Gene LmjF30.3580 (L.major)

LmjF30.3580

Species: L.major
Alias: LmjF30.3580, LmajK093
External Links:
Annotation:

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
LmjF30.3580.AA Protein None 747 None Fasta, JSON
LmjF30.3580.kin_dom Protein Kinase Domain None 396 None Fasta, JSON

Protein domain

Protein domains of LmjF30.3580.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF30.3580.AA SRPK 394-549 50 3.1e-108 279.43 In-house 396-550 (554) Show / Hide 
Range on Protein: 394-549
Range on HMM: 396-550/554
Sequence Identity: 50% (79 aa)

LADFGNSCWTYKQFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDGKYRSYYYNS
.||.|| ||... ||.. |||||| ||||.| .|.|| |||| |||.|||.|| .||.|..|.|||||.||.|.. ||.|..| .  |  |||   . |.
IADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDDDHIAHIIELCGKIPWHFALS-GKYSREFFNK

KGDLRNIKDLQYWALEDVLHQRHKFTKKKAKEIADFLLPMLEYAPDTRATPAAMLR
||.||.|..|..| |..|| .  .. .. ||...|||.|||.| |  ||| . .|.
KGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQ
Kinase LmjF30.3580.AA SRPK 159-387 35 5.7e-100 257.62 In-house 1-269 (554) Show / Hide 
Range on Protein: 159-387
Range on HMM: 1-269/554
Sequence Identity: 35% (98 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPH-----------------------KNRCCARLNDYFKHTGPNG
|.|..||||| |||||| || | .|| ||||.||| .|.|.|.||||||. . ..||.                       .  ....| | |||.||||
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG

THVCMLFDVYGENLLSLMERYEYRGIPLPIVKCIARQVLIGLDHINSI-DIIHTDLKPENVLLST------------------PKHSIISLMKQFRPP--
.|.|| | | |.||| . ..|.|.|.|.. || |||||||||| . .  .|||||.|||||||.                   .. .  | |.| .|   
NHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEWTEWQKMGMQMPSSSMVQTAPQHQ

PLHQRPKLTERDPKTMTKSQRRRYYKKLAKEERKTFLGEDDGDHKSRGDEHGSNENGDADSEGSKTDPEWEVE
. .|  |... . | | | | . . .  .    |  . .|..|     ..   ..| ... ....  .| ..|
TQCQQQKMSKNKKKKMKKKQKQQQEQQEKNQQQKQQMEDDQNDN----EDNNQEDNDNEQDNKNNQNQENNME
Kinase LmjF30.3580.AA CMGC 159-549 15 9.8e-80 261.51 In-house 1-509 (513) Show / Hide 
Range on Protein: 159-549
Range on HMM: 1-509/513
Sequence Identity: 15% (92 aa)

YRVVKKLGWGYFSTVWLVWD--------------YQKERYQAMKIQKSAASYSEAAY-------------DEIKLLSEIM-EADPHK----------NRC
| ..||.|.| ...|.  .|               . ... |.|. |..  | | |              .|||.| ..  . || .          .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-CARLNDYFKHTGPNGT-------------HVCMLFDVYGENLLSLMERYE--YRG------------------------IPLPIVKCIARQVLIGLD--
 . .| |.|.| ...|.             |... |.  . .|. .....   |.|                        ...  .. ...|.| ||.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

HINSID--IIHTDLKPENVLLSTPKHSIISLMKQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKEERKTFLGEDDGDHKSRGDEHGSNENGDADSE
.. | .  |||.||||||.|..  . .| .. .      . .                                                          
YCHSHWGNIIHRDLKPENILINHNCELITRM-M------W-K----------------------------------------------------------

GSKTDPEWEVERFHH----------VILADFGNSCWTYKQ------------------------FTDEVQTRQYRCPEVILGEP----------YSTPID
 |                       . ..|||...|. .                         .|..|.|| || ||..|| .          |.||||
-S------------EDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPID

IWSCACMIFELITG--------QFLFDPKKGD-----DYSRDEDHLALMSELLGDLPESMRLG------DGKYRSYYYNSKGDLRNIKDLQ---------
.||..|...|..||        . || .. ..     ..... |.|... ..||  . .|           |.   ..| .. ....|...         
MWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN

----------------YWALEDVLHQRHKFTKK--------------------------------KAKEIADFLLPMLEYAPDTRATPAAMLR
                 |     ... ... ..                                  ..  |.|  ||.| || | |..  |.
HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQ
Kinase LmjF30.3580.AA CLK 159-554 25 5e-67 199.73 In-house 1-350 (350) Show / Hide 
Range on Protein: 159-554
Range on HMM: 1-350/350
Sequence Identity: 25% (105 aa)

YRVVKKLGWGYFSTVWLVWDYQKE-RYQAMKIQKSAASYSEAAYDEIK-LLSEIMEA-DPHKNRC--CARLNDYFKH-TGPNGTHVCMLFDVYGENLLSL
| .|..|| | |..|  .|| ... .| | || ...  | |||  ||.  .  | |. ||.. .   | ..||.|..  |    |.|..|. || .. ..
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHG----HICIVFELYGLSIYDF

MERYE------YRGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLLSTPKHSIISLMKQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKEE
|          |.. |.  .. .|.| .  .    .. ..|||||||| ... ..                     |  |... ....            
MKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRF--------------------THFDCTFKYNHKKKIN--------

RKTFLGEDDGDHKSRGDEHGSNENGDADSEGSKTDPEWEVERFHHVILADFGNSC---WTYKQFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFEL
                          . |     ...| |. . |. . |||.       .   .. |.||.|| |||||| ..|.| |.|| .| .|||
--------------------------KKS-NNCVCHYWHVKNT-HICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFEL

ITGQFLFDPKKGDDYSRDEDHLALMSELLG-DLPESM--RLG-DGKYRSYYYNSKGDLRNIKDLQYWALEDV--LHQRHKFTKKKAKEIADFLLPMLEYA
 ||  ||.   . |     .|||.| ...| ..| .|  |       . |.|. . | .. ..      | .  |.|  . ..  . .  | .  |||| 
YTGFTLFQ---THD---NREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYFYHNRLDWDWHNSDGRYVMENCKPLKQYMDCKDPEHRQLFDLIRKMLEYD

PDTRATPAAMLRDHDAF
|  | | .  | .|  |
PSKRITCKDAL-QHPFF
Kinase LmjF30.3580.AA S_TKc 159-554 15 2.2e-46 161.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 159-554
Range on HMM: 1-231/231
Sequence Identity: 15% (66 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGE---NLLSLMER
|....|.| | |..|.....    |. |.|| |      | .. ||..|..       .     .| |.| .     .|..| ..  .    .|......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKK

YEYRG----IPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLLSTPKHSIISLM-----KQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKEE
. ..|    .|   ......|.. .|... |  ||| ||||||.||..     | .      .|.                                   
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----------------------------------

RKTFLGEDDGDHKSRGDEHGSNENGDADSEGSKTDPEWEVERFHHVILADFGNSCWTYKQFTDEVQTRQYRCPEVILGEPYST-PIDIWSCACMIFELIT
                                                             |  . |. |. |||.   .|.. ..|.||| |...|...
-------------------------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDGKYRSYYYNSKGDLRNIKDLQYWALEDVLHQRHKFTKKKAKEIADFLLPMLEYAPDTRATPA
|. .|.            ....| ...|                                                  .|  ||.  .|.. |. | |  
GYPPFP------------QMQMMFKKIG-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-

AMLR-D-----HDAF
  |. .     |  |
EALQDEWDIKCHPWF
Kinase LmjF30.3580.AA Pkinase 159-554 17 1.5e-33 119.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 159-554
Range on HMM: 1-293/293
Sequence Identity: 17% (73 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYD-----EIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLM
|....|.| | |..|..  .   ..  |.|| |     |.  .      ||... ..     |.|    || |.|      ..|..| ..  .  |  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPN--IVRLYDWFED----KDHIYMVMEYCEGGLY-VM

ERY------EYRGI--PLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLLSTPKHSIISLMKQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKE
. .      .....  .   .|....|.| ||... |  ||| ||||||.|..  .  | .                                       
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA---------------------------------------

ERKTFLGEDDGDHKSRGDEHGSNENGDADSEGSKTDPEWEVERFHHVILADFGNSC---WTYKQFTDEVQTRQYRCPEVIL-GEPYSTPIDIWSCACMIF
                                             .| ..||| ..   . .  .|. . |. |. ||||. |..|....|.||| |...
---------------------------------------------CVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILY

ELITGQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDGKYRSYYYNSKGDLRNIKDLQYWALEDVLHQRHKFTKKKAKEIADFLLPMLEYAPDTR
|...|...|. .  .. . ...   .   . ..|...    . .....  .                      . .| ..  .|  ||.  .|.. |  |
EMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

ATPAAMLRDHDAF
 | |. .  |. |
PT-AEQILQHPWF
Kinase LmjF30.3580.AA DYRK 159-305 31 9.4e-32 111.82 In-house 1-146 (320) Show / Hide 
Range on Protein: 159-305
Range on HMM: 1-146/320
Sequence Identity: 31% (47 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLMERYEY
|.... .| |.|. |  .|| .   . |.|| ..  ..   |..|||.|. . ..||  .  | .. |||.| .    |.|. |. .  ||  .. ..  
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRN----HLCIVFELLSMNLYEFLKNNHF

RGI-PLPIVKCIARQVLIGLDHINSI-DIIHTDLKPENVLLSTP-KHSII
.|  .|  |. .|.|.| .|... .  .||| ||||||..|  | . | |
QGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTI
Kinase LmjF30.3580.AA DYRK2 159-297 29 3.6e-27 85.12 In-house 1-135 (318) Show / Hide 
Range on Protein: 159-297
Range on HMM: 1-135/318
Sequence Identity: 29% (41 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLMERYEY
| ... .| |.|  |  . |.  . . | |.      . . || ||. |..| . |.  .  | ...|||   .    |.|. |. .. || ... . ..
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRN----HHCITFELLSMNLYEYIKKNHF

RGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLL
 |. | .|   |...| .|.     .||| ||||||.||
QGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILL
Kinase LmjF30.3580.AA DYRK2 394-495 36 1.7e-22 69.69 In-house 145-245 (318) Show / Hide 
Range on Protein: 394-495
Range on HMM: 145-245/318
Sequence Identity: 36% (39 aa)

LADFGNSCWTYK-QFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDG-----KYR
..||| ||  .  ..   .|.| || |||||| .|...||.||  | . || ||. ||    |...    | .|.| |.|| .|..  .        ..|
VIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLF---PGENE---NDQFACMMEVLG-MPPKKFFDTWFYIHCFRR

SYYYNSKG
 |. ||..
KYFFNSHC
Kinase LmjF30.3580.AA DYRK1 159-305 32 4.5e-22 73.93 In-house 1-145 (321) Show / Hide 
Range on Protein: 159-305
Range on HMM: 1-145/321
Sequence Identity: 32% (48 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLMERYEY
| .   .| | |  |   .| |.. | |.|| |   .. . |  ||.||  . ..|. .     .|   |..      |.|. |..   ||  |.   ..
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFR----NHLCLVFELLSYNLYDLLRNTHF

RGIPLPIVKCIARQVLIGLDHINS--IDIIHTDLKPENVLLSTPKHSII
||. | ... .|.|..  |  . .  .|||| ||||||.||  || | |
RGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAI
Kinase LmjF30.3580.AA DYRK 394-554 27 1.4e-20 73.81 In-house 148-320 (320) Show / Hide 
Range on Protein: 394-554
Range on HMM: 148-320/320
Sequence Identity: 27% (50 aa)

LADFGNSCWTYKQFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDG--KYRSYYY
..||| ||   ....  .| | || |||||| ||...||.||  | . || ||  ||    |...    | ||.. |.||  |. | .  |  ... ...
VIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFP---GENE---YDQLACIMEVLGMPPKWM-IDKGRCRRKHKFF

NS----------KGDL----------RNIKDLQYWALEDVLHQRHKFTKKKAKEIADFLLPMLEYAPDTRATPAAMLRDHDAF
..          |..            ..|. ..  . .  .. .... .. ..  ||.. .|.. |. | ||.  |. |. |
DCFMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQFKDFIKKCLQWDPHKRITPSQALQ-HPWF
Kinase LmjF30.3580.AA HIPK 159-297 28 4e-20 59.63 In-house 1-134 (329) Show / Hide 
Range on Protein: 159-297
Range on HMM: 1-134/329
Sequence Identity: 28% (39 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLMERYEY
| |.  || | |  |   |    .   |.|| |  ..|.     |...|. . . ..       |  ..|.|      |.|. |..   ||   .   ..
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFV-RAYECFHHK----NHTCLVFEMLEQNLYDFQKQNKF

RGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLL
  .||  .. |  |||  | .. .. .|| ||||||..|
MPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIML
Kinase LmjF30.3580.AA Ciliate-E2 269-554 10 5.5e-20 65.29 In-house 165-365 (365) Show / Hide 
Range on Protein: 269-554
Range on HMM: 165-365/365
Sequence Identity: 10% (40 aa)

IARQVLIGLDHINSID-IIHTDLKPENVLLSTPKHSIISLMKQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKEERKTFLGEDDGDHKSRGDEHGS
...... .| .. |   ||| |.||||.|.                                                                      
YIACIILALEYLHSKNNIIHRDIKPENILF----------------------------------------------------------------------

NENGDADSEGSKTDPEWEVERFHHVILADFGNSCWTYKQFTDE--------------------------------------VQTRQYRCPEVILGEP---
                        . ..|||.|    |...|.                                      . |  | .||.. |..   
------------------------IKIIDFGLS----KKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDN

------YSTPIDIWSCACMIFELITGQFLFDPKKGDDYSRDEDHLALMSELLGDLPESMRLGDGKYRSYYYNSKGDLRNIKDLQYWALEDVLHQRHKFTK
      |.. .||||. ....|...|.. |                                                                   . .
QQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------------------------------------------------------------------QQQ

KKAKEIA----------------------------DFLLP----MLEYAPDTRATPAAMLRDHDAF
.| ..|                             |..      ||.. |. | | .  . .|  |
IKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF30.3580.AA DyrkP 391-450 46 1.4e-15 47.09 In-house 146-205 (323) Show / Hide 
Range on Protein: 391-450
Range on HMM: 146-205/323
Sequence Identity: 46% (28 aa)

HVILADFGNSCWTYKQFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLF
.| . ||| ||.        || | || ||||.|  |   ||.||  |.. || ||  ||
QVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLF
Kinase LmjF30.3580.AA DyrkP 159-297 31 2.3e-14 43.02 In-house 1-139 (323) Show / Hide 
Range on Protein: 159-297
Range on HMM: 1-139/323
Sequence Identity: 31% (45 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQKSAASYSEAAYDEIKLLSEIMEADPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLM----E
| ..  ||   ||      | | ..   |||      | . . ||||||  |        .   |  ||| |      |. .. ..  .||        |
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHK----EHLFIITELLKDNLYEFYKFNRE

RYEYRGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLL
  . |   .  .. |  |.||.||.| |. .|| ||||||.|.
NEQQRYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILM
Kinase LmjF30.3580.AA DYRK1 396-450 45 2.1e-13 42.94 In-house 149-203 (321) Show / Hide 
Range on Protein: 396-450
Range on HMM: 149-203/321
Sequence Identity: 45% (25 aa)

DFGNSCWTYKQFTDEVQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLF
||| || . .     .| | || |||.|| .|.. ||.||  |.. |. ||  ||
DFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF
Kinase LmjF30.3580.AA PRP4 412-451 47 6e-13 43.8 In-house 167-206 (320) Show / Hide 
Range on Protein: 412-451
Range on HMM: 167-206/320
Sequence Identity: 47% (19 aa)

QTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLFD
. | || ||.|.| ||   ||.|| .| ..|| || ..|.
VSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFP
Kinase LmjF30.3580.AA PRP4 159-298 27 1.3e-10 35.14 In-house 1-140 (320) Show / Hide 
Range on Protein: 159-298
Range on HMM: 1-140/320
Sequence Identity: 27% (40 aa)

YRVVKKLGWGYFSTVWLVWDYQKER-YQAMKIQKSAASYSEAAYDEIKLLSEIMEA--DPHKNRCCARLNDYFKHTGPNGTHVCMLFDVYGENLLSLMER
|||. . | | ||.|    |  . .   | ||  .  .       |.  |  . .|  |.     | |. . |.|      | |. |     ||  .. .
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHR----QHMCLVFECMSMNLREVLKK

Y-EYRGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLLS
|    |  |  |   |.| .. | |.   .|.| |.|| |.| .
YGKDVGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVN
Kinase LmjF30.3580.AA HIPK 411-451 46 2.7e-07 18.52 In-house 164-204 (329) Show / Hide 
Range on Protein: 411-451
Range on HMM: 164-204/329
Sequence Identity: 46% (19 aa)

VQTRQYRCPEVILGEPYSTPIDIWSCACMIFELITGQFLFD
.| | || ||.||| |.   .|.||  | | ||. |  |..
LQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYP
Kinase LmjF30.3580.AA TyrKc 159-554 12 8e-05 -144.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 159-554
Range on HMM: 1-280/280
Sequence Identity: 12% (55 aa)

YRVVKKLGWGYFSTVWL-VWDYQKERYQ-AMKIQKSAASYSEAAYDEIKLLSEI-MEADPHKNRCCARLNDYFKHTGP-----NGTHVCMLFDVYGENLL
 .  |||| | | .|.. .|.     .| | |  |. |   |. ..|.......       .. .  ||  .  . |          . | .  .  .|.
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--REDFMREARIMCKLGG-----HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLK

SLMERYEYRGIPLPIVKCIARQVLIGLDHINSIDIIHTDLKPENVLLSTPKHSIISLMKQFRPPPLHQRPKLTERDPKTMTKSQRRRYYKKLAKEERKTF
.   ... . ....    .. |.  | ... |  .|| ||   |.|.. ..                                                 
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------------------------------

LGEDDGDHKSRGDEHGSNENGDADSEGSKTDPEWEVERFHHVILADFGNSCWTYKQ----FTDEVQTRQY--RCP----------EVILGEPYSTPIDIW
                                        .|  .||| |   |        ... . .    .           |.|    ..|  |.|
----------------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SCACMIFELIT-GQFLFDP-----KKGDDYSRDEDHLALMSELLGDLPESMRLGDGKYRSYYYNSKGDLRNIKDLQYWALEDVLHQRHKFTKKKAKEIAD
|   ...|. | ||          .. ..  .. ..   |     |. . |                                      |     .|. .
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS-------------------------------------F-VCCPDEMYQ

FLLPMLEYAPDTRATPAAMLRDHDAF
  .   .. |. | | ..    |. |
IMKQCWHEDPEDRPTFSEI---HECF
Kinase LmjF30.3580.AA Ciliate-E2 159-191 30 0.00117 8.41 In-house 1-33 (365) Show / Hide 
Range on Protein: 159-191
Range on HMM: 1-33/365
Sequence Identity: 30% (10 aa)

YRVVKKLGWGYFSTVWLVWDYQKERYQAMKIQK
| ..||.| | |..|... .... . .|.||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID
Kinase LmjF30.3580.AA DYRK1 528-554 40 0.004407 6.1 In-house 296-321 (321) Show / Hide 
Range on Protein: 528-554
Range on HMM: 296-321/321
Sequence Identity: 40% (11 aa)

DFLLPMLEYAPDTRATPAAMLRDHDAF
| .. ||.| | .| ||   |. |  |
DLIKRMLQYDPKQRITPYYALQ-HSFF