CAMK1c-S5_t

Species: S.moellendorffii
Alias: CAMK1c-S5_t
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK1
Subfamily: CAMK1c

Sequence

Name Sequence Type Origin Length Description Download
CAMK1c-S5_t.AA Protein None 315 None Fasta, JSON
CAMK1c-S5_t.NA RNA None 948 None Fasta, JSON
CAMK1c-S5_t.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of CAMK1c-S5_t.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CAMK1c-S5_t.AA S_TKc 20-267 27 1.6e-59 205.01 SMART 1-231 (231) Show / Hide
Range on Protein: 20-267
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEARREASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELCGP---SLFDRLLKAGP-----
|. .. .| |. |.|.  .|..  ....| |. .    .||| .|. .   .| . .| ..  .      .  .|||.|.    .|||.. | |.     
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPREMAQCCGTGKYLAPEVIAIKFGKSSYTE-AVDVWGLGLI
 . | .|.. .. ... .. .||.||.||||||||..|         . |.|||.|.        .|||  |.||||.       .|.  ..|.| .| |
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCI

AYELLRGCT----EWRVMDLLRAGRFPDGLFSDGAADLLRGMLAVEPRKRTTLDRVLA-------HPWI
 ||.| |..    . .......         |. | |..|..| ..|.|| |   .|.       |||.
LYEMLCGYPPFPQMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CAMK1c-S5_t.AA CAMK 25-267 19 6.7e-53 168.42 In-house 1-425 (425) Show / Hide
Range on Protein: 25-267
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

RLGCGGQGQVFALTHRGFG-----------HKRYAGKMFRSS---------------------------------SEARREASIMDMLHA------CPGV
 || |. |.|.  .|.  .           ....| |.   .                                  . ||| .|| .|..       | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AHLEGFVKERDG----AQCY------------GSIVM---ELCGP-----SLFDRLLKAGP---------------MCEEDAARTIKKLAETIKEIHSRG
 .|  .   ..      . |              .||   |.|        |||.. . |.               ..|..|.| .. ... .. .||..
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENVFLKLDAAAAD-------------DVVIGDFGMATDDPR--------------------------EMAQCCGTGKYLA-PEVIAIKFGKS
||||||||||. |  .    |             .. | |||.|.  ..                           |  .|||  | | |||.  | ...
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

S----------YTEAVDVWGLGLIAYELLRGCTEWRVMD-------------------LLRAGRF--PDGLFSD-----------------------GAA
.          |....|.| .| | | .| |.  ..  .                     ..|..  |.  ||.                        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLRGMLAVEPRKRTTLDRVLAHPWI
||.|.|| |.| || |.. .|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Pkinase CAMK1c-S5_t.AA Pkinase 20-267 25 8.7e-44 155.9 Pfam 1-293 (293) Show / Hide
Range on Protein: 20-267
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEAR---------REASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELCGP-----SLFDR
|..|...| |. |.|.  .|.| |. ..| | .. ..|           .|..|| .|. .| .  | ... .  .  .|  .|||.|.      .|||.
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDY

LL--KAGPM--CEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMA----TDDPREMAQCCGTGKYLAPEVIAIKFGKSSY
.   . |..   |... . .. ... .. .||.||.||||||||.... .   ...| |.||| |    .   . |   |||  |.|||||    | . |
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYY

TEAVDVWGLGLIAYELLRGCTEWR------------VMDLLRAGRFPDGLF----------------------SDGAADLLRGMLAVEPRKRTTLDRVLA
. .||.|..|.| ||.| | . ..            .... . ....   .                      |. . |.....|.. | || | . .| 
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPWI
|||.
HPWF

Kinase CAMK1c-S5_t.AA AGC 93-267 19 4.8e-39 97.37 In-house 110-395 (395) Show / Hide
Range on Protein: 93-267
Range on HMM: 110-395/395
Sequence Identity: 19% (59 aa)

IVMELC-----------GPSLFDRLL---KAGPMCEEDAARTIKK-------LAETIKEIHS-RGIVHRD-LKPENVFLKLDAAAADDVVIGDFGMATDD
.|||..           |  || .|    | | . || |   .         ..  .  .|| .||.||| |||||. |  |      . . |||...  
FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED----GHIKLTDFGLCKEG

PRE-----------------------------------------------------MAQCCG--TGKYLAPEVIAIKFGKSSYTEAVDVWG--LGLIAYE
...                                                         ||  |  |.|||..        |. |.| |.  || . ||
MNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------YGKACDWWSFGLGCLMYE

LLRG--------------------CTEWRVMDLLRAGRFPDGL-------------FSDGAADLLRGMLAVEPRKRTT----------LDRVLAHPWI
.| |                     .  ..|.  ..  ..  .             ||. | ||....| ..|.|| .           . . .||| 
MLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase CAMK1c-S5_t.AA Ciliate-E2a 93-218 35 4.3e-37 106.73 In-house 76-214 (275) Show / Hide
Range on Protein: 93-218
Range on HMM: 76-214/275
Sequence Identity: 35% (49 aa)

IVMELC-GPSLFDRLLKAGPMCEE--DAARTIKKLA-ETIKEIHSRGIVHRDLKPENVFLK-LDAAAA--DDVVIGDFGMATDD----PREMAQCCGTGK
.|||.| | .|.|.. . . . ||  .... ...|  . .  .|.|.|.||||||||...| ...  .   |..| |||.||.     .. | | |||  
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YLAPEVIAIKF--GKSSYTEAVDVWGLGLIAYELLRGCT
|.||||...|    . .|.. .|.| .|.| | || |..
YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKP

Kinase CAMK1c-S5_t.AA Ciliate-E2 93-267 21 1e-36 123.59 In-house 111-365 (365) Show / Hide
Range on Protein: 93-267
Range on HMM: 111-365/365
Sequence Identity: 21% (57 aa)

IVMELC-GPSLFDRLL------------KAGPMCEEDAARTIKKLAE---------------TIKEIHSRG-IVHRDLKPENVFLKLDAAAADDVVIGDF
.|||.| | .|||..             . ... |. ... .|....                ....||.. |.|||.||||...         . | ||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDF

GMAT--DDPREMAQ--------------------------------CCGTGKYLAPEVIAIKF-----GKSSYTEAVDVWGLGLIAYELLRGCTEWRVMD
|...  ||.... .                                .|||  |.|||..  |      ..  |....|.| || | ||.| | . .  ..
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQ

LLRAGRFP-DGL------------------FSDGAADLLRG----MLAVEPRKRTT-LDRVLAHPWI
    . .  .                     |. . ||..     || ..| || |  . .| |||.
QIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CAMK1c-S5_t.AA CAMKL 93-267 28 9.3e-34 104.99 In-house 98-297 (297) Show / Hide
Range on Protein: 93-267
Range on HMM: 98-297/297
Sequence Identity: 28% (60 aa)

IVMELCGPS---LFDRLLKA----GPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMAT--DD-----PREMAQCCG
.|||.|.     |||.. |     |.| |..| |  . . . .. .||.||||||.||||. |  .      . | |||...  ..      . .  .||
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TGKYLAPEVIAIKFG--KSSYTEAVDVWGLGLIAYELLRGCTEWRV-------------MDLLRAGRFPDGLF---SDGAADLLRGMLAVEPRKRTTLDR
.  | |||...   |  |. .  .||.| .| | | .. |   ..              .   . | . .  .   |  . ||.|.|| | | || |.. 
SPPYMAPEIFQ---GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

VLAHPWI
.. ||| 
IMNHPWM

Kinase CAMK1c-S5_t.AA CAMK1 93-217 40 1.4e-30 86.09 In-house 85-213 (276) Show / Hide
Range on Protein: 93-217
Range on HMM: 85-213/276
Sequence Identity: 40% (53 aa)

IVMELC-GPSLFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVV--IGDFGMA--TDDPR-EMAQCCGTGKYLAPE
.||||. |  |||| .. |   |.||....|.... .. .||.|||||||||||  .. |     ...  | ||| .  .|.    | ..|||  | |||
LVMELVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYY-DKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPE

VIAIKFGKSSYTEAVDVWGLGLIAYELLRGC
|.. |     |  |.|.|. | | | || |.
VLECKK-DKPYDKACDMWSIGVITYILLCGY

Kinase CAMK1c-S5_t.AA MSK 24-217 28 6.2e-29 94.93 In-house 2-207 (277) Show / Hide
Range on Protein: 24-217
Range on HMM: 2-207/277
Sequence Identity: 28% (61 aa)

KRLGCGGQGQVFALTHRGFGHKR---YAGKMFR---------SSSEARREASIMDMLHACPGVAHLEGFVKERDGAQCYGSIVMELC-GPSLFDRLLKAG
| || ||.| .| . ..  .|.    || |  .           .....|...  |.  .| . .| .  ..    ||   .|||.| |. || .. | .
KVLGTGGYGKFF-ICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQD----QCHTYLVMEYCNGGELFTHIRKRE

PMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPRE---MAQC-CGTGKYLAPEVIA-IKFGKSSYTEAVDVWG
 . |. ..  . .|   .. .|..||.||||||||. .  .   .  |.. ||| |   |..    ..  |.|  | |||...    ... | ||.|.|.
HFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNG-HVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWS

LGLIAYELLRGC
|| | |..| |.
LGVILYTMLTGQ

Kinase CAMK1c-S5_t.AA RSK 93-218 29 4.8e-28 99.5 In-house 78-210 (278) Show / Hide
Range on Protein: 93-218
Range on HMM: 78-210/278
Sequence Identity: 29% (40 aa)

IVMELC-GPSLFDRLLKAGP---MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATD-DPR--EMAQC-CGTGKYLA
..||.| |. ||..|.| .    ..|..|.  . ... ... .|..||.||||||||. .  .      ... ||| .   ...  ....  |.|  |.|
LIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEVIA-IKFGKSSYTEAVDVWGLGLIAYELLRGCT
||...  . ... ...|.|.| || . ||.| ||.
PEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCP

Kinase CAMK1c-S5_t.AA DCAMKL 102-216 33 8.9e-24 70.37 In-house 102-215 (279) Show / Hide
Range on Protein: 102-216
Range on HMM: 102-215/279
Sequence Identity: 33% (40 aa)

LFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPR---EMAQCCGTGKYLAPEVIAIKFGKSSYT
||| . . .   | |||. . .|.. .| .|...|||||.||||  .. .      .  .||| |.  ..    .   |||  | |||...    .  | 
LFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM----ETGYG

EAVDVWGLGLIAYELLRG
  ||.| .| | | || |
CKVDIWAAGVILYILLCG

Kinase CAMK1c-S5_t.AA RSK 93-218 36 9.4e-23 78.16 In-house 78-203 (271) Show / Hide
Range on Protein: 93-218
Range on HMM: 78-203/271
Sequence Identity: 36% (48 aa)

IVMELC-GPSLFDRLLKAGPMCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMA--TDDPREMAQC-CGTGKYLAPEVI
..|... |  ||||||| . ..|....     .| .    || |||||||||||. .  . . .. . | ||| |    |  .|.   |.|  |.||||.
MIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVL

AIKFGKSSYTEAVDVWGLGLIAYELLRGCT
     .  ...|.|.| .| . || | |||
K----RQGHDQACDWWSFGVLMYEMLTGCT

Kinase CAMK1c-S5_t.AA CAMK1 237-267 50 7.6e-11 27.69 In-house 245-276 (276) Show / Hide
Range on Protein: 237-267
Range on HMM: 245-276/276
Sequence Identity: 50% (16 aa)

SDG-AADLLRGMLAVEPRKRTTLDRVLAHPWI
||. | |....|| |.| || | . .|.||||
SDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase CAMK1c-S5_t.AA DCAMKL 237-267 48 2.3e-10 27.88 In-house 249-279 (279) Show / Hide
Range on Protein: 237-267
Range on HMM: 249-279/279
Sequence Identity: 48% (15 aa)

SDGAADLLRGMLAVEPRKRTTLDRVLAHPWI
||.| || . || |.| || |   ...|||.
SDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase CAMK1c-S5_t.AA RSK 237-267 38 7.6e-09 27.94 In-house 236-271 (271) Show / Hide
Range on Protein: 237-267
Range on HMM: 236-271/271
Sequence Identity: 38% (14 aa)

SDGAADLLRGMLAVEPRKRTTL-----DRVLAHPWI
|| | ||||.|| . | .| .       ... |||.
SDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase CAMK1c-S5_t.AA RSK 237-267 36 7.8e-09 28.8 In-house 243-278 (278) Show / Hide
Range on Protein: 237-267
Range on HMM: 243-278/278
Sequence Identity: 36% (13 aa)

SDGAADLLRGMLAVEPRKRTT-----LDRVLAHPWI
|. | ||.|.|| ..| || .     ......|||.
SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CAMK1c-S5_t.AA TyrKc 20-267 22 8.8e-09 -80.67 SMART 1-280 (280) Show / Hide
Range on Protein: 20-267
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEAR----REASIMDML-HACPGVAHLEGFVKER------DGAQCYGSIVMELCGP-SLFDRLL
 . || ||.|  |.|.  | .       | || ....  |    |||.|| .|    | .  | | . .       ..  .   ||||..   .| |.| 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM---IVMEYMPHGDLKDYLR

KAGP-MCEEDAARTIKKLAETIKEIHSRGIVHRDLKPENVFLKLDAAAADDVVIGDFGMATDDPRE--------MAQC----CGTG----KYLAPEVIAI
| .|  | .|        |.    .||....||||   |. .. .      | |.|||.. |   .        .       .| .    . .|||.|  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

KFGKSSYTEAVDVWGLGLIAYELL-------RG-----CTEWRVMDLLRAG---RFPDGL-------FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI
..||  .|.. |||  |   .|..        |     ..  .|. ....|   . |.          .|   .. .   . .| .| |   .  |  .
NYGK--FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase CAMK1c-S5_t.AA Ciliate-E2a 236-267 40 1.3e-07 18.51 In-house 244-275 (275) Show / Hide
Range on Protein: 236-267
Range on HMM: 244-275/275
Sequence Identity: 40% (13 aa)

FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI
.|. . ||...|| . | || |    | ||| 
CSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase CAMK1c-S5_t.AA MSK 236-267 34 5e-06 16.44 In-house 246-277 (277) Show / Hide
Range on Protein: 236-267
Range on HMM: 246-277/277
Sequence Identity: 34% (11 aa)

FSDGAADLLRGMLAVEPRKRTTLDRVLAHPWI
.|  | ||....| . | || ...  .|| |.
MSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK

Kinase CAMK1c-S5_t.AA CAMKL 20-69 27 0.037421 2.5 In-house 1-70 (297) Show / Hide
Range on Protein: 20-69
Range on HMM: 1-70/297
Sequence Identity: 27% (19 aa)

YKRGKRLGCGGQGQVFALTHRGFGHKRYAGKMFRSSSEA--------------------RREASIMDMLH
|. || ||.|. |.|   ||. .  ...| |.   .                       |||..|| ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN

Kinase CAMK1c-S5_t.AA Ciliate-E2 20-40 33 0.068237 2.26 In-house 1-21 (365) Show / Hide
Range on Protein: 20-40
Range on HMM: 1-21/365
Sequence Identity: 33% (7 aa)

YKRGKRLGCGGQGQVFALTHR
||  | .| |..|.|.  ...
YKFIKKIGQGNFGSVYKCKVW