Gene NDR1_a-2 (S.moellendorffii)

NDR1_a-2

Species: S.moellendorffii
Alias: NDR1_a-2
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
NDR1_a-2.AA Protein None 527 None Fasta, JSON
NDR1_a-2.NA RNA None 1584 None Fasta, JSON
NDR1_a-2.kin_dom Protein Kinase Domain None 305 None Fasta, JSON

Protein domain

Protein domains of NDR1_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NDR1_a-2.AA NDR 124-428 50 2.7e-193 602.26 In-house 1-350 (350) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-350/350
Sequence Identity: 50% (175 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVD--SNYIVKLYCSFQDDEYLYLIMEYLPGGDMMT---LLMRKDT
|| ..|||.||||||.|.|.|.|| .||||...||||... || ||.|||  .||.|  ....||||.||||. ||||.|||.|||||||   |||..|.
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP------LDCSN----------FPMLRENDLSTDKNQRDGLDANRR-T
.||..|.||||| |.||||.||  ||||||||||.|.|| ||.||.|||||.       .  .           |   . .........    | ..  .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

SSPAPRRT---QQEQLQH-----------WQRNRRMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTH
|.| .. .    |.. |            |..||| |||||||||||.||||... .||...|||||||.|.||||||.|||.||.|  ||.|| ||.. 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----KFPDEAKLSVEARDLMSRLLC-GVDQRLGT--KGTHEIKSHSWF
.      || ||.||.|| ||  ||.|   |.|||   || .|||||..|
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase NDR1_a-2.AA AGC 124-428 31 6.4e-179 467.4 In-house 1-395 (395) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-395/395
Sequence Identity: 31% (135 aa)

FELLTIIGRGAFGEVRLCREK------STGYVYAMKKLKKSE---MLRRGQVEHVKAE------------RNLLAEVD----------SNYIVK-LYCSF
||.|..||.|.||.|.|.|.|      .|| .||||.|||..   .... .|||...|            || |....          . .||| |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDEY--LYLIMEYLP---------GG-DMMTLLM---RKDTLTENEAKFYIAE-------AVLAIESIHK-HKYIHRD-IKPDNLLLDKNGHLKLSDFG
||...  ||..|||.|         || .... |.   .. ...|..|.||.||        |||.|..|. ...|||| .||.|.|||..||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKPLDC------------------SNFPMLRENDLSTDKNQRDGLDANRRTSSPAPRRTQQEQLQHWQRNR-----------RMLAYSTVG--TPDYIA
||| .                    ...    . ... . |                   . . ...||||.           | .... .|  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKY-Q-KS-NMD-T-N-------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMA

PEVLLKKGYGMECDWWS--LGAILYEMLVGFPPFYSDE----------PMFTCRKIV------NWRTHLKFP------DEAKLSVEARDLMSRLLC-GVD
||.|    || .|||||  ||...||||.| ||||.|.          || .  ||       ||. .. ||      .. ..|.||.||...|||   .
PEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPE

QRLGTK-------GTHEIKSHSWF
.|||..       |. |||.| ||
KRLGCGGNDFGDKGAEEIKNHPWF
Kinase NDR1_a-2.AA MAST 124-428 33 9.60000000001e-123 377.01 In-house 1-337 (337) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-337/337
Sequence Identity: 33% (122 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQD--DEYLYLIMEYLPGGDMMTLLMRKD-TLT
|| . .|..||.| | | . |.|.  .|||..... .... ||..|..||| |.... ...||...|||   ..||...|||. |||  .||     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP--LDCSNFPMLRENDLSTD---KNQRDGLDANRRTSSPAPRRTQQEQLQ
|..||.|||| ||..| .|..  .|||.||||.|.|.|||.|| |||| |   .| ..  .. |   .|.   |                    ..  . 
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTT--NHYEGYFNTNIFGK--------------------NHFNEY

HWQRNRRML-------------------------------------AYSTVGTPDYIAPEVLLKKG-YGMECDWWSLGAILYEMLVGFPPFYSDEPMF-T
| |.| ...                                       . .||||||||||.|..| ||   ||||.| |.|| ||| |||  |.|   .
HIQKNYQQFQQDFGINGNTNKNQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMI

CRKIVNWRTHLKFPDE------AKLSVEARDLMSRLLCGVD--QRLGTKGTHEIKSHSWF
  .|.|   .. .|.|       ..| ||.||...||  ..  .|||..| .|||.|  |
FQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQ-PNPKKRLGANGADEIKQHPFF
Kinase NDR1_a-2.AA MAST 124-428 37 7.6e-118 381.57 In-house 1-334 (334) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-334/334
Sequence Identity: 37% (125 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTENE
||   .|..||.| | | . |.|.  .|||..|||.|... .|..|..||| ||.......||...||| ..||...|||. |||  .||    .. |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKP--------LDCSNFP--MLRENDLSTDKNQRDGLD---------ANRRTSSP
||.|||| ||..| .|.|  .|||.||||.|.|.||| || |||| |         .. ...|  ..     ...|||.|             .   .. 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

APRRTQQEQLQHWQRNRRMLAYSTVGTPDYIAPEVLLKKG-YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWR---THLKFP----DEAKLS
     .|.|.|    .  .   . .||||||||||.|..| .|.  ||||.| |.|| ||| |||  |.|  .  .|.| .   . . ..    |. ..|
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

VEARDLMSRLLCG-VDQRLGTK-GTHEIKSHSWF
.||.||...||     .|||.. | .|.|.|  |
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase NDR1_a-2.AA AktR 124-428 36 4.5e-106 358.69 In-house 1-268 (268) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-268/268
Sequence Identity: 36% (116 aa)

FELLTIIGRGAFGEVRLCREK-STGYVYAMKKLKKSEMLRRGQVEHVKAERNLLA-EVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTE
|... ..|.||||.| |...|  .. .|||| .||... .| | .|.  ||| .. ... . ||||. .||..|.|..|||| |||.. . | .| ...|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

NEAKFYIAEAVLAIESIHKH-KYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDANRRTSSPAPRRTQQEQLQHWQRN
..|.||.|. .||.|  |.| . | ||.||.|.|||..||.|..|||| |                                           ||  .. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------------------LQ-FMMH

RRMLAYSTVGTPDYIAPEVLLK-KGYGMECDWWSLGAILYEMLVGFPPFYS--DEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMS-RLLCGVDQ-RLG
.. .||| .||| |.|||...| ||..  .|||..|. .|||..| ||||.  .. ||   || . .  .|||. ...| ...||   .|||   . |||
YDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMF--QKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLG

--TKGTHEIKSHSWF
  ..|. ||||| ||
YYCNGWEEIKSHPWF
Kinase NDR1_a-2.AA DMPK 124-269 53 5.3e-106 262.86 In-house 1-147 (270) Show / Hide 
Range on Protein: 124-269
Range on HMM: 1-147/270
Sequence Identity: 53% (78 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKD-TLTEN
|| |..||||.|||| . |.|.|. |||||...| ||| | ..  .. ||. ..  .|  |..|.. |||..|||..||| ||||. ||. | .  . |.
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

EAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC
 |.||.|| |||| |||.  |.|||||||| |||..||.|| ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC
Kinase NDR1_a-2.AA S_TKc 124-428 32 5.5e-103 349.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-231/231
Sequence Identity: 32% (103 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPG--GDMMTLLMRKDT---
.|.| .||.||||.|..||.|.|| ..|.|..|          ||.. |...| . .  .||||| .||| ..||..|||..|  ||..... .. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDANRRTSSPAPRRTQQEQLQ
   ..| .|.||... ..|.| .|.|. ||||.||.|.|||.  |.|..||||.. |                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

HWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGM-ECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLC-GVDQR
          .. .|||.|.|||||   |||  .|||||.| ||||||.| |||.  ... . .||.              | ||.|.....|.   ..|
----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKR

LGTKGTHE----IKSHSWF
..     .    ||.| ||
PTA-EALQDEWDIKCHPWF
Kinase NDR1_a-2.AA RSK 124-428 33 9.1e-101 341.08 In-house 1-278 (278) Show / Hide 
Range on Protein: 124-428
Range on HMM: 1-278/278
Sequence Identity: 33% (108 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQ-VEHVKAERNLLAEVD-SNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDT---
 ..|. .| |..  .| |. . || .|||| |||... .|   ..|...||| |...  .  ||.|. .||....|||||||..||.. | | .. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDK---NGHLKLSDFGLCKPLDCSNFPMLRENDLSTDKNQRDGLDANRRTSSPAPRRTQQEQLQ
..|.||.||.|| |||.| .|... ||||.||.| |.|    .||.||.|||.|| .                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

HWQRNR-RMLAYSTVGTPDYIAPEVLL----KKGYGMECDWWSLGAILYEMLVGFPPFYS---DEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLL
   |..   .... ..| .|.|||.|     ..|..  |||||||...||||.|.|||..   . .  . ..| . .  |..|  ..|| ||.|| ...|
---RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKML

C-GVDQRLG--TKGTHEIKSHSWF
.    .|||   ... |||.|.||
HRDPHKRLGCGPQDAEEIKQHPWF
Kinase NDR1_a-2.AA Akt 124-270 46 9.8e-74 235.06 In-house 1-149 (264) Show / Hide 
Range on Protein: 124-270
Range on HMM: 1-149/264
Sequence Identity: 46% (70 aa)

FELLTIIGRGAFGEVRLCREKSTGYVY-AMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTEN
|..| ..|.|.|| | |...|.|. .| ||| |||.  . ..||||.|.|||.|  .....||.|. |||. ..||..|.| .||.  ..| || . .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EAKFYIAEAVLAIESIHKHKYIHRD-IKPDNLLLDKNGHLKLSDFGLCK
.|.||.|| .||||  |..  | ||  || |.|.||.||..| ||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK
Kinase NDR1_a-2.AA GEK 124-269 54 3.9e-65 217.49 In-house 1-147 (269) Show / Hide 
Range on Protein: 124-269
Range on HMM: 1-147/269
Sequence Identity: 54% (80 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMR-KDTLTEN
||.| .|||||||||   . |.|. ||||| |.| |||.|. .   . ||  | . |. .| .|   |||..||||.|.|  |||..||| . .| | |.
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

EAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC
 |.||||| |.||.|.|. .|.||||||||.|||.|||..| ||| |
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSC
Kinase NDR1_a-2.AA ROCK 124-269 52 4.2e-62 210.25 In-house 1-145 (263) Show / Hide 
Range on Protein: 124-269
Range on HMM: 1-145/263
Sequence Identity: 52% (77 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGGDMMTLLMRKDTLTENE
|... .|||||||||.| |.||.  ||||| | | ||..|        ||...|   |..||.|.. |||| |||..|.|.||||..  || .  . |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVN-LMSNYDVPEKW

AKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLC
|.|| .| |||...||   .||||.||||.|||| ||||| ||| |
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTC
Kinase NDR1_a-2.AA DMPK 329-428 49 4.6e-62 151.74 In-house 162-270 (270) Show / Hide 
Range on Protein: 329-428
Range on HMM: 162-270/270
Sequence Identity: 49% (54 aa)

VGTPDYIAPEVL--LKKG----YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNW-RTHLKFPDEAK--LSVEARDLMSRLLCGVDQRLGTKGT
|||||||.||||  .  .    || ||||||.| ..||||.|  ||| |    |  ||.|  ..||.|||. |  .|.||.||  .|||  ..|||  | 
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

HEIKSHSWF
 ..| | .|
EDFKCHPFF
Kinase NDR1_a-2.AA Pkinase 124-270 34 7.6e-53 186.67 Pfam 1-160 (293) Show / Hide 
Range on Protein: 124-270
Range on HMM: 1-160/293
Sequence Identity: 34% (55 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVK-AERNLLAEVDSNYIVKLYCSFQDDEYLYLIMEYLPGG----DMMTLLM--RK
.... .||.|.||.|..|..|.|| ..|.|..||..     ...|.. .|  ....... .||.||..|.|. ..|..|||..||    | .....  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DTL--TENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHL----KLSDFGLCK
 ..  .|.|.|||. . . ..| .|... ||||.||.|.|.|.|||.    |..||||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase NDR1_a-2.AA ROCK 329-428 50 1.2e-37 125.56 In-house 160-263 (263) Show / Hide 
Range on Protein: 329-428
Range on HMM: 160-263/263
Sequence Identity: 50% (53 aa)

VGTPDYIAPEVLLKKG----YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLCGVDQRLGTKGTHEIKS
|||||||.||||  .|    || |||||| |  .||||||  ||| |  . |  ||.. .. |||||....| .|.||. . |   .|||| .|  .|| 
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ

HSWF
| .|
HKFF
Kinase NDR1_a-2.AA Akt 325-428 41 8.1e-37 115.17 In-house 159-264 (264) Show / Hide 
Range on Protein: 325-428
Range on HMM: 159-264/264
Sequence Identity: 41% (45 aa)

AYSTVGTPDYIAPEVLLKKGYGMECDWWS-LGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAKLSVEARDLMSRLLCGV-DQRLG--TKGTH
...  ||| |.|||.|...|... .|||. ||...|||. |.||||..       || |    .||||  ..| |..|| |.||    ..|||   ....
TKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKN--QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQ

EIKSHSWF
|||.| ||
EIKRHPWF
Kinase NDR1_a-2.AA GEK 329-428 46 1.6e-36 119.86 In-house 162-269 (269) Show / Hide 
Range on Protein: 329-428
Range on HMM: 162-269/269
Sequence Identity: 46% (50 aa)

VGTPDYIAPEVL--LKKG---YGMECDWWSLGAILYEMLVGFPPFYSDEPMFTCRKIVNWRTHLKFPDEAK---LSVEARDLMSRLLCGVDQRLGTKGTH
|||||||.||.|  .  |   || |||||||| ..|||| |  |||..  . |  ||.|.. |..||.. .   .| ||.||. .|.|  ..|||  | .
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIKSHSWF
. | | .|
DFKKHPFF
Kinase NDR1_a-2.AA Pkinase 329-428 30 1.5e-23 84.37 Pfam 172-293 (293) Show / Hide 
Range on Protein: 329-428
Range on HMM: 172-293/293
Sequence Identity: 30% (38 aa)

VGTPDYIAPEVLL-KKGYGMECDWWSLGAILYEMLVGFPPFYSD------EPMFTCRKIVNWRTHLKFPDEAKLS-----------------VEARDLMS
.|||.|.||||..  ..|| ..|.||.| |||||| | |||...      ..|.  ..|   ..|  .| .   |                  |..|...
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

RLLC-GVDQRLGTKGTHEIKSHSWF
..||    .|..    ..|. | ||
WCLCKDPKKRPT---AEQILQHPWF
Kinase NDR1_a-2.AA Pkinase_Tyr 124-270 28 2.3e-13 45.86 Pfam 1-159 (270) Show / Hide 
Range on Protein: 124-270
Range on HMM: 1-159/270
Sequence Identity: 28% (45 aa)

FELLTIIGRGAFGEVRLCREK----STGYVYAMKKLKKSEMLR-RGQVEHVKAERNLLAEV-DSNYIVKLYCSFQ-DDEY--LYLIMEYLPGGDMMTLLM
 ...  .|.||||||.... |    .|..  | |.|| . | .     |   .| ... .  .   ||.||     ..|   .|..||| |.||. . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----KDTLTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCK
.    |. ||  .   . ..   . |  . ...||||.   | |...|.. | .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase NDR1_a-2.AA TyrKc 124-358 19 3.5e-12 -25.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 124-358
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

FELLTIIGRGAFGEVRLCREKSTGYVYAMKKLKKSEMLRRGQVEHVKAERNLLAEV--DSNYIVKLYCSFQDD-------EYLYLIMEYLPGGDMMTLL-
 .|. ..|.||||||.... |   .  | |.||..       .|    | ... ..  .   ||.||    ..       | |...||| |.||    | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

MRKDTLTENEAKFYIAEAVLAIESIHKHKYIHRDIKPDNLLLDKNGHLKLSDFGLCKPLDCS-NFPMLRENDLSTDKNQRDGLD-------------ANR
 ....|.  .   .   .    | .|....||||.   | |...|.. | |||||.. ..   .     |..   .| ...| .               .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---ESKDYYRKKEHKGGKTMLPIRWMAPECINYG

--------------------RTSSPAPR-----RTQQEQLQHWQRNRRMLAYST------VGTPDYIAPEVLLK---KGYGMECDWWSLGAIL
                    .  .| |       . || ... .. .||           |. || .   . ..       . .  . .  ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase NDR1_a-2.AA Pkinase_C 446-495 26 1.5e-11 43.93 Pfam 1-46 (46) Show / Hide 
Range on Protein: 446-495
Range on HMM: 1-46/46
Sequence Identity: 26% (13 aa)

EVNNELDTQNFEKFEEAIGQTQSSSKAGPWRKMLPSKDVNFVGYTYKNFE
.|....||.||.....    . ..    .|| | .... .|.|.||.|..
QVKSPTDTSNFDPEFTDEPPMDTP---PDWR-MSSGDQEPFRGFTYVNPD
Kinase NDR1_a-2.AA S_TK_X 429-493 24 4.2e-09 37.49 SMART 1-79 (79) Show / Hide 
Range on Protein: 429-493
Range on HMM: 1-79/79
Sequence Identity: 24% (22 aa)

KGVEWDKLY----EMEAAFKPEVN----NELDTQNFE-KFEEAIGQTQSSSKAGPWRKMLPSK------DVN----------FVGYTYKN
.|. |||||    |.|. |||...    .. || ||. .|.|.               . ...      . |          | |.||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-----------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF