RSK-p1-S1-2

Species: S.moellendorffii
Alias: RSK-p1-S1-2
External Links:
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSK-p1

Sequence

Name Sequence Type Origin Length Description Download
RSK-p1-S1-2.AA Protein None 317 None Fasta, JSON
RSK-p1-S1-2.NA RNA None 954 None Fasta, JSON
RSK-p1-S1-2.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of RSK-p1-S1-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RSK-p1-S1-2.AA AGC 7-264 36 2.2e-190 497.75 In-house 1-395 (395) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-395/395
Sequence Identity: 36% (146 aa)

FKFLKVLGKGAFGKVYLVKKH------TTDEILAMKVLDKKD---LVDGKALEHTRTE------------RHILEAVQ----------HPFIVS-LRYAF
|.||||.|||.|||||||.|       .|... |||||.||.   . . . .||| ||            |.||| ..          |||||. | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEEK--FYMVMEFLS---------GG-ELFYHLKV--ASR-FKEDRSRFYASE-------ITLAIGHLHG-LGIVYRD-LKAENVLLDAEGHVKLTDFG
|....   |.|||...         || |||.||.    .. | |.|.||||.|       |.||. .||  .||..|| || ||.|||..||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKKAILDN--------------------------------------------------KSASTFCG--TPEYIAPEILCNSGHGRAADWWS--LGTLLY
|.|. . |.                                                  . ..||||  ||||.|||||    .|.|.||||  || |.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLCGLPPFYHKNVN----------IMYDRIL------NAKLTFP----------AFLTPVARDLLSKLLVRNPEKRLGAGQRD-----YEEIIEHQFF
|||.|.||||..|..           |...|.      | |..||           ...| |.||..|||...||||||.|..|     .||| .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase RSK-p1-S1-2.AA Akt 7-264 54 2.7e-164 529.19 In-house 1-264 (264) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-264/264
Sequence Identity: 54% (143 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEIL-AMKVLDKKDLVDGKALEHTRTERHILEAVQHPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLKVASRFKED
| ||||||||.||||.||||  |...  ||||| |. ... . .||| ||| ||. ..|||||.| |.|||..| |.||.. .||||||||. . ||.||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RSRFYASEITLAIGHLHGLGIVYRD-LKAENVLLDAEGHVKLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWS-LGTLLYEMLCGL
| |||..|| |||.|||  .|.||| || ||.|.|..||..||||||.|.  | |.  . ||||||||.||||| . ||..|.|||. || ..|||.||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYHKNVNIMYDRILNAKLTFP--AFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
||||....  |.. |.|... ||   .. | ..||.|.|| ..|.||||.|  | .|| .| .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase RSK-p1-S1-2.AA SGK 7-264 48 1.8e-161 502.77 In-house 1-283 (283) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-283/283
Sequence Identity: 48% (139 aa)

FKFLKVLGKGAFGKVYLVKKHTT------------------DEILAMKVLDKKDLV-------DGKALEHTRTER-HILEAVQHPFIVSLRYAFQTEEKF
|.||||.||| |||||.||.  .                  | . ||||| |.  .         |   |. .||  ||  . |||||.|.|||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMVMEFLSGGELFYHLKVASRFKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNS
|.||... |||.||||. . .|.|||.||||.|| .|...|| . |.||||| ||.|||..||..||||||.|  | .|.  .|||||||| |||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
.|.|. |||.||..||||. ||||||..|...||| |.| .| .| . .. |.||.  || ..|.||||.  || .|| .|.||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF

Kinase RSK-p1-S1-2.AA RSK 10-264 50 3.9e-135 455.24 In-house 1-278 (278) Show / Hide
Range on Protein: 10-264
Range on HMM: 1-278/278
Sequence Identity: 50% (141 aa)

LKVLGKGAFGKVYLVKKH---TTDEILAMKVLDKKDLVDG-KALEHTRTERHILEAVQ-HPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLKVASR---
|||||.|..|||.|..|     |. | |||||.|. .|   |...||.||| |||..| |||||.| ||||||.|.|..||...|||||.||.   .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDA---EGHVKLTDFGLAKKAILD-NKSASTFCGTPEYIAPEILC----NSGHGRAADWWSLGT
| ||. .||..||.||. ||| .||..|||| ||.|.|    |||.||||||..|.. .| |. . |||.| ||.|||.|     ..||..|.|||||| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEMLCGLPPFYH---KNVNIMYDRILNAK--LTFP--AFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
|.|||| | |||..   .| .   .||...|  ||.|  ..|.. |.||..|.| |.|.||||.| .| ||| .|..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase RSK-p1-S1-2.AA p70 7-264 47 2.3e-133 449.36 In-house 1-299 (299) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-299/299
Sequence Identity: 47% (143 aa)

FKFLKVLGKGAFGKVYLVKKHT---TDEILAMKVLDKKDLV-DGKALEHTR-------------------------TERHILEAVQHPFIVSLRYAFQTE
|. |||||||..|||..|.| |   |  | ||||| |   |   |...|||                          || |||.|.||||. | |||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

EKFYMVMEFLSGGELFYHLKVASRFKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILDNKS----------ASTFCG
.| | . |.|.|||||.||.  . . ||  .||.|||..|..|||..||.||||| ||..|.. |||.|||||| |. | | .             ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAK--LTFPAFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
|.|| |||||  .||..| |||||| |.| || | |||   |     | || .|  |. |. ||. .|||. ||| |.| .|.|||  | ..| ||.||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF

Kinase RSK-p1-S1-2.AA AktR 7-264 47 2.4e-132 445.97 In-house 1-268 (268) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-268/268
Sequence Identity: 47% (128 aa)

FKFLKVLGKGAFGKVYLVKKH-TTDEILAMKVLDKKDLVDGKALEHTRTERHILE-AVQHPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLKVASRFKE
|...|.||||||||||||.|  ..... |||...||.... .. .||.||| |.|  ..||||| | |.|||.|| . .||.  |||||.|||   .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DRSRFYASEITLAIGHLHGL-GIVYRDLKAENVLLDAEGHVKLTDFGLAK--KAILDNKSASTFCGTPEYIAPEILCN-SGHGRAADWWSLGTLLYEMLC
...|||...| ||. .||    |.||||| || ||| .||||.|||||.|  . . ..  | .|||||||.|||.. .  ||....|||..|...|||. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYHKNVNIMYDRILNAK---LTFPAFLTPVARDLLS-KLLVRNPEKRLGAGQRDYEEIIEHQFF
|.||||||| |.|...|..      ..|. ... ..||.  ||| .||.|||| .  . ||| .| .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase RSK-p1-S1-2.AA PKA 7-264 43 2.4e-121 409.44 In-house 1-263 (263) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-263/263
Sequence Identity: 43% (115 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTRTERHILEAVQHPFIV-SLRYAFQTEEKFYMVMEFLSGGELFYHLKVASRFKED
|.....||.| ||.|.|... .. .. |||.|.| . |. |  ||. .|..|| ...||||| .. . ||.. . |||||. .|||.|..|    || ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RSRFYAS-EITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNS-GHGRAADWWSLGTLLYEMLCGLP
 ..|||  .|.||.  || . |.||||| || |.| .||.|.|||| |||  .|.   .| ||||||.||||. .. |||.. |||.|| | |||| | |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK--VDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYHK--NVNIMYDRILNAKLTFPAFLTPVA---RDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
||| .  ... .|..|.|.|. || .... |   .||..|||.....||.|  . . . | .| .|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase RSK-p1-S1-2.AA PKC 7-264 44 6.6e-120 390.4 In-house 1-262 (262) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-262/262
Sequence Identity: 44% (117 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTRTERHILE-AVQHPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLKVASRFKED
|.|||||||| |||| |...  |||. |.||| |   ..    | |.||...|. | .||| ..|   |||... . |||.. || | .|   . |||| 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEMLCGLPPF
. |||| ||..|   ||  ||.||||| .|||||.|||.|..|||..|  ... . .|||||||.|||||||     | . |||..| |.|||..| .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLVRNPEKRLGAGQRD---YEEIIEHQFF
  ..   . . |.. .  .|  |.  | ....... .|||||||.....    ..| ||.||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase RSK-p1-S1-2.AA RSK 7-264 41 2.9e-118 399.19 In-house 1-271 (271) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-271/271
Sequence Identity: 41% (114 aa)

FKFLKVLGKGAFGKVYLVKKH---TTDEILAMKVLDKKDLVDGKALEHTRTERHILEAVQHPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLKVASRFK
. .....|.|.|.|||..||     |.   |||...|. ..       . .|| ||. ..||||| |.|.||.|.| ||.|.|. ||.|| .|     | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAE----GHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGRAADWWSLGTLLYEML
|.  .||..||.||  .|| .|||.||||.||.|.|.|    ||.|..|||.||... .|. . |||.| .|.|||.|   ||..|.||||.|.|.||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

CGLPPFYHKNVNIMYDRILNAKLTF-------PAFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
 | .||..|. . . . |...||         ..|... | |||...| |.|..|||||  . |.| .| .|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase RSK-p1-S1-2.AA RSK-Unclassified 7-264 42 2.3e-114 360.76 In-house 1-283 (283) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-283/283
Sequence Identity: 42% (119 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTRTERHILEAVQHPFIVSLRYAFQTEEKFYMVMEFLSGGELFYHLK--VASRFKE
|   . .|.| |||||||.|  |. | ||||| |. ..  .      ||. |.   .||||| | ..|||. . |..||.  ||..| ||      .| |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKA--------------------ILDNKS-ASTFCGTPEYIAPEILCNSGHG
|. ||||||.|.|  .|| ....||||| .|..|. ||||.||||.| ..|                    |.|  . .  |||| ||.|||..   ||.
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

RAADWWSLGTLLYEMLCGLPPFYHKNVNIMYDRILNAKLTFP--AFLTPVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
.| ||| || ..|||| |.||.|  | | ..  |. ... ||   ..   .|||. ||| ||| ||||... | ..|  |.||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF

Kinase RSK-p1-S1-2.AA S_TKc 7-264 39 5.3e-110 372.67 SMART 1-231 (231) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-231/231
Sequence Identity: 39% (107 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTRTERHILEAVQHPFIVSLRYAFQTEEKFYMVMEFLSG--GELFYHLKVASR---
...|...|||||||||..... |..| |.|...          ||.| |. ||.  .||.|| | ..||. ...|||||...|  |.|| ..|   |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILDNKSASTFCGTPEYIAPEILCNSGHGR-AADWWSLGTLLYE
   | | . |||. .| .|. ..| .||..|||| ||.|||   |.|..|||||..        .||||||.|.|||.|   |.|. ..||||.| .|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLCGLPPFYHKNVNIMYDRILNAKLTFPAFLTPVARDLLSKLLVRNPEKRLGAGQRDY--EEIIEHQFF
|||| |||.  ... |...|.          .| |.|...|.|...||||..| .     ..|  |..|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase RSK-p1-S1-2.AA Pkinase 7-264 32 1.4e-93 321.99 Pfam 1-293 (293) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTR-TERHILEAVQHPFIVSLRYAFQTEEKFYMVMEFLSGG----ELFYHLK--VA
.......|.|.||.||. ... | .| |.|...|..  ..|  .|.| .| .|.  ..||.|| |...|... . |||||.. ||    .|| ...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SRF--KEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHV----KLTDFGLAKKA-ILDNKSASTFCGTPEYIAPEILC-NSGHGRAADWWSL
 .|   |.  .||. .|  .. ..|  ||..|||| ||.|.| .||.    |..||||||.. .  |  ..||||||.|.|||..  ....|...|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GTLLYEMLCGLPPFYHK------NVNIMYDRILNAKLTFPAFLT---------------------PVARDLLSKLLVRNPEKRLGAGQRDYEEIIEHQFF
| .||||||| |||...      . . |..||. ..| |. . .                     . ..|.....| ..|.||..      |.| .| .|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF





Kinase RSK-p1-S1-2.AA TyrKc 7-258 20 3.4e-14 6.72 SMART 1-280 (280) Show / Hide
Range on Protein: 7-258
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FKFLKVLGKGAFGKVYLVKKHTTDEILAMKVLDKKDLVDGKALEHTRTERHILEAV--QHPFIVSLRYAFQTE-------EKFYMVMEFLSGGELFYHLK
 ...|.|| ||||.||. .     .  | |.| .        .|  . |  |.  .  .|| || |  .  ..       |  ..|||. ..| |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

VASR-FKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAKKAILD--------NKSASTFCGTPE-----YIAPEILCNSGHG
   . .. .    ..  |     .||  ... ||| | |.|......|| .||||...   |         .....  |.         ||| .  .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RAADWWSLGTLLYEML-CGLPPFYH-----KNVNIMYDRILNA-KLTFPAF--------LTPVARDLLSKLLVRNPEKRLGAGQRDYEEI
 . | || | ...|..  | .| .      ..   .. .. .   .  |.          ..   .. ..   ..||.|    .  .|..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase RSK-p1-S1-2.AA Pkinase_Tyr 7-153 28 5.6e-13 44.59 Pfam 1-159 (270) Show / Hide
Range on Protein: 7-153
Range on HMM: 1-159/270
Sequence Identity: 28% (46 aa)

FKFLKVLGKGAFGKVYLVKKH----TTDEILAMKVLDKKDLVDGKA--LEHTRTERHILEAV-QHPFIVSLRYAFQ-TEEK--FYMVMEFLSGGELFYHL
 .|.|.||.||||.||. . .     |.   | |.|  |.  . ..  .|    |  |.    .|| ||.|  .    .|    |.|||.  .| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KV----ASRFKEDRSRFYASEITLAIGHLHGLGIVYRDLKAENVLLDAEGHVKLTDFGLAK
.       ...  .   .. .|  .  .|.  ... ||| | |.|.. ...|| .|||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase RSK-p1-S1-2.AA S_TK_X 265-316 20 6.9e-09 36.77 SMART 1-79 (79) Show / Hide
Range on Protein: 265-316
Range on HMM: 1-79/79
Sequence Identity: 20% (16 aa)

ASVNWTSMLQ--KKIRPPFVPQVK----GGDDVGNFDVVFTCEQITTTVW---------------------YADQFIRE
....|   ..  |.| |||.|..|    .  |..|||  || |... |.                      ... . . 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase RSK-p1-S1-2.AA Pkinase_C 284-307 45 0.0002 18.91 Pfam 1-24 (46) Show / Hide
Range on Protein: 284-307
Range on HMM: 1-24/46
Sequence Identity: 45% (11 aa)

QVKGGDDVGNFDVVFTCEQITTTV
|||. .|. |||. ||.|  . |.
QVKSPTDTSNFDPEFTDEPPMDTP