HisK_n

Species: S.moellendorffii
Alias: HisK_n
External Links:
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
HisK_n.AA Protein None 1118 None Fasta, JSON
HisK_n.NA RNA None 3357 None Fasta, JSON

Protein domain

Protein domains of HisK_n.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA HisK_n.AA HisKA 486-552 33 1.8e-22 81.93 SMART 1-89 (89) Show / Hide
Range on Protein: 486-552
Range on HMM: 1-89/89
Sequence Identity: 33% (30 aa)

YKSQFLANMSHELRTPMAAVIGLLDILLT---------DACLTVEQI-------------AIVSQIRHCSTALLRLLNNILDLSKVESG
 |.|||||||||||||..|..|....|..         .. |. ||.              ....|....  ..||.|..||||. |.|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

HisKA HisK_n.AA HisKA 486-552 42 4.2e-21 76.52 Pfam 1-69 (69) Show / Hide
Range on Protein: 486-552
Range on HMM: 1-69/69
Sequence Identity: 42% (29 aa)

YKSQFLANMSHELRTPMAAVIGLLDILLTDACLTVEQ--IAIVSQIRHCSTALLRLLNNILDLSKVESG
 |.|||||||||||||..|..|....|.... |. ||    ... |....  ..||.|..||.|. |.|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HATPase_c HisK_n.AA HATPase_c 597-725 30 3.8e-30 107.15 Pfam 1-120 (120) Show / Hide
Range on Protein: 597-725
Range on HMM: 1-120/120
Sequence Identity: 30% (43 aa)

GDLTRTVQIFANLIGNSIKFTSS-GYITIRGWAEPFVSRYEPLEASGGHIEKFLLWFEVDDSGCAGIDP------SKWETVFDSFVQADT-STSRTHGG-
|| .| .|.. ||..|.||.| . | ||.| ....                   ....| |.|. ||.|       . ...|. |...|  |. | .|| 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------DHVRITVEDNGP-GIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGG

-TGLGLCIVRSLVSKMGGEIKVVKKEEPGTLMRFYLMYD
 ||||| |.| .| ..||.| |  ... || ..|.|  .
LTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE

HATPase_c HisK_n.AA HATPase_c 597-726 26 2.5e-27 98.05 SMART 1-130 (130) Show / Hide
Range on Protein: 597-726
Range on HMM: 1-130/130
Sequence Identity: 26% (42 aa)

GDLTRTVQIFANLIGNSIKFTSS--------------GYITIRGWAEPFVSRYEPLEASGGHIEKFLLWFEVDDSGCAGIDP------SKWETVFDSFVQ
|| .|  |.. ||..|.||.| .              | ||.| .                       ...| |.|. ||.|       . ...|. |..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------------------RITVEDNGP-GIPPEMHKSIEDIPRIFEPFYR

ADT--------STSRTHGG--TGLGLCIVRSLVSKMGGEIKVVKKEEPGTLMRFYLMYDS
.|         |.|| .||  ||||| |....| ..||.|.|       | ..|.|    
TDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE------TTFTFTLPLER

Kinase HisK_n.AA HisK 597-725 22 3.6e-13 44.15 In-house 1-164 (164) Show / Hide
Range on Protein: 597-725
Range on HMM: 1-164/164
Sequence Identity: 22% (39 aa)

GDLTRTVQIFANLIGNSIKFT------SSGYITIR---------GWAEPFVSRYEPLEASGGHIEKF----------LLWFEVDDSGCAGIDPSKWETVF
 |  |  ||  |||.|..|||      ..|||.|                  .|.  ...  .|..           |... | |.|| |..... .  |
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI-------KYN--SIFIQKIQENMVQEQLQQKNLIQISVQDTGC-GMPEEQQKKIF

DSFVQADT-------STSRTHG-----GTGLGLCIVRSLVSKMG--------GEIKVVKKEEPGTLMRFYLMYD
. | . |.       ...  ..     | |||| | ..|. ..|        ..|.|. ..  |.   ||.  .
KMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

REC HisK_n.AA REC 981-1108 30 2.2e-36 128.1 SMART 1-150 (150) Show / Hide
Range on Protein: 981-1108
Range on HMM: 1-150/150
Sequence Identity: 30% (50 aa)

IHILLAEDT----PVIQKVAV------VLLKKLGAT--------VVAVADGQ-------AAVEAWKGSL--KDQAVVDEERKPFDLILMDCQMP------
..||...|     |||...         ||.|.| .        |... ||.       .|.|...     |..|  |  ..|.|||.||..||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-RMDGYGATREIRKAEEGSGSHVPIVALTAHAMSSDEERCLEVGMDAYLTKPIDCKLMATTI
 .|||. ..|.||          ||..||||.. .| .|.||.|.|.|.|||.| . .  .|
GGMDGIELCRRIR----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg HisK_n.AA Response_reg 983-1109 30 1e-27 101.81 Pfam 1-115 (115) Show / Hide
Range on Protein: 983-1109
Range on HMM: 1-115/115
Sequence Identity: 30% (39 aa)

ILLAEDTPVIQKVAVVLLK-KLGA-TVVAVADGQAAVEAWKGSLKDQAVVDEERKPFDLILMDCQMPRMDGYGATREIRKAEEGSGSHVPIVALTAHAMS
.|...| |..... . .|. | |   | ...||..|.| |            ... .|||.||..||.|||. ..|.||....   ...||...|||.. 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW------------QEHHPDLIIMDINMPGMDGLELCRRIRRQHP--HPQTPIIMCTAHGDE

SDEERCLEVGMDAYLTKPIDCKLMATTIL
.| ...|..|.. |.|||.|   . . | 
DDAVEALQAGANDYITKPFDPDELHAAIR