Gene LmjF18.0270 (L.major)

LmjF18.0270

Species: L.major
Alias: LmjF18.0270, LmajK075
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
LmjF18.0270.AA Protein None 355 None Fasta, JSON
LmjF18.0270.kin_dom Protein Kinase Domain None 294 None Fasta, JSON

Protein domain

Protein domains of LmjF18.0270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF18.0270.AA GSK 20-313 41 1.1e-151 466.94 In-house 1-328 (328) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-328/328
Sequence Identity: 41% (139 aa)

FQVERMAGQGTFGTVQLGKEK----STGMS----VAIKKVIQDPRFR-NRELQIMQDLAVLHHPNIVQLQSYFYTLGE-RDRRDIYLN-VVMEYVPDTLH
..  .  |.|.||.|  .. .     |.      |||||| ||.|.. |||||||..|. |.|||||.|. .||. .| .|  . |.|  ||||.| ||.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

RCCRNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSP--SEPNVAYICSRYYRAPELIFGNQHYTT
.  | | . .   | |.||.. .|. |... ||  | ..||||||| |.||.. .|.||.|||||||.| |  .|||..||||||||||||||| ..||.
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLH--SHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTC

AVDIWSVGCIFAEMMLGEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLY-----NSKGIPWSN-------------------VFSD-HSLK
..|.||.||..|||..|.|.| ||.|  || ||...|| |..| ... |||.. ..       . |..||.                    .|   |.  
QIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDM

DAKEAYDLLSALLQYLPEERMKPYEALCHPYF
.  ...||.|..|.| |..| .|.||..||.|
Q--DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase LmjF18.0270.AA CMGC 20-313 21 1.7e-103 341.06 In-house 1-513 (513) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-513/513
Sequence Identity: 21% (111 aa)

FQVERMAGQGTFGTVQLGKEKSTGMS--------------VAIKKVIQDPRFRN----------------RELQIMQDLAV--------------LHHPN
... .  |.||.|.|  .. | |.                |||||. ... . .                ||..|.. |                 ||.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVQLQSYFYTLGERDRRDI----------YLNVVMEYVPDTLHRCCRNYYR-----RQVAPPPIL------------IKVFL------FQLIRSIG--CL
||.|. .||. ...   .           .|. |.||.. .|..  .|. .     |..  ..              || |.      .|..|..    .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HLPSVNVCHRDIKPHNVLVNEA-------------------DGTLKLCDFGSAKKLSP----------------------SEPNVAYICSRYYRAPELIF
|    |..|||.|| |.|.|.                    .|.||.||||.|....|                      ..|.  |...|.|||||...
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GN---------QHYTTAVDIWSVGCIFAEMMLG--------EPIFRGDNS-----------AGQLHEIVRVLGCPS---------------REVLRKLNP
|          .||||..|.||||||||||..|        .|.| |...             ||..|..||| |.                |   . ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

SHTDVD---------------------------LYNSKGIPWSNVFSDHSL-------------------------------KDAKEAYDLLSALLQYLP
  .                              . . ...||.|.| .|.                                .. ..| |||. .||| |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

EERMKPYEALCHPYF
..|... .|| ||||
DKRITAEQALQHPYF
Kinase LmjF18.0270.AA S_TKc 20-313 27 3.4e-78 267.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKVIQDPRFRNRELQIMQDLAVLHHPNIVQLQSYFYTLGERDRRDIYLNVVMEYVPD---TLHRCCRNYYR
... |  |.|.||.| ....|.||  ||||..    .   ||.||..     ||||||.|  .|..         .| .||||..    .|..  ... |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK----HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKKRGR

--RQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSPSEPNVAYICSRYYRAPELIFGNQHYTT-AVDIWSV
  ...  |.  .. .. |... .  .|  | ...|||.|| |.|..|   ..|.||||.|..|        .. ...|.|||..    .|.. ..|.||.
HGLRFPFPE-HARFYMYQICCALEYCH--SHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GCIFAEMMLGEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLYNSKGIPWSNVFSDHSLKDAKEAYDLLSALLQYLPEERMKPYEALC----
|||..||. |.| |.      |.... ...|                                       .|| |... .||. ||.|.   |||     
GCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

---HPYF
   ||.|
IKCHPWF
Kinase LmjF18.0270.AA CDK 20-313 29 1.7e-72 231.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-284/284
Sequence Identity: 29% (99 aa)

FQVERMAGQGTFGTVQLGKEKSTG-----MSVAIKKVIQDP--------RFRN---RELQIMQDLAVLHHPNIVQLQSYFYTL-----GERDR--RDIYL
..     |.||.|.|  .. | ||       ||.||.. .          |     ||  ....|    |||||.|   ..|      . .|.  . .|.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL----HPNIVKLHDVCHTKNMDRNN-KDKHENKLYM

NVVMEYVPDTLHRCCRNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEAD----GTLKLCDFGSAKKLS-------PSEPNVA
  |.||..  |    .             || ...||.| .  .|  | .. |||.|| | |.|.      |.||. ||| |.. .       |. .   
--VFEYMDHDLKKYMD-------------IKCYMWQLLRGLHYCH--SNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTH

YICSRYYRAPELIFGNQHYT--TAVDIWSVGCIFAEMML---GEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLYNSKGIPWSNVFSDHSL
 .  . |||||| .| .||.  |..|.||||||||||..   ..|.| ||.   ||. | |..|.|. ..     |. |.  .|                
EVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNW----PGVTKLPDY----------------

KDAKEAYDLLSALLQYLPEERMKPYEALCHPYF
       |||. .|.| |. |..  .|| ||||
-------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF18.0270.AA Pkinase 20-313 27 8.9e-68 236.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKVIQDPRFRNR--------ELQIMQDLAVLHHPNIVQLQSYFYTLGERDRRDIYLNVVMEYVPDTLHRCC
....|  |.|.||.| ....|.||  ||.|..  . .  .         |.|||. |    |||||.|  .|..     ...||  .||||.. .|. . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFED-----KDHIY--MVMEYCEGGLY-VM

RNY----YRRQVAP--PPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTL----KLCDFGSAKK--LSPSEPNVAYICSRYYRAPELIF
  .     .|. .   ..  .| .. |..| .  .|    ...|||.|| |.|..  .|..    |.||||.||.  . ... .  . ....|.|||.| 
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS--MGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR

GNQHYTTAVDIWSVGCIFAEMMLGEPIFRGD----NSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLYNSKGIPWSNVFSDHSLKDAKEAYDLLSALLQ
|.|.|...||.||.|||..||..|.|.|.|.    | . |.. |.|..|.| ..   ....  ..  ..  .       ..    .  .|. |... .|.
GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLC

YLPEERMKPYEALCHPYF
. |..|  . ..|.||.|
KDPKKRPTAEQILQHPWF
Kinase LmjF18.0270.AA CDC2 20-313 30 5e-59 179.82 In-house 1-301 (301) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-301/301
Sequence Identity: 30% (96 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKVIQDPRFRN--------RELQIMQDLAVLHHPNIVQLQSYFYTLGERDRRDIYLNVVMEYVPDTLHRCC
.|  .. | ||.| |  .|.. |.  ||.||.  .             ||. ....|    |||||.|.  ..       . .|.  | ||.   | .  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELK--DHPNIVKLHDVIHQ------NKLYM--VFEYLDMDLKKYM

RNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLS-PSEPNV--AYICSRYYRAPELIFGNQHYTTAV
...   .   ||.|.| ...|... .  .|  .  . |||.|| | |.. ..|..|. ||| |.  . |. .      .  . |||||. .| ..|.|.|
DMSIPKNKHMPPQLVKSYMYQILQGVHFCH--QRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPV

DIWSVGCIFAEM---MLGEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLYNSKGIPWSNVFSDHSLKD----------AKEAYDLLSALLQ
|.||.|||||||   .  .|.| ||    ||  | |.|| |. . .    |. |.   |...   |      . ...           .|. |||. .||
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTW----PGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQ

YLPEERMKPYEALCHPYF
| |. | .  ||| ||||
YDPQKRISAKEALQHPYF
Kinase LmjF18.0270.AA MAPK 20-313 32 1.3e-57 197.77 In-house 1-328 (328) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-328/328
Sequence Identity: 32% (109 aa)

FQVERMAGQGTFGTVQLGKEKSTGMS------VAIKKV---IQDPRFRN---RELQIMQDLAVL-HHPNIVQLQSYFYTLG---ERDR---RDIYLNVVM
.|  .  ||| .|.|   . |.|..       |||||.    |.| .     ||. ...    . ||.||. |.  |.  .   ....   .|||.  ||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLR---HFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYI--VM

EYVPDTLHRCCRNYYRRQVAPPPILIKVFLFQLIRSIG--CLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSPSEPNVA-------------
|.    ||.  .           . |. |..|..|  |    .. | || |||.|| |.|||| ...||.|||| | .. |..                 
ELMETDLHQIIKSQQ----PLSDDHIQYFMYQILR--GLKLKYIHSANVIHRDLKPSNILVNE-NCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHM

--YICSRYYRAPELIFG--NQHYTTAVDIWSVGCIFAEMML-GEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLN-PSHTDVDLYN------SKGIPWSN
  |.  |.|||||....   .|||.|||.||||||||||.  . |.|.|...  |.  |. ||| ||.|.....  ..|    . .       ...||..
TEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEK

VFSDHSLKDAKEAYDLLSALLQYLPEERMKPYEALCHPYF
.|.... .   .| |||. .|.  |..|    ||| ||||
MFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF18.0270.AA CDK7 149-313 38 2.2e-52 137.6 In-house 125-288 (288) Show / Hide 
Range on Protein: 149-313
Range on HMM: 125-288/288
Sequence Identity: 38% (65 aa)

HRDIKPHNVLVNEADGTLKLCDFGSAKKL-SPSEPNVAYICSRYYRAPELIFGNQHYTTAVDIWSVGCIFAEMMLGEPIFRGDNSAGQLHEIVRVLGCPS
|||.|| | |.|| .| ||. ||| |.   || .     .  |.|||||| ||  ||.|.||.||||||||| ||  |.. ||.   ||  | . ||.|.
HRDLKPNNLLMNE-NGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPT

REVLRKLNPSHTDVDLYNSKG---IPWSNVFSDHSLKDAKEAYDLLSALLQYLPEERMKPYEALCHPYF
 |    .   .. . . .  |   .|  ..|.  |     .. ||.. ..   | .|..  ..| .|||
EEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAAS----DDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase LmjF18.0270.AA ERK7 20-313 31 1.1e-48 164.54 In-house 1-292 (292) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-292/292
Sequence Identity: 31% (96 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKVIQDPRFRN--------RELQIMQDLAVLHHPNIVQLQSYFYTLGERDRRDIYLNVVMEYVPDTLHRCC
.....  |.| .| |     | |.  ||.||.     |||        ||  ..|..   .||||..|   .        |||||  | |.    ||   
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFD--AFRNQTDAQRTFREIMFLQEFH--CHPNIIRLINVIRA---DNDRDIYL--VFEFMETDLH---

RNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSPSE------PNVA-YICSRYYRAPELIFGNQHY
 .  |.      |  .. ..||.| |  .|  | || |||.|| |.|.. .. ..|.|||| |  ..  |      | .  |.  | |||||   | ..|
-AVIRKGNILKDIHKQYIMYQLLRAIKYMH--SGNVIHRDLKPSNILLD-SECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRY

TTAVDIWSVGCIFAEMMLGEPIFRGDNSAGQLHEIVRVLGCPSREVLRKLNPSHTDVDLYNSKGIPWSNVFSDHSLKDAKEAYDLLSALLQYLPEERMKP
| .|| ||.||| .||. | |.| |     |.  |..... |..| .  ....   . | . .       ...   .  ..| ||| .||.. |..|.  
TKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTA

YEALCHPYF
 .|| ||| 
EQALQHPYV
Kinase LmjF18.0270.AA ERK 126-313 35 2.5e-47 163.57 In-house 110-307 (307) Show / Hide 
Range on Protein: 126-313
Range on HMM: 110-307/307
Sequence Identity: 35% (72 aa)

IKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSPSEPNV---------AYICSRYYRAPELIFGNQHYTTAVDIWSVGCI
.. |. |...  | ... | || |||.|| |.|||. ...|| |||| | .. .|  .           |. .|.|||||..  .| ||.|.||||.|||
CQYFMYQILC--GLKYIHSANVIHRDLKPSNILVNS-NCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCI

FAEMMLGEPIFRGDNSAGQLHEIVRVLGCP-SREVLRKL-NPSHTDVDLYNSK----GIPWSNVFSDHSLKDAKEAYDLLSALLQYLPEERMKPYEALCH
||||. . |.|.| .. .|. .|  ..| | | | |..  ..   .   . ..    ..||.|.|.....   ..| |||. .|.  |..|    |.| |
FAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCN--PQAIDLLEKMLVFDPDKRITVEECLEH

PYF
|||
PYF
Kinase LmjF18.0270.AA DYRK 125-253 38 5.5e-34 119.22 In-house 104-230 (320) Show / Hide 
Range on Protein: 125-253
Range on HMM: 104-230/320
Sequence Identity: 38% (51 aa)

LIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNE--ADGTLKLCDFGSAKKLSPSEPNVAYICSRYYRAPELIFGNQHYTTAVDIWSVGCIFAEMML
|...|..|.  ..  || .  |  | |.|| |.....     |.|..||||.   .       || ||.||||| | | . | .|.|.||.||| ||. .
LVRKFAQQILTCLKFLHKNE-NIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ--RIYTYIQSRFYRAPEVILGCP-YCYAIDMWSLGCILAELFT

GEPIFRGDNSAGQLHEIVRVLGCPSREVLRK
|.|.| |.|   ||  |. ||| |......|
GWPLFPGENEYDQLACIMEVLGMPPKWMIDK
Kinase LmjF18.0270.AA MAPK-Unclassified 186-313 27 1.4e-30 107.49 In-house 408-575 (575) Show / Hide 
Range on Protein: 186-313
Range on HMM: 408-575/575
Sequence Identity: 27% (47 aa)

YICSRYYRAPELIFGNQHYTTAVDIWSVGCIFAEMMLG-----------EPIFRGDN--------------------SAGQLHEIVRVLGCPSREVLRKL
|.  |.|||||... .. |.|.|||||.||||||||.             |.| |..                    . .|.  |. .|| |  |...  
YVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDCNFI

NPSHTDVDLYNSKGIPWSNVFSDHSLKDAK----------EAYDLLSALLQYLPEERMKPYEALCHPYF
  . . ... .| .   .  |.|     |           |. |... .||. |  |    .|| ||||
TCDSA-RKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase LmjF18.0270.AA MAPK-Unclassified 20-172 32 3.1e-18 62.13 In-house 1-154 (575) Show / Hide 
Range on Protein: 20-172
Range on HMM: 1-154/575
Sequence Identity: 32% (54 aa)

FQVERMAGQGTFGTVQLGKEKST-GMSVAIKKVI------QDPRFRNRELQIMQDLAVLHHPNIVQLQSYFYTLGERD--RRDIYLNVVMEYVPD---TL
  ..   |.| .| |   ..|.. .  ||||||       .| .   ||. |   |  | ||||.|.|  ||. .       |||.  ||.| .     |
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRI---LRYLNHPNIIQIQDIFYNKELHNQEFDDIYI--VMDYMQTSLFDL

HRCCRNYYRRQVAPPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFG
|     .. .|     ..|. |. |. | .  ||  | .. ||| || |.|.|. |.... ||||
HQI---IKSNQDHWCHQHIQYFFYQILRGLKYLH--SACIIHRDLKPSNLLINQ-DCSVRICDFG
Kinase LmjF18.0270.AA CDK7 20-51 37 3.9e-10 22.75 In-house 1-32 (288) Show / Hide 
Range on Protein: 20-51
Range on HMM: 1-32/288
Sequence Identity: 37% (12 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKV
.. ..  | |.|.|| .. ...||  |||||.
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKI
Kinase LmjF18.0270.AA TyrKc 20-313 24 4.8e-10 -60.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-280/280
Sequence Identity: 24% (79 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIKKVIQDPRFRN---RELQIMQDLAVL--HHPNIVQLQSYFYTLGERDRRDI----YLNVVMEYVPDTLHRC
 . ... | | ||.| .|. |   . ||.|..  |   |    ||..||     |  ||||||.|  .  . |..          | .||||.|   | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIM---CKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMP---HGD

CRNYYRRQVA-PPPILIKVFLFQLIRSIGCLHLPSVNVCHRDIKPHNVLVNEADGTLKLCDFGSAKKLSPS----EPNVAYI-----CSR-----YYRAP
...| |.     ..     | .|   . |. .| | |. |||.   |.||.|   | | .||| ....       |    |      ...        ||
LKDYLRKHRPKLCMKDLLSFCWQI--ACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ELIFGNQHYTTAVDIWSVGCIFAEMM-LGEPIFRGD----NSAGQLHEIVRVLGCPSREVL----RKLNPSHTDVDLYNSKGIPWSNVFSDHSLKDAKEA
| |     .||. |.|| |    |.. .|..   |.     |. ...| |.  . . .                              |        .| 
ECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------F----VCCPDEM

YDLLSALLQYLPEERMKPYEALCHPYF
|.. .   .. ||.|    |   | .|
YQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF18.0270.AA DYRK 288-313 42 3.9e-07 22.99 In-house 295-320 (320) Show / Hide 
Range on Protein: 288-313
Range on HMM: 295-320/320
Sequence Identity: 42% (11 aa)

DLLSALLQYLPEERMKPYEALCHPYF
|..  .||. |..|..|..|| || |
DFIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF18.0270.AA Pkinase_Tyr 20-79 31 5e-06 21.06 Pfam 1-69 (270) Show / Hide 
Range on Protein: 20-79
Range on HMM: 1-69/270
Sequence Identity: 31% (23 aa)

FQVERMAGQGTFGTVQLGKEK----STGMSVAIKKV--IQDPR------FRNRELQIMQDLAVLHHPNIVQL
 .  .. |.| ||.| .|. |    .|.. ||.|..    ...      | . |..||  |   ||||||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLG--HHPNIVRL
Kinase LmjF18.0270.AA DYRK 20-49 33 0.000252 12.39 In-house 1-30 (320) Show / Hide 
Range on Protein: 20-49
Range on HMM: 1-30/320
Sequence Identity: 33% (10 aa)

FQVERMAGQGTFGTVQLGKEKSTGMSVAIK
...  . |.|.|| |  .. . |.  ||||
YEILEYIGKGSFGQVVKCWDHKTNEMVAIK
Kinase LmjF18.0270.AA ERK 20-51 35 0.004926 7.37 In-house 1-37 (307) Show / Hide 
Range on Protein: 20-51
Range on HMM: 1-37/307
Sequence Identity: 35% (13 aa)

FQVERMAGQGTFGTVQLGKEKS-----TGMSVAIKKV
.|     |.|..|.|   . |.     ||  |||||.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKI
Kinase LmjF18.0270.AA Pkinase_Tyr 156-172 52 0.640093 3.74 Pfam 141-156 (270) Show / Hide 
Range on Protein: 156-172
Range on HMM: 141-156/270
Sequence Identity: 52% (9 aa)

NVLVNEADGTLKLCDFG
|.||.| ... | ||||
NCLVTE-NNVVKICDFG
Kinase LmjF18.0270.AA Pkinase_Tyr 194-212 47 1.370659 2.62 Pfam 182-199 (270) Show / Hide 
Range on Protein: 194-212
Range on HMM: 182-199/270
Sequence Identity: 47% (9 aa)

APELIFGNQHYTTAVDIWS
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APECINYGK-FTTKSDVWS