-766
Range on HMM: 8-45/45
Sequence Identity: 18% (7 aa)

TSSGPHLLVVGGYC---TNDIWIFDINNKSWKELVNIP
.. . .. |.||..   .|.....|  ...|... . |
CVHNGKIYVIGGCDGQYLNSVECYDPETNQWTRCPPMP
Kelch_2 AqueK644.AA Kelch_2 721-766 25 0.000564 19.23 Pfam 1-51 (51) Show / Hide 
Range on Protein: 721-766
Range on HMM: 1-51/51
Sequence Identity: 25% (14 aa)

KRGAHSSVLINTSSGPHLLVVGGY---------CTNDIWIFDINNKSWKELVNIP
 |. |.|. .    |  ..|.|||          ..|||..| . ..|...  .|
PRYCHASCVP----GGKIYVFGGYCRHTHNNDCWSMDIWWWDPETHRWTCVPRMP
Kinase AqueK644.AA TKL 1098-1328 18 1.2e-43 151.35 In-house 1-364 (364) Show / Hide 
Range on Protein: 1098-1328
Range on HMM: 1-364/364
Sequence Identity: 18% (67 aa)

LGKGGWGEVKVAGFRG----------LKVAAKCLYEVIISPYNI-------------------------GTFSREMNIASKIRHPNLLQFIGATTEGN--
.|.|| |||  . .||            || | . .   .  ..                          .. .|... |..||||..||.|. ....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PIILTELM-PTSLRKELESGGVAYPAILSISLDVACALNYLHLFKP-----HPILHRDVSSANVLLQITG-----------GTWKAKV
            . | .|..   ||.  |       . .....||.|...||||  .|      ||.|||  |.|.|.   .            .|..|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKI

SDYGTVS----------------------LQPLARTSNPGNPVYSAPES-----PYPN-----------QHSPAMDVFSYGVLLIEMVVCE--FPDVGKR
.|.|.                        ..  .. .  |.| . |||      .|..           . |...||.|.|..| |.. ..  . | . .
CDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYM

------------VAQIKAIKRPTLK--------------------NLIECCLIENYKDRLAMSDIIKEL
            .  ..  .||...                    .|...|  .. ..|. ...|.|.|
PMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK644.AA CZAK 1095-1286 31 1.2e-25 90.2 In-house 4-221 (279) Show / Hide 
Range on Protein: 1095-1286
Range on HMM: 4-221/279
Sequence Identity: 31% (70 aa)

EVVLGKGGWGEVKVAGFRGLKVAAKCLYEVIISPYNIGT------FSREMNIASKIRHPNLLQFIGATTEGN---PIILTELMP-TSLRKELE--SGGVA
. . |.|  |||. |  ||  || | ..   ..  |         | .|  | || .||| .||.|| .|..     | .| |   |||. |   .  . 
GQTIGQGFFGEVYKAYWRGKDVAIKIIH--RNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYHK

Y-PAI-LSISLDVACALNYLHL-FKPHPILHRDVSSANVLLQ--IT--------GGTWKAKVSDYGTV---SLQPLARTSNPGNPVYSAPESPYPNQHSP
  | . ... .|.|   ||||  .|| |||||| || |.||   .|            ..|..|.|       ||   |.  |   . |||       ..
QNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTE

AMDVFSYGVLLIEMVVCEFP
  ||.|.| .| ... |. |
KVDVYSFGMILWCIITCDQP
Kinase AqueK644.AA MLK 1092-1286 24 5.9e-22 73.05 In-house 1-235 (291) Show / Hide 
Range on Protein: 1092-1286
Range on HMM: 1-235/291
Sequence Identity: 24% (58 aa)

TMTEVVLGKGGWGEVKVAGFRGLKVAAKC--LYEVIISPYNIGT-------FSREMNIASKIRHPN----LLQFIGATTE-GN-PIILTELMPT-SLRKE
  .. ..|.|. |.|  . .|.  . ||   ...| .... ..        | .| .......|||      || |. .. ..   |..| ..  ||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LESG---------------GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQI-----TGGTWKAKVSDYGTVS-LQPL-A-RTSNPGNPV
| ..                .    .....|..| ...|||  .|.|| |||  | |.|.        .||  .|..| ||.  ..   . ..||.|.. 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGT--LKICDFGTSRDWHQMCTNMMSNAGTYA

YSAPESP---YPNQHSPAMDVFSYGVLLIEMVVCEFP
. |||       .. | . ||.|.||.| ||. .| |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase AqueK644.AA TKL-Unique 1097-1281 25 1.4e-20 69.42 In-house 4-222 (290) Show / Hide 
Range on Protein: 1097-1281
Range on HMM: 4-222/290
Sequence Identity: 25% (57 aa)

VLGKGGWGEVKVAGFRGLKVAAKCLY-EVIISPYNIGTFSREMNIASKIR-HPNLLQFIGATT-----EGNPIILTELMPT-SLRKELE-----------
..| || |.|. . .|| .|| | .  .  .|.  . .|..| |. .|.. |||.....|...     ..| .| .| .|  ||.. |            
KIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNN

SGGVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGT----WKAKVSDYGTVSLQP--LARTSN----------PGNPVYSAPESPYP
.    .  .... .|.| ...|||  .|  |.|||  | |.|  .. .     |..|..| |.. ..   .. |.|           |.. ..|||    
NCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFL--VDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--NQHSPAMDVFSYGVLLIEMV
  .| |   ||.|.|. |.|..
NFCQYSEKSDVYSFGIVLWEIA
Kinase AqueK644.AA S_TKc 1092-1332 21 1.2e-18 69.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 1092-1332
Range on HMM: 1-231/231
Sequence Identity: 21% (55 aa)

TMTEVVLGKGGWGEVKVAGFRG--LKVAAKCLYEVIISPYNIGTFSREMNIASKIRHPNLLQFIGATTEGNPIILTELMPT---SLRKELESGG------
     ..|||. |.|. .  ..   .|| |..           .. ||..| .| .|||. .....  ...  . .|....   .|.. ... |      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGTWKAKVSDYGTVSLQPLARTSNPGNPVYSAPESPYPNQHSP-AMDVFSYGVLLI
      . ..   ..|||.|.|  .   |.|||.  .|.||         |..| |   .     |.  | | | |||     .... . |. | |..|.
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMVVCEFPDVGKRVAQIKAIKRPTLKNLIECCLIENYKDRLAMSDIIK-----ELNESI
||.. . |      . .| |. | .|..|. ||  . ..|.   .. .      . . .
EMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK644.AA TK 1136-1328 12 9.6e-17 51.93 In-house 87-486 (486) Show / Hide 
Range on Protein: 1136-1328
Range on HMM: 87-486/486
Sequence Identity: 12% (51 aa)

REMNIASKIR-----HPNLLQFIGATTEGN-------------PIILTELMP-TS----LRKELESGG--------------------------------
.|...... .     |||.....|. |.|              ..|..|.||  .    ||. | .                                  
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

---------------------------------------------VAYPAILSISLDVACALNYLHLFKPHPI----LHRDVSSANVLLQITGG-TWK--
                                             .  .  | .....||.. |||  .         |||.   |.|.   .  .|.  
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFD

-----AKVSDYG--------TVSLQPL----ARTSNPGNPV-------------------------YSAPESPY---------PNQHSPAMDVFSYGVLL
     .|..|.|             .      |.|..| ..                         . |||.            . .... ||.|.|||.
GCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM

IEMVV-C-EFPDVGKR-------------VAQIKAI-----------------KRPTLKN-------------------LIECCLIENYKDRLAMSDIIK
 |..  . | .  |               . ....                  ..| .                     |. .|  .. .||  .|.. .
WEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHE

EL
.|
QL
Kinase AqueK644.AA Dicty4 1094-1235 32 3.6e-16 50.6 In-house 3-159 (277) Show / Hide 
Range on Protein: 1094-1235
Range on HMM: 3-159/277
Sequence Identity: 32% (52 aa)

TEVVLGKGGWGEVKVAGFRGLKVAAKCL--YEVIISPYNIGTFSREMNIASKIRHPNLLQFIGATT-----EGNPIILTELM-PTSLRKELES------G
.|. .|||. |||  .  || .|| | |    .  . . .  | .| .| .||||||...| || |      | . | ||.|  ..| . | .       
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

GVAYP--AILS---ISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGTWKAKVSDYG
 .  .   |..   . .|.|  .|.||   |  |.|||  |.| |  .    |..||.| |
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDK---NWRVKVCDFG
Kinase AqueK644.AA Dicty5 1129-1280 28 4.6e-16 51.79 In-house 38-196 (260) Show / Hide 
Range on Protein: 1129-1280
Range on HMM: 38-196/260
Sequence Identity: 28% (47 aa)

YNIGTFSREMNIASKIR--HPNLLQFIGATTEGNPI--ILTELMPT-SLRKELESGGV------AYPAILSISLDVACALNYLHLFKPHPILHRDVSSAN
...  | ||  | | .   |||.  . || .       ..||.    ||.  |           ||. .|.. .|.| .. .||      | |||. | |
FDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMN

VLLQITGGTWKAKVSDYGT---VSLQPLARTSNPGNPVYSAPESPYPNQHSPAMDVFSYGVLLIEM
.|.      ||.|. |.||   | .. .  | . | . . |.|    .      ||.|.|. | ||
FLITE---NWKIKIIDFGTSRFVDNR-YHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEM
Kinase AqueK644.AA HH498 1184-1286 37 8.2e-16 46.23 In-house 121-225 (284) Show / Hide 
Range on Protein: 1184-1286
Range on HMM: 121-225/284
Sequence Identity: 37% (40 aa)

PAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGTWKAKVSDYG----TVSLQPLARTSNPGNPVYSAPESPY-PNQHSPAMDVFSYGVLLI
. .. ||.|||   ||||   .||| |||  | |.|.   |   .|.| |.|      ..     |. |||. . |||      . |   |||||.  . 
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDG---HAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIW

EMVVCEFP
||   | |
EMHTREVP
Kinase AqueK644.AA DRK 1093-1235 34 1.4e-15 49.23 In-house 2-145 (258) Show / Hide 
Range on Protein: 1093-1235
Range on HMM: 2-145/258
Sequence Identity: 34% (51 aa)

MTEVVLGKGGWGEVKVAGFRGLKVAAKCLYEVIIS-PYNIGTFSREMNIASKIRHPNLLQFIGATTE-GNPIILTELMPT-SLRKEL--ESGGVAYPAIL
   .  |.|..|||     || .|| | |    |     .  | || |. .. ||||  ||.|. ..   . | .| ||  || . |  ||     | ..
KIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMK

SISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGTWKAKVSDYG
.. .|.|  ..|||   |  |.|||  | | |       |. ||.|.|
QMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLLVD---EHWQVKVADFG
TyrKc AqueK644.AA TyrKc 1091-1328 22 2.1e-14 10.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 1091-1328
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

ITMTEVVLGKGGWGEVKVAGFRGLKVAAKCLYEVIISPYNIGTFSREMNIASKI--RHPNLLQFIGATTE--------GNPIILTELMPT-SLRKELESG
||. . .|| |  |||  .  . ..|| |.| |       .  | ||..| .|.  .|||.....|. |.        . . |..|.||  .|.. | . 
ITLGK-KLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

G--VAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGTWKAKVSDYGTVSLQPLARTSNPG------NPVYS----------------A
.  .  .  ||.....||  .|||    ... |||    |.|.   .    .|.|| |      |.|    .        .|.                |
RPKLCMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH---TVKISDFG------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PESPYPNQH--SPAMDVFSYGVLLIEMV-------------------VCEFPDVGKRVAQIKA-------IKRPTLKNLIECCLIENYKDRLAMSDIIKE
||.   | .  ... ||.|.||.. |.                    | |. . |.|  | .        .  . . .....|  |. .||  .|.|...
PECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase AqueK644.AA Pkinase 1092-1332 17 1.4e-12 45.56 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1092-1332
Range on HMM: 1-293/293
Sequence Identity: 17% (54 aa)

TMTEVVLGKGGWGEVKVAGFRGLK--VAAKCLYEVIISPYNIGTFSR--EMNIASKIRHPNLLQFIGAT-TEGNPIILTELMPT-----SLRKELE---S
  .. ..|.|. |.|. .  .|    || |..  . ...    |  |  |  |  ...||| ......  ..... . .|...      .|   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGV--AYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLLQITGGT-WKAKVSDYGTVS---LQPLARTSNPGNPVYSAPESPY-PNQHSPAMDVF
|..   .  . .. . ....|.|.|      |.|||. ..|.|.  .| .  . |..| |      . .   |.  | | | |||     . ..|. |..
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYGVLLIEMVVCEFPDVGK----------RVAQIKA-------IKR---------------------PTLKNLIECCLIENYKDRLAMSDIIKELNES--
|.|..|.||.  ..|  |.          ....|.         .                      ...| .|..||  . |.|.     .... ..  
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPW

I
.
F
Pkinase_Tyr AqueK644.AA Pkinase_Tyr 1091-1220 25 6.6e-12 40.95 Pfam 1-144 (270) Show / Hide 
Range on Protein: 1091-1220
Range on HMM: 1-144/270
Sequence Identity: 25% (38 aa)

ITMTEVVLGKGGWGEVKVAGFR------GLKVAAKCLYEVIISPYN--IGTFSREMNIASKI-RHPNLLQFIGATT-EGNP---IILTELMPT-SLRKEL
||. .. ||.|  |||. .  .      ...|| |.|     .. .  .  | ||..| ... .|||.....|. | .| |   .| .|.||  .|.. |
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ESG-----GVAYPAILSISLDVACALNYLHLFKPHPILHRDVSSANVLL
 .       .  . .|......|....||.  .   . |||.   |.|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV
Kinase AqueK644.AA LISK 1097-1155 29 4.5e-10 28.71 In-house 1-64 (296) Show / Hide 
Range on Protein: 1097-1155
Range on HMM: 1-64/296
Sequence Identity: 29% (19 aa)

VLGKGGWGEVKVAGFR--GLKVAAKCLY---EVIISPYNIGTFSREMNIASKIRHPNLLQFIGA
..|||. |.|     |  |  .| | .    .. . | .. .. ||. .  ..|||| .||.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGV
Kinase AqueK644.AA LISK 1187-1267 30 6.2e-07 18.35 In-house 104-177 (296) Show / Hide 
Range on Protein: 1187-1267
Range on HMM: 104-177/296
Sequence Identity: 30% (26 aa)

LSISLDVACALNYLHLFKPHPILHRDVSSANVLLQIT-GGTWKAKVSDYGTVSLQPLARTSNPGN----PVYSAPESPYPNQHSPA
..|.||.||.. |||  .   |.|||  | |.|. .   . |..|| | |      .||. .  |    .  . .||. |.  ...
VKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFG------FARMMDCENNSPCNMPREDESD-PC--MDN
Kinase AqueK644.AA LISK 1269-1281 53 0.004028 5.76 In-house 221-233 (296) Show / Hide 
Range on Protein: 1269-1281
Range on HMM: 221-233/296
Sequence Identity: 53% (7 aa)

DVFSYGVLLIEMV
||||.|..|.|..
DVFSFGIVLCEII
Kinase AqueK644.AA MLK 1301-1328 21 0.03659 3.46 In-house 264-291 (291) Show / Hide 
Range on Protein: 1301-1328
Range on HMM: 264-291/291
Sequence Identity: 21% (6 aa)

PTLKNLIECCLIENYKDRLAMSDIIKEL
. .|.|...|  .. ..|  .. |...|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK644.AA Dicty4 1301-1330 28 0.055455 2.6 In-house 246-277 (277) Show / Hide 
Range on Protein: 1301-1330
Range on HMM: 246-277/277
Sequence Identity: 28% (9 aa)

PTLKNLIECCLIENYKDRLAMSDIIKE--LNE
| .| ||. |. .. . |  .. ||..  |..
PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase AqueK644.AA HH498 1134-1156 39 0.084677 1.03 In-house 49-71 (284) Show / Hide 
Range on Protein: 1134-1156
Range on HMM: 49-71/284
Sequence Identity: 39% (9 aa)

FSREMNIASKIRHPNLLQFIGAT
| ||  | ..  ||.  ||..|.
FCREVSIMCRLNHPCVVQFVYAC
Kinase AqueK644.AA Pkinase_Tyr 1269-1281 53 1.447269 2.54 Pfam 196-208 (270) Show / Hide 
Range on Protein: 1269-1281
Range on HMM: 196-208/270
Sequence Identity: 53% (7 aa)

DVFSYGVLLIEMV
|| |.|||. |..
DVWSFGVLMWEIF
Kinase AqueK644.AA Pkinase_Tyr 1301-1328 25 4.012393 1.04 Pfam 243-270 (270) Show / Hide 
Range on Protein: 1301-1328
Range on HMM: 243-270/270
Sequence Identity: 25% (7 aa)

PTLKNLIECCLIENYKDRLAMSDIIKEL
. . .|.  |  .. .||  .|.|. .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL