STE-p1_b

Species: S.moellendorffii
Alias: STE-p1_b
External Links:
Annotation:

Classification

Group: STE
Family: STE-plant1

Sequence

Name Sequence Type Origin Length Description Download
STE-p1_b.AA Protein None 333 None Fasta, JSON
STE-p1_b.NA RNA None 1002 None Fasta, JSON
STE-p1_b.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of STE-p1_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc STE-p1_b.AA S_TKc 59-318 30 9.2e-92 312.08 SMART 1-231 (231) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-231/231
Sequence Identity: 30% (85 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDAAITKQIKREKEISMRSKAPYVVQCYGVFDKGGEISLVLEYMDG--GTLAHVLKRHPR-----
 |. ...|.|. |||||..|..|| ..|.| |.        ..|.|| .| .. . |..|..|.||.  ... .|.||.||  |.| ...|...|     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-IEEPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLHEARGGFNY-SADIWSLGLVL
 . |   . ... ....| |.||..|.|||.||.|.||..  ..||.|||....|       .||.||  ||.|| .       |... ..|.||.| .|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCIL

LQCALGYFPYLSHGQEADWMTLMCNICEWEVPSPPEGTSLEFQDLVKACLQKEPACRPNAFQLLQ-------HPFL
  .. || |.       . .... .|.           | |. |... ||||.|. || | ..||       ||..
YEMLCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase STE-p1_b.AA STE7 59-318 36 3.4e-89 302.62 In-house 1-288 (288) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-288/288
Sequence Identity: 36% (107 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDA-AITKQIKREKEISMRSK-APYVVQCYGVFDKGGE--ISLVLEYMDGGTLAHVLKRH-----
||. . || |..| |||..|. .|...|.|.|.   .  .. ||| .| .. ....  ||.||.|| | . |.  |....||||||.|  ..||      
LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVYR

----PRIEEPYLATITQYVLKGLLYLHS-NKIVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLHEARGGFNYSADIWS
     || |. |. |.  |.||| |||.  || |||.|||| |.||.|.||..|||.. .|  .  . .||||. .||.|||      . .    .|.||
GIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDG--NKQHYDVRSDVWS

LGLVL-LQCALGYFPY-------LSHGQEADW-------MTLMCNICEW-EVPSPPEGTSLEFQDLVKACLQKEPACRPNAFQLLQ-HPFL
||. . ...|.| .||       ..  | ..        ......| .  . |  | . | ||||.|. ||||.|  ||. .||.. |||.
LGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP-KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI

Kinase STE-p1_b.AA STE7-Unclassified 59-318 35 6.3e-89 301.75 In-house 1-301 (301) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-301/301
Sequence Identity: 35% (108 aa)

LEKREILGQGSGGKVYKVVHVR------TGVVYALKTIH-PKTDAAITKQIKREKEISMRSK-APYVVQCYGVFDKGGE---ISLVLEYMDGGTLA---H
||  ..|| |..|.|.|..|.       .|...|.|.|    .| .. ||| || ..    .  ||.|..|| .   .    | ...||||.|.|     
LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLHKCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKID

VLKRH--------PRIEEPYLATITQYVLKGLLYLHSNK-IVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLH-EARG
..|.          .| || |. |.  |..|| |||  . |.||||||.|.|.||||.|||.||||. .| .|  | .|.||.  ||||||..     | 
IYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPHRP

GFNYSADIWSLGLVLLQCALGYFPYL----SHGQEAD-------WMTLMCNICEWEVPSPPEGT-----SLEFQDLVKACLQKEPACRPNAFQLLQ-HPF
.     |||||||... ||.| .||     | ....          .|  .| . .||  |. .     | ||.|... |..|.|  || ..|||  ||.
SYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHPW

L
.
I

Kinase STE-p1_b.AA STE 59-318 28 5.8e-84 285.25 In-house 1-359 (359) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-359/359
Sequence Identity: 28% (103 aa)

LEKREILGQGSGGKVYKVVHVR---------------TGVVYALKTIHPKTDA----------------AITKQIKREKEISMRSK--APYVVQCYGVFD
.|. |..|.|..|.||| ...                ||...| | .. ...                  . .||..| .| ....   |..|..|| . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KGG-------EISLVLEYMDGGTLAHVLKRH--------------PRIEEPYLATITQYVLKG-LLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVST
|.|       |. ...||||||.|  ..|.                |..|. .|.|.. .||| | ||||..|.||||||.| ||     ||..||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ELASTFA----------------ECNTFVGTCAYMSPERFKLHEAR--GGFNYSADIWSLGLVLLQCALGYFPYLS-HGQEADWMTLMCNICEW------
 |... |                ..||||||  .|.||. .  .    .| ....||||||....  | |  |.   |  .| .|... .....      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----EVPSPPEGTS-------------------LEFQDLVKACLQKEPACRPNAFQLLQ--HPFL
    . |. |. .|                    ||.| .. ||||.|  ||.| |||.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase STE-p1_b.AA Pkinase 59-318 28 1.4e-71 248.96 Pfam 1-293 (293) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDAAITKQIKR---EKEISMRSKAPYVVQCYGVFDKGGEISLVLEYMDGG----TLAHVLK--RH
... ...|.|| |.||| .|. || ..|.|.|  ...    .|..|   | .|  | . |..|..|..|  ...| .|.||..||     |.....  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PRI--EEPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEV----KIADFGVSTEL-ASTFAECNTFVGTCAYMSPERFKLHEARGGFNYSADI
 ..  .|  .  .   .|.|| |.||..|.|||.||.|.|....|..    ||.|||..  .       ..||.||  ||.||  .    . .  ...|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDM

WSLGLVLLQCALGYFPYLSHG----QEADWMTLMCNICEWEVPSPPEGTS--------------------LEFQDLVKACLQKEPACRPNAFQLLQHPFL
||.|..| . ..|..|.  .       .| | ..|.| . ..... . ..                     |..|..| ||.| |..||.| |.||||..
WSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF





Kinase STE-p1_b.AA MEK1 59-258 47 5.1e-62 210.62 In-house 1-195 (297) Show / Hide
Range on Protein: 59-258
Range on HMM: 1-195/297
Sequence Identity: 47% (95 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDAAITKQIKREKEISMRSKAPYVVQCYGVFDKGGEISLVLEYMDGGTLAHVLKRHPRIEEPYLA
.|| . ||.| || | |..| .||.. | | ||     || .|| || ..  .   ||.|  || |   ||||. .|||||| |  |||.  || |  | 
FEKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEYMDGGSLDQVLKKAGRIPEKILG

TITQYVLKGLLYLHSN-KIVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLHEARGGFNYSADIWSLGLVLLQCALGYF
 ..  ||.|| ||. . ||.|||.||||.| ||.||.|. |||||  |    |  | |||| .|||||| .       .  ..||||.|| |   |.| .
KVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA--NSFVGTRSYMSPERLQGTH----YTVQSDIWSMGLSLVEMAIGRY

P
|
P

Kinase STE-p1_b.AA MEK5 59-318 38 1.5e-61 210.8 In-house 1-254 (254) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-254/254
Sequence Identity: 38% (101 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDAAITKQIKREKEISMRSKAPYVVQCYGVFDKGGEISLVLEYMDGGTLAHVLKRHPRIEEPYLA
.  |. || | || |||  || .| . |.| |       . |||  | ||  .  .||..  || |     ||.  |.|||| |    .    | |  | 
IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSPYIIGFYGAFFVENRISICTEFMDGGSLDMYRC----IPEHILG

TITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLHEARGGFNYSADIWSLGLVLLQCALGYFP
 .|  . ||| || . ||.|||.||||.| | .|..|. |||||| | .  .   |..|| ||| |||    .    .   .|.||||. ..  |.| ||
RMTVAIVKGLNYLWNLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITR--TYIGTNAYMAPERISGDQ----YGIHSDVWSLGIFFMEMATGRFP

Y--LSHGQ-EADWMTLMCNICEWEVPSPPEGT-SLEFQDLVKACLQKEPACRPNAFQLLQHPFL
|  . . | |   . |.  | . . |  | .  |  | . .  |.|| |  ||   .|.||||.
YPQIQRDQGELMPIQLLQCIVDEHPPRLPVDKFSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI

Kinase STE-p1_b.AA CAMK 64-318 18 3.5e-59 189.02 In-house 1-425 (425) Show / Hide
Range on Protein: 64-318
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

ILGQGSGGKVYKVVHVRTG------------VVYALKTIHPK---------------------------TDAAITKQIKREKEISMRSK-------APYV
.||.|| |||....| .|.            . .| | |  |                           ...   |...|| || .. .        | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQCYGVFDKGG-------------------EISLVL---EYMDGG----TLAHVLKRHPR---------------IEEPYLATITQYVLKGLLYLHSNKI
...| |.. .                    .. .|.   ||..||     |   ...|..               ..|   ... . .. .. |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPSNLLLNSK-----------------GEVKIADFGVSTELAS-----------------------TFAECNTFVGTCAYMS-PERFKL------
||||.|| |.||...                 . .||.||| .... .                       .   ..||.|| .||. || ..       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----HEARGGFNYSADIWSLGLVLLQCALGYFPYLSHGQEADW---------MTLMCNICEWEVPSPPEGTSL-----------------------EFQD
     | . . ....|.||.| .|  .  ||.|. .  .. .            |. .|.. .   ||.  |                        | .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVKACLQKEPACRPNAFQLLQHPFL
|.. .||..|  |... | |.||..
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase STE-p1_b.AA Ciliate-E2 59-318 22 8.1e-58 197.05 In-house 1-365 (365) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

LEKREILGQGSGGKVYKVVHVRTGV-----------------------VYALKTIHPKTDAAITK---QIK---------REKEISMRSKAPYVVQCYGV
 .. ...|||. |.|||. . ...                         ||.|.....   .| .   ...          ||.|  . . |.....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FD--KGGEISLVLEYMDGGTLAHVLK------------RHPRIEEPYLATITQYVLK---------------GLLYLHSNK-IVHRDIKPSNLLLNSKGE
|   .   | ||.|| .||.| . .|               .. |   ..|....|.               .| ||||.. |.||||||.|.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIADFGVSTELAS-------------------------------TFAECNTFVGTCAYMSPERFKLHE-----ARGGFNYSADIWSLGLVLLQCALGYF
.||.||| |...                                  .   ||..||  ||.|| ..  .     .. | .|..|||||| .| ..  |..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYLSHGQEADWMTLMCNIC--EWEVPSP---------------PEGTSLEFQDLVKA----CLQKEPACRPN-AFQLLQHPFL
|.            . .|.  ... |.|               ..  |.| .|| |     .|||.|  |.. . |.|.||..
PF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase STE-p1_b.AA STE20 59-246 38 3.6e-54 186.3 In-house 1-214 (288) Show / Hide
Range on Protein: 59-246
Range on HMM: 1-214/288
Sequence Identity: 38% (84 aa)

LEKREILGQGSGGKVYKVVHVRTGVV----YALKTIHPKTD---AAITKQIKREKEISM--RSKAPYVVQCYGVFDKG----GEISLVLEYMDGGTLAHV
 |. | .|||| |||||. |..|| .    .| | .  ...       ..   .||||.  ..| |..|. || . |.     |. .| ||..||.|  .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ--DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDI

LK---RHP------RIEEPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVSTELAS----TFA-ECNTFVGTCAYMSPERFKLHE
.|   ..       ...|.. |.|.. ||.|| |||||.|.|||||  | ||...||||.|||||.  | .    |.. . ||||||  .|.||  .  |
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

A-RGGFNYSADIWSLG
  ..| .| .||||||
GPDKGYDYKCDIWSLG

Kinase STE-p1_b.AA Ciliate-E2-Unclassified 60-318 24 1.3e-53 184.31 In-house 2-352 (352) Show / Hide
Range on Protein: 60-318
Range on HMM: 2-352/352
Sequence Identity: 24% (86 aa)

EKREILGQGSGGKVYKVVHVRTGVVYALKTIH----------PKTDAAITKQIKREKEIS---------------MRSKAPYVVQCYGVFDKGGEISLVL
.. ...|||. |||||..|  .. .||.|...           . |  |  ..|......                 .. |..| .. .| .   | .|.
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYMDGGTLAHVLK----------------RHPRIEEPYLA------TITQYVLKGLLYLHSNK-IVHRDIKPSNLLLNSKG---EVKIADFGVSTELAST
||..||.|   .|                .. .| . . |      ... ..|.|| |||... |.||||||.|.|....|   ..||.||| | .. . 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------FAECNTFVGTCAYM----SPERFKLHEARGGFN----YSADIWSLGLVLLQCALGYFPYLSHGQEA------------DWMTLMC
               . ...||.||  ||    .|| ..    . . .    |..|||||| .| ..  ||.|. .  .|             . . |  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ----GQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

NICE--WEVPSPPE-----GTSLEFQDLVK----ACLQKEPACRPNAFQLLQHPFL
||..  ...|. |.     . | | .|...     .|.| |  |... |.|.||..
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase STE-p1_b.AA MST 60-246 41 2.1e-48 151.91 In-house 2-184 (254) Show / Hide
Range on Protein: 60-246
Range on HMM: 2-184/254
Sequence Identity: 41% (80 aa)

EKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTD-AAITKQIKREKEISMRS--KAPYVVQCYGVFD--KGGEISLVLEYMDGGTLAHVLKRHPR-IE
.. |.||||| |.||| .|  || ..| | .   .|  .|      .||||. .  | .|.|. || .   |  .. .| || ..| .. . |   |   
DIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEI------IKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLN

EPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVSTELASTFAECNTFVGTCAYMSPERFKLHEARGGFNYSADIWSLG
|   |.| . .|.|| |||.||..|||||. | ||| .|| | |||||| .|  | |. ||..||  .|.||   . |   . .. |||||||
EQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEV--IQEI--KYDCKADIWSLG

Kinase STE-p1_b.AA TyrKc 59-318 21 9.1e-15 16.06 SMART 1-280 (280) Show / Hide
Range on Protein: 59-318
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

LEKREILGQGSGGKVYKVVHVRTGVVYALKTIHPKTDAAITKQIKREKEISMRS--KAPYVVQCYGVFDKG-------GEISLVLEYMDGGTLAHVLKRH
... ..|| |  |.||| .     .  | |.... .     . . || .| ..   . | .|..|||  ..       . . .|.|||..| | . |..|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

PR-IEEPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVSTELAST---------FAE----CNTFVGTCAYMSPERFKLHEARGG
 . .  . |  .   . .|  ||||....|||.   | |..... |||.||| | .. .                 .  ..     |.|| .      | 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGK

FNYSADIWSLGLVL--LQCALGYFPYLS---HGQEADWMTLMCNICEWEVPSPPEG--------TSLEFQDLVKACLQKEPACRPNAFQLLQHPFL
|.   |.|| | ..  . . .|  ||     .    ..  .. .. . . . .|.          . |  .. | | . .|..||.  ..  | ..
FTTKSDVWSFGVCMWEI-FTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase STE-p1_b.AA Pkinase_Tyr 59-202 27 8.3e-14 47.39 Pfam 1-158 (270) Show / Hide
Range on Protein: 59-202
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

LEKREILGQGSGGKVYKVVHV----RTGVVYALKTIHPKTDAAI--TKQIKREKEISMRSKA---PYVVQCYGVFD-KGGE--ISLVLEYMDGGTLAHVL
... . ||.|. |.||| .       |..  | |.. ....      .   |  |... ..    | .|..|||   .|.   | .|.||| .| | . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KRH----PRIEEPYLATITQYVLKGLLYLHSNKIVHRDIKPSNLLLNSKGEVKIADFGVS
..|    ...  . |  . . . ||. ||.|....|||.   | |..... |||.||| .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase STE-p1_b.AA STE20 288-318 61 2.2e-12 41.86 In-house 258-288 (288) Show / Hide
Range on Protein: 288-318
Range on HMM: 258-288/288
Sequence Identity: 61% (19 aa)

SLEFQDLVKACLQKEPACRPNAFQLLQHPFL
| ||.|.|. ||||.|. || | |||.|||.
SPEFHDFVDKCLQKDPEKRPTASQLLKHPFI

Kinase STE-p1_b.AA MST 288-318 61 1.5e-11 32.88 In-house 224-254 (254) Show / Hide
Range on Protein: 288-318
Range on HMM: 224-254/254
Sequence Identity: 61% (19 aa)

SLEFQDLVKACLQKEPACRPNAFQLLQHPFL
| || | |. ||||.|  |. | ||||||| 
SQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI

Kinase STE-p1_b.AA MEK1 288-318 48 2e-06 17.16 In-house 267-297 (297) Show / Hide
Range on Protein: 288-318
Range on HMM: 267-297/297
Sequence Identity: 48% (15 aa)

SLEFQDLVKACLQKEPACRPNAFQLLQHPFL
| |||| |. ||.|.|. | .  ||..|.|.
SEEFQDFVDKCLIKNPDERADLKQLMVHTFI