CR4L_e-2

Species: S.moellendorffii
Alias: CR4L_e-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: CR4L

Sequence

Name Sequence Type Origin Length Description Download
CR4L_e-2.AA Protein None 822 None Fasta, JSON
CR4L_e-2.NA RNA None 2469 None Fasta, JSON
CR4L_e-2.kin_dom Protein Kinase Domain None 208 None Fasta, JSON

Protein domain

Protein domains of CR4L_e-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CR4L_e-2.AA IRAK 501-710 37 3.2e-64 219.66 In-house 1-223 (317) Show / Hide
Range on Protein: 501-710
Range on HMM: 1-223/317
Sequence Identity: 37% (87 aa)

FSDDNRIGTGSFGTVYRGVLPDGRE--VAIKRGGVGSSGMDAIAKKKFQDKESAFQS---ELEFLTRLHHRHLVTLVGFCAEDDERLLVYDFMPNGTQQE
|. ||||| | ||.||||.. .. .  .|.|.         . |. ..  ..  ||.   ||. ..|..| ..| | |.|.| ..  |||..||||. . 
FHKDNRIGEGGFGCVYRGQW-KNTTGIYAVKK-------LKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLED

RIFAIN-LNS-----WQMRIGIALQAARGIEYLHTYA-VPPIIHRDIKSSNILIDAECSARVSDFGLSLMG-PSDGESHLSL------TAAGTVGYMDPE
|  . .  ..     |..|. |.. .|.||..||.     ||||.||||.||| |.   .  .||||   | |  .  . ..      .  ||  || ||
RLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPE

YYR--LQQLTTKSDVYSFGVVLLEILTGKRA
. |    |||.|.||||||.||||.||| ||
FIRDPQGQLTKKTDVYSFGIVLLEVLTGCRA

Kinase CR4L_e-2.AA TKL 507-790 23 6.6e-62 211.99 In-house 1-364 (364) Show / Hide
Range on Protein: 507-790
Range on HMM: 1-364/364
Sequence Identity: 23% (91 aa)

IGTGSFGTVYRGVLPD---------GREVAIKRGGVGS------------------SGMDAIAKKKFQDKESAFQSELEFLTRLHHRHLVTLVGFCAEDD
|| |.||.||.|..           |..||.|.  . .                    |  .  .. .  .  .  |.  . ||.| ..| ..|.| . .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSD-M-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP

E-------------RLLVYDFMPNGTQQERIFAINLNSWQMRIGIALQAARGIEYLHTYAV-----PPIIHRDIKSSNILID--------------AECS
                .|....|.|.  ...       |. |. .||..|||..|||.        |||||||.||.|||.|              |.. 
CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

ARVSDFGLSL-MGPSDGESHLSLT----------------AAGTVGYMDPEYYRLQ----------------QLTTKSDVYSFGVVLLEILTGKRAIIVE
. ..|||||  | .| . .. . |                  || ..| ||  | |                . ..|.||||||.|| ||||..|     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

NRLKLRQNPQLPVNVVDFAVPFILAGQVISILDPRIG-VPEE----ADEMEAVLIVAELAEECVRLEGKERPSMGEIVSRL
     ...|  |. . |  .  .... .   | | |  ....     ..  .   ...|...|   . ..|||. ||..||
---PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase CR4L_e-2.AA TKL-Unique 503-709 29 5.7e-40 138.67 In-house 1-226 (290) Show / Hide
Range on Protein: 503-709
Range on HMM: 1-226/290
Sequence Identity: 29% (70 aa)

DDNRIGTGSFGTVYRGVLPDGREVAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRLH-HRHLVTLVGFCA----EDDERLLVYDFMPNGTQQERI
. | ||.|..|.||.|. . | .||||.  .  ..   . ...       | .|.  . .|| |  .|...|.|.       .. .| ...| |.  . .
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHP-NEDSSNEMMQE-------FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL

F----------AINLNSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAE-----CSARVSDFGLSLMGPSDGESHLS-------LTAAGTV
             . ...|.|. .|...|.| .|||..  | |||||.||||.|.| .      .....|||||    .. .. ..        |  |. 
HQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF

GYMDPEYYRL--QQLTTKSDVYSFGVVLLEILTGKR
 .| ||  |    | ..||||||||.|| ||.|.|.
RWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI

Kinase CR4L_e-2.AA Pkinase 501-708 27 1.3e-36 130.53 Pfam 1-209 (293) Show / Hide
Range on Protein: 501-708
Range on HMM: 1-209/293
Sequence Identity: 27% (61 aa)

FSDDNRIGTGSFGTVYRGVLPDGRE-VAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRLHHRHLVTLVGFCAEDDERLLVYDFMPNG----TQQE
.    .|| ||||.||...  . .. ||.|.  . .  ..    .          ||.. . ||.| . |.| ... ..|.  .| .....|       .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

RIF--AINLN--SWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSA----RVSDFGLSLMGPSDGESHLSLTAAGTVGYMDPEYYR-LQ
.|   . .    |..  . ...| .||.||.|      |||||.|..||||| ..      ...||||.        ..   | .|| .|| ||  |  |
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQ

QLTTKSDVYSFGVVLLEILTGK
  ..|.|..|.|..| | |.|.
YYGPKVDMWSCGCILYEMLCGR

Kinase CR4L_e-2.AA MLK 501-708 28 1.7e-33 113.65 In-house 1-233 (291) Show / Hide
Range on Protein: 501-708
Range on HMM: 1-233/291
Sequence Identity: 28% (70 aa)

FSDDNRIGTGSFGTVYRGVLPDGRE-----VAIKRGGVGSSGMDAIAKKKFQDKESA------FQSELEFLTRLHHRH----LVTLVGFCAEDDE-RLLV
.     || |||| |..|.   ...     ||.||          ..  .| || ..      |. | . | .| |.      . ..| |...    ..|
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKR----------VRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIV

YDFMPNGTQQERIFAINL--------------NSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDA------ECSARVSDFGLSLMGPSDGE
  ....|   . . ...                . .  . .||| |||..|||  |..||||||.||.|||||.      .  ....|||.| .  . . 
MEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-

S-HLSLTAAGTVGYMDPEYY---RLQQLTTKSDVYSFGVVLLEILTGK
. . |  .|||. .| ||     | .. . |.||.|.|||| |.||..
TNMMS--NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE

Kinase CR4L_e-2.AA TK 501-706 15 6.3e-32 103.74 In-house 1-389 (486) Show / Hide
Range on Protein: 501-706
Range on HMM: 1-389/486
Sequence Identity: 15% (61 aa)

FSDDNRIGTGSFG---TVYRGVLPDGR--------------------------EVAIKRGGVGSSGMDAIAKK-KFQDKESA--------FQSELEFLT-
    . .| | ||   .||.| . ...                          .||.|    |..  ..  .   ..|            . .|.. .  
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHD---RDGGEDFLEEAEEMKMMCH

-RLHHRHLVTLVGFCAEDDE------------RLLVYDFMPNGT---------QQERIFAINLNS-----------------------------------
  .|| ..| |.| | ....             ..|  .||.|          .. |  ...  .                                   
SLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEE

------------------------------------WQMRIGIALQAARGIEYLHTYAV---PPIIHRDIKSSNILIDAECS-----------ARVSDFG
                                     . .. ...|.|.| ||||   .   . ..|||.   |.|.. .             ....|||
QDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG

LSLMGP----SDGESHLSLTAAGTVG----------------------------YMDPEYYRLQQ---------LTTKSDVYSFGVVLLEILT
|| .|      | .|.   ..... |                            .| ||  . ..          ||||||.||||.. ||.|
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase CR4L_e-2.AA LRRK 501-710 25 6e-31 106.71 In-house 1-282 (351) Show / Hide
Range on Protein: 501-710
Range on HMM: 1-282/351
Sequence Identity: 25% (74 aa)

FSDDNRIGTGSFG-TVYRGVLPD---------------------------GREVAIKRGGVG----------SSG-----------------MDAIAKKK
.   . || |.|| .|||. . .                           . .||||   ..          |..                  .. . ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FQDKESAFQSELEFLTRLHHRHLVTLVGFCAEDDERLLVYDFMPNGTQQERIFAIN---L-----N-SWQMRIGIALQAARGIEYLHTYAVPPIIHRDIK
|.     |. |.  . .|.| ..| |.||| .   . .| ...|.|. ......     .     . ||.... |||| |.|.||||  . ||||||| |
FRE----FRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLK

SSNILI---D---------AECSARVSDFGLSLMGPSDGESHLSLTAAGTVGYMDPEYYRLQ---QLTTKSDVYSFGVVLLEILTGK-RA
| |||.   .         |.  | ..|||.| |  .   . .  .  |. |.| ||  |     . |.|.|.||||..| |.||.. ..
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase CR4L_e-2.AA RIPK 507-710 26 4.4e-30 99.7 In-house 1-227 (290) Show / Hide
Range on Protein: 507-710
Range on HMM: 1-227/290
Sequence Identity: 26% (62 aa)

IGTGSFGTVYRGVLPDGREVAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRLHHRHLVTLVGFCAEDDE------RLLVYDFMPNGTQQE-RIFA
.| |.||.|.. .  . .....|     . .   ...   . .. .   | . . .| ..| | . ||| . .         .|  .|.||   . ..  
VGGGGFGEVFKARHRHWGDWVAKKC---KPCKHCHTHM-DDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTK

INL----NSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLS-LMGPS--DG--------ESHLSLTAAGTVGYMDPEYYR
.        |  |  .  . ..|  |||    ||||||| | .|||.|..  . ..||||.  |. |   .         |  |.   ||  ||.|| .|
WPYQHHPDPWPLRCRMIHEISCGMCYLHSMN-PPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFR

--LQQL----TTKSDVYSFGVVLLEILTGKRA
  .       |.|.|||||..|. |.||.| .
TDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase CR4L_e-2.AA Dicty4 604-708 44 1.1e-28 92.89 In-house 107-214 (277) Show / Hide
Range on Protein: 604-708
Range on HMM: 107-214/277
Sequence Identity: 44% (49 aa)

SWQMRIG---IALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLSL-MGPSDGESHLS--LTAAGTVGYMDPEYYRLQQLTTKSDVYSF
.|  ..    .|. ||||. .||.   | |||||.||.|.|.|.   . |.|||||  | .  .|.|     ||.||...| ||  . |  . |.|||||
DWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKK--HEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSF

GVVLLEILTGK
| || ||||..
GIVLWEILTRQ

Kinase CR4L_e-2.AA Dicty4-Unclassified 504-707 30 3.8e-28 93.47 In-house 4-204 (263) Show / Hide
Range on Protein: 504-707
Range on HMM: 4-204/263
Sequence Identity: 30% (67 aa)

DNRIGTGSFGTVYRGVLPDGREVAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRLHHRHLVTLVGFCAED----DERLLVYDFMPNGTQQERIF-
|  || | |  |..|.   |..||.|      .. .       ||    |  | | |  . |  ||.. | |            |  ||. |.  | |  
DQFIGKGHFSKVHKGNW-KGKDVAVK---KFNENKFKFREEMIQD----FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHS

-------AINLNSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLSLMGPSDGESHLSLTAAG-TVGYMDPEYYRLQQLTT
        | |..  . | .|.  |.|. .|||     .|||||||||||.|    ... |||.|       .    .|. . |.    ||  .    . 
KPSEQQQPIKLDD-TLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRV----IDFNFNMTTIAGTPKWESPECLMHESYNQ

KSDVYSFGVVLLEILTG
||||||....| | .||
KSDVYSYAMMLYELATG

Kinase CR4L_e-2.AA TyrKc 501-790 22 3e-27 97.78 SMART 1-280 (280) Show / Hide
Range on Protein: 501-790
Range on HMM: 1-280/280
Sequence Identity: 22% (74 aa)

FSDDNRIGTGSFGTVYRGVLPDGREVAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRL--HHRHLVTLVGFCAED-------DERLLVYDFMPNG
 . .  .| | ||.||.|..   ..||.|    ..              . .| .|.. ...|  || ..| |.| | ..       .  ..|  .||.|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

TQQERI-FAINLNSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLSLMGPSD---GESHLSLTA----AGT----VGYMD
  ....    .  ...  . ...|.|.| ||||     ..||||.   |.|....  ...||||||  . .|   |||.   ..     |     .  | 
DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEYYRLQQLTTKSDVYSFGVVLLEILT-------G-----KRAIIVENRLKLRQNPQLPVNVVDFAVPFILAGQVISILDPRIGVPEEADEMEAVLIVAE
||  .    ||||||.||||.. ||.|       |     . .. | ...| .  .  | |.     | .                      ..   . .
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MS-----------------F--VCCPDEMYQ

LAEECVRLEGKERPSMGEIVSRL
. ..| . . ..||.. ||....
IMKQCWHEDPEDRPTFSEIHECF

Kinase CR4L_e-2.AA S_TKc 501-794 19 2.1e-23 84.97 SMART 1-231 (231) Show / Hide
Range on Protein: 501-794
Range on HMM: 1-231/231
Sequence Identity: 19% (61 aa)

FSDDNRIGTGSFGTVYRGVLPD-GREVAIKRGGVGSSGMDAIAKKKFQDKESAFQSELEFLTRLHHRHLVTLVGFCAEDDERLLVYDFMPN--GTQQERI
.   . || |.||.||...  . ||.||||.                      ...|.. | . || ..|.| ... . |.  .| .....  |.  ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

FAIN-------LNSWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLSLMGPSDGESHLSLTAAGTVGYMDPEYYRLQQLTT
   .       ..  . |  .. | ....||.|      |||||.| .|||.|      ..||||.             |  ||  || ||     . ..
KKRGRHGLRFPFPE-HARF-YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGK

-KSDVYSFGVVLLEILTGKRAIIVENRLKLRQNPQLPVNVVDFAVPFILAGQVISILDPRIGVPEEADEMEAVLIVAELAEECVRLEGKERPSMGEIVS-
 |.|..|.|..| | |.|.      .  .. ..                                          . .. . | . . ..||.  |.   
CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

----RLESAV
    ..   .
EWDIKCHPWF

Kinase CR4L_e-2.AA DRK 604-706 39 1.4e-22 73.31 In-house 96-197 (258) Show / Hide
Range on Protein: 604-706
Range on HMM: 96-197/258
Sequence Identity: 39% (41 aa)

SWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLSLMGPSDGESHLSLTAAGTVGYMDPEYYRLQQLTTKSDVYSFGVVLLE
.|  .. ... .|.|. |||    | ||||| || | |.|      |.|||||       .     |. || .   ||  | |  | | |||||..|| |
DWPLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWE

ILT
..|
CVT

Kinase CR4L_e-2.AA Pkinase_Tyr 501-591 23 8e-12 40.66 Pfam 1-92 (270) Show / Hide
Range on Protein: 501-591
Range on HMM: 1-92/270
Sequence Identity: 23% (24 aa)

FSDDNRIGTGSFGTVYRGVLP-----DGREVAIKRGGVGSSGMDAIAKKKFQDKE---SAFQSELEFLTRL-HHRHLVTLVGFCA-EDDE--RLLVYDFM
 . .  .| |.||.||.|..      .. .||.|           . | .  ...    .| .|.. .. | || ..| |.| |  ...    ..|  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK-----------MLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYM

PNG
|.|
PHG

Kinase CR4L_e-2.AA ABC1 507-529 45 1.1e-05 21.41 Pfam 19-42 (126) Show / Hide
Range on Protein: 507-529
Range on HMM: 19-42/126
Sequence Identity: 45% (11 aa)

IGTGSFGTVYRGVLPD-GREVAIK
|...| . |.|..|.| |.|||.|
IAAASIAQVHRARLKDDGEEVAVK

Kinase CR4L_e-2.AA Pkinase_Tyr 604-656 30 1.4e-05 19.52 Pfam 109-158 (270) Show / Hide
Range on Protein: 604-656
Range on HMM: 109-158/270
Sequence Identity: 30% (16 aa)

SWQMRIGIALQAARGIEYLHTYAVPPIIHRDIKSSNILIDAECSARVSDFGLS
. .. .....| |.| |||.      .||||.   |.|.. .  ....||||.
TMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLA

Kinase CR4L_e-2.AA Pkinase_Tyr 689-706 72 7.4e-05 17.08 Pfam 192-209 (270) Show / Hide
Range on Protein: 689-706
Range on HMM: 192-209/270
Sequence Identity: 72% (13 aa)

TTKSDVYSFGVVLLEILT
||||||.||||.. ||.|
TTKSDVWSFGVLMWEIFT

Kinase CR4L_e-2.AA DRK 766-792 37 7.6e-05 12.38 In-house 232-258 (258) Show / Hide
Range on Protein: 766-792
Range on HMM: 232-258/258
Sequence Identity: 37% (10 aa)

AELAEECVRLEGKERPSMGEIVSRLES
. |  .|   .   |||| |.. |||.
IQLMNDCWNEDPQHRPSMQECLERLEA

Kinase CR4L_e-2.AA Dicty4 501-529 51 8.1e-05 12.2 In-house 1-28 (277) Show / Hide
Range on Protein: 501-529
Range on HMM: 1-28/277
Sequence Identity: 51% (15 aa)

FSDDNRIGTGSFGTVYRGVLPDGREVAIK
   ..|||.||||.||.|    | |||.|
INIEQRIGKGSFGEVYKGTWR-GKEVAVK

Kinase CR4L_e-2.AA TK 757-790 14 8.5e-05 11.18 In-house 453-486 (486) Show / Hide
Range on Protein: 757-790
Range on HMM: 453-486/486
Sequence Identity: 14% (5 aa)

DEMEAVLIVAELAEECVRLEGKERPSMGEIVSRL
.. ..  ....|  .| ... ..||.. .....|
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase CR4L_e-2.AA Dicty4 778-792 47 0.000141 11.38 In-house 261-277 (277) Show / Hide
Range on Protein: 778-792
Range on HMM: 261-277/277
Sequence Identity: 47% (8 aa)

KERPSMGEIVSR--LES
. |||. ||..|  ||.
QHRPSFEEIIQRRILEH

Kinase CR4L_e-2.AA DRK 504-530 48 0.000691 9.09 In-house 4-29 (258) Show / Hide
Range on Protein: 504-530
Range on HMM: 4-29/258
Sequence Identity: 48% (13 aa)

DNRIGTGSFGTVYRGVLPDGREVAIKR
 |||| |..| |.||    | .||.|.
GNRIGRGNYGEVFRGTW-RGTQVAVKM

Kinase CR4L_e-2.AA LRRK 778-792 46 0.004271 6.78 In-house 337-351 (351) Show / Hide
Range on Protein: 778-792
Range on HMM: 337-351/351
Sequence Identity: 46% (7 aa)

KERPSMGEIVSRLES
|.||.. .||.||..
KKRPHFSQIVKRLSQ

Kinase CR4L_e-2.AA MLK 766-790 32 0.005162 6.45 In-house 267-291 (291) Show / Hide
Range on Protein: 766-790
Range on HMM: 267-291/291
Sequence Identity: 32% (8 aa)

AELAEECVRLEGKERPSMGEIVSRL
..| ..|   . ..|||. .||. |
KKLMKQCWNQDPHKRPSFRQIVQHL

Kinase CR4L_e-2.AA Dicty4-Unclassified 778-790 38 0.036933 3.15 In-house 251-263 (263) Show / Hide
Range on Protein: 778-790
Range on HMM: 251-263/263
Sequence Identity: 38% (5 aa)

KERPSMGEIVSRL
. ||.| .|. .|
NKRPTMNQIIQYL

Kinase CR4L_e-2.AA TKL-Unique 770-790 38 0.090581 2.24 In-house 270-290 (290) Show / Hide
Range on Protein: 770-790
Range on HMM: 270-290/290
Sequence Identity: 38% (8 aa)

EECVRLEGKERPSMGEIVSRL
..| . .  .|||  ||..||
QQCWHHDPSQRPSFDEIIHRL

Kinase CR4L_e-2.AA IRAK 768-790 21 0.093684 2.2 In-house 295-317 (317) Show / Hide
Range on Protein: 768-790
Range on HMM: 295-317/317
Sequence Identity: 21% (5 aa)

LAEECVRLEGKERPSMGEIVSRL
.| .|.    ..|..| . ...|
CACCCGHHRANRRCDMAWVMQQL

Kinase CR4L_e-2.AA Pkinase_Tyr 778-790 38 0.491012 4.13 Pfam 258-270 (270) Show / Hide
Range on Protein: 778-790
Range on HMM: 258-270/270
Sequence Identity: 38% (5 aa)

KERPSMGEIVSRL
..||.. ||...|
EDRPTFSEIHEQL