Gene WEE-S1_f (S.moellendorffii)

WEE-S1_f

Species: S.moellendorffii
Alias: WEE-S1_f
External Links:
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
WEE-S1_f.AA Protein None 129 None Fasta, JSON
WEE-S1_f.NA RNA None 390 None Fasta, JSON
WEE-S1_f.kin_dom Protein Kinase Domain None 109 None Fasta, JSON

Protein domain

Protein domains of WEE-S1_f.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase WEE-S1_f.AA WEE 1-129 25 6.6e-29 94.15 In-house 10-180 (297) Show / Hide 
Range on Protein: 1-129
Range on HMM: 10-180/297
Sequence Identity: 25% (44 aa)

GNFSYVYKVLKRLDGCLYSVKHSNWHLLNEGD-QRKALREVQALLCLS------CHENVVHYFSLWFKNDFLYIQIELYES-----LAWT---------F
| |. |||. .|.|||.| .| |  . ...   .  |||||.|.  |.      .|...| |.| |  .| .||| |. ..     ..|          .
GSFGEVYKCRCRIDGCIYAIKKSK-QPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQCHNWNHWL

TEKKLIEVMFQLLNTFKHLHSH-GLTHLDVKLDKIYICNH---------------------VYKIGNLGLAS
.|...  .  ..... .|.||. |. |.|.| . |.|...                     ..||| .|...
PEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVT
Kinase WEE-S1_f.AA Pkinase 1-111 23 9e-13 46.24 Pfam 10-137 (293) Show / Hide 
Range on Protein: 1-111
Range on HMM: 10-137/293
Sequence Identity: 23% (30 aa)

GNFSYVYKVLKRLDGCLYSVKHSNWHLLNEGDQRKALR--EVQALLCLSCHENVVHYFSLWFKNDFLYIQIELY--E----SLA-----------WTFTE
|.|. |||  .. .|... ||  . .  ... .. ..|  |.| .. | .|.|.| ..  .  .| .|.  |.        .|.             |.|
GSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSE

KKLIEVMFQLLNTFKHLHSHGLTHLDVKLD
. .. .| |.|   ...||.|  | |.|..
WECKFYMYQILRGLEYCHSMGIIHRDLKPE
Kinase WEE-S1_f.AA ULK 78-128 32 1.1e-09 30.09 In-house 126-189 (329) Show / Hide 
Range on Protein: 78-128
Range on HMM: 126-189/329
Sequence Identity: 32% (21 aa)

TFTEKKLIEVMFQLLNTFKHLHSHGLTHLDVKLDKIYICNH-------------VYKIGNLGLA
...|.. |... |.|| ||.||.|.  | | |.. | | |.             |.||.  |.|
RLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase WEE-S1_f.AA ULK 78-128 31 1.3e-09 30.37 In-house 122-185 (324) Show / Hide 
Range on Protein: 78-128
Range on HMM: 122-185/324
Sequence Identity: 31% (20 aa)

TFTEKKLIEVMFQLLNTFKHLHSHGLTHLDVKLDKIYICNH-------------VYKIGNLGLA
...|.. |... |..| ||.||.|.  | | |.. | | |.             |.||.  |.|
RLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase WEE-S1_f.AA PEK 1-63 30 5.4e-09 26.68 In-house 10-87 (655) Show / Hide 
Range on Protein: 1-63
Range on HMM: 10-87/655
Sequence Identity: 30% (25 aa)

GNF-SYVYKVLKRLDGCLYSVKHSNWHLLNEGDQ-----------------RKALREVQALLCLSCHENVVHYFSLWFKND
| |   ||||  .||||.| .|   ..| . ...                 .|.||||..| .|. |.|.|.|.. |. ..
GGFGGQVYKVQNKLDGCYYAIK--RIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLN-HPNIVRYHNAWIEKP
Kinase WEE-S1_f.AA MOK 1-126 30 9.4e-09 23.03 In-house 10-144 (283) Show / Hide 
Range on Protein: 1-126
Range on HMM: 10-144/283
Sequence Identity: 30% (42 aa)

GNFSYVYKVLKRLDGCLYSVKHSNWHLLNEGDQRKALREVQALLCLSCHENVVHYFSLWF--KNDFLYIQIEL-----YESL---AWTFTEKKLIEVMFQ
| || | |.    ||  |. |    | ..  .|  .|||.||.  |. | |...     |  |   | .  ||     || .    .   .||. . |.|
GTFSEVMKMQSLRDGNYYACKQMKQH-FESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQKKIMHYMYQ

LLNTFKHLHSHGLTHLDVKLDKIYICNHVYKIGNLG
|. .  |.|  |. | ||| . | | . . |..  |
LCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFG
Kinase WEE-S1_f.AA STE 29-109 23 5.5e-08 24.42 In-house 68-179 (359) Show / Hide 
Range on Protein: 29-109
Range on HMM: 68-179/359
Sequence Identity: 23% (26 aa)

NEGDQRKALREVQALLCLSC-HENVVHYFSLWFKN-------DFLYIQIELYE--SLA--------------------WTFTEKKLIEVMFQLLNT-FKH
|. .. . |.|.. . .... |.|.|.|.   ||.       | |.|  |. .  ||                     ..| |. .. . .|.|    ..
NHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYY

LHSHGLTHLDVK
||||.  | |.|
LHSHHIIHRDIK
Kinase WEE-S1_f.AA Ciliate-B2 79-109 32 5.6e-08 14.74 In-house 101-131 (197) Show / Hide 
Range on Protein: 79-109
Range on HMM: 101-131/197
Sequence Identity: 32% (10 aa)

FTEKKLIEVMFQLLNTFKHLHSHGLTHLDVK
|...||. ..|||..    ...   .|||.|
FNNQKLYQMIFQLIDGLIQFRMYNILHLDIK
Kinase WEE-S1_f.AA CAMK 1-128 12 4e-06 15.1 In-house 5-243 (425) Show / Hide 
Range on Protein: 1-128
Range on HMM: 5-243/425
Sequence Identity: 12% (29 aa)

GNFSYVYKVLKRLDG------------CLYSVKHSNWHLLN--------------------------EGDQRKALREVQALLCLS------CHENVVHYF
|.|. |...  ....              . .|  .   |                           . |... .||.. .  |.       |.|... .
GSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLY

SLWFK-------------------NDFLYIQI---------ELYES-LAWT--------------------FTEKKLIEVMFQLLNTFKHLHSHGLTHLD
  .                     ....|.           ||..  . .                     |||.    .. |..   ...|||.  |.|
EVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRD

VKLDKIYICNH------------------VYKIGNLGLA
 |.. | ....                    ||   |.|
LKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFA
Kinase WEE-S1_f.AA Ciliate-E2-Unclassified 1-111 16 1.4e-05 15.31 In-house 10-173 (352) Show / Hide 
Range on Protein: 1-111
Range on HMM: 10-173/352
Sequence Identity: 16% (27 aa)

GNFSYVYKVLKRLDGCLY---------------SVKHSNWHLLNEGDQRKAL---------REVQALLCLSCHENVVHYFSLWFKNDFLYIQIEL-----
|.|. |||. .. .. .|               ......  ..|| .. . .         .. | .|  . |...|..|    . . .||  |.     
GGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGD

---YESLAWT-----------------FTEKKLI-----EVMFQLLNTFKHLHSHG-LTHLDVKLD
   | .  ..                 |||.. .       . |.|. ...||. .   | | |..
LWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPE
Kinase WEE-S1_f.AA Ciliate-E1 65-117 26 1.6e-05 14.49 In-house 93-144 (202) Show / Hide 
Range on Protein: 65-117
Range on HMM: 93-144/202
Sequence Identity: 26% (14 aa)

LYIQIELYESLAWTFTEKKLIEVMFQLLNTFKHLHSHGLTHLDVKLDKIYICN
| . . ....    ||...... .|||.  .  ||.....|.| | ..| |.|
L-EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINN