Gene WEE-S1_a (S.moellendorffii)

WEE-S1_a

Species: S.moellendorffii
Alias: WEE-S1_a
External Links:
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
WEE-S1_a.AA Protein None 155 None Fasta, JSON
WEE-S1_a.NA RNA None 468 None Fasta, JSON
WEE-S1_a.kin_dom Protein Kinase Domain None 70 None Fasta, JSON

Protein domain

Protein domains of WEE-S1_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase WEE-S1_a.AA WEE 2-71 42 5.4e-27 87.64 In-house 12-88 (297) Show / Hide 
Range on Protein: 2-71
Range on HMM: 12-88/297
Sequence Identity: 42% (33 aa)

FSYVYKVLKRLDGCLYAVKHSNRRLLNEGD--QKALREVQALSCLG------YHENVVRYFSSWSENDFLYIQMKLCE
|. |||. .|.|||.||.| |  . ...    . |||||.|.. ||       |...|||.|.|.|.| .|||| .|.
FGEVYKCRCRIDGCIYAIKKSK-QPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCN
Kinase WEE-S1_a.AA WEE 104-141 47 6.3e-13 39.77 In-house 193-232 (297) Show / Hide 
Range on Protein: 104-141
Range on HMM: 193-232/297
Sequence Identity: 47% (19 aa)

EDGDLRYLPMELIND--DHSHLDKADMFSLGVTFYELARY
. || ||.. |....  ...|| ||| |||| |.||||..
QEGDSRYMAPEILQGYYHYTHLYKADIFSLGITIYELACN
Kinase WEE-S1_a.AA PEK 2-61 36 5.3e-11 33.8 In-house 12-87 (655) Show / Hide 
Range on Protein: 2-61
Range on HMM: 12-87/655
Sequence Identity: 36% (29 aa)

F-SYVYKVLKRLDGCLYAVKHSNRRLLNEGD-------------------QKALREVQALSCLGYHENVVRYFSSWSEND
|   ||||  .||||.||.|   |  ||  .                   .|.||||..|..|  |.|.|||...| |..
FGGQVYKVQNKLDGCYYAIK---RIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLN-HPNIVRYHNAWIEKP
Kinase WEE-S1_a.AA Pkinase 2-81 30 9.6e-10 35.53 Pfam 12-92 (293) Show / Hide 
Range on Protein: 2-81
Range on HMM: 12-92/293
Sequence Identity: 30% (25 aa)

FSYVYKVLKRLDGCLYAVKHSNRRLLNEGDQKALR---EVQALSCLGYHENVVRYFSSWSENDFLYIQMKLCEINLQDEMDIH
|. |||  .. .|...|||  ..|  ... ....|   |.| .  |. |.|.||.. .. ..| .|. | .||  |   || .
FGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLF
Kinase WEE-S1_a.AA HRI 5-59 41 6.3e-07 19.53 In-house 15-69 (613) Show / Hide 
Range on Protein: 5-59
Range on HMM: 15-69/613
Sequence Identity: 41% (23 aa)

VYKVLKRLDGCLYAVKHSNRRLLNEGD-QKALREVQALSCLGYHENVVRYFSSWSE
||||  .||.  ||.|    .     . .| .|||  | ||  | |.|||  .| |
VYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQ-HHNIVRYHQAWIE
Kinase WEE-S1_a.AA PEK 5-61 29 9e-07 17.34 In-house 15-78 (758) Show / Hide 
Range on Protein: 5-61
Range on HMM: 15-78/758
Sequence Identity: 29% (19 aa)

VYKVLKRLDGCLYAVKHSNRRL--------LNEGDQKALREVQALSCLGYHENVVRYFSSWSEND
|...   .|...||.|  .             .  .| .||| .|  |  | | ||||..| | .
VFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLD-HHNIVRYFNAWLETP
Kinase WEE-S1_a.AA IRE 34-76 35 1e-06 18.5 In-house 37-81 (292) Show / Hide 
Range on Protein: 34-76
Range on HMM: 37-81/292
Sequence Identity: 35% (16 aa)

ALREVQALS--CLGYHENVVRYFSSWSENDFLYIQMKLCEINLQD
. ||.|.|       |.||.||. . .  .|.|.   ||. .|||
ISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQD
Kinase WEE-S1_a.AA NEK4 5-71 38 2e-06 19.33 In-house 15-83 (257) Show / Hide 
Range on Protein: 5-71
Range on HMM: 15-83/257
Sequence Identity: 38% (27 aa)

VYKVLKRLDGCLYAVKHSNRR-LLNEGDQKALREVQALSCLGYHENVVRYFSSW-SEND-FLYIQMKLCE
|. | .| |.  | .|  . .    .  . |..|.| || |  | |.| |. || .||  |||| |  ||
VWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQL-KHPNIVEYKESWEIENGQFLYIVMGFCE
Kinase WEE-S1_a.AA GCN2 5-60 33 6e-06 16.28 In-house 15-73 (511) Show / Hide 
Range on Protein: 5-60
Range on HMM: 15-73/511
Sequence Identity: 33% (20 aa)

VYK-VLKRLDGCLYAVKHSNRRLLNEGDQK---ALREVQALSCLGYHENVVRYFSSWSEN
|.| |  ..||..||.|  . .  .. . .    .|||  |. |  |..||||. .| |.
VVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRL-HHQHVVRYYQAWIEK
Kinase WEE-S1_a.AA PEK-Unclassified 2-59 32 1.1e-05 14.54 In-house 12-74 (835) Show / Hide 
Range on Protein: 2-59
Range on HMM: 12-74/835
Sequence Identity: 32% (21 aa)

FSYVYKVLKRLDGCLYAVK--HSN----RRLLNEGDQKALREVQALSCLGYHENVVRYFSSWSE
|  ||..   .|   ||||  | |    .  |     | ..|| ..  .  | |..||. || |
FAIVYQCCHKFDQMEYAVKQIHVNIKDIKEDLQKHYEKEIMEVRYMAQV-NHPNIIRYYHSWIE
Kinase WEE-S1_a.AA S_TKc 2-152 13 2.3e-05 -98.16 SMART 12-231 (231) Show / Hide 
Range on Protein: 2-152
Range on HMM: 12-231/231
Sequence Identity: 13% (33 aa)

FSYVYKVLKRLDGCLYAVKHSNRRLLNEGDQKALREVQALSCLGYHENVVRYFSSWSENDFLYIQMKLCEI---NLQDEMDIHGKE-----ADRGNVSSL
|. |||. .. .| ..|.|  .        ....||.| |.    |.|.|... .. . |.||. | .|.    .| | .. .|..      .   . ..
FGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

TNQI-------------------------------------DGTISIEDGDLRYLPMELINDDHSHLD-KADMFSLGVTFYELAR---------------
. ||                                         .   | . |.. |..    ..   |.|. |.|...||..                
MYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKI

--------------------YSLPPVSG-------RQYQ
                    ..   .          .. 
GSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase WEE-S1_a.AA NEK 2-71 35 2.7e-05 15.06 In-house 12-89 (286) Show / Hide 
Range on Protein: 2-71
Range on HMM: 12-89/286
Sequence Identity: 35% (28 aa)

FSYVYKVLKRLDGCL-----YAVKHSNRRLLNE-GDQKAL-REVQALSCLGYHENVVRYFSSWSEND--FLYIQMKLCE
|. |||| .. ||       |. |  |   ..|   |.|.  ||. |. |  |.|.|.|. |. |..  .|.| |  ||
FGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQL-KHPNIVKYYDSFIEEQNNCLCIVMEYCE
Kinase WEE-S1_a.AA Ciliate-B2 90-132 20 3.9e-05 7.91 In-house 150-197 (197) Show / Hide 
Range on Protein: 90-132
Range on HMM: 150-197/197
Sequence Identity: 20% (10 aa)

VSSLTNQIDGTISIEDGDLRYLPMELINDD------HSHLDKADMFSLG
.||. .  .  |.|     .| . | ...|          ...| .|.|
ISSIKK-DNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase WEE-S1_a.AA HRI 62-76 60 0.016098 3.63 In-house 393-407 (613) Show / Hide 
Range on Protein: 62-76
Range on HMM: 393-407/613
Sequence Identity: 60% (9 aa)

FLYIQMKLCEINLQD
.|.|||.|||  | |
MLHIQMQLCELSLWD
Kinase WEE-S1_a.AA Pkinase 106-155 28 0.079416 7.54 Pfam 173-228 (293) Show / Hide 
Range on Protein: 106-155
Range on HMM: 173-228/293
Sequence Identity: 28% (16 aa)

GDLRYLPMELINDDHSHLDKADMFSLGVTFYELARYSLPPVSG------RQYQAIC
| ..|.. |.|...  .  |.||.|.|...||..   .|  .       .|.| ||
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMIC