Gene ULK_b (S.moellendorffii)

ULK_b

Species: S.moellendorffii
Alias: ULK_b
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK_b.AA Protein None 452 None Fasta, JSON
ULK_b.NA RNA None 1359 None Fasta, JSON
ULK_b.kin_dom Protein Kinase Domain None 191 None Fasta, JSON

Protein domain

Protein domains of ULK_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ULK_b.AA AGC 115-197 23 7.9e-33 80.92 In-house 277-395 (395) Show / Hide 
Range on Protein: 115-197
Range on HMM: 277-395/395
Sequence Identity: 23% (28 aa)

EAIVYDAKADLWS--VGVMLYQMITGRRPFEACSSE----------DLFRKLG-------NKIQFR--------GEDYWDPDCRDLCEGLLRKNPLERIS
| . |.  .| ||  .|...|.|.||. || . . .          ..| |         .|..|         ......|...||...|| |.| .|. 
EIL-YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLG

----------FEEFFNHKFL
          .||  ||.. 
CGGNDFGDKGAEEIKNHPWF
Kinase ULK_b.AA ULK 1-107 31 5.9e-31 107.11 In-house 41-164 (324) Show / Hide 
Range on Protein: 1-107
Range on HMM: 41-164/324
Sequence Identity: 31% (40 aa)

MDQFRQQ------LELIAQEQAIMKSIA---HPN--VVKLLGMISEDEHDELSTKYLVMEFCEGGDLDHYIHLNKKVSAGV----------ARTIMLQLA
| .. ..      ..|. .|  ||| .    |||  .|||. .  .. |      |..||.|.||||..||. ||| .  .          |. .. |..
MNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH---NNIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQIC

AALQELRRMNLIHRDLKPHNLLLKNKVA
....||. .| ||||.|| |.|..|...
NGFKELHKHNIIHRDIKPQNILIHNGQP
Kinase ULK_b.AA ULK 6-107 33 1.6e-28 96.71 In-house 52-168 (329) Show / Hide 
Range on Protein: 6-107
Range on HMM: 52-168/329
Sequence Identity: 33% (40 aa)

QQLELIAQEQAIMKSIA--------HPNVVKLLGMISEDEHDELSTKYLVMEFCEGGDLDHYIHLNKK----------VSAGVARTIMLQLAAALQELRR
....|. .|  ||| .         |||.|||. .  .. |      |..||.|.||||..||. |||           |   |. .. |......||. 
YMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH---NNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK

MNLIHRDLKPHNLLLKNKVA
.| ||||.|| | |..|...
HNIIHRDIKPQNILIHNGQP
Kinase ULK_b.AA S_TKc 2-197 23 1.8e-27 98.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-197
Range on HMM: 1-231/231
Sequence Identity: 23% (61 aa)

DQFRQQL--------------------------ELIAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTKYLVMEFCEG--GDLDHYIHLNKK------VS
 .. ...                          | | .| .|.|.  |||.|||.... .      .  |.|||.|.|  ||| .||. ...       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

AGVARTIMLQLAAALQELRRMNLIHRDLKPHNLLLKNKVAPGSDPEGEAIV---------------------------YDA-KADLWSVGVMLYQMITGR
  .|| .| |.. ||. . ... ||||||| |.|| .             .                           |.  |.| ||.|..|| |..|.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGY

RPFEACSSEDLFRKLGNKIQFRGEDYWDPDCRDLCEGLLRKNPLERISFEEFFN-------HKFL
 ||.    . .|.|.|           .|...|. ...|.|.| .|..  | ..       | ..
PPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK_b.AA ULK 119-197 30 9.5e-26 86.92 In-house 233-329 (329) Show / Hide 
Range on Protein: 119-197
Range on HMM: 233-329/329
Sequence Identity: 30% (30 aa)

YDAKADLWSVGVMLYQMITGRRPFEACSSEDLF-----RKLGNK-----------IQFR---GEDYWDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
||.|.|.||.|...|.|..|. ||.|.  .|..     . . |.           .||.    ..   |.|.||  ..| ... .|||.||.|||...
YDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK_b.AA ULK 119-197 30 3.1e-25 86.51 In-house 228-324 (324) Show / Hide 
Range on Protein: 119-197
Range on HMM: 228-324/324
Sequence Identity: 30% (30 aa)

YD-AKADLWSVGVMLYQMITGRRPFEACSSEDLF----RKLGN-----------KIQFRG--EDYW-DPDCRDLCEGLLRKNPLERISFEEFFNHKFL
|. .|.|.||.|...|.|..|. ||...  .|..    . . |           .|||.   .|.   |.|.||  ..| ... .|||.||.|||...
YYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK_b.AA CAMK 6-105 24 1.6e-24 75.31 In-house 73-215 (425) Show / Hide 
Range on Protein: 6-105
Range on HMM: 73-215/425
Sequence Identity: 24% (35 aa)

QQLELIAQEQAIMKSIA-------HPNVVKLLGMISEDEH-------DELST--------KYLVM---EFCEGG----DLDHYIHLN-------------
. .. . .| .|||..        |||..||. ..  ...       .  |.         |.||   |.|.||    ||  ||  .             
KDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV

--KKVSAGVARTIMLQLAAALQELRRMNLIHRDLKPHNLLLKNK
  ....   ||... |.. |.. .  .| .|||||| |.|| ..
ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDN
Kinase ULK_b.AA Ciliate-E2 119-197 28 4.4e-24 79.56 In-house 273-365 (365) Show / Hide 
Range on Protein: 119-197
Range on HMM: 273-365/365
Sequence Identity: 28% (29 aa)

YDAKADLWSVGVMLYQMITGRRPFEACSSEDLFRKLGNKIQFRGE----------------DYWDPDCRDLCEG----LLRKNPLERIS-FEEFFNHKFL
|| |.|.||.||.||.|..|..||       .  .. .||.|. .                ..|...| ||.      .| |.| .||. .|. .||...
YDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK_b.AA CAMKL 1-102 30 5.4e-23 70.08 In-house 40-160 (297) Show / Hide 
Range on Protein: 1-102
Range on HMM: 40-160/297
Sequence Identity: 30% (37 aa)

MDQFRQQLEL---------IAQEQAIMKSIA---HPNVVKLLGMISEDEH--DELSTKYLVMEFCEGGD--LDHYIHLN----KKVSAGVARTIMLQLAA
.|.. ..  .         | .| .|||..    |||..||. .|  .||  .  .  ||||| |.||.  | .||  .    .. . . || .  |. .
NDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVS

ALQELRRMNLIHRDLKPHNLLL
|.. . ... .|||.|| |.||
AVNYCHSHGIVHRDIKPENILL
Kinase ULK_b.AA Pkinase 2-105 33 2.6e-22 79.97 Pfam 39-144 (293) Show / Hide 
Range on Protein: 2-105
Range on HMM: 39-144/293
Sequence Identity: 33% (37 aa)

DQFRQQLELIAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTKYLVMEFCEGG----DLDHYIH--LNKKV--SAGVARTIMLQLAAALQELRRMNLIHR
....|.. .. .| .|||.. |||.|.|...  .  .|..    .|||.||||    || .||.   ....  |  ... .|.|.. .|. . .|. |||
SWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED--KDHIY---MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHR

DLKPHNLLLKNK
|||| |.|..|.
DLKPENILIDNN
Kinase ULK_b.AA Ciliate-E2-Unclassified 119-197 29 3.3e-22 73.85 In-house 243-352 (352) Show / Hide 
Range on Protein: 119-197
Range on HMM: 243-352/352
Sequence Identity: 29% (32 aa)

YD----AKADLWSVGVMLYQMITGRRPFEACSSED----------------LFRKL-GNKIQFRGEDY------WDPDCRDLCE----GLLRKNPLERIS
||     |.| ||.|| ||.|..|..||.. ..|.                |...   ..|||. ..       |.| . |...     .| ||| .||.
YDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRIT

FEEFFNHKFL
||. .|| ..
FEQILNHPWF
Kinase ULK_b.AA Ciliate-E2 11-102 31 3.2e-21 69.6 In-house 80-194 (365) Show / Hide 
Range on Protein: 11-102
Range on HMM: 80-194/365
Sequence Identity: 31% (38 aa)

IAQEQAIMKSIAHPNVVKLLGMISE-DEHDELSTKYLVMEFCEGGDLDHYIHLN-----------KKVSAGVARTIMLQLAA---------------ALQ
| .|. |.... |||..|.     | |..    . |||||.|.|||| .||  |           |. .   ...|| |..                ||.
I-NEKNILEQLNHPNIIKMYECFQEKDDN----NIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALE

ELRRMN-LIHRDLKPHNLLL
.|   |  ||||.|| |.|.
YLHSKNNIIHRDIKPENILF
Kinase ULK_b.AA Pkinase 119-197 21 3e-19 69.16 Pfam 189-293 (293) Show / Hide 
Range on Protein: 119-197
Range on HMM: 189-293/293
Sequence Identity: 21% (23 aa)

YDAKADLWSVGVMLYQMITGRRPFEAC----SSEDLFRKLGNKIQFRGEDYWD-----------------------PDCRDLCEGLLRKNPLERISFEEF
|. |.| ||.|..||.|..|| ||  .    .  |   .. .. . . .  |.                       ..|.|.....|.|.| .|...|. 
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

FNHKFL
..|...
LQHPWF
Kinase ULK_b.AA AGC 5-102 23 9.8e-19 43.63 In-house 49-188 (395) Show / Hide 
Range on Protein: 5-102
Range on HMM: 49-188/395
Sequence Identity: 23% (34 aa)

RQQLELIAQE------------QAIMKSIA----------HPNVVK-LLGMISEDEHDELSTKYLVMEFCE--------GGDLDHYIHLNK-----KVSA
....| .  |              |.. .           ||..|| |      ..|. |   |.|||...        ||... ..|| .     . . 
KNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHTYL---YFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDE

GVARTIMLQ-------LAAALQELRR-MNLIHRD-LKPHNLLL
 .|| .. .       .. ||. | . |. |||| ||| |.||
ERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILL
Kinase ULK_b.AA AMPK 11-102 31 9e-18 49.4 In-house 46-133 (254) Show / Hide 
Range on Protein: 11-102
Range on HMM: 46-133/254
Sequence Identity: 31% (30 aa)

IAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTK---YLVMEFCEGGDLDHYIHLNKKVSAGVARTIMLQLAAALQELRRMNLIHRDLKPHNLLL
|. |  |.|.. ||....|   |       ..|.   ..|||.  ||.|  ||  .....   |.  . |  ...  . | .  |||||| ||||
IQREIHILKLFRHPHIIQLYEVI-------IETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLL
Kinase ULK_b.AA STE 1-106 26 1.1e-17 59.09 In-house 65-186 (359) Show / Hide 
Range on Protein: 1-106
Range on HMM: 65-186/359
Sequence Identity: 26% (33 aa)

MDQFRQQLELIAQEQAIMKSIA--HPNVVKLLGMISEDE--HDELSTKYLVMEFCEGGDLDHYIHLNKKVS--------------AGVARTIMLQLAAA-
.. . .... | .|  |||     |||.|| .|.   .   |.. .. ...||...|| ||  |. ....                 . ..|  |.  . 
ENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGL

LQELRRMNLIHRDLKPHNLLLKNKV
|. | ... ||||.|| | ||   |
LYYLHSHHIIHRDIKPANILL---V
Kinase ULK_b.AA AMPK 124-197 31 4.1e-17 47.41 In-house 182-254 (254) Show / Hide 
Range on Protein: 124-197
Range on HMM: 182-254/254
Sequence Identity: 31% (23 aa)

DLWSVGVMLYQMITGRRPFEACSSEDLFRKLGNKIQFRGEDYWDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
|.|| || || |. |. ||.  .  .|..|  |   .   ..  |...|| ...|...|..||....  ||...
DIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGE-YYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase ULK_b.AA RSK 119-197 23 4.2e-17 59.33 In-house 189-278 (278) Show / Hide 
Range on Protein: 119-197
Range on HMM: 189-278/278
Sequence Identity: 23% (21 aa)

YDAKADLWSVGVMLYQMITGRRPFEA---CSSEDLFRKLGNKI-QFRGE--DYWDPDCRDLCEGLLRKNPLERIS-----FEEFFNHKFL
.|. .|.|| || .| | ||..|| .    ........ ...   ....  .|  ....||  ..| ..|  |..      ||  .|...
HDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase ULK_b.AA CAMK 119-197 26 4.9e-17 50.75 In-house 311-425 (425) Show / Hide 
Range on Protein: 119-197
Range on HMM: 311-425/425
Sequence Identity: 26% (30 aa)

YDAKADLWSVGVMLYQMITGRRPFEAC-------------SSEDLFRKLG-NKIQFR-----------GEDYWD-----------PDCRDLCEGLLRKNP
|. |.| ||.||.|| | .|. ||..              . ..||.|    | .|            |...||           ..|.||  ..|...|
YGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDP

LERISFEEFFNHKFL
 .|.. |.  ||...
EKRMTIEQCLNHPWM
Kinase ULK_b.AA Ciliate-E2-Unclassified 11-105 29 8.7e-17 54.77 In-house 70-180 (352) Show / Hide 
Range on Protein: 11-105
Range on HMM: 70-180/352
Sequence Identity: 29% (35 aa)

IAQEQAIMKSIAHPNVVKLLGMISEDEHDELSTKYLVMEFCEGGDLDHYIHLNKK-----------------VSAGVAR-----TIMLQLAAALQELRRM
|.|.  |.... ||..||.. .   ..     . |.|||.||||||  ||  .||                 ..   |.     ... |.  .|. | . 
IMQQ--ILLNHPHPFIVKMFYCFQDKQ-----NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHK

N-LIHRDLKPHNLLLKNK
|  ||||.|| |.|..|.
NNIIHRDIKPENILFDNN
Kinase ULK_b.AA CAMKL 122-197 27 6.7e-14 40.59 In-house 216-297 (297) Show / Hide 
Range on Protein: 122-197
Range on HMM: 216-297/297
Sequence Identity: 27% (23 aa)

KADLWSVGVMLYQMITGRRPFEACSS--------EDLFRKLGNKIQFRGEDYWDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
|.| || ||.|| |..|. ||.. .         . . .. .   ...   . . |||||  ..| .|| .|.. ..  ||...
KVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase ULK_b.AA Pkinase_Tyr 5-95 29 8.6e-14 47.34 Pfam 43-137 (270) Show / Hide 
Range on Protein: 5-95
Range on HMM: 43-137/270
Sequence Identity: 29% (29 aa)

RQ--QLELIAQEQAIMKSI-AHPNVVKLLGMIS-EDEHDELSTKYLVMEFCEGGDLDHYIHL----NKKVSAGVARTIMLQLAAALQELRRMNLIHRDL
.|  . .... | .|||..  |||.|.|.| .. ..|.      |.|||....|||..| .     .....      . .| |.... | ..|.|||||
EQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase ULK_b.AA STE 119-197 19 1.8e-13 44.07 In-house 245-359 (359) Show / Hide 
Range on Protein: 119-197
Range on HMM: 245-359/359
Sequence Identity: 19% (22 aa)

YDAKADLWSVGVMLYQMITGRRPFEACSSE-DLFRKL----------------GNKIQFRG-----------------EDYWDPDCRDLCEGLLRKNPLE
||.|.| ||.| ..  |.||. |.   .    .|...                |.  ..                    . | |...|  .  |.|.| .
YDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNK

RISFEEFFN--HKFL
| . ..  .  |.|.
RPTASQLLKSEHPFI
Kinase ULK_b.AA RSK 13-102 32 2.6e-11 37.96 In-house 49-137 (278) Show / Hide 
Range on Protein: 13-102
Range on HMM: 49-137/278
Sequence Identity: 32% (31 aa)

QEQAIMKSIA-HPNVVKLLGMISEDEHDELSTKYLVMEFCEGGDLDHYIHLNKKVSAG-----VARTIMLQLAAALQELRRMNLIHRDLKPHNLLL
.|. |.. .  ||..|.|      . ... .  ||.||.|.||.|  . || |... |      |. .| ... |.. |     ||||||| | |.
TERNILERCQQHPFIVTLH-----YAFQTEGKLYLIMEYCRGGEL--FTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILY
Kinase ULK_b.AA TyrKc 2-197 16 8.5e-11 -48.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-197
Range on HMM: 1-280/280
Sequence Identity: 16% (46 aa)

DQFRQQL---------------------------ELIAQEQAIMKSI--AHPNVVKLLGMISEDEHDEL---STKYLVMEFCEGGDLDHYIHLNKK-VSA
 .. ..|                           | . .|  ||...   |||.|.|.| .....          ..|||....|||..|.. ... .. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

GVARTIMLQLAAALQELRRMNLIHRDLKPHNLLLKNKV------------APGS----------------DPEG---------EAI---VYDAKADLWSV
     ...| |.  . | ..|.|||||   | |....                                 .  .         |.|   ..  | | || 
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSF

GVMLYQMIT-GRRPFEA-----CSSEDLFRKLGNKIQFRGEDY--------WDPDCRDLCEGLLRKNPLERISFEEFFNHKFL
||... . | |  | .      .| ....... .    .  ..          ..  .. .   . .| .| .|.|   |...
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF