Gene CR4L_a-2 (S.moellendorffii)

CR4L_a-2

Species: S.moellendorffii
Alias: CR4L_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: CR4L

Sequence

Name Sequence Type Origin Length Description Download
CR4L_a-2.AA Protein None 439 None Fasta, JSON
CR4L_a-2.NA RNA None 1320 None Fasta, JSON
CR4L_a-2.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of CR4L_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CR4L_a-2.AA TKL 48-310 21 2.4e-57 196.83 In-house 1-364 (364) Show / Hide 
Range on Protein: 48-310
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

LGKGSYGWVYKGCLRD---------GKLVAVKRSSL-------------------------ARKNSQDDNPLDNELEILSKIRSTRLVNLVGYSRDNKE-
.|.|..| |||| .|          || ||||. .                          ....|.    . .|. ..|..|   .| ..||. ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------TVLVVDYMANGTLHDILHCRNEPLSWSIRVQVALQIAKGLRALHSAS------PPVIHRDIKSSNVLIDADWN--------------A
              .| .|. .|.|...||       |. |.. ||.||.|.  |||        ||.||||.||.|.|.| .|.              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RLADFGLAL-RGRIEDVIRLSTP----------------PAGTMGYLDPGYVSPG----------------HLSTKTDVFSFGILLLEIMSGRNAIDVQY
 ..||||.    . ..  . .|                 . || ... |                        |.|.||.||||.| ||....   . . 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

YPPNIVD----WALPLIKQGKGAAICDPKSKH----PTNAEALNEMAGVAARCVRLSSSRRPTMAEVVKEL
|.| |.     . . .. . .    ..|  ..    . .  .. .|.  . .|     . ||.. |..|.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase CR4L_a-2.AA IRAK 42-310 26 8.8e-57 194.96 In-house 1-317 (317) Show / Hide 
Range on Protein: 42-310
Range on HMM: 1-317/317
Sequence Identity: 26% (85 aa)

FAREFLLGKGSYGWVYKGCLRDGK-LVAVK--RSSLARKNSQDDNPLDN---ELEILSKIRSTRLVNLVGYSRDNKETVLVVDYMANGTLHDILHCRNE-
|......|.| .| ||.| ..     .|||  ..    .  . .  ..    ||......|   .| | ||. .. .  || .||.||.|.| |.|..  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-P---LSWSIRVQVALQIAKGLRALHSASP--PVIHRDIKSSNVLIDADWNARLADFGLALRGRIEDVIRLSTPP--------AGTMGYLDPGYVS--PG
 |   ||| .|. ... .|.|.. ||...|  |.||.||||.|.| |.. .. ..||||.  |. .   .....          ||  |. | .     |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGH-PASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

HLSTKTDVFSFGILLLEIMSGRNAIDVQYYPPNIVDWALPLIKQGKG---------------------AAI------CDPKSKHPTNAEALNEMAGVAAR
 |..||||.|||| |||. .|. | . .  ..   .  .  |..  |                      ..       |.. . | . .   ||. .| .
QLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHR-MPPCPPNMEKEMCQCACC

CVRLSSSRRPTMAEVVKEL
|.     ||..||.|...|
CGHHRANRRCDMAWVMQQL
Kinase CR4L_a-2.AA TKL-Unique 47-188 33 1.1e-37 130.47 In-house 4-164 (290) Show / Hide 
Range on Protein: 47-188
Range on HMM: 4-164/290
Sequence Identity: 33% (54 aa)

LLGKGSYGWVYKGCLRDGKLVAVKRSS-LARKNSQDDNPLDNELEILSKIR-STRLVNLVGYSR----DNKETVLVVDYMANGTLHDILH---------C
..| |.|| ||||  | |. ||.|. . .. ....    . ||. ...|.. .  .| ..||.     ....  .|..|.  |.|.| ||          
KIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

RNEPLSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDAD-----WNARLADFGLA
.| .|... ||. |..||.|.  ||. .||.||||.||||.|.| .     ||....||||.
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLS
Kinase CR4L_a-2.AA Pkinase 42-240 27 2.7e-36 129.44 Pfam 1-209 (293) Show / Hide 
Range on Protein: 42-240
Range on HMM: 1-209/293
Sequence Identity: 27% (59 aa)

FAREFLLGKGSYGWVYKGCLRDG-KLVAVKRSSLARKNSQDDNPLDN--ELEILSKIRSTRLVNLVGYSRDNKETVLVVDYMANG----TLHDILH-CRN
. ..  .|.||.| |||.. ..  |.||||. .. ...|. |  . .  |..|. ....   | | .. .|...  .| .|. .|     |.|...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EPL--SWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNA----RLADFGLALRGRIEDVIRLSTPPAGTMGYLDPGYVS-PGHLSTKTDV
 ..  |.     ...||..||  .||    .||||.|..|.||| . .     ...|||||   . .   .  | ..|| .|. |  .    . ..| |.
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSFGILLLEIMSGR
.|.|..| | ..||
WSCGCILYEMLCGR
Kinase CR4L_a-2.AA TK 42-310 14 3.8e-32 104.49 In-house 1-486 (486) Show / Hide 
Range on Protein: 42-310
Range on HMM: 1-486/486
Sequence Identity: 14% (74 aa)

FAREFLLGKGSYG---WVYKGCLRDGK--------------------------LVAVKRSSLARKNSQDDNPL---------------DNELEILS--KI
   .  ||.| .|    |||| .|...                           ||||   .   .||..  .                .|.....  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RSTRLVNLVGYSRDN------------KETVLVVDYMANGT----LHDILH-CR----------------------------------------------
.   .|.|.|.. ..            .   .|. ||..|     |.| |. ||                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------NEPLSWSIRVQVALQIAKGLRALHSASP----PVIHRDIKSSNVLIDADWN-----------ARLADFG---
                            ...|.   ..  ..|||.|.. |||        ..|||.   |.|.. . .           ...||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LALRGRIEDVIRLSTPPAGTMG------------------------YLDPGYVS---------PGHLSTKTDVFSFGILLLEIMS-GRNAIDVQY
     || .   .|  . .... ....                        .. |  .           |. .||.||.|||.|. ||.. |.    ..|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQ----EPY

Y--PPN------IVDWA--LPLIKQG-----------------KGAAICDP----KSKHPTNAEALNEMAGVAARCVRLSSSRRPTMAEVVKEL
|   .|        | .  . ....|                 .  . | .    .  | .. ..  |.. .  .| ..  ..|||.......|
YGGMSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CR4L_a-2.AA RIPK 48-242 25 2.7e-31 103.88 In-house 1-227 (290) Show / Hide 
Range on Protein: 48-242
Range on HMM: 1-227/290
Sequence Identity: 25% (57 aa)

LGKGSYGWVYKGCLRDGKLVAVKRS--SLARK---NSQDDNPLDNELEILSKIRSTRLVNLVGYSRDNKE------TVLVVDYMANGTLHDILHCRNE--
.|.|. | |.|   |. . ...|    .. ..   ..|. . .  | ... |.|  . | . |  .. .         .|  ||.|| | . || . .  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

--PLSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNARLADFGLALRGRIE---D--------VIRLSTPPAGTMGYLDPGYVSPGHLS
  |. |. |     .|. |   |||  ||.|||| | .|.|.|.. .. .||||||   .     .         .  | .. ||  |..|    ..  .
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

T------KTDVFSFGILLLEIMSGRNA
       | || ||.|.. |..... .
PIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase CR4L_a-2.AA MLK 42-188 25 2.6e-28 95.37 In-house 1-180 (291) Show / Hide 
Range on Protein: 42-188
Range on HMM: 1-180/291
Sequence Identity: 25% (47 aa)

FAREFLLGKGSYGWVYKGCLRDGKL-----VAVKR-SSLARKNSQD----DNPLDNELEILSKIRSTR----LVNLVGY-SRDNKETVLVVDYMANGTLH
.  .  .|.||.| |.||  | .|.     |||||  . ..  ..|    .  .. | ..|....        . ..|  ...... ..|  |...| |.
IQFHEWIGSGSFGKVWKGRWR-NKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

DILHCRNE-------------PLSWSIRVQVALQIAKGLRALHSASP-PVIHRDIKSSNVLIDA------DWNARLADFGLA
..|| ..                . .  .. |||.|.|.  |||  | |.||||.||.|.|||.      . ... .|||..
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS
Kinase CR4L_a-2.AA Dicty4 42-188 33 6e-28 90.44 In-house 1-161 (277) Show / Hide 
Range on Protein: 42-188
Range on HMM: 1-161/277
Sequence Identity: 33% (54 aa)

FAREFLLGKGSYGWVYKGCLRDGKLVAVKRSSLARKNSQDD--NPLDNELEILSKIRSTRLVNLVGYSR---DNKETVLVV-DYMANGTLHDILHC----
 ..| ..||||.| ||||  | || ||||   .   |.  .  | . .| .|..|||   .. . |..     ...... |  ||  |.|. .||     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--RNEPLSWSIRVQ---VALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNARLADFGLA
   . .|.|. . .    |. .|.|.  ||.  | .||||.||.| |.|..|..  .||||.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLS
Kinase CR4L_a-2.AA LISK 47-188 31 8.6e-28 87.21 In-house 1-152 (296) Show / Hide 
Range on Protein: 47-188
Range on HMM: 1-152/296
Sequence Identity: 31% (49 aa)

LLGKGSYGWVYKGCLR-DGKLVAVKRSSL-----ARKNSQDDNPLDNELEILSKIRSTRLVNLVGYSRD-NKETVLVVDYMANGTLHDILHCRNE---PL
 .|||..| ||||..| .|. .|.|  .       ..  |    .. |.... ..|    |. .| ..  .... .|  |.  |.||..|. ...   ||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKF--MLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL

SWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLID----ADWNARLADFGLA
.|. ||  || ||.|.. |||    .|||| || |.|..     .|.....|||.|
PWPQRVKIALDIACGMSYLHSMN--IIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase CR4L_a-2.AA S_TKc 42-317 21 4.6e-27 97.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 42-317
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

FAREFLLGKGSYGWVYKGCLRD-GKLVAVKRSSLARKNSQDDNPLDNELEILSKIRSTRLVNLVGYSRDNKETVLVVDYMAN--GTLHDILHCRNEP---
.    ..|||..| |||.  .. |..||.|. .         . . .|..||.| .   .|.| .. .| ..  .| .|. .  |.|.|... |. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNARLADFGLALRGRIEDVIRLSTPPAGTMGYLDPGYVSPGHLST-KTDVFSFGIL
  ..      .. ||...|  .||    .||||.| .|.|.|   .  ..||||| .          |   ||  |. |  .   . .. | |. |.|..
FPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLEIMSGRNAIDVQYYPPNIVDWALPLIKQGKGAAICDPKSKHPTNAEALNEMAGVAARCVRLSSSRRPTMAEVVK--ELREISKRI
| | ..|.   .        ..  . .|.                      |.     .| .   ..|||  |. .  ..  .   .
LYEMLCGYPPFP-------QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CR4L_a-2.AA STE 42-188 22 2e-26 90.41 In-house 1-194 (359) Show / Hide 
Range on Protein: 42-188
Range on HMM: 1-194/359
Sequence Identity: 22% (45 aa)

FAREFLLGKGSYGWVYKGCLRD----------------GKLVAVKRSSLARKNS---------------QDDNPLDNELEILSKIR--STRLVNLVGYSR
. .   .|||..| |||.. ..                |...|.|. .| ..|.               .. . . .|..|..| .  .   |.  |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DN-------KETVLVVDYMANGTLHDILH--------------CRNEPLSWSIRVQVALQIAKG-LRALHSASPPVIHRDIKSSNVLIDADWNARLADFG
..        |  ..  ||..|.| ||..              . . ... |.   .. || || |  |||    .||||||..|.|.     . |.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQH-QHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFG

LA
..
VC
Kinase CR4L_a-2.AA LRRK 115-187 36 7.7e-21 70.45 In-house 132-224 (351) Show / Hide 
Range on Protein: 115-187
Range on HMM: 132-224/351
Sequence Identity: 36% (34 aa)

LVVDYMANGTLHDILH--CRNE------PLSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLI---D---------ADWNARLADFGL
.| .|. .|.|.. ||   ...       .||... ..|||||||.. |||..||.|||| || |.|.   .         |. .| .||||.
MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGI
Kinase CR4L_a-2.AA Pkinase_Tyr 42-188 27 8.4e-19 64.31 Pfam 1-158 (270) Show / Hide 
Range on Protein: 42-188
Range on HMM: 1-158/270
Sequence Identity: 27% (45 aa)

FAREFLLGKGSYGWVYKGCLR-----DGKLVAVKRSSLARKNSQD--DNPLDNELEILSKI-RSTRLVNLVGYSR-DNKE--TVLVVDYMANGTLHDILH
      ||.|..| |||| ..     ..  ||||        ...     . .|..|.... .   .|.|.|    . .     .|. ||..| |.| |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

CR---NEPLSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNARLADFGLA
 .   ..||. .  .| ..|||||.  |.|     ||||.   |.|.. .  .. .|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLA
Kinase CR4L_a-2.AA TyrKc 42-310 22 2.2e-18 68.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 42-310
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FAREFLLGKGSYGWVYKGCLRDGKLVAVKRSSLARKNSQDDNPLDNELEILSKI--RSTRLVNLVGYSRDN-------KETVLVVDYMANGTLHDILHCR
   .  || | .| |||| ..    ||||              . .|..|..|.  .   .|.|.|. ..        .   .|. ||..| |.| |. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

NEPLSWSIRVQVALQIAKGLRALHSASPPVIHRDIKSSNVLIDADWNARLADFGLALRGRIE-------DVIRL----STPPAGTMGYLDPGYVSPGHLS
 . |...  .. ..|||.| . |||   ..||||.   |.|....  .. .||||.  .  .       |..|     ..        . |     |  .
RPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TKTDVFSFGILLLEIMSGRNAIDVQYYPP----NIVDWALPLIKQGKGAAICDP----KSKHPTNAEALNEMAGVAARCVRLSSSRRPTMAEVVKEL
||.||.|||... ||..     .  |. .       . .. ..|||.   . .      .      ..  ||  .  .| .   . |||..|.....
TKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CR4L_a-2.AA LISK 221-242 50 8e-06 14.71 In-house 217-238 (296) Show / Hide 
Range on Protein: 221-242
Range on HMM: 217-238/296
Sequence Identity: 50% (11 aa)

STKTDVFSFGILLLEIMSGRNA
... |||||||.|.||  ...|
DESCDVFSFGIVLCEIITRVKA
Kinase CR4L_a-2.AA LRRK 42-96 13 6.1e-05 13.4 In-house 1-105 (351) Show / Hide 
Range on Protein: 42-96
Range on HMM: 1-105/351
Sequence Identity: 13% (14 aa)

FAREFLLGKGSYG-WVYKGCLRD---------------------------GKLVAVKRSSLAR-------KNSQD---------------DNPLDNELEI
. .| ..|.|..|  ||.. .|.                           .. ||.|   . .        || .               |. ... ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LSKIR
... |
FREFR
Kinase CR4L_a-2.AA LRRK 221-240 35 0.000132 12.2 In-house 260-279 (351) Show / Hide 
Range on Protein: 221-240
Range on HMM: 260-279/351
Sequence Identity: 35% (7 aa)

STKTDVFSFGILLLEIMSGR
..|.|..|||..| |.....
TEKVDCYSFGMILWELLTRQ
Kinase CR4L_a-2.AA MLK 221-240 40 0.000155 11.8 In-house 214-233 (291) Show / Hide 
Range on Protein: 221-240
Range on HMM: 214-233/291
Sequence Identity: 40% (8 aa)

STKTDVFSFGILLLEIMSGR
| | ||.|.|..| |.....
SEKCDVWSWGVVLWEMLTRE
Kinase CR4L_a-2.AA Pkinase_Tyr 218-238 52 0.000695 13.78 Pfam 189-209 (270) Show / Hide 
Range on Protein: 218-238
Range on HMM: 189-209/270
Sequence Identity: 52% (11 aa)

GHLSTKTDVFSFGILLLEIMS
|  .||.|| |||.|. ||..
GKFTTKSDVWSFGVLMWEIFT
Kinase CR4L_a-2.AA Dicty4 298-312 23 0.004319 6.35 In-house 261-277 (277) Show / Hide 
Range on Protein: 298-312
Range on HMM: 261-277/277
Sequence Identity: 23% (4 aa)

SRRPTMAEVVKE--LRE
..||...|....  | .
QHRPSFEEIIQRRILEH
Kinase CR4L_a-2.AA Dicty4 223-236 71 0.009709 5.16 In-house 197-210 (277) Show / Hide 
Range on Protein: 223-236
Range on HMM: 197-210/277
Sequence Identity: 71% (10 aa)

KTDVFSFGILLLEI
| ||.||||.| ||
KADVYSFGIVLWEI
Kinase CR4L_a-2.AA TKL-Unique 221-239 57 0.01599 4.93 In-house 206-224 (290) Show / Hide 
Range on Protein: 221-239
Range on HMM: 206-224/290
Sequence Identity: 57% (11 aa)

STKTDVFSFGILLLEIMSG
|.| ||.|||| | || ..
SEKSDVYSFGIVLWEIATR
Kinase CR4L_a-2.AA LRRK 299-312 35 0.016863 4.64 In-house 338-351 (351) Show / Hide 
Range on Protein: 299-312
Range on HMM: 338-351/351
Sequence Identity: 35% (5 aa)

RRPTMAEVVKELRE
.||.. ..|| | .
KRPHFSQIVKRLSQ
Kinase CR4L_a-2.AA MLK 297-310 28 0.029672 3.78 In-house 278-291 (291) Show / Hide 
Range on Protein: 297-310
Range on HMM: 278-291/291
Sequence Identity: 28% (4 aa)

SSRRPTMAEVVKEL
...||.....|..|
PHKRPSFRQIVQHL
Kinase CR4L_a-2.AA STE 221-240 35 0.056199 2.92 In-house 246-265 (359) Show / Hide 
Range on Protein: 221-240
Range on HMM: 246-265/359
Sequence Identity: 35% (7 aa)

STKTDVFSFGILLLEIMSGR
.|| |. |.|....|   |.
DTKCDIWSLGCTIIEMATGK
Kinase CR4L_a-2.AA LISK 288-310 26 0.082513 1.43 In-house 274-296 (296) Show / Hide 
Range on Protein: 288-310
Range on HMM: 274-296/296
Sequence Identity: 26% (6 aa)

VAARCVRLSSSRRPTMAEVVKEL
.. .|...  . ||. .|.|. |
LCFDCCKYDPKNRPSFKEIVQWL
Kinase CR4L_a-2.AA TKL-Unique 297-310 35 0.16497 1.31 In-house 277-290 (290) Show / Hide 
Range on Protein: 297-310
Range on HMM: 277-290/290
Sequence Identity: 35% (5 aa)

SSRRPTMAEVVKEL
.| ||.  |....|
PSQRPSFDEIIHRL
Kinase CR4L_a-2.AA Pkinase_Tyr 291-310 30 0.578035 3.89 Pfam 251-270 (270) Show / Hide 
Range on Protein: 291-310
Range on HMM: 251-270/270
Sequence Identity: 30% (6 aa)

RCVRLSSSRRPTMAEVVKEL
.| .   ..|||..|.. .|
QCWHYDPEDRPTFSEIHEQL