Gene AqueK690 (A.queenslandica)

AqueK690

Species: A.queenslandica
Alias: AqueK690
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
AqueK690.AA Protein None 447 None Fasta, JSON
AqueK690.kin_dom Protein Kinase Domain None 127 None Fasta, JSON

Protein domain

Protein domains of AqueK690.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK690.AA TKL 219-394 19 4.7e-24 83.52 In-house 110-364 (364) Show / Hide 
Range on Protein: 219-394
Range on HMM: 110-364/364
Sequence Identity: 19% (52 aa)

EGNPIILTELM-PSSLRKELETGLPLPYPAILSISLDVACALNYLHLFKP-----HPIIHRDISSGNVLLQPTSH--------MGIGWRAKVSDYGSANL
.|.. | .|..   ||.  |        . .....||.|...||||  .|      ||||||. | |.|.    .          . |..|..|.| .  
WGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRF

QNLIA--------------------TTENPG-NRVYSAPEA--GNP--------------REHSPAMDVFSYGVLLIEMSISAIPQ--PGNR--------
 .                       || ... .  . |||.  |..              .| |...||.|.|..| |.    .|   ....        
MSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPF

----RQDINSIRR--------------------AGFKGLVQRCVMDNYELRPKMSDIINEL
     ....  .|                     ..| | |.|   . | || ...|. .|
EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK690.AA Dicty5 239-346 32 2.9e-13 42.02 In-house 97-196 (260) Show / Hide 
Range on Protein: 239-346
Range on HMM: 97-196/260
Sequence Identity: 32% (35 aa)

TGLPLPYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYG-SANLQNLIATTENPGNRVYSAPEAGNPREHSPAMDVF
|| |. |. .|.. .|.| .. .||      |||||. | |.|.         | .|. |.| | .  |    | . |   . |.|  | .      ||.
TGQPIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMNFLITEN------WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVY

SYGVLLIEM
|.|. | ||
SFGIVLWEM
Kinase AqueK690.AA MLK 248-346 32 6.9e-13 41.16 In-house 126-229 (291) Show / Hide 
Range on Protein: 248-346
Range on HMM: 126-229/291
Sequence Identity: 32% (34 aa)

ILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQP--TSHMGIGWRAKVSDYGSAN-LQNLIA-TTENPGNRVYSAPEA---GNPREHSPAMDVFSYG
.....|..| ...|||  .|.||||||. | |.|.      .|. |  .|..| | .  ...  .  . |.|.  . |||.         | . ||.|.|
AMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHG-TLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWG

VLLIEM
|.| ||
VVLWEM
Kinase AqueK690.AA HH498 246-346 37 1.9e-12 35.37 In-house 121-219 (284) Show / Hide 
Range on Protein: 246-346
Range on HMM: 121-219/284
Sequence Identity: 37% (39 aa)

PAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSANLQNLIAT---TENPGNRVYSAPEAGN-PREHSPAMDVFSYGV
. .. ||.|||   ||||   .|||||||  | |.|.      |.   |.| |.|     . .     |  |||  . |||        |   |||||. 
QSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH---EDGH---AVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAM

LLIEM
 . ||
CIWEM
Kinase AqueK690.AA TKL-Unique 231-346 25 1.1e-11 37.63 In-house 85-221 (290) Show / Hide 
Range on Protein: 231-346
Range on HMM: 85-221/290
Sequence Identity: 25% (35 aa)

SSLRKELE----------TGLPLPYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSH-MGIGWRAKVSDYGSANLQNLIATTENP-----
.||.. |             ..|..  .... .|.| ...|||  .|  |||||. | |.|.  ...     |..|..| | . ... | .. |      
GSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLV--DNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGT

------GNRVYSAPEAGNP--REHSPAMDVFSYGVLLIEM
      |.  ..|||  .      |   ||.|.|. |.|.
RNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI
S_TKc AqueK690.AA S_TKc 168-395 17 2e-11 -9.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 168-395
Range on HMM: 1-231/231
Sequence Identity: 17% (45 aa)

FTKVRM----EYAATFDAIDKV---------IASDTPSLAELRTFLRRGHGYCKLTSQCERATREGNPIILTELMPS---SLRKELETGLP------LPY
....|      ..  . ...|          |      . |..   . .| .      . .    ..  . .|...    .|.. ..   .      .| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

PAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSANLQNLIATTENPGNRVYSAPEAGNPREHSP-AMDVFSYGVLLI
  . ..   ..|||.|.|  .   |||||.   |.||          . |..| |.| .      |   | . | |||      ... . |. | |..|.
-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMSISAIPQPGNRRQDINSIRRAGFKGLVQRCVMDNYELRPKMSDIIN--------ELT
||     | | .  . .. |.   .| ....|   . | ||   .. .        .  
EMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase AqueK690.AA Pkinase 217-346 21 2.4e-11 41.22 Pfam 70-205 (293) Show / Hide 
Range on Protein: 217-346
Range on HMM: 70-205/293
Sequence Identity: 21% (31 aa)

TREGNPIILTELMPS-----SLRKELE--TGLPL--PYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSAN---L
...... . .|...      .|   ..   . ..  ..  . .. . ....|.|.|      |||||. . |.|.  . | .   . |..| |.|    .
EDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY

QNLIATTENPGNRVYSAPEAGN-PREHSPAMDVFSYGVLLIEM
 |   .|   | . | |||  .  ....|. |..|.|..|.||
-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEM
Kinase AqueK690.AA CZAK 249-346 28 7.1e-11 35.87 In-house 108-215 (279) Show / Hide 
Range on Protein: 249-346
Range on HMM: 108-215/279
Sequence Identity: 28% (31 aa)

LSISLDVACALNYLHL-FKPHPIIHRDISSGNVLLQPTSH-------MGIGWRAKVSDYGSANLQNLIAT--TENPGNRVYSAPEAGNPREHSPAMDVFS
... .|.|   ||||  .|| ||.||| || |.||                  .|..|.|   .    ..  |   |   . |||       ..  ||.|
WNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYTEKVDVYS

YGVLLIEM
.| .| ..
FGMILWCI
Kinase AqueK690.AA TK 217-346 14 1.2e-09 27.72 In-house 125-387 (486) Show / Hide 
Range on Protein: 217-346
Range on HMM: 125-387/486
Sequence Identity: 14% (38 aa)

TREGNPIILTELMP-SS----LRKELETGLP---------------------------------------------------------------------
. .. ..|..|.||  .    ||. | .  |                                                                     
VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQW

-------LPYPAILSISLDVACALNYLHLFKPHPI----IHRDISSGNVLLQPTSHM-----GIGWRAKVSDYGSAN-----LQNLIATTENPGNRV---
       |. .  | .....||.. |||  .        .|||.   |.|.    .      | |  .|..|.| .      |   |   ..   .    
CLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYG

----------------------------YSAPEAGN---------PREHSPAMDVFSYGVLLIEM
                            . |||. |          . .... ||.|.|||. |.
TGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase AqueK690.AA IRAK 249-282 48 9.8e-09 27.25 In-house 112-146 (317) Show / Hide 
Range on Protein: 249-282
Range on HMM: 112-146/317
Sequence Identity: 48% (17 aa)

LSISLDVACALNYLHLFKPH-PIIHRDISSGNVLL
.||..  ||....|| . |  ||||.||.| |.||
CSICWGTACGIQFLHQNHPCTPIIHGDIKSANILL
Kinase AqueK690.AA STE 224-346 23 1.8e-08 26.18 In-house 114-261 (359) Show / Hide 
Range on Protein: 224-346
Range on HMM: 114-261/359
Sequence Identity: 23% (38 aa)

ILTELMP-SSLRKELE----TGLPLP----------YPAILSISLDVACA-LNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSAN-LQN
|  |.|.  ||.. ..    .| ||.           . |  |  ..  . |.|||  .   |||||| ..|.||           .| .| | .  |..
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----------VKLCDFGVCGQLTD

LIA-----------------TTENPGNRVYSAPEAGNP------REHSPAMDVFSYGVLLIEM
 .|                 ..   |   . |||  ..       ...   |. | | ..|||
SMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase AqueK690.AA TK-Unique 242-346 24 4.9e-08 23.93 In-house 127-232 (294) Show / Hide 
Range on Protein: 242-346
Range on HMM: 127-232/294
Sequence Identity: 24% (28 aa)

PLPYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSA-----NLQNLIATTENPGNRVYSAPEAGN--PREH-SPA
|. .   ...  ..||...||.   .. |.|||... ||||.       . ..|..|.| |     | ..   .....    . |||.     . . .. 
PISPKDLYHFAWQIACGMEYLASQ-RKKIVHRDLCARNVLLTE------DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTK

MDVFSYGVLLIEM
 || |.|||. |.
SDVWSFGVLMWEI
TyrKc AqueK690.AA TyrKc 161-394 19 1.4e-07 -100.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 161-394
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

IHLDIV----NFTKVRMEYAATFDAIDKVIASDTPSLAELRTFLRRGHGY-------CKLTSQCERATRE----GNPIILTELMPS-SLRKELETGLP-L
|.|. .    .| .|.   .   .   |.. .|.  .....  .|  . .        .|   |    |     . . |..|.||  .|.. |    | |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

PYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLLQPTSHMGIGWRAKVSDYGSANLQ----------NLIATTENPGNR--V---YSAPEAGNPR
. .  ||.....||  .|||    ...||||.   |.|.          ..|.|| | .               . ..|  | .  .     |||. | .
CMKDLLSFCWQIACGMEYLHS---KNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

EHSPAMDVFSYGVLLIEM-SISAIPQPG------------------NRRQDINS--------IRRAGFKGLVQRCVMDNYELRPKMSDIINEL
. ... ||.|.||.. |. .  . | ||                  .|.    .           . .. . ..| . . | || .|.|. ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK690.AA Pkinase_Tyr 217-282 25 2e-06 22.7 Pfam 74-144 (270) Show / Hide 
Range on Protein: 217-282
Range on HMM: 74-144/270
Sequence Identity: 25% (19 aa)

T-REGN--PIILTELMPS-SLRKELET----GLPLPYPAILSISLDVACALNYLHLFKPHPIIHRDISSGNVLL
| ...   ..| .|.||  .|.. | .    . ||. . .|......|....||.  .   .||||.   |.|.
TDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLV
Kinase AqueK690.AA TK 372-394 34 0.009028 4.26 In-house 464-486 (486) Show / Hide 
Range on Protein: 372-394
Range on HMM: 464-486/486
Sequence Identity: 34% (8 aa)

LVQRCVMDNYELRPKMSDIINEL
| |.|   . | || .|.. ..|
LMQQCWHYDPEDRPTFSQLHEQL
Kinase AqueK690.AA MLK 367-394 25 0.017686 4.57 In-house 264-291 (291) Show / Hide 
Range on Protein: 367-394
Range on HMM: 264-291/291
Sequence Identity: 25% (7 aa)

AGFKGLVQRCVMDNYELRPKMSDIINEL
...| | ..|  .. . ||... |. .|
EHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase AqueK690.AA TKL-Unique 372-394 34 0.039432 3.53 In-house 268-290 (290) Show / Hide 
Range on Protein: 372-394
Range on HMM: 268-290/290
Sequence Identity: 34% (8 aa)

LVQRCVMDNYELRPKMSDIINEL
| |.|  .. . ||  ..||..|
LIQQCWHHDPSQRPSFDEIIHRL
Kinase AqueK690.AA IRAK 321-345 29 0.152541 1.44 In-house 190-216 (317) Show / Hide 
Range on Protein: 321-345
Range on HMM: 190-216/317
Sequence Identity: 29% (8 aa)

APEAGN--PREHSPAMDVFSYGVLLIE
.||. .   .. ..  ||.| |. | |
PPEFIRDPQGQLTKKTDVYSFGIVLLE
Kinase AqueK690.AA Pkinase_Tyr 335-346 58 1.204569 2.81 Pfam 196-207 (270) Show / Hide 
Range on Protein: 335-346
Range on HMM: 196-207/270
Sequence Identity: 58% (7 aa)

DVFSYGVLLIEM
|| |.|||. |.
DVWSFGVLMWEI
Kinase AqueK690.AA Pkinase_Tyr 384-394 45 4.15111 0.99 Pfam 260-270 (270) Show / Hide 
Range on Protein: 384-394
Range on HMM: 260-270/270
Sequence Identity: 45% (5 aa)

RPKMSDIINEL
|| .|.|...|
RPTFSEIHEQL