Gene RSK-p1-S1-1 (S.moellendorffii)

RSK-p1-S1-1

Species: S.moellendorffii
Alias: RSK-p1-S1-1
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p1

Sequence

Name Sequence Type Origin Length Description Download
RSK-p1-S1-1.AA Protein None 176 None Fasta, JSON
RSK-p1-S1-1.NA RNA None 531 None Fasta, JSON
RSK-p1-S1-1.kin_dom Protein Kinase Domain None 123 None Fasta, JSON

Protein domain

Protein domains of RSK-p1-S1-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p1-S1-1.AA AGC 1-123 32 5.2e-87 224.25 In-house 192-395 (395) Show / Hide 
Range on Protein: 1-123
Range on HMM: 192-395/395
Sequence Identity: 32% (68 aa)

GHVKLTDFGLAKKAILDN--------------------------------------------------KSASTFCG--TPEYIAPEILCNSGHGRAADWW
||.|||||||.|. . |.                                                  . ..||||  ||||.|||||    .|.|.|||
GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWW

S--LGTLLYEMLCGLPPFYHKNVN----------IMYDRIL------NAKLTFP----------AFLTPVARDLLSKLLVRNPETRLGAGQRD-----YE
|  || |.||||.|.||||..|..           |...|.      | |..||           ...| |.||..|||...|| |||.|..|     .|
SFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAE

EIIEHQFF
|| .| .|
EIKNHPWF
Kinase RSK-p1-S1-1.AA SGK 1-123 52 2.5e-74 228.82 In-house 162-283 (283) Show / Hide 
Range on Protein: 1-123
Range on HMM: 162-283/283
Sequence Identity: 52% (64 aa)

GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLV
||..||||||.|  | .|.  .|||||||| |||.|   .|.|. |||.||..||||. ||||||..|...||| |.| .| .| . .. |.||.  || 
GHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQ

RNPETRLGAGQRDYEEIIEHQFF
..|. |||.  || .|| .|.||
KDPKKRLGT-KRDFMEIKNHPFF
Kinase RSK-p1-S1-1.AA Akt 1-123 48 2.8e-74 236.82 In-house 138-264 (264) Show / Hide 
Range on Protein: 1-123
Range on HMM: 138-264/264
Sequence Identity: 48% (62 aa)

GHVKLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWS-LGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFP--AFLTPVARDLLS
||..||||||.|.  | |.  . ||||||||.||||| . ||..|.|||. || ..|||.||.||||....  |.. |.|... ||   .. | ..||.|
GHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLIS

KLLVRNPETRLGAGQRDYEEIIEHQFF
.|| ..|. |||.|  | .|| .| .|
GLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase RSK-p1-S1-1.AA RSK 1-123 47 1.1e-58 201.33 In-house 144-278 (278) Show / Hide 
Range on Protein: 1-123
Range on HMM: 144-278/278
Sequence Identity: 47% (64 aa)

GHVKLTDFGLAKKAILD-NKSASTFCGTPEYIAPEILC----NSGHGRAADWWSLGTLLYEMLCGLPPFYH---KNVNIMYDRILNAK--LTFP--AFLT
||.||||||..|.. .| |. . |||.| ||.|||.|     ..||..|.|||||| |.|||| | |||..   .| .   .||...|  ||.|  ..|.
GHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLS

PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF
. |.||..|.| |.|. |||.| .| ||| .|..|
QEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase RSK-p1-S1-1.AA p70 1-123 50 2.2e-55 190.34 In-house 165-299 (299) Show / Hide 
Range on Protein: 1-123
Range on HMM: 165-299/299
Sequence Identity: 50% (68 aa)

GHVKLTDFGLAKKAILDNKS----------ASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAK--LTFPAFLT
|||.|||||| |. | | .             |||||.|| |||||  .||..| |||||| |.| || | |||   |     | || .|  |. |. ||
GHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLT

PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF
. .|||. ||| |.| .|.|||  | ..| ||.||
HEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase RSK-p1-S1-1.AA AktR 1-123 43 2.3e-55 190.26 In-house 139-268 (268) Show / Hide 
Range on Protein: 1-123
Range on HMM: 139-268/268
Sequence Identity: 43% (57 aa)

GHVKLTDFGLAK--KAILDNKSASTFCGTPEYIAPEILCN-SGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAK---LTFPAFLTPVARDL
||||.|||||.|  . . ..  | .|||||||.|||.. .  ||....|||..|...|||. |.||||||| |.|...|..      ..|. ... ..||
GHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDL

LS-KLLVRNPETRLGAGQRDYEEIIEHQFF
.  ||| .||. ||| .  . ||| .| .|
IQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase RSK-p1-S1-1.AA PKC 1-123 38 2.8e-55 177.55 In-house 137-262 (262) Show / Hide 
Range on Protein: 1-123
Range on HMM: 137-262/262
Sequence Identity: 38% (48 aa)

GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLV
||.|..|||..|  ... . .|||||||.|||||||     | . |||..| |.|||..| .||  ..   . . |.. .  .|  |.  | ....... 
GHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMT

RNPETRLGAGQRD---YEEIIEHQFF
.|||.|||.....    ..| ||.||
KNPEKRLGCHPQQEEGEQDIREHPFF
Kinase RSK-p1-S1-1.AA RSK 1-123 42 1.8e-54 187.26 In-house 142-271 (271) Show / Hide 
Range on Protein: 1-123
Range on HMM: 142-271/271
Sequence Identity: 42% (55 aa)

GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTF-------PAFLTPVARD
||.|..|||.||... .|. . |||.| .|.|||.|   ||..|.||||.|.|.|||| | .||..|. . . . |...||         ..|... | |
GHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKD

LLSKLLVRNPETRLGAGQRDYEEIIEHQFF
||...| |.|. |||||  . |.| .| .|
LLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase RSK-p1-S1-1.AA PKA 1-123 44 9.4e-53 181.58 In-house 138-263 (263) Show / Hide 
Range on Protein: 1-123
Range on HMM: 138-263/263
Sequence Identity: 44% (57 aa)

GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNS-GHGRAADWWSLGTLLYEMLCGLPPFYHK--NVNIMYDRILNAKLTFPAFLTPVA---RDL
||.|.|||| |||  .|.   .| ||||||.||||. .. |||.. |||.|| | |||| | |||| .  ... .|..|.|.|. || .... |   .||
GHIKITDFGFAKK--VDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDL

LSKLLVRNPETRLGAGQRDYEEIIEHQFF
..|||..... |.|  . . . | .| .|
IKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase RSK-p1-S1-1.AA RSK-Unclassified 1-123 39 9.2e-50 154.21 In-house 138-283 (283) Show / Hide 
Range on Protein: 1-123
Range on HMM: 138-283/283
Sequence Identity: 39% (58 aa)

GHVKLTDFGLAKKA--------------------ILDNKS-ASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNA
|||.||||.| ..|                    |.|  . .  |||| ||.|||..   ||..| ||| || ..|||| |.||.|  | | ..  |. .
GHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKN

KLTFP--AFLTPVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF
.. ||   ..   .|||. ||| |||  |||... | ..|  |.||
HVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase RSK-p1-S1-1.AA Pkinase 1-123 30 2.7e-41 147.09 Pfam 145-293 (293) Show / Hide 
Range on Protein: 1-123
Range on HMM: 145-293/293
Sequence Identity: 30% (48 aa)

GHV----KLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILC-NSGHGRAADWWSLGTLLYEMLCGLPPFYHK------NVNIMYDRILNAKLTFPAFLT
||.    |..||||||.. .  |  ..||||||.|.|||..  ....|...|.||.| .||||||| |||...      . . |..||. ..| |. . .
GHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWW

---------------------PVARDLLSKLLVRNPETRLGAGQRDYEEIIEHQFF
                     . ..|.....| ..|. |..      |.| .| .|
CSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase RSK-p1-S1-1.AA S_TKc 1-123 19 4.3e-10 -28.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-123
Range on HMM: 1-231/231
Sequence Identity: 19% (49 aa)

G---------------------------------------------------------------------------------------------------
                                                                                                    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

-----------------------------HVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGR-AADWWSLGTLLYEMLCGLPPFYHKNVNI
                             |.|..|||||..        .||||||.|.|||.|   |.|. ..||||.| .||||||| |||.  ... 
YQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQM

MYDRILNAKLTFPAFLTPVARDLLSKLLVRNPETRLGAGQRDY--EEIIEHQFF
|...|.          .| |.|...|.|...|| |..| .     ..|  |..|
MFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RSK-p1-S1-1.AA S_TK_X 124-176 20 2.7e-07 31.46 SMART 1-79 (79) Show / Hide 
Range on Protein: 124-176
Range on HMM: 1-79/79
Sequence Identity: 20% (17 aa)

ASVNWTSMLQ--KKIRPPFVPQVK----AADDVGNFDVVFTCEQITTTVWYADQ---------------------FIG---ER
....|   ..  |.| |||.|..|     . |..|||  || |...    . ..                     |.|    .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase RSK-p1-S1-1.AA Pkinase_C 143-166 45 0.000329 18.15 Pfam 1-24 (46) Show / Hide 
Range on Protein: 143-166
Range on HMM: 1-24/46
Sequence Identity: 45% (11 aa)

QVKAADDVGNFDVVFTCEQITTTV
||| ..|. |||. ||.|  . |.
QVKSPTDTSNFDPEFTDEPPMDTP