Gene LmjF16.0990 (L.major)

LmjF16.0990

Species: L.major
Alias: LmjF16.0990, LmajK053
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK5

Sequence

Name Sequence Type Origin Length Description Download
LmjF16.0990.AA Protein None 466 None Fasta, JSON
LmjF16.0990.kin_dom Protein Kinase Domain None 432 None Fasta, JSON

Protein domain

Protein domains of LmjF16.0990.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF16.0990.AA CMGC 7-307 21 2.4e-86 283.63 In-house 1-401 (513) Show / Hide 
Range on Protein: 7-307
Range on HMM: 1-401/513
Sequence Identity: 21% (97 aa)

YKHVVKLGEGTYGSVYKGTE--------------IQTGKVVAFKRMV-VTSDDEG---------VPGAAIREICLLKELR-----------------HDN
|. . |.|||||| |||..               ..|...|| |..  .  ..|.         .|  |.||| .||.|.                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVDLFEVLFDPP-----------------KITMIFELCDCDLKRFMES--------RPKRLLDAE----------AEMRPIL------KQIFIGLE--YL
.| |.... ..                  .. ..||..|.||......        ||. | . .             . ..      .||. ||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSRS--VVHRDMKPQNIFVNVRAPDFAALTASPSSRQDHLQPPPFSGVPTAVGGDAQSAAGSGGRPNPFAGVDSVPPREAATAPSNTPNQ--------LI
||.   ..|||.||.|| .| .   . .. .  . .                                                |    .         .
HSHWGNIIHRDLKPENILINHNCELITRM-M--W-K------------------------------------------------S----EDWNPCQKNGR

VKIGDFGLARVEEIP---------------------VKKYSHEVVTLWYRSPDVLMGSALYS---------YPVDIWSMGAIFFEMATS--------KVL
.||.|||||| ....                     .. |.|.|||.|||.| .|.|.  |.         .|.|.|| | ||.|| |         | |
LKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL

FS-----------GLHEDEQVLRMFWLLGSPT---------------RETWPSMLSYPG
|            | .. .|  ..| .||.||                |.||.|...|.
FPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPW
Kinase LmjF16.0990.AA S_TKc 7-438 19 2.7e-73 250.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-438
Range on HMM: 1-231/231
Sequence Identity: 19% (86 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIREICLLKELRHDNVVDLFEVLFDPPKITMIFELCDC---DLKRFMESRPKRLL-
|. . |.|.|..|.|||.... ||..|| |..            ..||| .||. .|.|.| |..|  |  .. |..|.||    ||......|... | 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--DAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVNVRAPDFAALTASPSSRQDHLQPPPFSGVPTAVGGDAQSAAGSGGRPNPFAGVDSVPPREA
    | . | ...||. .|||.||. ..||| ||.||...                                                            
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------------------------------------------------

ATAPSNTPNQLIVKIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSY-PVDIWSMGAIFFEMATSKVLFSGLHEDEQVLRMFWLLGSPTRETW
            .||.||||||.        .. ..|.||..| ||     |.. ..|.|| | |..||.. . .|.      |. .|| ..|       
-----------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------

PSMLSYPGTMERLERASRAAAERPDLRFGSDVCVQQQPPSSQSHSGSRAPDLLTQIAHKRFYHSLKTIQQREESARSSANTYQLPVELWFDRPLFGEYMS
                                                                                                    
----------------------------------------------------------------------------------------------------

ATGFDSCVTAEGVDLLRQCLLYEPNHRITAAAAVR-------HAYL
        . |. |..|.|| ..|..|.||  | .       | ..
--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF16.0990.AA Pkinase 7-287 25 2e-67 235.1 Pfam 1-229 (293) Show / Hide 
Range on Protein: 7-287
Range on HMM: 1-229/293
Sequence Identity: 25% (76 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIR--EICLLKELRHDNVVDLFEVLFDPPKITMIFELCDC-----DLKRFME-SRP
|. . |.|.|..|.|||.... |||.|| |.. . ....... ...|  ||...|.|.|.|.| |...  |...| |..|.|..     ||..... .| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVNVRAPDFAALTASPSSRQDHLQPPPFSGVPTAVGGDAQSAAGSGGRPNPFAGVDSVPPR
....  | | . ...||. ||||.||....|||.||.||... . .. .|                                                  
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA--------------------------------------------------

EAATAPSNTPNQLIVKIGDFGLARVE-EIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGL-----HEDEQVLRM
             .|||.|||||..  . .   ... ..|.||..| |..|.  |...||.||.| |..||.. . .|.|      |.. |....
-------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICR
Kinase LmjF16.0990.AA CDC2 7-140 43 8.3e-63 191.65 In-house 1-137 (301) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-137/301
Sequence Identity: 43% (60 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEG--VPGAAIREICLLKELR-HDNVVDLFEVLFDPPKITMIFELCDCDLKRFME-SRPKRLL
|. . |.|||||| |||. . ||...|| |.  ....|||  ||  |||||..||||. |.|.| |..|..   |. |.|| .|.|||..|. | ||.  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

DAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
  ..  . ...||  |....|.| ..||| |||||...
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID
Kinase LmjF16.0990.AA CDK 213-438 25 8.2e-59 186.72 In-house 152-284 (284) Show / Hide 
Range on Protein: 213-438
Range on HMM: 152-284/284
Sequence Identity: 25% (61 aa)

VKIGDFGLARVEEI------PVKKYSHEVVTLWYRSPDVLMGSALYS--YPVDIWSMGAIFFEMAT---SKVLFSGLHEDEQVLRMFWLLGSPTRETWPS
.||.||||||   |      |...|.|||||||||.|..|.||  ||   |.|.|| | || ||.|    | || |  | .|  . | ..|.|| ..||.
LKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPG

MLSYPGTMERLERASRAAAERPDLRFGSDVCVQQQPPSSQSHSGSRAPDLLTQIAHKRFYHSLKTIQQREESARSSANTYQLPVELWFDRPLFGEYMSAT
. ..|.                                                                                              
VTKLPDY---------------------------------------------------------------------------------------------

GFDSCVTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
           ||| ..| |.|..||.| .|  | |.
-----------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF16.0990.AA CDK5 7-140 47 6e-56 175.03 In-house 1-132 (287) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-132/287
Sequence Identity: 47% (63 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIREICLLKELRHDNVVDLFEVLFDPPKITMIFELCDCDLKRFMESRPKRLLDAEA
|. . |.|||||| |||. . .|. .|| ||    |.||||| .|||||||||||.| |.| |. |.    |.|..|| || |||..|.|.    .|.. 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHI

EMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
 .. .. |   ||.. |.. | |||.||||  .|
-IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLIN
Kinase LmjF16.0990.AA CDK 7-140 38 1.1e-54 173.26 In-house 1-142 (284) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-142/284
Sequence Identity: 38% (59 aa)

YKHVVKLGEGTYGSVYKGTEIQTG-----KVVAFKRMVVTS-----DDEGVPGAAIREICLLKELRHDNVVDLFEVLFDP-----------PKITMIFEL
|. . |.|||||| |||.   |||     ..|| |.  . .     ..||.|  |||||.||||| |.|.| |..|  .             |..|.|| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CDCDLKRFMESRPKRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
.| ||| .|.             . ...|.  ||.|.||. ..|||.||||| .|
MDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN
Kinase LmjF16.0990.AA CDK5 214-302 55 3.1e-47 147.02 In-house 138-227 (287) Show / Hide 
Range on Protein: 214-302
Range on HMM: 138-227/287
Sequence Identity: 55% (50 aa)

KIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMA-TSKVLFSGLHEDEQVLRMFWLLGSPTRETWPSM
| .||||||   |||. ||||||||||| ||||||| .|| ..|.||.| || ||| . . || |  ...|  | | ..|.|. ..|||.
KLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSI
Kinase LmjF16.0990.AA CDC2 213-306 50 2.3e-45 137.06 In-house 142-240 (301) Show / Hide 
Range on Protein: 213-306
Range on HMM: 142-240/301
Sequence Identity: 50% (50 aa)

VKIGDFGLARVEEIPVKKYS--HEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEM---ATSKVLFSGLHEDEQVLRMFWLLGSPTRETWPSMLSYP
.||.||||||   ||...|   |||||||||.| .|.|.  || |||.|| | || ||   .| | ||.|  | .|  ..|  ||.|. .|||.. ..|
IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLP
Kinase LmjF16.0990.AA CDK7 7-140 33 8.6e-39 100.63 In-house 1-136 (288) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-136/288
Sequence Identity: 33% (46 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMV---VTSD-DEGVPGAAIREICLLKELRHDNVVDLFEVLFDPPKITMIFELCDCDLKRFMESRPKRLL
|. . ..|||... |||... |||..|| |.      .|. . |.   ||||| .|.|..||||..|  ..     | ..|.. | ||    .   | ..
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKD--KSII

DAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
   |.   . ...  ||||.|   . |||.|| |  .|
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMN
Kinase LmjF16.0990.AA CDK4 7-140 35 1e-38 130.36 In-house 1-144 (290) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-144/290
Sequence Identity: 35% (52 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDE--GVPGAAIREICLLKELR---HDNVVDLFEV--LFDPPK----ITMIFELCDCDLKRFME
|. |  .||| || ||.   ..||. || |.  . . .|  |.|   |||| ... |    | |.| |..|    |.      |||.||.|| ||. ...
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

SRPKRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
  |.  .  .   . . .|.  |...||| ...||| ||||| |.
KCPPPGM-PPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVT
Kinase LmjF16.0990.AA PFTAIRE 7-139 39 8.3e-36 123.55 In-house 1-130 (287) Show / Hide 
Range on Protein: 7-139
Range on HMM: 1-130/287
Sequence Identity: 39% (52 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIREICLLKELRHDNVVDLFEVLFDPPKITMIFELCDCDLKRFMESRPKRLLDAEA
|. . |||||.|  ||||  . ....|| |      ..||.|  ||||  |||.|.| |.| |  .       |..||  . ||. .|.. |  .     
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGM--HPN

EMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFV
  |  | |   || | | | | |||.||||  .
NVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLI
Kinase LmjF16.0990.AA PFTAIRE 214-307 48 5.6e-35 120.6 In-house 137-231 (287) Show / Hide 
Range on Protein: 214-307
Range on HMM: 137-231/287
Sequence Identity: 48% (46 aa)

KIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGL-HEDEQVLRMFWLLGSPTRETWPSMLSYPG
|  ||||||   .| . ||||||||||| ||||.||  ||  .|.|  | ||.|| . . .| |.    .|  . | .||.|| .|||   . |.
KLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPN
Kinase LmjF16.0990.AA CRK7 7-140 35 7.5e-33 110.49 In-house 1-146 (343) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-146/343
Sequence Identity: 35% (53 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSD---DEGVPGAAIREICLLKELRHDNVVDLFEVLFD--------PPK--ITMIFELCDCDLKRF
|. .   |||||| |||    .||. || |..    .    || |  ||||| .|..| |.|.| | |.  |          |  . |.||  | ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MESRPKRLLD-AEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
.||  | . . .. ... ..||.  |..|.| . . ||| |  || .|
LES--KEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMN
Kinase LmjF16.0990.AA PCTAIRE 214-307 49 9e-33 113.11 In-house 137-236 (291) Show / Hide 
Range on Protein: 214-307
Range on HMM: 137-236/291
Sequence Identity: 49% (49 aa)

KIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGLH------EDEQVLRMFWLLGSPTRETWPSMLSYPG
|  ||||||   .| | |||||||||||.|||||||  || ..|.|  | ||.||.| . || |          .|    | .|| |. .|||   | ..
KLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEE
Kinase LmjF16.0990.AA PCTAIRE 7-140 39 1.9e-32 111.93 In-house 1-131 (291) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-131/291
Sequence Identity: 39% (53 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIREICLLKELRHDNVVDLFEVLFDPPKITMIFELCDCDLKRFMESRPKRLLDAEA
|. . |||||||  |||.    |. .|| |       .|| |  ||||. |||.|.| |.| |  ...     |..||  | |||..|.     .   . 
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

EMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
 .  .| |.  || | | | . |||.||||  .|
KL--FLFQLLRGLAYCHRRKILHRDLKPQNLLIN
Kinase LmjF16.0990.AA PITSLRE 212-300 51 7.7e-32 112.1 In-house 144-232 (295) Show / Hide 
Range on Protein: 212-300
Range on HMM: 144-232/295
Sequence Identity: 51% (46 aa)

IVKIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGLHEDEQVLRMFWLLGSPTRETWP
| ||.||||||    |.|.|.  |||||||.| .| |. .|| |||.|| | || |. | |.|| |  | .|. . | ..| ||   ||
ILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWP
Kinase LmjF16.0990.AA CDK7 212-302 45 7e-29 73.7 In-house 140-230 (288) Show / Hide 
Range on Protein: 212-302
Range on HMM: 140-230/288
Sequence Identity: 45% (41 aa)

IVKIGDFGLARVEEIPVKKYSHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGLHEDEQVLRMFWLLGSPTRETWPSM
..||.||||||    | . |.| ||| |||.|  | |   |   ||.||.| || |       . |  .  |  | |  || || |.|| |
QLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNM
Kinase LmjF16.0990.AA PITSLRE 7-140 30 1.8e-24 86.12 In-house 1-140 (295) Show / Hide 
Range on Protein: 7-140
Range on HMM: 1-140/295
Sequence Identity: 30% (43 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVT--SDDEGVPGAAIREIC-LLKELRHDNVVDLFEVLF--DPPKITMIFELCDCDLKRFMESRP---
.. . . .||||| ||.. . .|. .|| ||. .    . || |  ..|||  .|..|.|.|.| . |..   .  || |..|  . |||  ||      
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

KRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVN
.. .  . |    . |   | |..|.  . ||| |  |.  .
QPFK--PGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYS
Kinase LmjF16.0990.AA CDK4 213-301 44 8.9e-23 74.8 In-house 149-235 (290) Show / Hide 
Range on Protein: 213-301
Range on HMM: 149-235/290
Sequence Identity: 44% (42 aa)

VKIGDFGLARVEEIPVKKYSHE------VVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATSKVLFSGLHEDEQVLRMFWLLGSPTRETWPS
||. ||||||.       || .      |||||||.| ||  |  |  |||.|| | ||.||   . || |  | .|  . | . | |. . ||.
VKLADFGLARI-------YSFQMALTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPR
Kinase LmjF16.0990.AA CRK7 209-300 29 3.6e-18 59.07 In-house 147-278 (343) Show / Hide 
Range on Protein: 209-300
Range on HMM: 147-278/343
Sequence Identity: 29% (39 aa)

NQLIVKIGDFGLARVEEIPV--KKYSHEVVTLWYRSPDVLMGSALY--------------------------------------SYPVDIWSMGAIFFEM
|| .||| ||||||  .     ..|   |.||||| |  | |   |                                         .|.|| | |. | 
NQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGEL

ATSKVLFSGLHEDEQVLRMFWLLGSPTRETWP
.| | .| |  | .|    . . |||. . ||
FTKKPIFQGNNEMAQLEKIYKICGSPNPNNWP
Kinase LmjF16.0990.AA CDC2 403-438 47 5.1e-12 32.69 In-house 267-301 (301) Show / Hide 
Range on Protein: 403-438
Range on HMM: 267-301/301
Sequence Identity: 47% (17 aa)

FDSCVTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
. ||.. ||.|||.| | |.|..||.| .| .| |.
Q-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase LmjF16.0990.AA TyrKc 7-436 14 4.7e-11 -43.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-436
Range on HMM: 1-280/280
Sequence Identity: 14% (69 aa)

YKHVVKLGEGTYGSVYKGTEIQTGKVVAFKRMVVTSDDEGVPGAAIREICLLKEL--RHDNVVDLFEVLFDP-------PKITMIFELCDC-DLKRFMES
 .   ||||| .| ||||| .     || | .   .       . .||. ....|  .|.|.| |. |  ..       . . ...|...  ||| .  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RPKRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRDMKPQNIFVNVRAPDFAALTASPSSRQDHLQPPPFSGVPTAVGGDAQSAAGSGGRPNPFAGVDSVP
. ..     ...  .  ||  | |||||. ..|||    |. |. .                                                      
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------------------------------------------

PREAATAPSNTPNQLIVKIGDFGLARVE----------EIPVKKY---SHEVVTLWYRSPDVLMGSALYSYPVDIWSMGAIFFEMATS-KVLFSGL----
               .|||.||||.|            .  .||    .. .. .   .| ..     ..   |.|| |   .|. |  .   .|     
---------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQM

HEDEQVLRMFWLLGSPTRETWPSM---LSYPGTMERLERASRAAAERPDLRFGSDVCVQQQPPSSQSHSGSRAPDLLTQIAHKRFYHSLKTIQQREESAR
 ....|..   .. .  |   |     .|                                                                       
MSNQEVIE---YVKQGYRMPQPPNDYPMS-----------------------------------------------------------------------

SSANTYQLPVELWFDRPLFGEYMSATGFDSCVTAEGVDLLRQCLLYEPNHRITAAAAVRHA
                           |  | ..|  .. .||  ..|. | | .. ..  
---------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF16.0990.AA CMGC 403-438 38 4.7e-11 31.63 In-house 478-513 (513) Show / Hide 
Range on Protein: 403-438
Range on HMM: 478-513/513
Sequence Identity: 38% (14 aa)

FDSCVTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
...| . ...||| ..| |.|. ||||. | .| |.
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF16.0990.AA CDK5 409-438 46 6.8e-10 26.94 In-house 258-287 (287) Show / Hide 
Range on Protein: 409-438
Range on HMM: 258-287/287
Sequence Identity: 46% (14 aa)

AEGVDLLRQCLLYEPNHRITAAAAVRHAYL
..| ||| . | ..||.||.|.|| .|.| 
EKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase LmjF16.0990.AA CDK4 411-438 35 1.1e-09 29.16 In-house 263-290 (290) Show / Hide 
Range on Protein: 411-438
Range on HMM: 263-290/290
Sequence Identity: 35% (10 aa)

GVDLLRQCLLYEPNHRITAAAAVRHAYL
| ||| ..| |.. .|..| ..  | |.
GDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase LmjF16.0990.AA Pkinase_Tyr 7-131 30 9.1e-09 30.31 Pfam 1-136 (270) Show / Hide 
Range on Protein: 7-131
Range on HMM: 1-136/270
Sequence Identity: 30% (42 aa)

YKHVVKLGEGTYGSVYKGTEI----QTGKVVAFKRMVVTSDDEG-VPGAAIREICLLKEL-RHDNVVDLFEVLF--DPP-KITMIFELCDC-DLKRFMES
 .   ||||| .|.|||||      .|.  || | .  ....|     . .||. ..|.| .|.|.| |  |    . | .| ...|.. . ||. .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R--PKRLLDAEAEMRPILKQIFIGLEYLHSRSVVHRD
.  .|. |. .  .  .  ||  |.|||.|.  .|||
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRD
Kinase LmjF16.0990.AA PCTAIRE 410-438 37 5.7e-08 24.16 In-house 263-291 (291) Show / Hide 
Range on Protein: 410-438
Range on HMM: 263-291/291
Sequence Identity: 37% (11 aa)

EGVDLLRQCLLYEPNHRITAAAAVRHAYL
.. ||| . |.||.  |. |..|..| | 
QCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase LmjF16.0990.AA PFTAIRE 409-438 33 1e-06 19.59 In-house 258-287 (287) Show / Hide 
Range on Protein: 409-438
Range on HMM: 258-287/287
Sequence Identity: 33% (10 aa)

AEGVDLLRQCLLYEPNHRITAAAAVRHAYL
... ||. . | .||  |. |..|. | |.
PHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase LmjF16.0990.AA PITSLRE 407-438 43 7e-06 17.52 In-house 264-295 (295) Show / Hide 
Range on Protein: 407-438
Range on HMM: 264-295/295
Sequence Identity: 43% (14 aa)

VTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
..  | ||| | | | |  |||| .|  | . 
ISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase LmjF16.0990.AA CRK7 405-438 29 3.2e-05 13.71 In-house 310-343 (343) Show / Hide 
Range on Protein: 405-438
Range on HMM: 310-343/343
Sequence Identity: 29% (10 aa)

SCVTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
.  ..| .||| . | . |  |.||  . .| ..
VFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase LmjF16.0990.AA CDK7 412-438 22 0.000113 7.9 In-house 262-288 (288) Show / Hide 
Range on Protein: 412-438
Range on HMM: 262-288/288
Sequence Identity: 22% (6 aa)

VDLLRQCLLYEPNHRITAAAAVRHAYL
.||.   .. .|  |.|.. .  . | 
LDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase LmjF16.0990.AA Pkinase 407-438 28 0.004988 11.79 Pfam 262-293 (293) Show / Hide 
Range on Protein: 407-438
Range on HMM: 262-293/293
Sequence Identity: 28% (9 aa)

VTAEGVDLLRQCLLYEPNHRITAAAAVRHAYL
.. |. |... || . |. |.||. .. | ..
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF16.0990.AA Pkinase_Tyr 209-222 64 0.029826 8.25 Pfam 146-159 (270) Show / Hide 
Range on Protein: 209-222
Range on HMM: 146-159/270
Sequence Identity: 64% (9 aa)

NQLIVKIGDFGLAR
....|||.||||||
ENNVVKICDFGLAR