Gene LmjF13.1640 (L.major)

LmjF13.1640

Species: L.major
Alias: LmajK079, LmjF13.1640
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF13.1640.AA Protein None 605 None Fasta, JSON
LmjF13.1640.kin_dom Protein Kinase Domain None 437 None Fasta, JSON

Protein domain

Protein domains of LmjF13.1640.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF13.1640.AA MAPK 146-392 35 1.2e-89 304.1 In-house 32-250 (328) Show / Hide 
Range on Protein: 146-392
Range on HMM: 32-250/328
Sequence Identity: 35% (94 aa)

FVAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGA--SSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKV--
.|||||. ..|..... .|..|||||||.. .|.||..| .. .| . .    .|   |.|||.|..||.||| ....| |.   |  ... ||. .   
KVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEM-Q-DDQNSLEEFNDIYIVMELMETDLHQIIKSQQPLSDDHIQYFMYQILRGLK

LVYVHSSGVIHRDLKPGNILLNGNCDMKLCDFGLSRGGVPA-------------WPHERTLTAVATAAESSAKELEDWGLFCWSSSAARGASSAPHAAKQ
| | || .||||||||.|||.| ||| |.|||||.|.  |                                                            
LKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQ---------------------------------------------

PPLYSLTDYVVTRYYRAPELLIM---GRYNHAIDMWSAGCILAEMVL-RRPLFTGANYLSQLALILET
   . .|.||.||.|||||..      .|. |.||||.|||.|||.  |.||| | .|. |. ||.|.
--KMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEV
Kinase LmjF13.1640.AA CMGC 52-392 19 5.1e-85 279.18 In-house 1-369 (513) Show / Hide 
Range on Protein: 52-392
Range on HMM: 1-369/513
Sequence Identity: 19% (97 aa)

FEVLNGIGYGAYGVVCAAVDLR-----LVASSVYYNEAMRTIEEEGRIVTRQRRGHDAPVYFRTRAVLDEAGRGGPVRVPHLYSEPFKRRTLARGEVSPF
.|... || |.||||. ..| |     .                                                                        
YEIIKKIGEGTYGVVYKCRDKRTNQKKD-----------------------------------------------------------------------N

-----------VAIKKVTKVFDDLVDGR----------RILREIKLLRYLQ----------------GHPNIVRLMEVGRPPA--PTGASSSAA----FD
           |||||. ..| .  ...          |.|||||.|..|.                 |.|||.| .. ...   .......      |.
GQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFN

DIYLVTDLMDTDLGALLRSSQE----------------------------IAMDQLRFIAYQLMKVLV--YVHSSG--VIHRDLKPGNILLNGNCDM---
..|||...||.||  .... |                             . . . | ..||. . |   | || .  .||||||| |||.| ||.    
HLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITR

-----------------KLCDFGLSR-GGVP----------------AWPHERTLTAVATAAESSAKELEDWGLFCWSSSAARGASSAPHAAKQPPLYSL
                 |.|||||.|  ...                .                                            . .|.  .
MMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNK-------------------------------------------DD-KPNRPY

TDYVVTRYYRAPELLIMGR----------YNHAIDMWSAGCILAEMVLR--------RPLFT-----------GANYLSQLALILET
|.|||||.|||||.|.  .          |. .|||||.|||.|||...        .|||            |.... ||..| ..
THYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKV
Kinase LmjF13.1640.AA S_TKc 52-488 20 8.3e-69 235.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-488
Range on HMM: 1-231/231
Sequence Identity: 20% (91 aa)

FEVLNGIGYGAYGVVCAAVDLRLVASSVYYNEAMRTIEEEGRIVTRQRRGHDAPVYFRTRAVLDEAGRGGPVRVPHLYSEPFKRRTLARGEVSPFVAIKK
.|.|. || ||.|.|. ... .          |.  |                                                               
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------------------------------------------------------------

VTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDT---DLGALLRSSQE------IAMDQLRFIAYQLMKVL
           ..|.|||..|.   .|||||.| .| .             |..|.|....|.   ||  .... .       .   . ||..||. . |
-----------EHIRREIQILKK--HHPNIVKLYDVFQD------------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCAL

VYVHSSGVIHRDLKPGNILLNGNCDMKLCDFGLSRGGVPAWPHERTLTAVATAAESSAKELEDWGLFCWSSSAARGASSAPHAAKQPPLYSLTDYVVTRY
 | || |.||||||| ||||.     |.|||||.|                                                         | ...|..
EYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------------------TTFCGTPW

YRAPELLIMGRYNH-AIDMWSAGCILAEMVLRRPLFTGANYLSQLALILETPGLRGVPQTPEEAAALFEGGEEGKHFINDILFHKTARRRDPLTLSDQVH
|.|||.|    |.. ..|.|| ||||.||. ..|.|       |......  |                                               
YMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----------------------------------------------

SQVLFHSTLFGFKVDVPISLGILIAKLLSFDPRKRPTALEALR-------DPFF
                . ..  .| |.| .||.||||| |||.       .|.|
----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF13.1640.AA ERK 146-278 48 3.1e-53 183.19 In-house 31-157 (307) Show / Hide 
Range on Protein: 146-278
Range on HMM: 31-157/307
Sequence Identity: 48% (64 aa)

FVAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYV
.|||||....||....  |.||||||||.. ||.||. |  . .|  |..      ..|||.|..||.|||    .|.||.  |   .  ||.   | |.
KVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQ------YNDIYCVEELMETDLHQIINSQQELSDDHCQYFMYQILCGLKYI

HSSGVIHRDLKPGNILLNGNCDMKLCDFGLSRG
||..||||||||.|||.| ||| | |||||.|.
HSANVIHRDLKPSNILVNSNCDLKICDFGLARC
Kinase LmjF13.1640.AA MAPK-Unclassified 147-277 42 2.1e-49 170.48 In-house 28-157 (575) Show / Hide 
Range on Protein: 147-277
Range on HMM: 28-157/575
Sequence Identity: 42% (57 aa)

VAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDT---DLGALLRSSQ-EIAMDQLRFIAYQLMKVL
||||||...| . .| .|.|||| .||||  ||||... .. ..  . .      |||||.|.|.| |   ||  ...| |    . . . . ||... |
VAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQDIFYNKELHN----QEFDDIYIVMDYMQTSLFDLHQIIKSNQDHWCHQHIQYFFYQILRGL

VYVHSSGVIHRDLKPGNILLNGNCDMKLCDFGLSR
 | || ..||||||| |.|.|..|  . ||||.||
KYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase LmjF13.1640.AA p38 146-277 39 2.2e-44 149.47 In-house 29-154 (289) Show / Hide 
Range on Protein: 146-277
Range on HMM: 29-154/289
Sequence Identity: 39% (52 aa)

FVAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYV
.|||||  . | . .. .|. ||..||. .. | |.. |..|  |     |.|   | |.|.|| .|..||  ... .| .  |. .|. ||... | |.
YVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTP----PAHSMNDFQDVYMVTHFMGADLNNIMK-CQRLSDDHIQFLVYQILRGLKYI

HSSGVIHRDLKPGNILLNGNCDMKLCDFGLSR
|| |.|||||||.|| .|..|...  ||||.|
HSAGIIHRDLKPSNIAVNEDCELRILDFGLAR
Kinase LmjF13.1640.AA ERK7 147-277 44 2.1e-38 128.78 In-house 27-148 (292) Show / Hide 
Range on Protein: 147-277
Range on HMM: 27-148/292
Sequence Identity: 44% (59 aa)

VAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFD-DIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYV
||.||.   | . .|  |  ||| .|. ...||||.||..| |          |  | ||||| . |.||| |  |  . .     ..| |||.. . |.
VALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIR----------ADNDRDIYLVFEFMETDLHAVIRKGNILKDIHKQYIMYQLLRAIKYM

HSSGVIHRDLKPGNILLNGNCDMKLCDFGLSR
||  |||||||| ||||. .| .|.||||| |
HSGNVIHRDLKPSNILLDSECMVKVCDFGLAR
Kinase LmjF13.1640.AA nmo 147-277 40 6.8e-38 113.68 In-house 27-150 (292) Show / Hide 
Range on Protein: 147-277
Range on HMM: 27-150/292
Sequence Identity: 40% (53 aa)

VAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYVH
||.||. .|| .||  .|. ||.|.| . . | |.. .... .|| .        |..|| ||.||  ||  .. | |... | ..   ||... | |.|
VALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDNVLSALDILQPPHK------DFFQEIYVVTELMQSDLHKIIVSPQHLSSDHVKVFLYQILRGLKYLH

SSGVIHRDLKPGNILLNGNCDMKLCDFGLSR
| ...|||.||||.|.| || .|.||||| |
SANILHRDIKPGNLLVNSNCVLKICDFGLAR
Kinase LmjF13.1640.AA ERK5 147-278 40 1.1e-37 131.55 In-house 27-152 (295) Show / Hide 
Range on Protein: 147-278
Range on HMM: 27-152/295
Sequence Identity: 40% (54 aa)

VAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYVH
|||||.   || .   .| .||.|.||  . | ||. . .. .|  | .      . |.| | |||. ||  .. |.| .... .|.  ||... | |.|
VAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYS-----EMKDVYVVFDLMESDLHQIIHSNQPFTLEHIRYFLYQILRGLKYMH

SSGVIHRDLKPGNILLNGNCDMKLCDFGLSRG
|  |||||||| |.| | ||..|. |||. ||
SAQVIHRDLKPSNLLVNENCELKIGDFGMARG
Kinase LmjF13.1640.AA Pkinase 147-277 31 5.8e-36 128.24 Pfam 27-160 (293) Show / Hide 
Range on Protein: 147-277
Range on HMM: 27-160/293
Sequence Identity: 31% (46 aa)

VAIKKVTKVFDDLVDGRRILR--EIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDT-----DLGALLR--SSQEI--AMDQLRFIA
||.|.. |. ..    .. .|  ||.... | .||||||| .. .             |.||.|.....      || ....  ..  .   .....|..
VAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----------KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

YQLMKVLVYVHSSGVIHRDLKPGNILLNGNCDM----KLCDFGLSR
||. . | | || |.||||||| |||.. |..     |.|||||..
YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAK
Kinase LmjF13.1640.AA CDK 166-277 35 1.7e-30 94.65 In-house 56-161 (284) Show / Hide 
Range on Protein: 166-277
Range on HMM: 56-161/284
Sequence Identity: 35% (42 aa)

LREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAF-DDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYVHSSGVIHRDLKPGNILLNG
.|||.||. |  |||||.|..|    ..  .     .   .|.| . ||.||  ...          . . .||.. | | || ...|||||| |||.| 
IREISLLKEL--HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN

NCD-----MKLCDFGLSR
|        |. ||||.|
NGEVKCGRLKIADFGLAR
Kinase LmjF13.1640.AA ERK1 147-290 41 1.7e-29 104.34 In-house 27-161 (289) Show / Hide 
Range on Protein: 147-290
Range on HMM: 27-161/289
Sequence Identity: 41% (60 aa)

VAIKKVTKVFDDLVDGRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDDIYLVTDLMDTDLGALLRSSQEIAMDQLRFIAYQLMKVLVYVH
|||||.   |.      | |||||.|   . | ||. . .. |      |..  .. |.|.| .||.|||  ||. .|... | . .  ||... | |.|
VAIKKIS-PFEHQTYCQRTLREIKILTRFK-HENIINIQDIIR------ADTIEQMRDVYIVQCLMETDLYKLLK-TQHLSNDHICYFLYQILRGLKYIH

SSGVIHRDLKPGNILLNGNCDMKLCDFGLSRGGVPAWPHERTLT
|  |.|||||| |.|||  ||.|.||||| |   |   |   ||
SANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLT
Kinase LmjF13.1640.AA MAPK-Unclassified 332-391 33 4.6e-25 87.23 In-house 403-494 (575) Show / Hide 
Range on Protein: 332-391
Range on HMM: 403-494/575
Sequence Identity: 33% (31 aa)

YSLTDYVVTRYYRAPE-LLIMGRYNHAIDMWSAGCILAEMVLR-----------RPLFTGAN--------------------YLSQLALILE
| .| |||||.||||| .| |. |  ..|.||.|||.|||...           ||||.| .                    . .|. .|..
YHMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFD
Kinase LmjF13.1640.AA p38 333-391 45 6.2e-25 81.92 In-house 159-218 (289) Show / Hide 
Range on Protein: 333-391
Range on HMM: 159-218/289
Sequence Identity: 45% (27 aa)

SLTDYVVTRYYRAPE-LLIMGRYNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILE
..|.||.|| ||||| .|  ..|. ..|.|| |||.||.. .|.|| | ....||  |..
EMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMK
Kinase LmjF13.1640.AA ERK 334-392 50 7.6e-25 88.87 In-house 173-232 (307) Show / Hide 
Range on Protein: 334-392
Range on HMM: 173-232/307
Sequence Identity: 50% (30 aa)

LTDYVVTRYYRAPE-LLIMGRYNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILET
.|.||.||.||||| .|    |. |.|.||.|||.|||. |.||| |..|. |. .|...
MTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQI
Kinase LmjF13.1640.AA CDK 327-392 44 1.1e-24 75.81 In-house 170-240 (284) Show / Hide 
Range on Protein: 327-392
Range on HMM: 170-240/284
Sequence Identity: 44% (32 aa)

KQPPLYSLTDYVVTRYYRAPELLI-MGRYN--HAIDMWSAGCILAEMVL---RRPLFTGANYLSQLALILET
. .|.  .|  |||. |||||||    .|.   .|||||.|||.|||..   |.||| | . . || .| ..
S-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRI
Kinase LmjF13.1640.AA ERK7 316-392 46 2.5e-23 76.39 In-house 147-222 (292) Show / Hide 
Range on Protein: 316-392
Range on HMM: 147-222/292
Sequence Identity: 46% (36 aa)

ARGASSAPHAAKQPPLYSLTDYVVTRYYRAPELLIMG-RYNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILET
||  .. .. ..| |   ||.|| || ||||| |.   ||  ..|||| ||||.||.  .|.| |   . |. .||||
ARSIAQQEEYDEQNPM--LTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRGKPMFPGTSTMNQIEKILET
Kinase LmjF13.1640.AA ERK5 316-391 46 9.3e-21 72.66 In-house 150-223 (295) Show / Hide 
Range on Protein: 316-391
Range on HMM: 150-223/295
Sequence Identity: 46% (36 aa)

ARGASSAPHAAKQPPLYSLTDYVVTRYYRAPELLI-MGRYNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILE
||| .    . .|   . .|.|| ||.||||||.. .  |  |||.|| |||. ||. || .| | ||. || ||..
ARGLCTFSPDKHQ---MFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIFGEMIARRQMFPGKNYIHQLQLIMM
Kinase LmjF13.1640.AA nmo 334-391 49 3.3e-20 58.28 In-house 160-218 (292) Show / Hide 
Range on Protein: 334-391
Range on HMM: 160-218/292
Sequence Identity: 49% (29 aa)

LTDYVVTRYYRAPELLIMGR-YNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILE
.|  ||| ||||||.|.  | |  |.|.|| ||| ||.. || ||  .. . || .| .
MTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRILFQAQSPIQQLQMITD
Kinase LmjF13.1640.AA ERK1 334-390 56 4.1e-19 68.29 In-house 160-217 (289) Show / Hide 
Range on Protein: 334-390
Range on HMM: 160-217/289
Sequence Identity: 56% (33 aa)

LTDYVVTRYYRAPELLIMGR-YNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALIL
||.|| ||.|||||...  . |  .||.|| |||||||.  ||.| |  || || .||
LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHIL
Kinase LmjF13.1640.AA Pkinase 325-394 33 2e-16 59.15 Pfam 159-232 (293) Show / Hide 
Range on Protein: 325-394
Range on HMM: 159-232/293
Sequence Identity: 33% (26 aa)

AAK--QPPLYSLTDYVVTRYYRAPELLI-MGRYNHAIDMWSAGCILAEMVLRRPLFTGA----NYLSQLALILETPG
|..    .   .|....|..|.|||..     | ...||||.||||.||...||.| |.    | ..|...| .. |
AKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMG
Kinase LmjF13.1640.AA CDK 464-488 48 2.6e-10 29.02 In-house 260-284 (284) Show / Hide 
Range on Protein: 464-488
Range on HMM: 260-284/284
Sequence Identity: 48% (12 aa)

LIAKLLSFDPRKRPTALEALRDPFF
|. |.| .|| || .| .|| .|.|
LLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF13.1640.AA CMGC 464-488 52 2.7e-10 29.06 In-house 489-513 (513) Show / Hide 
Range on Protein: 464-488
Range on HMM: 489-513/513
Sequence Identity: 52% (13 aa)

LIAKLLSFDPRKRPTALEALRDPFF
|. |.| .|| ||.|| .||. |.|
LLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF13.1640.AA TyrKc 52-487 13 2.5e-09 -71.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-487
Range on HMM: 1-280/280
Sequence Identity: 13% (65 aa)

FEVLNGIGYGAYGVVCAAVDLRLVASSVYYNEAMRTIEEEGRIVTRQRRGHDAPVYFRTRAVLDEAGRGGPVRVPHLYSEPFKRRTLARGEVSPFVAIKK
 . .  .| ||.|.|. ..                                                                            ||.|.
ITLGKKLGEGAFGEVYKGTWK------------------------------------------------------------------------IQVAVKM

VTKVFDDLVDGRRILREIKLLRYL-QGHPNIVRLMEVGRPPAPTGASSSAAF---DDIYLVTDLMDT-DLGALLRSSQE-IAMDQLRFIAYQLMKVLVYV
. .        . ..||..... |   |||||||  | . .          |   . ...|. .|.  ||   ||.... . |..|  ...|  .   | 
LKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-------FMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYL

HSSGVIHRDLKPGNILLNGNCDMKLCDFGLSRGGVPA---------WP-----HERTLTAVA-TAAESSAKELEDWGLFCWSSSA--------------A
|| ..|||||   |.|.. |  .| .|||||| .                   ...|.  .  .| |.          ..  ...               
HSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--------NYGKFTTKSDVWSFGVCMWEIFT

RGASSAPH---AAKQPPLYSLTDYVVTRYYRAPELL---IMGRYNHAIDMWSAGCILAEMVLRRPLFTGANYLSQLALILETPGLRGVPQTPEEAAALFE
.|..  |         . . .  || ..|.. .      .                                                            
YGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------------------------------

GGEEGKHFINDILFHKTARRRDPLTLSDQVHSQVLFHSTLFGFKVDVPISLGILIAKLLSFDPRKRPTALEALRDPF
                                          | |  |  .  .. .   .|| .|||  |  .. |
------------------------------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase LmjF13.1640.AA MAPK 52-76 44 4.4e-08 23.8 In-house 1-34 (328) Show / Hide 
Range on Protein: 52-76
Range on HMM: 1-34/328
Sequence Identity: 44% (15 aa)

FEVLNGIGYGAYGVVCAAVDLR---------LVA
.. |  ||.|||||||.|.| |          ||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVA
Kinase LmjF13.1640.AA MAPK 464-488 56 9.4e-08 22.64 In-house 304-328 (328) Show / Hide 
Range on Protein: 464-488
Range on HMM: 304-328/328
Sequence Identity: 56% (14 aa)

LIAKLLSFDPRKRPTALEALRDPFF
|. |.| ||| || |. |||. |.|
LLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF13.1640.AA Pkinase 457-488 37 1.2e-07 28.13 Pfam 262-293 (293) Show / Hide 
Range on Protein: 457-488
Range on HMM: 262-293/293
Sequence Identity: 37% (12 aa)

VPISLGILIAKLLSFDPRKRPTALEALRDPFF
.. ..  .| ..| .|| ||||| ..| .|.|
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF13.1640.AA ERK 52-71 55 2.8e-07 23.35 In-house 1-20 (307) Show / Hide 
Range on Protein: 52-71
Range on HMM: 1-20/307
Sequence Identity: 55% (11 aa)

FEVLNGIGYGAYGVVCAAVD
.. .. ||.|||||||.|.|
YQIIKQIGHGAYGVVCSAID
Kinase LmjF13.1640.AA MAPK-Unclassified 464-488 48 2e-06 18.84 In-house 551-575 (575) Show / Hide 
Range on Protein: 464-488
Range on HMM: 551-575/575
Sequence Identity: 48% (12 aa)

LIAKLLSFDPRKRPTALEALRDPFF
.. |.| |.|.|| || .||  |.|
FVQKMLQFNPWKRITADQALEHPYF
Kinase LmjF13.1640.AA ERK 464-488 52 4e-06 18.84 In-house 283-307 (307) Show / Hide 
Range on Protein: 464-488
Range on HMM: 283-307/307
Sequence Identity: 52% (13 aa)

LIAKLLSFDPRKRPTALEALRDPFF
|. |.| ||| || |. |.|. |.|
LLEKMLVFDPDKRITVEECLEHPYF
Kinase LmjF13.1640.AA p38 464-488 52 4e-06 16.66 In-house 265-289 (289) Show / Hide 
Range on Protein: 464-488
Range on HMM: 265-289/289
Sequence Identity: 52% (13 aa)

LIAKLLSFDPRKRPTALEALRDPFF
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LLEKMLELDPDKRITAEEAMQHPYF
Kinase LmjF13.1640.AA ERK7 464-488 48 3.3e-05 13.42 In-house 268-292 (292) Show / Hide 
Range on Protein: 464-488
Range on HMM: 268-292/292
Sequence Identity: 48% (12 aa)

LIAKLLSFDPRKRPTALEALRDPFF
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LLKRLLVFNPKKRLTAEQALQHPYV
Kinase LmjF13.1640.AA nmo 464-488 40 3.7e-05 11.13 In-house 268-292 (292) Show / Hide 
Range on Protein: 464-488
Range on HMM: 268-292/292
Sequence Identity: 40% (10 aa)

LIAKLLSFDPRKRPTALEALRDPFF
|....| ||| ||  . .||  |. 
LLCRMLHFDPDKRISCKDALAHPYL
Kinase LmjF13.1640.AA ERK5 464-488 44 8.6e-05 13.38 In-house 271-295 (295) Show / Hide 
Range on Protein: 464-488
Range on HMM: 271-295/295
Sequence Identity: 44% (11 aa)

LIAKLLSFDPRKRPTALEALRDPFF
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LLARMLRFEPSERITVNKALQHPFL
Kinase LmjF13.1640.AA ERK5 52-70 52 9.5e-05 13.22 In-house 1-19 (295) Show / Hide 
Range on Protein: 52-70
Range on HMM: 1-19/295
Sequence Identity: 52% (10 aa)

FEVLNGIGYGAYGVVCAAV
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YKIIEKIGNGAYGVVCSAR
Kinase LmjF13.1640.AA Pkinase_Tyr 147-277 32 0.000119 16.38 Pfam 31-159 (270) Show / Hide 
Range on Protein: 147-277
Range on HMM: 31-159/270
Sequence Identity: 32% (46 aa)

VAIKKVTKVFDDLVD--GRRILREIKLLRYLQGHPNIVRLMEVGRPPAPTGASSSAAFDD--IYLVTDLMDT-DLGALLRS----SQEIAMDQLRFIAYQ
||.|.. |   .  .   .  .||.|... |  |||||||. |               .   ||.|. .|   ||   ||.     | . | .|  ...|
VAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT----------DQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQ

LMKVLVYVHSSGVIHRDLKPGNILLNGNCDMKLCDFGLSR
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IAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase LmjF13.1640.AA ERK7 52-73 45 0.000189 10.78 In-house 1-22 (292) Show / Hide 
Range on Protein: 52-73
Range on HMM: 1-22/292
Sequence Identity: 45% (10 aa)

FEVLNGIGYGAYGVVCAAVDLR
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YEIRKRLGKGAYGIVWKAYDKR
Kinase LmjF13.1640.AA p38 52-71 50 0.000414 9.62 In-house 1-20 (289) Show / Hide 
Range on Protein: 52-71
Range on HMM: 1-20/289
Sequence Identity: 50% (10 aa)

FEVLNGIGYGAYGVVCAAVD
.. |  .| |||| ||.|.|
YQNLQPVGSGAYGQVCKAED
Kinase LmjF13.1640.AA MAPK-Unclassified 52-71 55 0.002164 7.51 In-house 1-20 (575) Show / Hide 
Range on Protein: 52-71
Range on HMM: 1-20/575
Sequence Identity: 55% (11 aa)

FEVLNGIGYGAYGVVCAAVD
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YEYQKNIGSGAYGQVCRAMD
Kinase LmjF13.1640.AA CDK 52-73 50 0.002267 6.46 In-house 1-22 (284) Show / Hide 
Range on Protein: 52-73
Range on HMM: 1-22/284
Sequence Identity: 50% (11 aa)

FEVLNGIGYGAYGVVCAAVDLR
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YEKLEKIGEGTYGVVYKARDKQ
Kinase LmjF13.1640.AA ERK1 464-488 48 0.004833 7.26 In-house 265-289 (289) Show / Hide 
Range on Protein: 464-488
Range on HMM: 265-289/289
Sequence Identity: 48% (12 aa)

LIAKLLSFDPRKRPTALEALRDPFF
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LLDKMLTFNPHKRITVEEALAHPYL
Kinase LmjF13.1640.AA ERK1 52-71 55 0.006235 6.84 In-house 1-20 (289) Show / Hide 
Range on Protein: 52-71
Range on HMM: 1-20/289
Sequence Identity: 55% (11 aa)

FEVLNGIGYGAYGVVCAAVD
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YTNLQYIGEGAYGMVCSAYD
Kinase LmjF13.1640.AA nmo 52-73 45 0.009299 3.62 In-house 1-22 (292) Show / Hide 
Range on Protein: 52-73
Range on HMM: 1-22/292
Sequence Identity: 45% (10 aa)

FEVLNGIGYGAYGVVCAAVDLR
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IQPDRPIGYGAFGVVWSVTDPR
Kinase LmjF13.1640.AA Pkinase 52-71 25 6.652207 0.74 Pfam 1-20 (293) Show / Hide 
Range on Protein: 52-71
Range on HMM: 1-20/293
Sequence Identity: 25% (5 aa)

FEVLNGIGYGAYGVVCAAVD
....  || |..|.|. ...
YHIGRKIGSGSFGCVYKCHH