PEK_d

Species: S.moellendorffii
Alias: PEK_d
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PEK

Sequence

Name Sequence Type Origin Length Description Download
PEK_d.AA Protein None 833 None Fasta, JSON
PEK_d.NA RNA None 2502 None Fasta, JSON
PEK_d.kin_dom Protein Kinase Domain None 89 None Fasta, JSON

Protein domain

Protein domains of PEK_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PEK_d.AA PEK 253-324 36 2.9e-20 63.27 In-house 686-758 (758) Show / Hide
Range on Protein: 253-324
Range on HMM: 686-758/758
Sequence Identity: 36% (27 aa)

DVYSLGVLFFELFCV-FSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF
| ||||  ||||.   ||  ||  | | |||  ..|...... |.|. . .......|  || | .|    .|
DIYSLGLIFFELIHPGFSTQMERIRTMCDLRNGQWPKWFTQKYPQEYEFIQQMMSMNPDERPTADQISMHDFF

Kinase PEK_d.AA PEK 252-324 35 1.4e-19 64.22 In-house 575-655 (655) Show / Hide
Range on Protein: 252-324
Range on HMM: 575-655/655
Sequence Identity: 35% (29 aa)

SDVYSLGVLFFELFCVFSSNM-EWSRAMSDLRH------RILP-PRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF
.|.||||..|||..  |.. | | .. . |||        ..| ... .. ||.| . .|.|.. || || | .| | |.|
VDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF

Kinase PEK_d.AA HRI 237-324 36 7.6e-12 37.26 In-house 526-613 (613) Show / Hide
Range on Protein: 237-324
Range on HMM: 526-613/613
Sequence Identity: 36% (32 aa)

YTSPEELAGGASSFASDVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCELF
| ||| | |      || ||.||  ||||  |   ||    .  .|   .|  |    |  |     |       || |  . | |||
YASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTEMERAEVLTGVRTGQIPESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF

Kinase PEK_d.AA GCN2 253-324 29 9.8e-11 33.39 In-house 434-511 (511) Show / Hide
Range on Protein: 253-324
Range on HMM: 434-511/511
Sequence Identity: 29% (23 aa)

DVYSL-GVLFFELFCV-FSSNMEWSRAMSDLRHRILPPRLLS----ESPKEAALCLWLLHPEPQSRPKAREIFQCELF
|.||| |..|||..   |.. || .    .||   .|. . .    ...... .  |.| . ||.||.|... | |. 
DMYSLGGIIFFEMWYPPFCTQMERVQILKQLRSCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL

Kinase PEK_d.AA PEK-Unclassified 253-322 28 3.2e-08 23.65 In-house 766-835 (835) Show / Hide
Range on Protein: 253-322
Range on HMM: 766-835/835
Sequence Identity: 28% (20 aa)

DVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCE
|.||.|. ||..|  .   || .. .. ..   ||       |. | .    |  .|| ||    | |  
DIYSVGIIFFQMFHQMNTTMERVKTIQNCKKGELPKHFCAKFPRLAEIIKDSLSNDPQKRPLLSKIEQTL

Kinase PEK_d.AA RTKL 239-263 48 1e-06 13.19 In-house 174-198 (259) Show / Hide
Range on Protein: 239-263
Range on HMM: 174-198/259
Sequence Identity: 48% (12 aa)

SPEELAGGASSFASDVYSLGVLFFE
||| | |..   ||||   ||. .|
SPETLNGKPHTMASDVWAFGVVCYE

Kinase PEK_d.AA Pkinase 236-324 19 2e-06 24.14 Pfam 176-293 (293) Show / Hide
Range on Protein: 236-324
Range on HMM: 176-293/293
Sequence Identity: 19% (24 aa)

WYTSPEELA-GGASSFASDVYSLGVLFFELFCVFSSNMEWSRA-------MSDLRHRILPPRLLSESPKE------------------------AALCLW
|| .|| .  |   . ..|..|.|....|..|    .  .. .       .  .  ||..|.| ...|..                          .. |
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC---GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

LLHPEPQSRPKAREIFQCELF
.|.. |..|| |..|.| . |
CLCKDPKKRPTAEQILQHPWF

Kinase PEK_d.AA urchC 237-261 44 2e-06 16.61 In-house 197-223 (223) Show / Hide
Range on Protein: 237-261
Range on HMM: 197-223/223
Sequence Identity: 44% (12 aa)

YTSPEELA--GGASSFASDVYSLGVLF
.. || |   | . | |||.|| ||. 
HIAPEVLDIDGCQVSVASDIYSVGVIL

Kinase PEK_d.AA Ciliate-E2 237-266 28 7e-06 16.24 In-house 253-291 (365) Show / Hide
Range on Protein: 237-266
Range on HMM: 253-291/365
Sequence Identity: 28% (11 aa)

YTSPEELAGGA---------SSFASDVYSLGVLFFELFC
| .|| | |.           ....|..||||...|. .
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

S_TKc PEK_d.AA S_TKc 2-324 10 9e-06 -91.92 SMART 1-231 (231) Show / Hide
Range on Protein: 2-324
Range on HMM: 1-231/231
Sequence Identity: 10% (37 aa)

KRKSTELGD-------AGIDLERRRDSSDNATTAASVFAQGPRSGSQSRVAASSSSVENRLPPASMELVLATDAGDGDTNMNDTGAEEEEEEDDGGN---
 ..  ..|         ... .      ..   |  .                          .  |. .           |     .  ..   ..   
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK----------------------EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYM

--DHVGD--VTLRQWLRPGRT------VDRVACLHIFKQVLEFVELAQKQGVILRTIRPSCFMISPLHRI--------TFIESASSSDRSSEHSTGRAAD
  ....    .|.. ..  ..       .   . ....|... .|   ..|.| | . |.  ...   .|        ...                   
VMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------

FPEQDMGMEAQRNVDAAAITDLQRALAQPDDQWTSSFDPSEPSSHEIDENFPLRQVLAKEQT-----WYTSPEELAGGASSFASDVYSLGVLFFELFC--
                                                             |     || .|| |  | . ...|..|.|....|..|  
------------------------------------------------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGY

-VFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQ-------CELF
  |.        |  . ..|.       ||    .   .|. .|. || | |..|        . |
PPFP-------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PEK_d.AA TKL 237-322 16 1.4e-05 16.12 In-house 239-364 (364) Show / Hide
Range on Protein: 237-322
Range on HMM: 239-364/364
Sequence Identity: 16% (21 aa)

YTSPEELAGG----------------ASSFASDVYSLGVLFFELFC---VFSSNMEWSRA---------MSDLRHRILPPRL------------LSESPK
. .|| | |                   | ..|||| |....|...   ... ... ..          | .  ..  ||.              .  | 
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS

EAALCLWLLHPEPQSRPKAREIFQCE
 . |. .  ...|..|| . || .  
MKKLMQDCWDHDPEKRPSFQEILKRL

Kinase PEK_d.AA PKR 237-322 29 2.7e-05 14.75 In-house 189-272 (272) Show / Hide
Range on Protein: 237-322
Range on HMM: 189-272/272
Sequence Identity: 29% (25 aa)

YTSPEELAGGASSFASDVYSLGVLFFELFCVFSSNMEWSRAMSDLRHRILPPRLLSESPKEAALCLWLLHPEPQSRPKAREIFQCE
| ||| .         |.| ||..  ||  |   ..| ..   |||. ..   .  .  || .|   ||   |. ||.  || .  
YMSPEQIFSQHYGKEVDIYALGLILAELLHVCFTEFEKIKFFEDLRDGDFSNDIFDN--KEKTLLQKLLSKKPKDRPNTSEILRTL

Kinase PEK_d.AA PEK 98-126 31 0.004671 4.68 In-house 425-456 (758) Show / Hide
Range on Protein: 98-126
Range on HMM: 425-456/758
Sequence Identity: 31% (10 aa)

TLRQWLRPG---RTVDRVACLHIFKQVLEFVE
||..|.|     . ...  .||.|.| .| |.
TLKDWMRNRCTMESRPWMHMLHWFHQICEGVN

Kinase PEK_d.AA PKR 98-141 32 0.006562 6.1 In-house 107-152 (272) Show / Hide
Range on Protein: 98-141
Range on HMM: 107-152/272
Sequence Identity: 32% (15 aa)

TLRQWL--RPGRTVDRVACLHIFKQVLEFVELAQKQGVILRTIRPS
|| ||.  | .  ||.|  | .. |. . |.    ...| | ..||
TLEQWMRNRRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPS

Kinase PEK_d.AA PEK 98-123 15 0.146224 0.32 In-house 369-438 (655) Show / Hide
Range on Protein: 98-123
Range on HMM: 369-438/655
Sequence Identity: 15% (11 aa)

TLRQWLRPGR--------------------------------------------TVDRVACLHIFKQVLE
|||.|.. ..                                             .|.. |..||.|.||
TLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILE

Kinase PEK_d.AA Ciliate-E2 304-324 22 0.208529 0.57 In-house 344-365 (365) Show / Hide
Range on Protein: 304-324
Range on HMM: 344-365/365
Sequence Identity: 22% (5 aa)

LLHPEPQSRPK-AREIFQCELF
.|  .|. |.  . .|.. . |
MLQKDPEKRITGWEQILNHPWF

WD40 PEK_d.AA WD40 504-548 11 0.00161 17.99 SMART 1-46 (46) Show / Hide
Range on Protein: 504-548
Range on HMM: 1-46/46
Sequence Identity: 11% (6 aa)

RFEVKATLR-HGDLLNTANMVCSLSFDRDE------EFFATAGVCKKIKVFE
  .. .|.. | .       |...... |       ...|...  ..|....
T-KCVHTFKGHTGN----SWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 523-548 14 0.017036 9.8 Pfam 13-39 (39) Show / Hide
Range on Protein: 523-548
Range on HMM: 13-39/39
Sequence Identity: 14% (4 aa)

VCSLSFDRD-EEFFATAGVCKKIKVFE
|...... |   ..|...  ..|....
VTCCAWHPDMGHYLASGSRDGTIRIWD

WD40 PEK_d.AA WD40 559-598 22 0.007787 13.67 SMART 1-46 (46) Show / Hide
Range on Protein: 559-598
Range on HMM: 1-46/46
Sequence Identity: 22% (11 aa)

IHYPVVEMA-SRS--KLSNICWNSYI-----KSHLASSDYDGVIQLWD
   .| ..   ..    . .||..       ...|||.. || | .||
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 575-598 37 0.009966 10.47 Pfam 16-39 (39) Show / Hide
Range on Protein: 575-598
Range on HMM: 16-39/39
Sequence Identity: 37% (9 aa)

ICWNSYIKSHLASSDYDGVIQLWD
..|.    ..|||.  || | .||
CAWHPDMGHYLASGSRDGTIRIWD

WD40 PEK_d.AA WD40 602-641 25 8.8e-13 39.4 Pfam 1-39 (39) Show / Hide
Range on Protein: 602-641
Range on HMM: 1-39/39
Sequence Identity: 25% (10 aa)

SQTLVEYKEHEKRAWSVDFSHADPTKLASGSDDGTVKLWS
.. . .. .|..  ....... ... |||||.|||...|.
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD

WD40 PEK_d.AA WD40 601-641 29 8.6e-11 43.09 SMART 1-46 (46) Show / Hide
Range on Protein: 601-641
Range on HMM: 1-46/46
Sequence Identity: 29% (14 aa)

TSQTLVEYKEHEK--RAWSVDFSHAD-----PTKLASGSDDGTVKLWS
| . . ..| |..  . ..|.... .     |. ||||| |||...|.
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 644-683 25 0.007787 13.67 SMART 1-46 (46) Show / Hide
Range on Protein: 644-683
Range on HMM: 1-46/46
Sequence Identity: 25% (12 aa)

QEASTGTIK-TKA--NVCCVQFPSDS-----AHLLTFGSADYKIYCYD
.   . |.|  ..   |.||.. .|.      ..|  || | .|...|
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 657-683 37 0.562315 5.43 Pfam 13-39 (39) Show / Hide
Range on Protein: 657-683
Range on HMM: 13-39/39
Sequence Identity: 37% (10 aa)

VCCVQFPSDSAHLLTFGSADYKIYCYD
|.|. .  |. |.|  ||.| .|  .|
VTCCAWHPDMGHYLASGSRDGTIRIWD

WD40 PEK_d.AA WD40 688-725 20 4.1e-10 31.71 Pfam 1-39 (39) Show / Hide
Range on Protein: 688-725
Range on HMM: 1-39/39
Sequence Identity: 20% (8 aa)

KGPLCILSSHNKAVSYVRFVDS--STIVSASTDSTLKLWD
. .. ..  |...|. ......  . ..|.| |.|...||
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD

WD40 PEK_d.AA WD40 687-725 20 1.3e-08 35.88 SMART 1-46 (46) Show / Hide
Range on Protein: 687-725
Range on HMM: 1-46/46
Sequence Identity: 20% (10 aa)

TKGPLCILSSHNK--AVSYVRFVDS-------STIVSASTDSTLKLWD
|  ...... |..  .|. |.. ..       . ..|.| |.|...||
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 736-775 20 0.017375 11.47 SMART 1-46 (46) Show / Hide
Range on Protein: 736-775
Range on HMM: 1-46/46
Sequence Identity: 20% (10 aa)

SNACSLTYTGHTN--EKNFVGLSVSD------GYIACGSETNAVFCYH
.  |  |..|||.  . . |  . ..       |.|.||  . . ...
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD

WD40 PEK_d.AA WD40 737-775 22 0.614052 5.32 Pfam 1-39 (39) Show / Hide
Range on Protein: 737-775
Range on HMM: 1-39/39
Sequence Identity: 22% (9 aa)

NACSLTYTGHTNEKNFVGLSVS-DGYIACGSETNAVFCYH
  |  |. |||.  . .  . .   |.|.||. . .  . 
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD