Gene AqueK680 (A.queenslandica)

AqueK680

Species: A.queenslandica
Alias: AqueK680
External Links:
Annotation:

Classification

Group: TKL
Family: STKR
Subfamily: STKR1

Sequence

Name Sequence Type Origin Length Description Download
AqueK680.AA Protein None 522 None Fasta, JSON
AqueK680.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of AqueK680.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK680.AA Type1 225-506 48 5.4e-172 470.25 In-house 1-290 (290) Show / Hide 
Range on Protein: 225-506
Range on HMM: 1-290/290
Sequence Identity: 48% (142 aa)

ILLGESIGGGRFGQVYVGHYQGERYAVKKFFSKDEQSWFHESDIYNSVNLRHDNILTCFATDMLSNNGVTELWLITQYHPRGSLFEELNRGGLTPETTLK
| . | || ||.| |. |...||. ||| ||| ||.||| | .||. | .||.|||  .| || .|. .|.||||| ||..|||.  |||  |.... |.
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR

FIHSTCRGLAYLHLEITGTQ--GKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNF------NNNVQQGTKRYMPPEVIKGTIDVHSFESFLRADIY
 ..|.. |||.|| ||.|||  ||| .||||||||||.||.. .|||||.|||| . .        .|.. ||||||.|||.  |...  |||. .||||
LAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADIY

SFGLVMWEVCTRCHLEGPLADYALPFQSQVPPDPTLDDMTEFIVGKEVIPEIPETWSNNELLRGMSRVMYECWYHQPTARPSAYYIRKKV
||||||||.. ||   |  .||.||.   || ||. .|| . .  . . | ||  |......|.|...| ||||. |.|| .|  | |  
SFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL
Kinase AqueK680.AA STKR 225-506 44 1e-141 460.49 In-house 1-312 (312) Show / Hide 
Range on Protein: 225-506
Range on HMM: 1-312/312
Sequence Identity: 44% (140 aa)

ILLGESIGGGRFGQVYVGHYQG----ERYAVKKFFSKDEQSWFHESDIYNSVNLRHDNILTCFATDMLSN-NGVTELWLITQYHPRGSLFEELNRGGLTP
| | | || ||.| |. |...|    |  ||| |.| |||||| | .||. ...||.|||  .| || .. .. |..|||| ||..|||.. |.|  ...
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

ETTLKFIHSTCRGLAYLHLEIT--GTQ--GKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNF-------N------NNVQQGTKRYMPPEVIKGTI
.. .. .||...|||.|| ||.  |||  .||..||||||||||||||| ||||||||||. . .        |      .| | ||||||.|||. |..
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

DVHSFES-FLRADIYSFGLVMWEVCTRCHLEG------PLADYALPFQSQVPPDPTLDDMTEFIVGKEVIPEIPETWS-NNELLRGMSRVMYECWYHQPT
..  ||| |.|.|.|..||||||...|| . |      . ..| .||. .|| .|...|| . .. |   |.||..|. |.. .|.|. .| |||.| | 
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARPSAYYIRKKV
|| .|  . | .
ARLTALCVKKTM
Kinase AqueK680.AA Type2 225-506 35 1.8e-89 295.59 In-house 1-315 (315) Show / Hide 
Range on Protein: 225-506
Range on HMM: 1-315/315
Sequence Identity: 35% (111 aa)

ILLGESIGGGRFGQVYVGHYQGE-----RYAVKKFFSKDEQSWFHESDIYNS-VNLRHDNILTCFATDM---LSNNGVTELWLITQYHPRGSLFEELNRG
| | | || |||| |. ......       |||.|   | |||  | |||   ....|.|||  ....       .|  |.||.| .|..||| . | . 
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

GLTPETTLKFIHSTCRGLAYLHLEIT-GTQ---GKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNFNNN--------------VQQGTKRYMPPEV
 .. .. .. ..|. ||||.|| ||. ..|    ||..|||||||||.||||| ||||||||||. .    .                | ||.||| |||
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

IKGTIDVHS-FESFLRADIYSFGLVMWEVCTRCHLEG---PLADYALPFQSQVPPD-PTLDDMTEFIVGKEVIPEIPETWSNNELLR-GMSRVMYECWYH
  |...     ..|...|.|..|||.||. .|| . .   .  .| .||...|    |...|| |  | |   |..|..|.... .  .    . .|| |
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

QPTARPSAYYIRKKV
 . || .|  .   .
DAEARLTAQCVQERM
Kinase AqueK680.AA TKL 231-506 26 4.5e-87 295.58 In-house 1-364 (364) Show / Hide 
Range on Protein: 231-506
Range on HMM: 1-364/364
Sequence Identity: 26% (100 aa)

IGGGRFGQVYVGHYQGER----------YAVKKFFSKD-------------------------EQSWFHESDIYNSVN---LRHDNILTCFATDMLSNN-
|| |.||.|| |...|..           ||||| |..                         |.||| .  ..  .    |||.||. . . .. ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------GVTELWLITQYHPRGSLFEELNRGGLTPETTLKFIHSTCRGLAYLHLEIT--GTQGKPSVAHRDIKSKNILVKNDST--------------C
        . ..|.....|.|.|||.. |.     .. .........||..||| ...  .|  || ..|||.|||||||... |              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

CIADFGLAVNYLNFN---------------------NNVQQGTKRYMPPEVIKGTIDVHS----------FESFLRADIYSFGLVMWEVCTRCHLEGPLA
.|.||||. .  . .                     .. | ||.|.|.|||..|...  .          || . ..|.||||.|.||..|||.      
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR------

DYA-LPFQSQVPPDPTLDDMTEFIVGKEVIPEIPETWSN-------NELLRGMSRVMYECWYHQPTARPSAYYIRKKV
 |. .|. .... || ...| . .. |   |.||..|.|       .  ...|.. | .|| | |..|||.  | |. 
PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK680.AA Pkinase 225-506 21 6.5e-54 190.23 Pfam 1-293 (293) Show / Hide 
Range on Protein: 225-506
Range on HMM: 1-293/293
Sequence Identity: 21% (70 aa)

ILLGESIGGGRFGQVYVGHYQGER--YAVKKFFSKDEQSWFHES-----DIYNSVNLRHDNILTCFATDMLSNNGVTELWLITQYHPRG----SLFEELN
. .|. || | ||.|| .| .|..  .|||..  ..| ||....      |.   .|.|.||.... . .      ....... |.. |    .||. . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

---RGGL--TPETTLKFIHSTCRGLAYLHLEITGTQGKPSVAHRDIKSKNILVKNDSTC----CIADFGLAV---NYLNFNNNVQQGTKRYMPPEVIKGT
   .|..  ....  ...  ..|||.|.| .        .. |||.|. |||..|. ..    .|.|||||    .  |  ...  || .||.||||.  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--

IDVHSFESFLRADIYSFGLVMWEVCTRCHLEGPLADYALPFQSQVPPDPTLDDMTEFIVGKEVIPEIPETWSNNELL----------------RGMSRVM
   .. .   ..|..|.|....|....           .||.... .|. .|.|  .   .. ... .. |.... .                . .  ..
---GGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

YECWYHQPTARPSAYYIRKK--V
. |.   |. ||.|  | .   .
KWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK680.AA TKL-Unique 227-429 26 6.3e-29 99.23 In-house 1-225 (290) Show / Hide 
Range on Protein: 227-429
Range on HMM: 1-225/290
Sequence Identity: 26% (64 aa)

LGESIGGGRFGQVYVGHYQGERYAVKKFFS---KDEQSWF-HESDIYNSVNLR-HDNILTCFATDM----LSNNGVTELWLITQYHPRGSLFEELN----
 ...||.| .|||| | . |. .|.|.|.    .  .. . .|. .  . .|. |.||...... |      .|    . ... | |.||| . |.    
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPN----MCIVMEYCPGGSLYDVLHQNNN

-------RGGLTPETTLKFIHSTCRGLAYLHLEITGTQGKPSVAHRDIKSKNILVKND-----STCCIADFGLAVNYL-----NFNNN------VQQGTK
          |...  .|...   .|. ||| ...     | ..|||.||.|.|| |.         |.||||. .       ..|..      . .|. 
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEP-----P-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF

RYMPPEVIKG---TIDVHSFESFLRADIYSFGLVMWEVCTRC
|.|.|||...   ... .|       |.|||| |.||  ||.
RWMAPEVLRMNFCQYSEKS-------DVYSFGIVLWEIATRK
Kinase AqueK680.AA MLK 225-428 23 8.2e-29 97.14 In-house 1-232 (291) Show / Hide 
Range on Protein: 225-428
Range on HMM: 1-232/291
Sequence Identity: 23% (58 aa)

ILLGESIGGGRFGQVYVGHYQGER-----YAVKKFF-------SKDEQSWFHESDIYNSVNLRHDN----ILTCFATDMLSNNGVTELWLITQYHPRGSL
|.. | || | ||.|. | .....      |||...       ......|  | ...    |.| |    |    ..   ....  .. ....| . |||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGV--CLQPP-CHFCIVMEYCEGGSL

FEELNRG---------------GLTPETTLKFIHSTCRGLAYLHLEITGTQGKP-SVAHRDIKSKNILVKN------DSTCCIADFGLAVNYLNFNNN--
.. |. .                 ...  ... .   ||..||| .      .|  . |||.||.|||. .      . |. |.|||..     ....  
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMCT

---VQQGTKRYMPPEVI-KGTIDVHSFESFL---RADIYSFGLVMWEVCTR
    ..|| ..| |||| .       |..      .|..|.|.|.||. ||
NMMSNAGTYAWMAPEVIQQ-------FRCEKYSEKCDVWSWGVVLWEMLTR
Kinase AqueK680.AA S_TKc 225-510 18 1e-28 102.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 225-510
Range on HMM: 1-231/231
Sequence Identity: 18% (55 aa)

ILLGESIGGGRFGQVYVGHYQG--ERYAVKKFFSKDEQSWFHESDIYNSVNLRHDNILTCFATDMLSNNGVTELWLITQYHPR--GSLFEELNRGG----
  ... || | ||.|| ..  .  ...|.|.      ..   | .|  .   .|.|| ... .        ..|.... | .   |.||. . . |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTPETTLKFIHSTCRGLAYLHLEITGTQGKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNFNNNVQQGTKRYMPPEVIKGTIDVHSFESFL--
   ... .. .... .|..|.|.|        .  . |||.|  |||. .  .  |.|||||  .     . . ||  ||.|||.          ..   
RFPFPE-HARFYMYQICCALEYCH-------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----------GYGKC

RADIYSFGLVMWEVCTRCHLEGPLADYALPFQSQVPPDPTLDDMTEFIVGKEVIPEIPETWSNNELLRGMSRVMYECWYHQPTARPSAYYIRK-----KV
..|..|.| ...| .... .     .... |.  .                                . .   .  |.   |. ||.|  . .     | 
KCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

DKIA
.   
HPWF
Kinase AqueK680.AA STE 226-459 19 5.1e-26 88.94 In-house 1-334 (359) Show / Hide 
Range on Protein: 226-459
Range on HMM: 1-334/359
Sequence Identity: 19% (69 aa)

LLG-ESIGGGRFGQVYVGHYQ-----------------GERYAVKKF--------------------FSKDEQSWFHESDIYNSVN-LRHDNILTCFATD
. | | || | ||.|| . .                  ||..|.|.                     .....|.  .| .| .  |   |.|| ... . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

MLSN--NGV-TELWLITQYHPRGSLFEELNR--GGLTP------------ETTL-KFIHSTCRG-LAYLHLEITGTQGKPSVAHRDIKSKNILVKNDSTC
.  .  ..  .|||..  | . ||| . ...  | . |            |. . ........| |.|||           . |||||. |||.     .
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--------IIHRDIKPANILL-----V

CIADFGLAVNYLN------------------FNNNVQQGTKRYMPPEVIKGTI----DVHSFESFLRADIYSFGLVMWEVCTRCHLE---GPL-ADYALP
 ..|||.. .  .                   ..|   ||  .| ||||..      . ...    ..||.|.|....| .| ..      |. | .. |
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT----KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIP

FQ--------------SQVPPDPTL---------------------DDMTEFI
|                . || |.                      ... .||
FNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFI
Kinase AqueK680.AA TK 225-429 14 1.3e-19 61.74 In-house 1-391 (486) Show / Hide 
Range on Protein: 225-429
Range on HMM: 1-391/486
Sequence Identity: 14% (57 aa)

ILLGESIGGGRFG---QVYVGHYQGER-----------------------------YAVKKFFSKDEQSWFH------------------ESDIYNSVNL
| ||. .| | ||   .|| | ..|..                              ...|  . ..|  |.                  |  . ..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHDNILTCFATDMLSNN--------GVTELWLITQYHPRGS----LFEELN--RGG--------------------------------------------
.|.||. ...  . . .        .   ..... | | |.    | . |   |..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTPETTLKFIHSTCRGLAYLHLE---ITGTQGKPSVAHRDIKSKNILVKNDST-----------CCIAD
                               ||... | . .  ..|..|||            . . |||.   |.|| .. .           | |||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF-----IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIAD

FGLA------VNYLNFNNNVQQGTK------------------------------RYMPPEVIKGTI-------DVHSFESFLRADIYSFGLVMWEVCTR
|||.            ..     ..                              |.|.||.... .        ... .|    |..||| .|||..|.
FGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKS----DVWSFGVLMWEIFTY

C
.
G
Kinase AqueK680.AA CAMK 230-400 15 2.5e-19 58.26 In-house 1-294 (425) Show / Hide 
Range on Protein: 230-400
Range on HMM: 1-294/425
Sequence Identity: 15% (47 aa)

SIGGGRFGQVYVGHYQ-G-------------ERYAVKKFF-------------------------------SKDEQSWFHESDIYNSVN-----LRHDNI
 .| |.||.|. .                  ...|.|                                   ||... ..| .| ....     |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LTCFA-----------TDML-SNNG-----VTELWLIT---QYHPRG----SLFEELNR----------------GGLTPETTLKFIHSTCRGLAYLHLE
. ..            .|   . .       .......    | . |     ||. . .                | .| . . ....  | ...|.|  
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

ITGTQGKPSVAHRDIKSKNILVKNDS-----------------TCCIADFGLAVNYLNFNNNV-------------------------QQGTKRYMP-PE
         ..|||.|  |||. ...                 .  |.|||.|  .   .||                          . ||  ||. ||
--------NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

VIKG
|..|
VLNG
Kinase AqueK680.AA RAF 225-429 26 7.1e-18 54.26 In-house 1-218 (282) Show / Hide 
Range on Protein: 225-429
Range on HMM: 1-218/282
Sequence Identity: 26% (61 aa)

ILLGESIGGGRFGQVYVGHYQGE----RYAVKKFFSKDEQS-WFHESDIYNSVNLRHDNILTCFATDMLSNNGVTELWLITQYHPRGSLF----EELNRG
. ... || |.|| || ||. |.    .  |..   .. |   |    .    . ||.|||  .     |.     .  .||.    ||.    . . | 
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMG--YMSKPQTNTYAIVTQWCEHSSLYHHIHVQETRE

GLTPETTLKFIHSTCRGLAYLHLEITGTQGKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNFN----NNVQQGTKR--YMPPEVIK-------GTI
 .   ...     .| |. |||        . .. |||.||.||. ..| |  | ||||.      .      ..| |    .| ||||.       | .
KFDMHWLIDISRQVCQGMDYLH--------AKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDV

DVHSFESF-LRADIYSFGLVMWEVCTRC
       .    |.|||| ||.|. ||.
LMQDENPYSFQSDVYSFGIVMYELMTRH
Kinase AqueK680.AA TyrKc 225-506 23 2.4e-15 25.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 225-506
Range on HMM: 1-280/280
Sequence Identity: 23% (75 aa)

ILLGESIGGGRFGQVYVGHYQGERYAVKKFF-SKDEQSWFHESDIYNSVNL--RHDNILTCFATDMLS--NNGV---TELWLITQYHPRGSLFEEL--NR
| ||. .| | ||.|| |..  .  |||.   .. ..   .|  |    .|  .|.||. ...  . .  |        |.... | | |.| . |  .|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMC--KLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKHR

GGLTPETTLKFIHSTCRGLAYLHLEITGTQGKPSVAHRDIKSKNILVKNDSTCCIADFGLAVNYLNF--------NNNVQQ--GTK-----RYMPPEVIK
. |.... |.| .  ..| .|||           . |||.   |.||... |. |.||||. .  .            ...  |.|     | |.||.| 
PKLCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

GTIDVHSFESFLRADIYSFGLVMWEVCTRCHLEGPLADYALPFQS---QVPPDPTLDDMTEFIVGKEVIPEIPETWSNNE-----LLRGMSRVMYECWYH
    . ...|    |..||| .|||..|..         . |      |   . . ... |..   .  |  |.     .         | ..| .|| .
-NYGKFTTKS----DVWSFGVCMWEIFTYG---------QQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHE

QPTARPSAYYIRKKV
.|  ||.   |... 
DPEDRPTFSEIHECF
TGF_beta_GS AqueK680.AA TGF_beta_GS 195-223 48 3.1e-11 40.0 Pfam 1-29 (29) Show / Hide 
Range on Protein: 195-223
Range on HMM: 1-29/29
Sequence Identity: 48% (14 aa)

NDLTSFLQMSFTSGSGAGMPFLVKRTIAR
 .. ...... ||||| |.|.||.|||||
KTMQDMMEDFCTSGSGSGLPLLVQRTIAR
GS AqueK680.AA GS 195-225 45 3.5e-10 41.06 SMART 1-31 (31) Show / Hide 
Range on Protein: 195-225
Range on HMM: 1-31/31
Sequence Identity: 45% (14 aa)

NDLTSFLQMSFTSGSGAGMPFLVKRTIARSI
 .. . .... ||||| | |.||.||.|| |
KTMHDMMEDTCTSGSGSGLPLLVQRTVARQI
Kinase AqueK680.AA Pkinase_Tyr 351-375 48 1.2e-05 19.7 Pfam 134-158 (270) Show / Hide 
Range on Protein: 351-375
Range on HMM: 134-158/270
Sequence Identity: 48% (12 aa)

HRDIKSKNILVKNDSTCCIADFGLA
|||.  .|.||... .. |.|||||
HRDLAARNCLVTENNVVKICDFGLA
Kinase AqueK680.AA TK 481-506 23 0.000419 8.81 In-house 461-486 (486) Show / Hide 
Range on Protein: 481-506
Range on HMM: 461-486/486
Sequence Identity: 23% (6 aa)

MSRVMYECWYHQPTARPSAYYIRKKV
. ..| .|| ..|  ||.   .... 
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK680.AA TKL-Unique 485-506 36 0.008501 5.91 In-house 269-290 (290) Show / Hide 
Range on Protein: 485-506
Range on HMM: 269-290/290
Sequence Identity: 36% (8 aa)

MYECWYHQPTARPSAYYIRKKV
. .|| |.|. |||   |... 
IQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK680.AA Pkinase_Tyr 414-429 50 0.016964 9.08 Pfam 196-211 (270) Show / Hide 
Range on Protein: 414-429
Range on HMM: 196-211/270
Sequence Identity: 50% (8 aa)

DIYSFGLVMWEVCTRC
|..||| .|||..|..
DVWSFGVLMWEIFTYG
Kinase AqueK680.AA Pkinase_Tyr 483-506 29 0.024158 8.56 Pfam 247-270 (270) Show / Hide 
Range on Protein: 483-506
Range on HMM: 247-270/270
Sequence Identity: 29% (7 aa)

RVMYECWYHQPTARPSAYYIRKKV
..| .|| ..|  ||.  .|. . 
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase AqueK680.AA Pkinase_Tyr 225-246 45 0.043351 7.7 Pfam 1-22 (270) Show / Hide 
Range on Protein: 225-246
Range on HMM: 1-22/270
Sequence Identity: 45% (10 aa)

ILLGESIGGGRFGQVYVGHYQG
| .|. .| | ||.|| |.. |
ITFGKKLGEGAFGEVYKGTWKG
Kinase AqueK680.AA RAF 481-508 35 0.062109 1.71 In-house 255-282 (282) Show / Hide 
Range on Protein: 481-508
Range on HMM: 255-282/282
Sequence Identity: 35% (10 aa)

MSRVMYECWYHQPTARPSAYYIRKKVDK
| | | .||  |.  ||.   | |... 
MHRLMEDCWKFQREERPLFQQILKRITV
Kinase AqueK680.AA MLK 479-506 28 0.093964 2.02 In-house 264-291 (291) Show / Hide 
Range on Protein: 479-506
Range on HMM: 264-291/291
Sequence Identity: 28% (8 aa)

RGMSRVMYECWYHQPTARPSAYYIRKKV
..... | .||   |  |||  .| .. 
EHWKKLMKQCWNQDPHKRPSFRQIVQHL