Gene CAMK1c-S3_b (S.moellendorffii)

CAMK1c-S3_b

Species: S.moellendorffii
Alias: CAMK1c-S3_b
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S3_b.AA Protein None 294 None Fasta, JSON
CAMK1c-S3_b.NA RNA None 885 None Fasta, JSON
CAMK1c-S3_b.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S3_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S3_b.AA S_TKc 25-277 28 1.5e-62 215.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKEIMLKLNGCHGTLEIYDMVEEELKGRWWGSLILELCSC---TLRDRLKMVGR------LA
|... ..|||. |.|...  .  |.. | |   .. .|| .|. |  ..     .||. ..   .. .  ...|.|.    .|.|..|  ||      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK--HHPNIVKLYDVFQD---DHLY--MVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

DGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDLHHLCGTPGYMSPDVLRAGEGGWPKYYTQ-AVDVWGLGLILYELLS
  .|.|..  ... |  .|..|..||| | ||.||..     ..|..|||.|. |...|||| ||.| ||          |.  ..|.| .| ||||.|.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQLTTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYEMLC

GRVAFPEYHSDYVELLLKSVDNVEFALDWSDVTSEAKDLIMGMLEVYPSRRLTVEQVLG-------HPWI
|.  ||    .. ... | .            ..||||.|...|.. |..|.|. ..|        |||.
GYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CAMK1c-S3_b.AA CAMK 30-277 19 9.4e-60 190.9 In-house 1-425 (425) Show / Hide 
Range on Protein: 30-277
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

ELGKGGQGTVHLVSFRMGG------------KLLAAKSFERSG-----------------------------------EREKEIMLKLNG------CHGT
.||.|. |.|.|.  .  .            .  |.|  ...                                    .|| ||| ||.|          
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LEIYDMVEE----------ELKGR-WWGS------LIL---ELCSCT-----LRDRLKMV---------------GRLADGEAAFVTESLAETLREMHNL
. .|.. |           |   .  . .      ...   |.||       | |...                 ||.   ||...   ... .. .|..
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GVVHRDMKLENVLLTHPA--QP------------YEVKLSDFGVATD------------------------------LHHLCGTPGYMS-PDVLRA-GEG
..|||| |.||.||..    ..            . .|..||| |.                               ..  ||||.||. | ||.  | .
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

GW-------PKYYTQAVDVWGLGLILYELLSGRVAFPEYHSD----------YVELLLKSVDNVEFALD---------------WSDVTSE--------A
 .        .||....|.| .| ||| .|.|.  | . . .            . |.. . . ..  .               |.|.. |        .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KDLIMGMLEVYPSRRLTVEQVLGHPWI
|||| .||.| |..|.|.||.| |||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase CAMK1c-S3_b.AA Pkinase 25-277 26 3.9e-47 167.7 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-293/293
Sequence Identity: 26% (82 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSGEREKE-----------IMLKLNGCHGTLEIYDMVEEELKGRWWGSLILELCSC-----TLRDRL
| .|  .|.|. |.| .   .  ||. | | .....|....           ||..|| ..  ...||..|.  |.. .  ...|.| .      | |..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-VRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYI

K--MVGRL--ADGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTHPAQP-YEVKLSDFGVA-------TDLHHLCGTPGYMSPDVLRAGEGGWPKYY
.  . |..   . |. |.   ... |  .|. |..|||.|.||.|. .  ..   ||..|||.|       . ....||||.||.| |.|       .||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIR-----GGQYY

TQAVDVWGLGLILYELLSGRVAFPEY----HSDYVELLLKSVDNVEFALDWSDVT--------------------SEAKDLIMGMLEVYPSRRLTVEQVL
...||.|..|.||||.|.||  ||.     . .    ... .   ..  ||.                       .|.||.| ..|.. |..|.| ||.|
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

GHPWI
 |||.
QHPWF
Kinase CAMK1c-S3_b.AA AGC 133-277 20 1.3e-45 114.73 In-house 169-395 (395) Show / Hide 
Range on Protein: 133-277
Range on HMM: 169-395/395
Sequence Identity: 20% (49 aa)

MHN-LGVVHRD-MKLENVLLTHPAQPYEVKLSDFGVATD---------------------------------------------------------LHHL
.|. .|..||| .|.||.||..      .||.||| ..                                                           . .
LHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTF

CG--TPGYMSPDVLRAGEGGWPKYYTQAVDVWG--LGLILYELLSGRVAFPEYHSD-------YVELLLKSVD------NVEFALDW---------SDVT
||  || ||.| .|          |..|.| |.  || ..||.|.|.  |     .         . . ...       | .  ...         . ..
CGPCTPEYMAPEIL----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFS

SEAKDLIMGMLEVYPSRRLT----------VEQVLGHPWI
.|||||| ..|.. |..||.          .|..  ||| 
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CAMK1c-S3_b.AA Ciliate-E2 95-277 21 2.1e-43 146.85 In-house 111-365 (365) Show / Hide 
Range on Protein: 95-277
Range on HMM: 111-365/365
Sequence Identity: 21% (60 aa)

LILELCSC-TLRDRLK------------MVGRLADGEAAFVTESLAE---------------TLREMHNLG-VVHRDMKLENVLLTHPAQPYEVKLSDFG
|..|.|.  .|.|..|              ... . |...... ...                |...|. . ..||| |.||.|.        .|..|||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFG

VATDLHHL--------------------------------------CGTPGYMSPDVLRAGE-----GGWPKYYTQAVDVWGLGLILYELLSGRVAFPEY
 .....                                        |||||||.| .|. ..     ..  |.|. ..|.| || ||||.|.|.  |   
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ--KGYDYKCDIWSLGVILYEMLFGKPPF---

HSDYVELLLKSVDNVEFALD---------------WSDVTSEAKDLIMG----MLEVYPSRRLT-VEQVLGHPWI
      .  .   ...|                  | ... |.||||      ||.. |. |.|  ||.| |||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CAMK1c-S3_b.AA CAMKL 95-277 28 2.6e-39 123.02 In-house 98-297 (297) Show / Hide 
Range on Protein: 95-277
Range on HMM: 98-297/297
Sequence Identity: 28% (59 aa)

LILELCSCT---LRDRLKMV----GRLADGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTHPA-QPYEVKLSDFGVA---TD--------LHHLCG
|..|.||     | |...      ||.  .|| .    . . .  .|..|.|||| |.||.||..   .   .|..||| .   ..        |.  ||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELLSGRVAFPEYH------SDYVELLLKSVDNVEFALDWSDVTSEAKDLIMGMLEVYPSRRLTVE
.| ||.| ..  .     .|. ..||.| .| ||| .. |.. | . .      ... .|..|     ..   |..|  ...||| .||.| |..| |..
SPPYMAPEIFQGN---NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIH

QVLGHPWI
|.. ||| 
QIMNHPWM
Kinase CAMK1c-S3_b.AA DCAMKL 106-277 34 3.6e-39 119.12 In-house 104-279 (279) Show / Hide 
Range on Protein: 106-277
Range on HMM: 104-279/279
Sequence Identity: 34% (63 aa)

DRLKMVGRLADGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATDLHH-------LCGTPGYMSPDVLRAGEGGWPKYYT
| .  ...    .||  .  |.. |. .| ...|||| |.|| |.   .    ..|| ||| |.            |||| |  | .|.  | |    | 
DAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM--ETG----YG

QAVDVWGLGLILYELLSGRVAFPEYHSD--YVELLLKSVDNVEFALD---WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ||.| .| ||| || |   ||   |     | | . .   .| ..   |..... |||||  ||.| | .| | ||.. |||.
CKVDIWAAGVILYILLCG---FPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CAMK1c-S3_b.AA CAMK1 133-277 37 1.9e-38 109.35 In-house 124-276 (276) Show / Hide 
Range on Protein: 133-277
Range on HMM: 124-276/276
Sequence Identity: 37% (59 aa)

MHNLGVVHRDMKLENVLLTHPAQPYEVK--LSDFGVATDLHHL-------CGTPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELLSGRVAFPEYH
|| .|.|||| | || |.  .    ..|  ..||| .. . |        ||||||. |.||   .   .| | .|.|.|. | |.| || |   | .  
MHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK---DKPYDKACDMWSIGVITYILLCGYPPFYDEN

-SDYVELLLKSVDNVEFALD-WSDVTSE-AKDLIMGMLEVYPSRRLTVEQVLGHPWI
  ..   . |. . .||  . | .. .. |||.| .|||| |. |.|.||.| ||||
VDNELFEKIKKCE-YEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CAMK1c-S3_b.AA RSK 106-277 26 6.8e-38 132.21 In-house 90-278 (278) Show / Hide 
Range on Protein: 106-277
Range on HMM: 90-278/278
Sequence Identity: 26% (52 aa)

DRLKMVGR---LADGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTH-PAQPYEVKLSDFGVATDLHHL--------CGTPGYMSPDVLRAGEGGWP
..|.  ..   .   ||.|.   .. ... .| .|..||| |.||.|...   .. ..||.||| .  ..          |.|  || | .|. ..   .
THLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN--QQ

KYYTQAVDVWGLGLILYELLSGRVAFPEYHSD-YVELLLKSVDNVE--FALD-WSDVTSEAKDLIMGMLEVYPSRRLT-----VEQVLGHPWI
. ...|.|.| || ..||.|.|.. |     |   . ..| . . .  . .. |. .. |||||| .||.. |..||.     .|... |||.
GGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CAMK1c-S3_b.AA MSK 118-277 31 1.2e-37 124.81 In-house 102-277 (277) Show / Hide 
Range on Protein: 118-277
Range on HMM: 102-277/277
Sequence Identity: 31% (57 aa)

EAAFVTESLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDLHHL--------CGTPGYMSPDVLRA---GEGGWPKYYTQAVDVWGLG
|....  .|   .. || .|..|||.|.||.|..      .|||.||| |  .           |.|  ||.|..||    ..||    | .|.|.|.||
ECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGG----YDEACDWWSLG

LILYELLSGRVAFPEYHSDYV------ELLLKSVDNVEFALD---WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
 |||..|.|.| |    .|          . | .   || ..   |. .  .||||| ..|.. |..||...  . | |.
VILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase CAMK1c-S3_b.AA CAMK2 128-277 38 1.1e-31 104.69 In-house 109-259 (259) Show / Hide 
Range on Protein: 128-277
Range on HMM: 109-259/259
Sequence Identity: 38% (60 aa)

ETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDLH-------HLCGTPGYMSPDVLRAGEGGWPKYYTQAVDVWGLGLILYELLSGRVAFP
|..  .|. |.||||.| ||.||   ..   ||| |||.| ...          |||||.||.|||         | ..||.|  | ||| || |   | 
ESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK------DPYGKPVDIWACGVILYILLVGYPPFW

EYHSDYVELLLKSVDNVEFALDWSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
.     .   .|       . .|  || |||.||  || . |..|.| .. | ||||
DEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase CAMK1c-S3_b.AA Ciliate-E2a 95-220 32 4e-26 73.9 In-house 76-217 (275) Show / Hide 
Range on Protein: 95-220
Range on HMM: 76-217/275
Sequence Identity: 32% (47 aa)

LILELCSC-TLRDRLKMVGRLADG--EAAFVTESLA-ETLREMHNLGVVHRDMKLENVLLT--HPA--QPYEVKLSDFGVATDL--------HHLCGTPG
|..|.|.  .| |..|  .|.     |.. .   |  . |  ||.....||| |.||.|..   .   |. ..|..||| ||.         .  |||||
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMSPDVLRAGE--GGWPKYYTQAVDVWGLGLILYELLSGRVAFP
|. | ||   |   .  | |.. .|.| .|.|.| ||.|.  |.
YVAPEVLNNKEVLKH--KQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase CAMK1c-S3_b.AA Ciliate-E2a 242-277 43 1.4e-13 36.38 In-house 239-275 (275) Show / Hide 
Range on Protein: 242-277
Range on HMM: 239-275/275
Sequence Identity: 43% (16 aa)

D-WSDVTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
. |.....|.|||. .|||..|. |.| .| | ||| 
ECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CAMK1c-S3_b.AA TyrKc 25-277 18 1.4e-05 -132.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

YDVGFELGKGGQGTVHLVSFRMGGKLLAAKSFERSG----EREKEIMLKL-NGCHGTLEIYDMVEEEL------KGRWWGSLILELCSC-TLRDRLKMVG
   | .|| |  |.|..   .      | |.   .      || .|| ||       . .|  . ..       .  .   ...|...   |.|.|.  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLRKHR

R-LADGEAAFVTESLAETLREMHNLGVVHRDMKLENVLLTHPAQPYEVKLSDFGVATDLHHL--CGTPGYMSPDVLRAGE--GGW--------------P
. |   .        |.  .  |  ...|||    |.|....     || |||| . |...   .|     | |. |. |  ||                
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG----ESKDYYRKKEHKGGKTMLPIRWMAPECINY

KYYTQAVDVWGLGLILYELLSGRVAFPEYHS-----DYVELLLKSVDNVEFALDWSD--------VTSEAKDLIMGMLEVYPSRRLTVEQVLGHPWI
. .| . |||  |  ..|...     . |          . ... |.. .      .         ..|  ...    .  |. | | ...  |  .
GKFTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CAMK1c-S3_b.AA CAMKL 25-41 52 0.001067 7.51 In-house 1-17 (297) Show / Hide 
Range on Protein: 25-41
Range on HMM: 1-17/297
Sequence Identity: 52% (9 aa)

YDVGFELGKGGQGTVHL
|..| .||||. |.| |
YRIGKTLGKGSFGKVKL
Kinase CAMK1c-S3_b.AA Ciliate-E2 25-43 26 0.006192 5.89 In-house 1-19 (365) Show / Hide 
Range on Protein: 25-43
Range on HMM: 1-19/365
Sequence Identity: 26% (5 aa)

YDVGFELGKGGQGTVHLVS
|..   .|.|..|.| ...
YKFIKKIGQGNFGSVYKCK