Gene HisK_b (S.moellendorffii)

HisK_b

Species: S.moellendorffii
Alias: HisK_b
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_b.AA Protein None 1077 None Fasta, JSON
HisK_b.NA RNA None 3234 None Fasta, JSON

Protein domain

Protein domains of HisK_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CHASE HisK_b.AA CHASE 211-382 25 6.7e-30 108.01 Pfam 20-203 (203) Show / Hide 
Range on Protein: 211-382
Range on HMM: 20-203/203
Sequence Identity: 25% (49 aa)

TSFERPLMSGVAYAHNVEHWQRRAFEEEMG------WSI--KEM--RSNAPRAQNLDEYAPTVLSQNTL---AHLASVDMMSGEEDRENILRSRASGKGA
.  . | . |...| .|.| || |||..|       ..|  .|.    .  .| ..|.|.| .. . .     .    ||.| .. || ..|.|..|. .
LLRRYPGIQGIGWAPRVPHEQRAAFEQQMRAEGFPDFNIQNWEPDADGQW-PAPHRDPYFPITYIYPFDWGNERALGFDMYSEPVRREAMERARDTGQPV

LTSPFRLLESDHLGVVLTFTVYKTDLPDDATPAQ--RI---QATAGYVGGAFDFESLVENLLRQLSESQTIIVNVNDVTNKSNPLVMYGP
|| |..|.  .. |... . || .. . ..|..|  |    ||  |.| . |. ..|.|.|| ..   ..| ... |.|. . . ..|| 
LTGPVTLVQEGQRGFLMYMPVY-RGGMPPTTVEQPPRRPGNQALWGWVYAVFRMDDLMEGLL-NQ---DGIAIRIYDGTDGADGELFYGS
HisKA HisK_b.AA HisKA 468-533 33 5e-27 97.02 SMART 1-89 (89) Show / Hide 
Range on Protein: 468-533
Range on HMM: 1-89/89
Sequence Identity: 33% (30 aa)

AKSQFLATVSHEIRTPMNGVLGMLQMLMD----------TELDSTQ-------------RDYAHTALESGKQLIKLINEVLDQAKIESG
||.||||..|||.|||.....|....| |          |.||. |             |.| .|........ .|||..|| ..||.|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA HisK_b.AA HisKA 468-533 43 3e-26 94.44 Pfam 1-69 (69) Show / Hide 
Range on Protein: 468-533
Range on HMM: 1-69/69
Sequence Identity: 43% (30 aa)

AKSQFLATVSHEIRTPMNGVLGMLQMLMD-TELDSTQ--RDYAHTALESGKQLIKLINEVLDQAKIESG
||.||||..|||.|||.....|....| | |.||. |  |.| .|........ .|||..|| ..||.|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HATPase_c HisK_b.AA HATPase_c 580-764 28 2.7e-38 135.53 Pfam 1-120 (120) Show / Hide 
Range on Protein: 580-764
Range on HMM: 1-120/120
Sequence Identity: 28% (55 aa)

GDPVRLHQIVTNLVGNSIKFTDR-GHIFVSVHLEEDVKAAMSAQCEACSKQVTETQDHSDKLNTVDAAGSCSTLSGLEAADRRNNWETFKLILKQEKSRL
|||.||||.|.|||.|.||.|   ||| |.|| ..                                                                 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------------------------------------------------------

TTHKQPVDTVKLVFSVEDTGVGIPV------HAQERVFSPFMQADS-STSRNYGG--TGIGLSISKCLVELMKGEIGFVSSLGVGTTFWFTVNFK
           ....|||.|.|||.      . ..|.| || ..|. |. |.|||  ||.||.|.. .||.. |.| . |. | ||||.||. ..
---------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE
HATPase_c HisK_b.AA HATPase_c 580-765 23 2.1e-37 131.47 SMART 1-130 (130) Show / Hide 
Range on Protein: 580-765
Range on HMM: 1-130/130
Sequence Identity: 23% (51 aa)

GDPVRLHQIVTNLVGNSIKFTDR--------------GHIFVSVHLEEDVKAAMSAQCEACSKQVTETQDHSDKLNTVDAAGSCSTLSGLEAADRRNNWE
|||.||.|...||..|.||.|.               |.| |.||                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

TFKLILKQEKSRLTTHKQPVDTVKLVFSVEDTGVGIPV------HAQERVFSPFMQADS--------STSRNYGG--TGIGLSISKCLVELMKGEIGFVS
                         ...|||.|.|||       . ..|.| || ..|.        |.||.|||  ||.||||.| .||.. |.| .  
-------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE-

SLGVGTTFWFTVNFKV
     |||.||.  ..
-----TTFTFTLPLER
Kinase HisK_b.AA HisK 580-764 17 1.7e-25 88.56 In-house 1-164 (164) Show / Hide 
Range on Protein: 580-764
Range on HMM: 1-164/164
Sequence Identity: 17% (40 aa)

GDPVRLHQIVTNLVGNSIKFTDRG------HIFVSVHLEEDVKAAMSAQCEACSKQVTETQDHSDKLNTVDAAGSCSTLSGLEAADRRNNWETFKLILKQ
 || |. ||. ||..|..|||. |      .| ..| . .. .  .                                        .  | .        
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN-I----------------------------------------KY-N-S--------

EKSRLTTHKQPVDTVKLV---------------FSVEDTGVGIPVHAQERVFSPFMQ----------ADSSTSR--NYGGTGIGLSISKCLVELMK----
           .  .|.                .||.|||.|.| . |.  | .| .           ..  .   |  | |.||.|.. |....     
-----------IFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHN

----GEIGFVSSLGVGTTFWFTVNFK
    ..| ..|  |.|.||.| .. .
QNGNRGIQVQSEVGKGSTFSFYIYNN
REC HisK_b.AA REC 799-911 19 0.000311 4.35 SMART 1-150 (150) Show / Hide 
Range on Protein: 799-911
Range on HMM: 1-150/150
Sequence Identity: 19% (31 aa)

LKALVVDGR----PVRSEVTR------YHLRRLGIQ--------VDVASDVS-------SALAHQRSK-------------NLDMILIDKDAWG------
.. |.||      ||  |. |      . |...|..        ||.| |          ||.  ...             . | |..|    |      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

SSTGLSYPSKIKEAGPTLAPKLVLL-AFDDDEHKAKA-AGFSDNVIKKPLRASHIANHL
   |.    .|.        . ..| |.||.|.. .| .   |  | || .. ..   .
GMDGIELCRRIR--------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg HisK_b.AA Response_reg 801-849 31 0.0175 11.46 Pfam 1-51 (115) Show / Hide 
Range on Protein: 801-849
Range on HMM: 1-51/115
Sequence Identity: 31% (16 aa)

ALVVDGRPVRSEVTRYHLR-RLGI-QVDVASDVSSALAHQRSKNLDMILID
 |.||  |.  |. |  |. . |.  |..|.|  .||.  . .  |.|..|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMD
REC HisK_b.AA REC 957-1073 25 7.9e-33 116.3 SMART 1-150 (150) Show / Hide 
Range on Protein: 957-1073
Range on HMM: 1-150/150
Sequence Identity: 25% (41 aa)

KWILVVDDN----KVNRRVAA------GALQKYGAR--------VECVESGR-------LAIEKLEPPH------------KFDACFMDIQMP-------
. ||.|||.     |.|.. .       .|.| | .        |... .|.        |.|.|.  .            ..| ..|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

EMDGFEATRRIRCFEKRGGSHVPILAMTADVIQATYDECRRCGMDDYVSKPFEEKQLYRAV
.|||.|..||||          ||...||    ..  .... |.|||..|||. ..|  ..
GMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg HisK_b.AA Response_reg 959-1074 33 3.1e-29 107.26 Pfam 1-115 (115) Show / Hide 
Range on Protein: 959-1074
Range on HMM: 1-115/115
Sequence Identity: 33% (40 aa)

ILVVDDNKVNRRVAAGALQ-KYGA-RVECVESGRLAIEKLEPPHKFDACFMDIQMPEMDGFEATRRIRCFEKRGGSHVPILAMTADVIQATYDECRRCGM
.|.|||. ..|.. . .|. |.|  .|. ...|. |.|.. . |..| ..|||.||.|||.|..||||  ..   ...||...||    ..  |. . |.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHHPDLIIMDINMPGMDGLELCRRIRRQHP--HPQTPIIMCTAHGDEDDAVEALQAGA

DDYVSKPFEEKQLYRAVA
.||..||| . .|. |..
NDYITKPFDPDELHAAIR