Gene NME7a (Mouse)

NME7a

Species: Mouse
Alias: NME7a
External Links:
Annotation:

Classification

Group: NDK
Family: NDK

Sequence

Name Sequence Type Origin Length Description Download
NME7a.AA Protein None 395 None Fasta, JSON
NME7a.NA RNA None 1711 None Fasta, JSON
NME7a.kin_dom Protein Kinase Domain None 133 None Fasta, JSON

Protein domain

Protein domains of NME7a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
NDK NME7a.AA NDK 110-248 42 8.4e-71 242.45 SMART 1-142 (142) Show / Hide 
Range on Protein: 110-248
Range on HMM: 1-142/142
Sequence Identity: 42% (61 aa)

KEKTLALIKPDAV--SKAGEIIEMINKSGFTITKLRMMTLTRKEAADFHV-DHHSRPFYNELIQFITSGPVIAMEILRDDAICEWKRLLGPANSGLSRTD
.|.|...||||||   . ||||... ..||.|....||.||...|. ... .|...||.|.|..|.|||||.||.. ...||..|....|| |..  .  
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

APGSIRALFGTDGVRNAAHGPDTFASAAREMELFFPSSGGCG
|||.||. ||||  ||. || | ..||.||....||.|  |.
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK NME7a.AA NDK 111-246 39 7.6e-57 199.97 Pfam 1-140 (140) Show / Hide 
Range on Protein: 111-246
Range on HMM: 1-140/140
Sequence Identity: 39% (55 aa)

EKTLALIKPDAV--SKAGEIIEMINKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYNELIQFITSGPVIAMEILRDDAICEWKRLLGPANSGLSRTDAP
|.|...||||||   . ||||... . ||.|  ..||.||| .|  .  .|  .||...|..|.|||||.|| . ...|| .|  ..|. |   ..  ||
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKGKPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EAP

GSIRALFGTDG--VR-NAAHGPDTFASAAREMELFFPSSGG
|.||. |...    | |. || |  .||.||. ..|| .  
GTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI
DM10 NME7a.AA DM10 22-110 20 7.1e-40 139.7 SMART 1-126 (126) Show / Hide 
Range on Protein: 22-110
Range on HMM: 1-126/126
Sequence Identity: 20% (26 aa)

QSERFAFIAEWYDPNA------SLLRRYELLFYPTDGSVEMH--DVKNR-----RTFLKRTKYED------------------------LRLEDLFIGNK
......|.|.|.|...      ...||.....|. |...|..  .|.|      ..||.|....                         .. .|...|..
DKQVLCFDAYWDDDVCMKYHEYYRIRRFKIHYYLEDDTIEIFEPHVRNSGIDQFGCFLRRQRVPKPCRENQKYFYCCDQEMYPNDDPEYYHWKDFNVGTT

VNVFSRQLVLIDYGDQYTARQLGSRK
.|||.||....|.|||.|.... ...
INVFGRQFHIYDCGDQFTRNYMEQCY
NDK NME7a.AA NDK 256-394 32 5.1e-46 160.11 SMART 1-142 (142) Show / Hide 
Range on Protein: 256-394
Range on HMM: 1-142/142
Sequence Identity: 32% (46 aa)

TNCTCCIIKPHAISEGMLGKILIAIRDACFGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFCGPADPEIARHL
...|...|||.|.. |  |.|.  . .. | . |..|. |.....||.|.|..   . .||.|.  .|||.|| ...  |  ||.|...|| .||.... 
MERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMQLTKEQAEEHYAVEHKGKPFFNDLVEFMTSGPVVAMVWEGENAIKTWRTMMGPTNPEVPKEA

RPETLRAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKIL---D
 |.|.|. ||... .|.||. | ||.   |..|.|.     .
APGTIRGDFGTDIGRNIVHGSDSPESAEREIAYWFPESEICE
NDK NME7a.AA NDK 257-392 31 2.1e-26 98.65 Pfam 1-140 (140) Show / Hide 
Range on Protein: 257-392
Range on HMM: 1-140/140
Sequence Identity: 31% (45 aa)

NCTCCIIKPHAISEGMLGKILIAIRDACFGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFCGPADPEIARHLR
  |  .|||.|.  |  |.|.  . .. | . |. | .|.|. .||.|.. ||    ..|.|.  .|||.||. ..  |  |..||..|. .|. |.   
ERTFIMIKPDAVQRGLIGEIISRFERKGFKIVAMKMMHLTREQAEEHYAEHKG-KPFFPDLVEFMTSGPVVAMVWEGENAIKKWREMMGATNPAEAK-EA

PETLRAIFGKTK--VQ-NAVHCTDLPEDGLLEVQYFFK---I
| |.|. |...      |.||. | ||.   |  ..|.   |
PGTIRGDFAVSIYPGRRNVVHGSDSPESAEREIAFWFPPEEI