Gene AqueK667 (A.queenslandica)

AqueK667

Species: A.queenslandica
Alias: AqueK667
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: TAK1

Sequence

Name Sequence Type Origin Length Description Download
AqueK667.AA Protein None 951 None Fasta, JSON
AqueK667.kin_dom Protein Kinase Domain None 94 None Fasta, JSON

Protein domain

Protein domains of AqueK667.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK667.AA TAK1 302-394 22 1.4e-21 69.54 In-house 168-284 (284) Show / Hide 
Range on Protein: 302-394
Range on HMM: 168-284/284
Sequence Identity: 22% (27 aa)

RYTAPEV----------------------LRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDT-ETIFEGLNQMANGRRPPLLVG---HPSFVNELLQ
|. ||||                      .|.  | ..| ||. ..|..||...|..|  .....   ... .   .||.|||..      |    .. .
RWMAPEVRELFDFKSNRIIINQPTGFQKVFRCEKY-NMKCDIYSWGIIMWEVISRKHP-YDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMK

KCWNQDPGVRLTSTELVEK
.||...|  | .. | |. 
CCWDDNPEKRPSMQECVKY
Kinase AqueK667.AA TKL 302-395 27 1.3e-20 70.98 In-house 238-364 (364) Show / Hide 
Range on Protein: 302-395
Range on HMM: 238-364/364
Sequence Identity: 27% (35 aa)

RYTAPEVLRGTSYSTEKR---------------DIFNFAITLWEMLARQEPVVTEDDTETI-----FEGLNQMAN-GRRPPLL------------VGHPS
|. |||||||. . |||                |.. |.| |||.|.|..|   ..  . |      | . . .. |.|||.                | 
RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPP

FVNELLQKCWNQDPGVRLTSTELVEKF
 . .|.|.||..||  |.. .|.....
SMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK667.AA MLK 301-395 32 6.4e-17 55.34 In-house 197-291 (291) Show / Hide 
Range on Protein: 301-395
Range on HMM: 197-291/291
Sequence Identity: 32% (32 aa)

VRYTAPEVL---RGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVEKF
... ||||.   |.. || || |.. ... |||||.|..|    .. . .. .    .|| |||.  . |   ..|...||||||. | .. . |...
YAWMAPEVIQQFRCEKYS-EKCDVWSWGVVLWEMLTREVPYK--QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK667.AA Fer 300-396 22 4.7e-14 44.35 In-house 181-283 (283) Show / Hide 
Range on Protein: 300-396
Range on HMM: 181-283/283
Sequence Identity: 22% (24 aa)

PVRYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQE---PV------VTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQ-KCWNQDPGVRLTST
|.|..|||...     ..| |.. | ...||  .. .   |       .|. .....    .   .|...|.  ..|... ...  .||..||  | | .
PIRWLAPETWQTGI-YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQAR---KWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMK

ELVEKFK
|...|.|
EICQKLK
Kinase AqueK667.AA TK 284-395 19 6.6e-13 38.83 In-house 326-486 (486) Show / Hide 
Range on Protein: 284-395
Range on HMM: 326-486/486
Sequence Identity: 19% (32 aa)

PSNW-------HYYDASDAIHNDPVRYTAPEVLRG--------TSYSTEKRDIFNFAITLWEMLARQ-EPVVTEDDT---------ETIFEGLNQM----
|  |       . |  ..     |.|..|||.|..        .   |.| |.. | ...||.. .  ||   . .          . ..| | .     
PM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLC

-------ANGRRPPLLVGHP--------------SFVNELLQKCWNQDPGVRLTSTELVEKF
        .. |.|  .. |               .. .|.|.||. ||  | | ..|.|..
RSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK667.AA Dicty4 303-385 35 7.4e-13 39.38 In-house 183-263 (277) Show / Hide 
Range on Protein: 303-385
Range on HMM: 183-263/277
Sequence Identity: 35% (30 aa)

YTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVV-TEDDTETIFEGLNQMAN-GRRPPLLVGHPSFVNELLQKCWNQDPGVR
..||||... .| .|| | . |.| |||.| ||||     .... ....    .| . |||.    | .  .|.|.||. || .|
WMAPEVMMHQPY-NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRA---VCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHR
Kinase AqueK667.AA HH498 302-395 30 9e-13 36.43 In-house 190-284 (284) Show / Hide 
Range on Protein: 302-395
Range on HMM: 190-284/284
Sequence Identity: 30% (30 aa)

RYTAPEVLR-GTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGR-RPPLLVG----HPSFVNELLQKCWNQDPGVRLTSTELVEKF
|. ||||   .. || .| |.| .|. .|||. |  |          .|    ||. . |||.        |     |.| ||.. |  | .  . | . 
RWMAPEVFSQCQKYS-IKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAE----MAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase AqueK667.AA Dicty5 303-399 30 2.5e-12 38.75 In-house 169-260 (260) Show / Hide 
Range on Protein: 303-399
Range on HMM: 169-260/260
Sequence Identity: 30% (30 aa)

YTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVEKFKKIC
. |.|.  |  | ..| |.. |.| ||||..| ||     |  .  .  .  . | || .    |.    |  ||| | |  | . .| .. |..| 
WMACELFNGQPY-HQKCDVYSFGIVLWEMFTRKEPY----DNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase AqueK667.AA MOS 302-347 41 1.2e-11 34.63 In-house 203-247 (299) Show / Hide 
Range on Protein: 302-347
Range on HMM: 203-247/299
Sequence Identity: 41% (19 aa)

RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETI
.| |||.|.|    |.| ||. |.||.| |..|. |  .||  ...
TYMAPELLCGDTP-TPKADIYSFGITMWQMQTRETPYHGEDCHHVY
Kinase AqueK667.AA DRK 304-337 61 2.5e-11 34.66 In-house 169-201 (258) Show / Hide 
Range on Protein: 304-337
Range on HMM: 169-201/258
Sequence Identity: 61% (21 aa)

TAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEP
|||||||   | ||| |.. ||| |||.. || |
TAPEVLRNQRY-TEKADVYSFAIVLWECVTRQDP
S_TKc AqueK667.AA S_TKc 171-396 20 3.4e-11 -12.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 171-396
Range on HMM: 1-231/231
Sequence Identity: 20% (53 aa)

RVDGSLIGIGSSDRVRFATHEG--RDVAVKY--SILAREHKELEQEKHDNIAVLLGTGP-NERFIIREFAPY---SLETVLHGSYPH--CYTYEYNHVMH
   . .|| |.  .|. ..| .  | ||.|     . || . |.. .|.||  |...   .. ... |...    .| ....   .|  .. .   |. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF

WARQTAVGLEYLHSKGFLCPGIKPSN---------------WHYYDASDAIHNDPV---RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTED
...|.. .|||.||.|..   .||.|                ..        .  .    | |||||   .|...| |.  . ..|.|||... |     
YMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---

DTETIFEGLNQMANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVE--------KFK
. ...|. .               |.. . ...||.. ||  |.|  |. .         . 
QMQMMFKKIG-------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc AqueK667.AA TyrKc 171-395 20 1.1e-10 -50.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 171-395
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

RVDGSLIGIGSSDRVRFATHEGRDVAVKYSILAREHKELEQE---------KHDNIAVLLG--TGP-------NERFIIREFAPY-SLETVLHGSYPHCY
 . |  .| |   .|. .|   ..||||       .... .|         .|.||  |.|  | .          .|. |..|. .|   |. . |.  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

TYEYNHVMHWARQTAVGLEYLHSKGF------------------------LCPGIKPS-----NWHYYDASD-AIHN--DPVRYTAPEVLRGTSYSTEKR
     .  ... | | | ||||||..                        |.  |.       .  ||...     .   |.| .|||...   ..| | 
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT-KS

DIFNFAITLWEMLAR-QEPVVTE----DDTETIFEGLNQMANGRRPPLLV--------GHPSFVNELLQKCWNQDPGVRLTSTELVEKF
|.. | ...||.. . |.|   .     . . ..| .  .. .|.|.            ..   . . ..||. ||  | | .|..|.|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV--KQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK667.AA Pkinase 302-395 20 2.2e-09 34.28 Pfam 176-293 (293) Show / Hide 
Range on Protein: 302-395
Range on HMM: 176-293/293
Sequence Identity: 20% (25 aa)

RYTAPEVLRGTSYSTEKRDIFNFAITLWEMLARQEPVVTEDDTETIFEGLNQMANGRRPPLLVGHP------------------------SFVNELLQKC
.| ||||.|| .| . | |.. . ..|.||| .. |   .. ..      .|| . ...| |  .                         .   ... .|
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

WNQDPGVRLTSTELVEK--F
...||  |.| .....   |
LCKDPKKRPTAEQILQHPWF
Kinase AqueK667.AA TKL 177-276 19 4.5e-09 28.84 In-house 1-152 (364) Show / Hide 
Range on Protein: 177-276
Range on HMM: 1-152/364
Sequence Identity: 19% (32 aa)

IGIGSSDRVRFATHEG----------RDVAVKYSIL---------------------------------AREHKELEQ---EKHDNIAVLLG--TGPNE-
|| |..  |  ... |          .|||||                                      .| .|. .    .|.||  ..|  . |.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RFIIREFAPY-SLETVLHGSYPHCYTYEYNHVMHWARQTAVGLEYLHSKG
             .|. |..|  ||. .||           .. ..||...| |..||||..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMN
Kinase AqueK667.AA MLK 173-274 26 9.1e-09 26.68 In-house 3-142 (291) Show / Hide 
Range on Protein: 173-274
Range on HMM: 3-142/291
Sequence Identity: 26% (37 aa)

DGSLIGIGSSDRVRFATHEGRD-----VAVKYSI---------------LAREHKELEQEKHDN----IAVLLGT---GPNERFIIREFAPY-SLETVLH
    || ||.  |  ..  ..|     ||||                  . .| ..|   .| |    | ...|.    |.. .|. |.... || .|||
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLH

GSYPHCY----------TYEYNHVMHWARQTAVGLEYLHS
|  .. .          .|   |.| || | | |..||||
GARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS
Kinase AqueK667.AA TAK1 238-275 44 7.5e-08 22.5 In-house 85-121 (284) Show / Hide 
Range on Protein: 238-275
Range on HMM: 85-121/284
Sequence Identity: 44% (17 aa)

SLETVLHGSYPHCYTYEYNHVMHWARQTAVGLEYLHSK
||  .|||. |. . |   |.| |..| | |. ||||.
SLHNFLHGAKPKWE-YTHAHAMSWMHQCAQGVAYLHSM
Kinase AqueK667.AA TK 204-277 15 3.8e-05 12.38 In-house 87-261 (486) Show / Hide 
Range on Protein: 204-277
Range on HMM: 87-261/486
Sequence Identity: 15% (27 aa)

REHKELEQEK-----HDNIAVLLG----TGP----------NERFIIREFAPY-----SLETVLHGSYPH------------------------------
.|  |... .     |.||  |.|     .|              |. |..|.     || . |. . |.                              
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

-------CYTYEYNHVMH-----------------------------------WARQTAVGLEYLHSK------GF
       | . | . .                                     ...| | |.||||||      .|
SHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNF
Kinase AqueK667.AA Pkinase_Tyr 300-395 24 0.000316 14.94 Pfam 177-270 (270) Show / Hide 
Range on Protein: 300-395
Range on HMM: 177-270/270
Sequence Identity: 24% (25 aa)

PVRYTAPEVLRGTSYSTEKRDIFNFAITLWEMLA-RQEPVVTEDDTE----TIFEGLNQM-ANGRRPPLLVGHPSFVNELLQKCWNQDPGVRLTSTELVE
|.. .|||...   ..| | |.  | ...||..   ..|       .    . .| ...   .|.| |   . |  . .|...||..||  | | .|..|
PIKWMAPECINYGKFTT-KSDVWSFGVLMWEIFTYGEQP-------TYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHE

KF
..
QL
Kinase AqueK667.AA MOS 372-397 30 0.010093 4.61 In-house 274-299 (299) Show / Hide 
Range on Protein: 372-397
Range on HMM: 274-299/299
Sequence Identity: 30% (8 aa)

ELLQKCWNQDPGVRLTSTELVEKFKK
.| |||| . |  |... .|      
QLIQKCWPKQPEQRPSARQLKHELEM
Kinase AqueK667.AA DRK 373-397 36 0.031943 3.37 In-house 234-258 (258) Show / Hide 
Range on Protein: 373-397
Range on HMM: 234-258/258
Sequence Identity: 36% (9 aa)

LLQKCWNQDPGVRLTSTELVEKFKK
|.. ||| ||  | .  | .|    
LMNDCWNEDPQHRPSMQECLERLEA
Pkinase AqueK667.AA Pkinase 171-278 22 0.033401 8.87 Pfam 1-130 (293) Show / Hide 
Range on Protein: 171-278
Range on HMM: 1-130/293
Sequence Identity: 22% (29 aa)

RVDGSLIGIGSSDRVRFATHEGRD--VAVKYSILAREHKELEQE-------------KHDNIAVLLGTG--PNERFIIREFAPY-----SLETVLH-GSY
 . |. || ||. .|. ..| |    ||||   . .|... .|.             .|.||  |...   ...  .. |...      .| ....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PHCYTYEYNHVMHWARQTAVGLEYLHSKGFL
   |  ..... ....|.. ||||.||.|..
GCFY-FSEWECKFYMYQILRGLEYCHSMGII
Kinase AqueK667.AA Pkinase_Tyr 260-277 44 0.875109 3.28 Pfam 115-132 (270) Show / Hide 
Range on Protein: 260-277
Range on HMM: 115-132/270
Sequence Identity: 44% (8 aa)

HWARQTAVGLEYLHSKGF
....| | |.|||.||..
QMCWQIAKGMEYLESKNC