Gene CK1x_b (S.moellendorffii)

CK1x_b

Species: S.moellendorffii
Alias: CK1x_b
External Links:
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1x

Sequence

Name Sequence Type Origin Length Description Download
CK1x_b.AA Protein None 691 None Fasta, JSON
CK1x_b.NA RNA None 2076 None Fasta, JSON
CK1x_b.kin_dom Protein Kinase Domain None 147 None Fasta, JSON

Protein domain

Protein domains of CK1x_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK1x_b.AA CK1 256-399 40 3.4e-47 160.53 In-house 126-271 (271) Show / Hide 
Range on Protein: 256-399
Range on HMM: 126-271/271
Sequence Identity: 40% (60 aa)

YVHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN
..| |.||.||| || .  .....|..| ||| . .|  |..|. |      . ||.||||. .|||.  |||||.|||.| |...||| ||||| . ..
FIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKN-LTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANT

KG---FLVCKKKMATSPESLCCF-CPAPFKEFLEAVVSMKFNEEPNYA
|       . ||| |..| ||   .|. | ..|. . ...|.|.|.|.
KKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase CK1x_b.AA CK1 256-401 29 2.9e-46 159.34 In-house 153-339 (339) Show / Hide 
Range on Protein: 256-401
Range on HMM: 153-339/339
Sequence Identity: 29% (56 aa)

YVHGDVKPENFLLGRPGS-----------PDEKKLYLVDLGLAT-KWLDG-----------TTGSHVDYDQ--RPDVFRG-TVRYASVHAHLGRTGSRRD
..| |.||.||..|| .|           ......|..| |.|  | .|             |. |  .        ||| |.||.|...|||.  .|||
FIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRD

DLESLAYTLIFLLRGR--LPWQGYQGDNKGFL-----VCKKK------MATSPESLCCF-----CPAPFKEFLEAVVSMKFNEEPNYAKL
||.|..|.|| .|.|   ||||.    .|.       . |..      | |... |||      ||  | .... . |.|. ..|.|...
DLWSWFYMLIEWLKGTPGLPWQNMKDEMKP-KDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase CK1x_b.AA CK1-G 246-401 38 1.1e-41 138.99 In-house 101-266 (266) Show / Hide 
Range on Protein: 246-401
Range on HMM: 101-266/266
Sequence Identity: 38% (64 aa)

VALYLMFRCRYVH------GDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLI
||  .. | .|||      .||||.||| |||...|.......| |.| .. |  |. |. |  .     || || |.  ||||  |||||.|.|    .
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREH-KSLTGTARYMSINTHLGREQSRRDDMEALGHMFM

FLLRGRLPWQGYQGDN---KGFLVCKKKMATSPESLCCF--CPAPFKEFLEAVVSMKFNEEPNYAKL
. ||| |||||   ||   .   . ..| .| .| ||     |  |  .|. | ...|.|.| |  |
YFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase CK1x_b.AA CK1-Unclassified 253-356 44 2.2e-39 113.91 In-house 122-224 (244) Show / Hide 
Range on Protein: 253-356
Range on HMM: 122-224/244
Sequence Identity: 44% (47 aa)

RCRYVHGDVKPENFLLG-RPGSPDEKKLYLVDLGLATKWLDG-TTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQG
.. ..| | ||.||| | . .    ...|..|.||. . .|   ||.|..|.   . . || ||||. ||||   |||||||||.|.||..|.|.||||.
NKNFIHRDIKPDNFLMGKLGKN--HHQVYIIDFGLSKRYIDMDKTGKHIPYRENKN-LTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQN

YQGDNK
 . .||
IKANNK
Kinase CK1x_b.AA CK1-A 256-401 40 7.2e-37 127.75 In-house 116-261 (261) Show / Hide 
Range on Protein: 256-401
Range on HMM: 116-261/261
Sequence Identity: 40% (61 aa)

YVHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN
..| |.||.|||.|        ||.|.| ||| |. |  |  |. | .  ..  ||.||||..||||   |||||.||..| ...  ||.||||| .  .
FIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLT-GTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMT

KGFL---VCKKKMATSPESLCCFCPAPFKEFLEAVVSMKFNEEPNYAKL
|      .  |||.|. | ||   || |  ... . ...|.|.|.|  |
KKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase CK1x_b.AA CK1-D 256-401 39 4.6e-36 124.67 In-house 116-261 (261) Show / Hide 
Range on Protein: 256-401
Range on HMM: 116-261/261
Sequence Identity: 39% (60 aa)

YVHGDVKPENFL--LGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQG
..| |.||.|||  ||. |.      |..| ||| .. |  |  |. |        || ||||.  |.|   ||||||||| | |..  || ||||| . 
FIHRDIKPDNFLMGLGKRGN----MVYIIDFGLAKRYRDARTHQHIPYREN-KNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKA

DNKGF---LVCKKKMATSPESLCCFCPAPFKEFLEAVVSMKFNEEPNYAKL
 .|      .| ||| |. . ||   |  |..... . ..||.. |.|. |
ATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase CK1x_b.AA TTBKL 256-405 25 1.1e-27 90.63 In-house 123-288 (288) Show / Hide 
Range on Protein: 256-405
Range on HMM: 123-288/288
Sequence Identity: 25% (45 aa)

YVHGDVKPENFLLGRPG--SPDEKKLYLVDLGLATKWL--DGTT----------------GSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLA
..| |||| |. .|  .  ..... .||.| |.| ...  || .                .      .    ||||.||.|. .|...  .| ||| |. 
FIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNF------RHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWM

YTLIFLLRGRLPWQGYQGDNKGFLVCKKKMATSPESLC--CF----CPAPFKEFLEAVVSMKFNEEPNYAKLILLF
|..| |. | |||   .. ..   . ..|.... | |.  ..    ||  | .| ... |......|.| ... .|
YMIIELHCG-LPW---TNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase CK1x_b.AA Worm6 256-401 25 1.1e-23 82.02 In-house 125-279 (279) Show / Hide 
Range on Protein: 256-401
Range on HMM: 125-279/279
Sequence Identity: 25% (40 aa)

YVHGDVKPENFLLGR---PGSPDEKKLYLVDLGLAT--KWLDGTTGSHVDYDQR-PDV-FRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW
..| |||| ||  ||     . .....|..| |..   | ..  .   . . .| ... ||||||||....| |.  .|.||.||  | .. ...|.|||
FIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGN---ELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPW

QGYQGDNKGFLVCKKKMATSP---ESLCCF-CPA-PFKEFLEAVVSMKFNEEPNYAKL
..  ...    . |... .     ...  . ||.  |.. .. . .... ..|.|...
RHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase CK1x_b.AA TTBK 256-401 34 4.8e-23 78.3 In-house 118-257 (257) Show / Hide 
Range on Protein: 256-401
Range on HMM: 118-257/257
Sequence Identity: 34% (50 aa)

YVHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDN
. | |.|| || .||  |   .| |..| ||| ... ..    |        |||||||||. ||. |   |.||| || | |.  . | |||      .
FLHRDIKPSNFAMGRNPS-TCRKCYMLDFGLARQYTNACG--EVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKD

KGFLVCKKKMATSPESLCCFCPAPFKEFLEAVVSMKFNEEPNYAKL
.   | . |       |   ||  |. |.. . |... . |.|. .
Q---VGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase CK1x_b.AA CK1-Unclassified 161-242 32 5.2e-15 40.75 In-house 1-82 (244) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-82/244
Sequence Identity: 32% (30 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGP-NAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGGKH-------GIPKVHFKGRQ--GDYFIMV
||  .|.| | ||..| .        .   .  |||.|.| . ||  .   .|| ... .| . |       ||||..  |..  ||| |||
YRVIEKIGQGSFGEIYKC--------INMQTNEEVAIKLEKKNSK--HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMV
Kinase CK1x_b.AA VRK 256-348 42 6.6e-15 44.59 In-house 151-240 (284) Show / Hide 
Range on Protein: 256-348
Range on HMM: 151-240/284
Sequence Identity: 42% (41 aa)

YVHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFR---GTVRYASVHAHLGRTGSRRDDLESLAYTLIFLLRGRLPW
|||||.| .| |||     .  . |||| ||| .  ..  | |..|   .|  |   ||  . |  ||.|   ||| |||.|.| ..  | | |||
YVHGDIKAANILLGFE--KNPDQVYLVDYGLAYRYCPN--GKHRQY--KEDPRRCHNGTCEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW
Kinase CK1x_b.AA CK1 161-242 36 1.2e-14 46.99 In-house 1-83 (271) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-83/271
Sequence Identity: 36% (33 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGG------KHGIPKVHFKGRQ--GDYFIMV
||  ||.| | ||..| |  .  |        .|| |.| . ||  ..  .|| ..|  | |       ||||...  |..  ||| |||
YRVGRKIGQGSFGDIYLGINMTNGEE----N-HVAIKLEKNKSK--HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMV
Kinase CK1x_b.AA CK1-D 161-242 34 1.1e-12 40.87 In-house 1-73 (261) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-73/261
Sequence Identity: 34% (28 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGGKHGIPKVHFKGRQGDYFIMV
||  ||.| | ||..| | ..  ..       |||.| |   .|       .| ..|  . |  |||.... |..||| .||
YRIGRKIGSGSFGDIYHGTNIQTNE-------EVAIKLECIKTKHPQLH--IESKFYKMMQGGIGIPEIRWCGQEGDYNVMV
Kinase CK1x_b.AA CK1 161-242 23 8.8e-12 37.46 In-house 1-107 (339) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-107/339
Sequence Identity: 23% (26 aa)

YRTDRKLGKGGFG-QVYVGRKLGPGDLTGPNA------VEVALKFEHRSSKGCNYGPPYEWQVYDNLGG--------------------KHGIPKVHFKG
..  .|.|.|||| |.| ..|    | .  .        |.|.| |...|.| ..   .| |.|  | |                    .. .......|
WKVVKKIGEGGFGYQIYKVQKE---DHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHG

RQGDYF-IMV
...||. .||
EEDDYYNYMV
Kinase CK1x_b.AA CK1-A 161-242 36 2.3e-10 32.65 In-house 1-73 (261) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-73/261
Sequence Identity: 36% (30 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGGKHGIPKVHFKGRQGDYFIMV
||  ||.| | || .|.| ..  |.       |||.| | .  .       || .||  | |  |||.... |.. || .||
YRLVRKIGSGSFGDIYLGINITNGE-------EVAIKMESNKARHPQLI--YEAKVYRILQGCVGIPHMRWYGCEKDYNVMV
Kinase CK1x_b.AA Pkinase 257-371 22 3.2e-09 33.69 Pfam 130-238 (293) Show / Hide 
Range on Protein: 257-371
Range on HMM: 130-238/293
Sequence Identity: 22% (27 aa)

VHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYASVHAHL-GRTGSRRDDLESLAYTLIFLLRGRLPWQGY----
.| |.||||.|. . | .|. .. . | ||| .            .. ...| || .|..   .. |.  ... |  |.  .|. .| ||.|..|     
IHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHD

QGDNKGFLVCKKKMATSPES
  ... ...|.....  ...
N-HDQMQMICRIMGPPLHFD
Kinase CK1x_b.AA CK1-G 161-242 33 1.2e-08 25.38 In-house 1-74 (266) Show / Hide 
Range on Protein: 161-242
Range on HMM: 1-74/266
Sequence Identity: 33% (28 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGGKH-GIPKVHFKGRQGDYFIMV
||  .| | | || .. |. .          . || ||| . |.        |.. |  |.|.  |||.|.. |  | | |||
YRVGKKIGCGNFGELFEGKNMYN-------NEHVAIKFEPMKSRAPQLH--DEYRFYKILNGCPEGIPQVYYFGQCGKYNIMV
Kinase CK1x_b.AA S_TKc 161-423 18 2.3e-08 -54.16 SMART 1-220 (231) Show / Hide 
Range on Protein: 161-423
Range on HMM: 1-220/231
Sequence Identity: 18% (56 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCNYGPPYEWQVYDNLGGKHGIPKVHFKGRQGDYFIMV---GVG----VALYLMFR
|.  ||.|||.||.|| .|. .          .||.|  .            | |.  .  .   | | .   .  |.. ||     |    .  |.  |
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

CR-----------------------------YVHGDVKPENFLLGRPGSPDEKKLYLVDLGLATKWLDGTTGSHVDYDQRPDVFRGTVRYAS--VHAHLG
 |                              .| |.|||| || .        . . | |||..                . | ||  | .  |     
GRHGLRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----

RTGSRRDDLESLAYTLIFLLRGRLPWQGYQGDNKGFLVCKKKMATSPESLCCFCPAPFKEFLEAVVSMKFNEEPNYAKLILLFDSILG-LPAQRPINTEC
  | .. |  |.  .|. .| |. |..        ... || .                                   .. . . .|   |..||   |.
GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

AT
 .
LQ
Kinase CK1x_b.AA TTBKL 161-182 36 5e-06 16.48 In-house 1-22 (288) Show / Hide 
Range on Protein: 161-182
Range on HMM: 1-22/288
Sequence Identity: 36% (8 aa)

YRTDRKLGKGGFGQVYVGRKLG
..  ...|.||||||| .. ..
WMIVKMIGEGGFGQVYHVWDMK
Kinase CK1x_b.AA Pkinase 161-207 29 2e-05 20.27 Pfam 1-40 (293) Show / Hide 
Range on Protein: 161-207
Range on HMM: 1-40/293
Sequence Identity: 29% (14 aa)

YRTDRKLGKGGFGQVYVGRKLGPGDLTGPNAVEVALKFEHRSSKGCN
|.. ||.|.|.||.|| ... | |.       .||.|   .... ..
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVKIIKKRHEKSW
Kinase CK1x_b.AA Worm6 161-177 47 0.00063 10.37 In-house 1-17 (279) Show / Hide 
Range on Protein: 161-177
Range on HMM: 1-17/279
Sequence Identity: 47% (8 aa)

YRTDRKLGKGGFGQVYV
.  ..|.|.|||| ||.
WKVTKKIGEGGFGAVYK
Kinase CK1x_b.AA CK1-Unclassified 363-373 54 0.003174 5.39 In-house 234-244 (244) Show / Hide 
Range on Protein: 363-373
Range on HMM: 234-244/244
Sequence Identity: 54% (6 aa)

KKMATSPESLC
.|| |..|.||
MKMSTPVEQLC
Kinase CK1x_b.AA TTBK 161-181 33 0.035233 3.54 In-house 1-21 (257) Show / Hide 
Range on Protein: 161-181
Range on HMM: 1-21/257
Sequence Identity: 33% (7 aa)

YRTDRKLGKGGFGQVYVGRKL
 .  .| | |||| .| .  .
WKVVKKIGGGGFGEIYEAKDM
Kinase CK1x_b.AA VRK 161-176 43 0.135874 1.38 In-house 1-16 (284) Show / Hide 
Range on Protein: 161-176
Range on HMM: 1-16/284
Sequence Identity: 43% (7 aa)

YRTDRKLGKGGFGQVY
.|  .. |.||||  |
WRLGKPIGQGGFGCIY