Gene PEKa (S.moellendorffii)

PEKa

Species: S.moellendorffii
Alias: PEKa
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: GCN2

Sequence

Name Sequence Type Origin Length Description Download
PEKa.AA Protein None 819 None Fasta, JSON
PEKa.NA RNA None 2460 None Fasta, JSON
PEKa.kin_dom Protein Kinase Domain None 306 None Fasta, JSON

Protein domain

Protein domains of PEKa.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PEKa.AA PEK 216-416 32 2.6e-74 253.19 In-house 358-655 (655) Show / Hide 
Range on Protein: 216-416
Range on HMM: 358-655/655
Sequence Identity: 32% (96 aa)

LYIQMEYCP-RTLREVFDTRS--------------------------------------------VLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSN
||||||||.  |||   | ..                                             .||.. | |||||.||| .||.||.|||||.|||
LYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSN

IFFDTRND-----VKIGDFGLGV---------------------------CAAKFADLQNPDQDHRVPVKFEAN----------VKSLEGTGQVGTYFYR
||.|  ..     ||||||||                             | ... . ||  .... . .  .|            ... ||.|||..|.
IFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMW-SNNYHIQPTSMFYCEHCHHTGGVGTCLYM

APEIE--Q--AWPHIDEKVDMYSLGVILFELWHPFSTGM-ERYVTLNELKQ------QNILPSNWAAKFPHQAALVHLLVSPHPQDRPSARDVLQSELL
.|| .  |     | ..||||||||.|.||.|.||.| | ||. ||. |..      . . |.... |.| || ......|. ||.|||| . ||.|..
SPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase PEKa.AA GCN2 189-416 33 8.8e-72 244.78 In-house 241-511 (511) Show / Hide 
Range on Protein: 189-416
Range on HMM: 241-511/511
Sequence Identity: 33% (91 aa)

GEESEISSSWVDTAGSSSNDVNTVST--------------FLYIQMEYCP-RTLREVFDTR-SVLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIF
.|.. ....  .  ...... .. ..               ||||||||. .|||.  |    ..|..  | .||||.|||..|| ||.||||| |||||
AESEDQNKKKSQQQDKMCQNQHKNKVHYKCMNCKKPKEVHYLYIQMEYCEGKTLRQYIDNHGWCMDHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIF

FDTRNDVKIGDFGLGVC---------------------AAKFADLQNPDQDHRVPVKF---EANVKSLEGTGQVGTYFYRAPEIEQAWPHIDEKVDMYSL
.|  ..||||||||                         | ..... .||    ...|   . .  ... || |||.||..||..    | ..|||||||
LDCCGNVKIGDFGLATNNKMESQINRKQQKQQQQASSHWAIQNEICQDDQFNQQQSQFSQWDQQDEQVHHTGKVGTPFYMCPEQQ--KSHYNQKVDMYSL

-GVILFELWHP-FSTGMERYVTLNELKQQNILPSNWAA----KFPHQAALVHLLVSPHPQDRPSARDVLQSELL
 |.|.||.|.| |.|.|||. .|..|.  . .|..  .    . . |. ... .... || ||||.. ||.|.|
GGIIFFEMWYPPFCTQMERVQILKQLR-SCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL
S_TKc PEKa.AA S_TKc 111-416 22 5.4e-61 209.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-416
Range on HMM: 1-231/231
Sequence Identity: 22% (74 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPSDKILREVATLSRLQHQHVVRYYQAWFETAAGGSSGTPYGEESEISSSWVDTAGSSSNDVN
.| | ..|||.|| | .|..| .||..|.|..|       ..|.||.. |.. .| ..|..| .. .                                 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---------------------------------

TVSTFLYIQMEYCPR---TLREVFDTRSV------LDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRNDVKIGDFGLGVCAAKFADLQNPDQ
   ..||. ||||.    .|... . |        ..   .. ...||...| ..| .||||||| |.||..|.   .||.||||               
---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------

DHRVPVKFEANVKSLEGTGQVGTYFYRAPEIEQAWPHIDE-KVDMYSLGVILFELWH---PFSTGMERYVTLNELKQQNILPSNWAAKFPHQAALVHLLV
                 | ..|| .|.|||.     . .  |.|..|.|.||.|.     ||.   . ..... ..             |    ..  . 
-----------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCL

SPHPQDRPSARDVLQ-------SELL
   |..||.| ..||        . .
QKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase PEKa.AA Pkinase 111-355 25 3.7e-49 174.43 Pfam 1-205 (293) Show / Hide 
Range on Protein: 111-355
Range on HMM: 1-205/293
Sequence Identity: 25% (66 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPSDKIL----REVATLSRLQHQHVVRYYQAWFETAAGGSSGTPYGEESEISSSWVDTAGSSS
.. .  .|.|.|| | .|..| .|...|.|..|...|... ..     .|.. . ||.| ..||.| .. .                             
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----------------------------

NDVNTVSTFLYIQMEYCPRTLREVFDTR---S-----VL--DKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRNDV----KIGDFGLGVCAAK
      .. .|. ||||. .|  |.|     |     ..  . .    ...||..|| ..| .||||||| |.||..| ....    ||.||||  ..  
------KDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-

FADLQNPDQDHRVPVKFEANVKSLEGTGQVGTYFYRAPEIEQAWPHIDEKVDMYSLGVILFEL
                   . ..   |. .||..|.|||. .  .... ||||.|.|.||.|.
-------------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEM
Kinase PEKa.AA CAMK 116-353 17 9.3e-43 135.15 In-house 1-325 (425) Show / Hide 
Range on Protein: 116-353
Range on HMM: 1-325/425
Sequence Identity: 17% (63 aa)

LLGKGGFGHVVLCKNKLDG------------RRYAMKKVKLK----------------------------DENPSDKILREVATLSRLQ-------HQHV
 ||.|.|| | ||..|...            ...|.| .. |                            ...  ....||.. ...||       | ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYQAWFE-----------TAAGGSSGTPYGEESEISSSWVDTAGSSSNDVNTVST---FLYIQM---EYCPRT-----LREVFDTR------------
.. |...             |   .                            .. |   ..|. |   |||.       | .    .            
IKLYEVYEDPHYFKNTNDYET-SKQ----------------------------VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDI

---SVLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTR-----------------NDVKIGDFGLGV-CAAKFADLQNPDQDHRVPVKFEANV
     .. . .  .||||.... ..| ..|.|||| | || .|..                 |..|| |||.   .  .  .....|....  .  .   
VERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN---

KSLEGTGQ-------------VGTYFYRA-PEIEQA-------------WPHIDEKVDMYSLGVILF
       |             .||  | | ||. .               | ...|.|| |.||||.
-------QWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase PEKa.AA HRI 245-416 39 2.6e-35 121.83 In-house 438-613 (613) Show / Hide 
Range on Protein: 245-416
Range on HMM: 438-613/613
Sequence Identity: 39% (72 aa)

IFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRND----VKIGDFGLGVCAAKFADLQNPDQDHRVPVKFEANVKSLEG------TGQVGTYFYRAPE-IE
|| |||||.  ||. .|.|||..| |||   . .    ||||||||    |    ||.|    |     ..   . ..      |  |||  | .||  .
IFQQIVEGMFYIHNMFIVHRDVKPRNIFLHDPDQGHPQVKIGDFGL----ACEDILQEPKTPMRFRRDQDFDWTNRNPCVTQTHTSRVGTCTYASPEQLD

QAWPHIDEKVDMYSLGVILFELWHPFSTGMERYVTLNELKQQNILPSNWAAKFPHQAALVHLLVSPHPQDRPSARDVLQSELL
      | | ||||.|||||||. || | |||   |  ..   | |     . | ||  . .|       ||||  .||||| 
GS--QYDNKSDMYSMGVILFELFQPFGTEMERAEVLTGVRTGQI-PESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF
Kinase PEKa.AA PKR 111-286 36 1.1e-34 121.6 In-house 1-169 (272) Show / Hide 
Range on Protein: 111-286
Range on HMM: 1-169/272
Sequence Identity: 36% (66 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPSDKILREVATLSRLQHQHVVRYYQAWFETAAGGSSGTPYGEESE---ISSSWVDTAGSSSN
|... ..| |||| |   | ..||.||..|.||   |    |  .||  | .|.|  .|.|   |         |  |  |     . ||  |    ...
FKDIEEIGSGGFGQVFKAKHRIDGKRYVIKRVKYNNE----KAEHEVQALAKLDHVNIVHYHSCW--------DGFDYDPEHSDDSLESSDYDPE-NMKD

DVNTVSTFLYIQMEYCPR-TLREVFDTR--SVLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRNDVKIGDFGL
        |.||||.| . ||      |  . .|| |   .. |||.|   || ...||||| |||||      .|||||||
TSRYKTRCLFIQMEFCDKGTLEQWMRNRRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPSNIFLVDERHIKIGDFGL
Kinase PEKa.AA PEK 111-178 43 1.4e-34 117.4 In-house 1-86 (655) Show / Hide 
Range on Protein: 111-178
Range on HMM: 1-86/655
Sequence Identity: 43% (37 aa)

FEELCLLGKGGF-GHVVLCKNKLDGRRYAMKKVKLKDEN-----------------PSDKILREVATLSRLQHQHVVRYYQAWFET
|||...|||||| | |. ..|||||..|| |..||.. .                  ..|.|||| ||.||.|...|||..||.|.
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEK
Kinase PEKa.AA Ciliate-E2 216-416 20 1.1e-29 99.08 In-house 109-365 (365) Show / Hide 
Range on Protein: 216-416
Range on HMM: 109-365/365
Sequence Identity: 20% (58 aa)

LYIQMEYCPR-TLRE-------------------VFDTRSVLDKELTWGI-------FRQIVEGLSHIHGQG-IIHRDLTPSNIFFDTRNDVKIGDFGLG
.|. ||||   .|..                   .   .. . |... |.       ...|...| ..| .. |||||. |.||.|     .|| |||| 
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGL-

VCAAKFADLQNPDQDHRVPVKFEANVKSLEGTGQVG----------------TYFYRAPEIEQ--------AWPHIDEKVDMYSLGVILFELW---HPFS
   .|..| .| .. |  .   .    . . ... |                |. | |||| .        .  . |.|.|..||||||.|.    .|| 
---SKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-

TGMERYVTLNELKQQNILPS-------------NW--AAKFPHQ-AALVHL----LVSPHPQDRPS-ARDVLQSELL
        ... ||..|  .             .|    | . .   |       .    |. |.. . ..|. . .
--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PEKa.AA GCN2 111-177 55 2.2e-29 99.83 In-house 1-72 (511) Show / Hide 
Range on Protein: 111-177
Range on HMM: 1-72/511
Sequence Identity: 55% (40 aa)

FEELCLLGKGGFGHVVL-CKNKLDGRRYAMKKVKLK-DENPSDK---ILREVATLSRLQHQHVVRYYQAWFE
|||.|.||||||| ||   .|..||| || || ... ..    .   |.|||..|.||.||||||||||| |
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRLHHQHVVRYYQAWIE
Kinase PEKa.AA STE-Unique 216-416 24 6.5e-29 99.49 In-house 369-616 (616) Show / Hide 
Range on Protein: 216-416
Range on HMM: 369-616/616
Sequence Identity: 24% (60 aa)

LYIQMEYCPR-TLREVFDTRSV---------LDKELTWGIFRQIVEGLSHIHGQG--IIHRDLTPSNIFFDTRN-----DVKIGDFGLGVCAAKF-----
..|.||||.  ||..  .  .          .  ..   . .||.||| ..| |.  |||||| |.|||..         |||.|||...| .       
VWIFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKD

ADLQNPDQDHRVPVK------------FEANVKSLEGTGQVGTYFYRAPEIEQAW----PHIDEKVDMYSLGVILFELWHPFSTGMERYVTLN----ELK
  ..|      .               .. |   . ... .|| .| .||.         ..| |||..||| ..|..   . . ..||. .      ..
NNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIH

QQNILP----SNWAAKF-PHQAALVHLLVSPHPQDRPSARDVLQSELL
.  ..|     | . |. | |. .  .. .. | .|||| . |....|
IHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase PEKa.AA PEK 319-416 34 1.1e-28 91.93 In-house 646-758 (758) Show / Hide 
Range on Protein: 319-416
Range on HMM: 646-758/758
Sequence Identity: 34% (39 aa)

TGQVGTYFYRAPE---------------IEQAWPHIDEKVDMYSLGVILFELWHP-FSTGMERYVTLNELKQQNILPSNWAAKFPHQAALVHLLVSPHPQ
|.||||  |..||                ||   . ..||| |||| |.||| || ||| |||  |.  |. . ..|. .. | | .. .. .. |. | 
TVQVGTHLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELIHPGFSTQMERIRTMCDLRNG-QWPKWFTQKYPQEYEFIQQMMSMNPD

DRPSARDVLQSELL
 ||.| ... . . 
ERPTADQISMHDFF
Kinase PEKa.AA PEK 111-178 41 6.6e-24 75.68 In-house 1-77 (758) Show / Hide 
Range on Protein: 111-178
Range on HMM: 1-77/758
Sequence Identity: 41% (32 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKD---------ENPSDKILREVATLSRLQHQHVVRYYQAWFET
||.   ||.|||| | . |||.|. .|| |.. ...         | . .| .||| ||  | |   |||. || ||
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLDHHNIVRYFNAWLET
Kinase PEKa.AA HRI 111-177 46 5.4e-23 77.43 In-house 1-69 (613) Show / Hide 
Range on Protein: 111-177
Range on HMM: 1-69/613
Sequence Identity: 46% (32 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPSD--KILREVATLSRLQHQHVVRYYQAWFE
||..  .||||.| |   ..|||.  || ||.| |     .  |..||| .|  |||  .||| |||.|
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQHHNIVRYHQAWIE
Kinase PEKa.AA STE-Unique 112-177 31 3.8e-20 67.79 In-house 1-72 (616) Show / Hide 
Range on Protein: 112-177
Range on HMM: 1-72/616
Sequence Identity: 31% (23 aa)

EELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPS------DKILREVATLSRLQHQHVVRYYQAWFE
..   .|.|.|| |..|.|| |..|.| |...||   ..       .|..|. ....| || .|.||..|..
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLW
Kinase PEKa.AA PEK 216-286 34 4e-19 59.4 In-house 414-512 (758) Show / Hide 
Range on Protein: 216-286
Range on HMM: 414-512/758
Sequence Identity: 34% (34 aa)

LYIQMEYC-PRTLREVFDTR---SVLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRND------------------------VKIGDFGL
.||||..|   ||.    .|   .  ....   .| ||.||.  ||. |.||||| ||||||    .                        .|||||||
MYIQMQLCRKETLKDWMRNRCTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQIIKIGDFGL
Kinase PEKa.AA PEK-Unclassified 317-414 33 1.7e-18 60.63 In-house 729-835 (835) Show / Hide 
Range on Protein: 317-414
Range on HMM: 729-835/835
Sequence Identity: 33% (36 aa)

EGTGQVGTYFYRAPEIE-----------QAWPHIDEKVDMYSLGVILFELWHPFSTGMERYVTLNELKQQNILPSNWAAKFPHQAALVHLLVSPHPQDRP
| |  .||| |  .| |           ||    . . |.||.|.|.|.. |.. | |||  |.  .|.   ||  . ||||  | ..   .|  || ||
EITSTCGTYTYSSNEQESQKKVRIKAHFQA-DFYNHRTDIYSVGIIFFQMFHQMNTTMERVKTIQNCKKGE-LPKHFCAKFPRLAEIIKDSLSNDPQKRP

SARDVLQSE
    . |  
LLSKIEQTL
Kinase PEKa.AA NEK 111-177 28 8.3e-18 59.61 In-house 1-75 (286) Show / Hide 
Range on Protein: 111-177
Range on HMM: 1-75/286
Sequence Identity: 28% (21 aa)

FEELCLLGKGGFGHVVLCKNKLDGRR-----YAMKKVKLKDENP--SDKIL-REVATLSRLQHQHVVRYYQAWFE
.|..  .|.| || | ... | ||.      |..||....  ..   .. .  ||  |..|.|...|.|| ...|
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIE
Kinase PEKa.AA NEK 213-286 31 4.1e-17 57.14 In-house 78-169 (286) Show / Hide 
Range on Protein: 213-286
Range on HMM: 78-169/286
Sequence Identity: 31% (29 aa)

STFLYIQMEYCPR--TLREVFDT---RS----VLDKELTWGIFRQIVEGLSHIHGQ-----GIIHRDLTPSNIFFDTRND----VKIGDFGL
. .|.| |||| .  .| . . .   .      .. |  | .| |.. .| ..| .      |.|||. |.||| . .|     |||||||.
NNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGI
Kinase PEKa.AA PEK-Unclassified 231-305 39 4.5e-16 51.87 In-house 604-682 (835) Show / Hide 
Range on Protein: 231-305
Range on HMM: 604-682/835
Sequence Identity: 39% (33 aa)

FDTRSVLDKELTWGIFRQIVEGLSHIHGQG-IIHRDLTPSNIFFDTRN--DVKIGDFGLGVCAAKFADLQNPDQ-----DHRV
||    ..|     | |||. .| ||| |. ..|||..| |||  . |   .|||||||   . |   | |. |     || .
FDILIFEYKQQCREITRQIIKALYHIHHQCKMVHRDIKPHNIFV-CQNPMQIKIGDFGL---VKKIEKLINDNQKIQYNDHQL
Kinase PEKa.AA PEK-Unclassified 111-177 28 1.1e-15 50.47 In-house 1-74 (835) Show / Hide 
Range on Protein: 111-177
Range on HMM: 1-74/835
Sequence Identity: 28% (21 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLK--------DENPSDKILREVATLSRLQHQHVVRYYQAWFE
| ..  .|.|||. |  | .|.|   || |.....           . .| ..||  . .. |  ..|||  | |
FNQVQKIGQGGFAIVYQCCHKFDQMEYAVKQIHVNIKDIKEDLQKHY-EKEIMEVRYMAQVNHPNIIRYYHSWIE
Kinase PEKa.AA Ciliate-E2 111-172 18 6.2e-11 33.75 In-house 1-98 (365) Show / Hide 
Range on Protein: 111-172
Range on HMM: 1-98/365
Sequence Identity: 18% (18 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYA--------------------------MKKVKLKDENPSDKILREVA----------TLSRLQHQHVVRYY
.. . ..|.|.|| | .||........|                          ||| ...  .  ..|.||.            |..|.| .....|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY
Kinase PEKa.AA TyrKc 111-416 16 3.1e-09 -73.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 111-416
Range on HMM: 1-280/280
Sequence Identity: 16% (59 aa)

FEELCLLGKGGFGHVVLCKNKLDGRRYAMKKVKLKDENPSDKILREVATLSRL--QHQHVVRYYQAWFET----------------AAGGS------SGT
 . .  || | || |.... |   .  | |..|         ..||   ...|  .|...|| | .  .                 ...|.      .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

PYGEESEISSSWVDTAGSSSNDVNTVSTFLYIQMEYCPRTLREVFDTRSVLDKELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRNDVKIGDFGL
|                                                 |  .    .  || .| ...| ...|||||   |.  . .. |||.||||
PK------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL

GVCAAKFA----------DLQNPDQ--DHR--VPVKFEANVKSLEGTGQVGTYFYRAPEIEQAWPHIDEKVDMYSLGVILFELW---HPFSTG-----ME
    ...           |   . .  . .  .|..                    |||         .| | .| || ..|.     .   |     |.
----SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR------------------WMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMS

RYVTLNELKQQNILPSNWAAKFPH---------QAALVHLLVS---PHPQDRPSARDVLQSELL
 .  .. .|| . .|     . |.          ...  .  .     | |||. ...   |..
NQEVIEYVKQGYRMP-----QPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PEKa.AA Pkinase_Tyr 111-172 24 9e-06 20.14 Pfam 1-70 (270) Show / Hide 
Range on Protein: 111-172
Range on HMM: 1-70/270
Sequence Identity: 24% (17 aa)

FEELCLLGKGGFGHVVLCKNK----LDGRRYAMKKVKLKDENP---SDKILREVATLSRL-QHQHVVRYY
 . .  ||.| ||.|.... |     ..   | |..| .   .   ... .||..... | .|...||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase PEKa.AA PKR 319-414 30 1.2e-05 16.0 In-house 181-272 (272) Show / Hide 
Range on Protein: 319-414
Range on HMM: 181-272/272
Sequence Identity: 30% (29 aa)

TGQVGTYFYRAPEIEQAWPHIDEKVDMYSLGVILFELWHPFSTGMERYVTLNELKQQNILPSNWAAKFPHQAALVHLLVSPHPQDRPSARDVLQSE
| . ||  | .||      |    ||.| ||.|| || |   | .|.    ..|..  .    .  |     .|.. |.|  |.|||   ..|.  
TRRKGTLQYMSPE-QIFSQHYGKEVDIYALGLILAELLHVCFTEFEKIKFFEDLRDGDFSNDIFDNK---EKTLLQKLLSKKPKDRPNTSEILRTL
Kinase PEKa.AA NEK 392-416 24 0.000213 11.85 In-house 262-286 (286) Show / Hide 
Range on Protein: 392-416
Range on HMM: 262-286/286
Sequence Identity: 24% (6 aa)

LVHLLVSPHPQDRPSARDVLQSELL
|....  . |..|||....|.  ..
LISQMLQKDPEQRPSCNQILEMPFI
Kinase PEKa.AA Pkinase_Tyr 247-286 42 0.001636 12.52 Pfam 118-157 (270) Show / Hide 
Range on Protein: 247-286
Range on HMM: 118-157/270
Sequence Identity: 42% (17 aa)

RQIVEGLSHIHGQGIIHRDLTPSNIFFDTRNDVKIGDFGL
.|| .|... . ...|||||   |.  .  | |||.||||
WQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase PEKa.AA HRI 215-229 40 0.125874 0.41 In-house 393-407 (613) Show / Hide 
Range on Protein: 215-229
Range on HMM: 393-407/613
Sequence Identity: 40% (6 aa)

FLYIQMEYCPRTLRE
.|.|||. |  .|..
MLHIQMQLCELSLWD
Kinase PEKa.AA CAMK 392-416 16 0.143921 0.01 In-house 401-425 (425) Show / Hide 
Range on Protein: 392-416
Range on HMM: 401-425/425
Sequence Identity: 16% (4 aa)

LVHLLVSPHPQDRPSARDVLQSELL
|.  .  . |..|... ..|. . .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PEKa.AA NEK 340-355 43 0.203641 1.23 In-house 202-217 (286) Show / Hide 
Range on Protein: 340-355
Range on HMM: 202-217/286
Sequence Identity: 43% (7 aa)

DEKVDMYSLGVILFEL
..|.|. |||..|.|.
NNKSDIWSLGCVLYEM
Kinase PEKa.AA Pkinase 401-416 37 0.401907 5.05 Pfam 278-293 (293) Show / Hide 
Range on Protein: 401-416
Range on HMM: 278-293/293
Sequence Identity: 37% (6 aa)

PQDRPSARDVLQSELL
|..||.|...||.. .
PKKRPTAEQILQHPWF