Gene LmjF21.0270 (L.major)

LmjF21.0270

Species: L.major
Alias: LmajK188, LmjF21.0270
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
LmjF21.0270.AA Protein None 1140 None Fasta, JSON
LmjF21.0270.kin_dom Protein Kinase Domain None 404 None Fasta, JSON

Protein domain

Protein domains of LmjF21.0270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF21.0270.AA S_TKc 14-417 18 3e-68 233.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-417
Range on HMM: 1-231/231
Sequence Identity: 18% (76 aa)

YKLLKEVGRGGSALVYRAQDVATRKDVAVKQLFGNRPQDMEDWLREVDALHTLNSHHCPHVVKYLDHMQQHDRLFLVEEFTEH--GSLLRCLKENKK---
|..|...|.|. . ||..... | . ||.|..        |. .||.. |.     |.|..||..|..|  |.|..| |. ..  |.|.. .|....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDVVKLTDFALRSHGEDDHEDAERRTTAASTASAEALPPMRGSRAGRDAGEECSGSAL
   .|| .|..|.||.. || ..   |..| ||| .|||| .  ..|..|| |  .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

SEFRGSAYWAAPEILAGASKATA-ASDIWSVGCLAVELLTGAPPYFERPVYNAIYHILKSYYEVLCESEASRVGAGGTSCASTNPATPSAATGSGDDDGP
. | |. .. |||.|    . .  ..|.||.||.  |.|.| ||.     .........                                         
TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------------------------------

RGPRKKKNGAKDAGGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALLPPLPEDLHVSDECLSFLRMCFRPRAVD
                                                                                  |.|...|.| |..    .
----------------------------------------------------------------------------------SPEAKDFIRKCLQKDPEK

RPSAGELLH-------DLWF
||.| |.|.       . ||
RPTA-EALQDEWDIKCHPWF
Kinase LmjF21.0270.AA CAMK 19-417 12 4e-47 149.46 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-417
Range on HMM: 1-425/425
Sequence Identity: 12% (70 aa)

EVGRGGSALVYRAQDVATR------------KDVAVKQLFGN----------------------------RPQDMEDWLREVDALHTLNS----HHCPHV
. |||. . |.....  |             . ||.| .  .                            ||.|..  .||.. . .|..     . |..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYLDHMQQHD-------------------RLFLVE---EFTEHG----SLLRCLKEN---------------KKLPEDTACRYIYQVLTALYHMAPWGV
.| ..... ..                   ....|    |. . |     |.  ..|.               ....|. |.||. |.. |. ..   ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHGDLKASNILLFDND-----------------VVKLTDFALRSHGEDD--------HEDAERRTTAASTASAEALPPMRGSRAGRDAGEECS------G
|| |||  |||| ||.                  .|..|| .  . ...        ....|                              .      |
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------------------QWTTPTEG

SALSEFRGSAYWAA-PEILAG-------------ASKATAASDIWSVGCLAVELLTGAPPYFERP------------VYNAIY-HILKSYYE-VLCE---
  ...| |. . .| ||.| |                 . ..|.||.|..   .|.| ||. .               .. ..  |.|  |.    .   
QKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSP

-------------SEASRVGAGGTSCASTNPATPSAATGSGDDDGPRGPRKKKNGAKDAGGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGA
             |.                                                                                     
ISCNYGPEWWDDISDE------------------------------------------------------------------------------------

VSASEQNEVATPLCEAALLPPLPEDLHVSDECLSFLRMCFRPRAVDRPSAGELLHDLWF
                       .  .||.|| ...| . ..   .|... . | . |.
---------------------F-HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF21.0270.AA Ciliate-E2-Unclassified 14-417 13 1.4e-35 120.86 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-417
Range on HMM: 1-352/352
Sequence Identity: 13% (68 aa)

YKLLKEVGRGGSALVYRAQDVATRKDVAVKQLF-------GNRPQDMEDWLREVDALHTLN----------------SHHCPHVVKYLDHMQQHDRLFLV
||..|  |.|| . ||..|.  . .  | |..         .  .   . ..| ...  ..                .| .|..||.... |. . ...|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

EEFTEHGSLLRCLKENKK-----------------LPEDTAC-----RYIYQVLTALYHMAPWG-VVHGDLKASNILLFDND---VVKLTDFAL-RSHGE
 |. |.|.|. ..|..||                 ..|  |.     .|..|.| .| ..   . ..| |.| .|||. .|     .|..|| . .  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

DDHEDAERRTTAASTASAEALPPMRGSRAGRDAGEECSGSA----------LSEFRGSAYWA----APEILAG-ASKATAA--SDIWSVGCLAVELLTGA
.. .| ..                                           .. | |. .      |||.| |     ..|  .||||.|... |.|.| 
NNNCD-TNQ-------------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY

PPYF--ERPV------------YNAIYHILKSY--YEVLCESEASRVGAGGTSCASTNPATPSAATGSGDDDGPRGPRKKKNGAKDAGGAPSQKTDVASA
.|..   .              |. ...  .    ... .... .                                                       
YPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ-------------------------------------------------------

RRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALLPPLPEDLHVSDECLSFLR----MCFRPRAVDRPSAGELLHDLWF
                                                    . |.|.|.  |..     ..  .   |... ..|   ||
---------------------------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF21.0270.AA Ciliate-E2 14-417 12 1.4e-33 112.64 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-417
Range on HMM: 1-365/365
Sequence Identity: 12% (66 aa)

YKLLKEVGRGGSALVYRAQDVATRKDVA--------------------VKQLFGNRPQDMEDWLREVDALHTLN-------------SHHCPHVVKYLDH
||..|  |.|. . ||....  ..|..|                     . .  ..... | ...| . . ..|             .  .|...|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MQ--QHDRLFLVEEFTEHGSLLR-----CLKENKKLP------EDTACRYIYQVLT---------------ALYHMAPWG-VVHGDLKASNILLFDNDVV
 |  . . ..|| |. ..|.|.      ..|.|....      |  ......|.|                || ..   . ..| |.| .|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFAL--RSHGE--------------DDHEDAERRTTAASTASAEALPPMRGSRAGRDAGEECSGSALSEF----------RGSAYWAAPEILAGASK
|..|| |  . . .              . . | .| ..  .                              .           |...  ||||| | . 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD------------------------------QIIQQNMFNTICGTPGYMAPEILNGKKY

--------ATAASDIWSVGCLAVELLTGAPPYFERPVYNAIYHILKSYYEVLCESEASRVGAGGTSCASTNPATPSAATGSGDDDGPRGPRKKKNGAKDA
         . ..||||.|..  |.|.| ||.                                                                    
DNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------------------------------------------------------------------

GGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALLPPLPE--------------DLHVSDECLSFLRM----CFR
                                                      ..  .  | ||               ...|.||  ...     .. 
--------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ

PRAVDRPS-AGELLHDLWF
     |.. . ..|   ||
KDPEKRITGWEQILNHPWF
Kinase LmjF21.0270.AA Pkinase 14-156 25 1.3e-31 112.85 Pfam 1-156 (293) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-156/293
Sequence Identity: 25% (41 aa)

YKLLKEVGRGGSALVYRAQDVATRKDVAVKQLFGNRPQDME---DWL-REVDALHTLNSHHCPHVVKYLDHMQQHDRLFLVEEFTEHG----SLLRCLK-
|.... .|.|... ||..... |.| ||||..   .  . .   ... .|.  .. ||   .|..|...| .. .|.. .| |. |.|    .| . .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-ENKKL--PEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDVV----KLTDF
 .....  .|.....|.||.| .|...   |..| ||| .|||. .|...    |..||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF
Kinase LmjF21.0270.AA CAMKL 14-156 23 1.6e-27 84.79 In-house 1-173 (297) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-173/297
Sequence Identity: 23% (41 aa)

YKLLKEVGRGGSALVYRAQD-VATRKDVAVKQLFGNRPQDMEDWL---------------REVDALHTLNSHH-CPHVVKYLDHMQQHDR------LFLV
|...|. |.|. . |  |..   |.. ||.| .  .. .. .  .               ||.  .  ||     |...| .....  .       ..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

EEFTEHGS--LLRCLKEN----KKLPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDND--VVKLTDF
 |  . |.  |.  ....    ...||. |.||  |.. |....   |.|| |.|. |||| .|.  ..|..||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF
Kinase LmjF21.0270.AA STE 14-156 21 7.8e-27 91.85 In-house 1-191 (359) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-191/359
Sequence Identity: 21% (42 aa)

YKLLKEVGRGGSALVYRAQDVA---------------TRKDVAVKQLF--GNRP---------------QDMEDWLREVDALHTLNSHHCPHVVKYLDHM
.......|.|..  ||.| ..                | . .|.||.    ...               ..|.. |.|.. .. .|.  .|..|||... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

QQH-------DRLFLVEEFTEHGSLLRCLKEN--------------KKLPEDTACRYIYQVLTA-LYHMAPWGVVHGDLKASNILLFDNDVVKLTDF
 .        | |... |. . |||   .|..              ...||.  .....|.| . ||.    ...| |.|..||||     |||.||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDF
Kinase LmjF21.0270.AA RSK 17-249 26 1.8e-26 93.95 In-house 1-212 (278) Show / Hide 
Range on Protein: 17-249
Range on HMM: 1-212/278
Sequence Identity: 26% (65 aa)

LKEVGRGGSALVYRAQDV---ATRKDVAVKQLFG----NRPQDMEDWLREVDALHTLNSHHCPHVVKYLDHMQQHDRLFLVEEFTEHGSLLRCLKENKK-
||. |.||   |.  . .   .|..  |.|.|      .|  | .. ..|.. | . ..|  | .|.. .  |  . |.|. |. . | |.. |.. |  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQH--PFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--LPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFD---NDVVKLTDFALRSHGEDDHEDAERRTTAASTASAEALPPMRGSRAGRDAGEECS-G
  . ||.|| |....  |. |.   |..| ||| .|||. |   .  .||||| .   .                                     |. .
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------------RCDHN

SALSEFRGSAYWAAPEILAGAS-KA--TAASDIWSVGCLAVELLTGAPPY
. .  |....  .|||.|. |  .   ..| |.|| |.|  |.|||.||.
QWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPF
Kinase LmjF21.0270.AA ULK 14-156 22 2.4e-26 89.01 In-house 1-186 (329) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-186/329
Sequence Identity: 22% (42 aa)

YKLLKEVGRGGSALVYRAQDVATR----KDVAVKQLF---GNRPQDMED-------WLREVDALHTLN----SHH-CPHVVKYLDHMQQHDR--LFLVEE
| | .. | |  . ||.. .. |     ..||.|..     |. ... .         .|.. ...|.    . . .|..||..|  .  .   .... |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FTEHGSLLRCLKENKKLPEDT----------ACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDND------------VVKLTDF
. ..| |   .|.||||||||          |  ...| | .. ..   ...| |.| .|||. ...            |.|..||
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase LmjF21.0270.AA CMGC 14-156 18 2.5e-25 79.42 In-house 1-248 (513) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-248/513
Sequence Identity: 18% (47 aa)

YKLLKEVGRGGSALVYRAQD--------------VATRKDVAVKQLFGNRPQDMEDW------------LREVDALHTLN-SH-------------HCPH
|. .| .|.|  . ||...|                | . ||.| .. .   . .              |||.  |  ||  |             | ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVKYLDHMQQHD-----------------RLFLVEEFTEHGSLLRCLKENK---------KLPEDT------------ACRYI------YQVLTALY--H
.|| .|. . ..                  |.|| |. .| .|.. .|.|.         .|.|               . ..      ||.|..|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

MAPWG--VVHGDLKASNILLFDN--------------------DVVKLTDF
.   .  ..| ||| .|||. .|                    ...|. ||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF
Kinase LmjF21.0270.AA STE 208-417 14 3.3e-24 82.45 In-house 223-359 (359) Show / Hide 
Range on Protein: 208-417
Range on HMM: 223-359/359
Sequence Identity: 14% (34 aa)

FRGSAYWAAPEILAG-----ASKATAASDIWSVGCLAVELLTGAPPYFERPVYNAIYHILKSYYEVLCESEASRVGAGGTSCASTNPATPSAATGSGDDD
| |.  | |||.. .      .. .. .||||.||...|..|| ||... .   |...|...|. .  .                               
FVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ-Q-------------------------------

GPRGPRKKKNGAKDAGGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALL-------PPLPED------------
                                                                         .|       ||||..            
-----------------------------------------------------------------------FEQLCIVNGPPPPLPDHLSQNEMISYGGS

-----LHVSDECLSFLRMCFRPRAVDRPSAGELLH--DLWF
      ..|.|.  |.. |..    .||.| .||.    ..
GTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF21.0270.AA STE20 14-156 28 5.6e-18 62.52 In-house 1-161 (288) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-161/288
Sequence Identity: 28% (46 aa)

YKLLKEVGRGGSALVYRAQDVATRKD----VAVKQLFGNRP----QDMEDWLREVDALHTLNSHHCPHVVKYLDHMQQH----DRLFLVEEFTEHGSLLR
|.||...|.|..  ||.| .. | .     ||.|..  . .    ...|| . |.. .  .. |  |..|||..  . .    | |..| |. . |||. 
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-H--PNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD

CLK---ENKK------LPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDVVKLTDF
 .|   . .|      . |.      ..|| .| .    ...| |.|| |||| ..  |||.||
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADF
Kinase LmjF21.0270.AA Dicty2 14-156 33 2.1e-16 53.78 In-house 1-150 (264) Show / Hide 
Range on Protein: 14-156
Range on HMM: 1-150/264
Sequence Identity: 33% (51 aa)

YKLL-KEVGRGGSALVYRAQDVATRKDVAVKQLF---GNRPQDMEDW---LREVDALHTLNSHHCPHVVKYLDHMQQHDRLFLVEEFTEHGSLLRCLKEN
|..    .|.|... ||.. .  |   || ||         .. |       |.. |..|| ||    |||..| .  . |  . |. | |||   .|  
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLN-HHN--IVKYIEHIETENHLYIILEYIENGSLSKIIKKF

KKLPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDV---VKLTDF
 ..||   |.||||||  |      ||.| | ||.|||   . .   .||.||
GCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADF
Kinase LmjF21.0270.AA Pkinase 199-263 26 3.4e-15 54.8 Pfam 164-229 (293) Show / Hide 
Range on Protein: 199-263
Range on HMM: 164-229/293
Sequence Identity: 26% (18 aa)

ECSGSALSEFRGSAYWAAPEILAGASKATAASDIWSVGCLAVELLTGAPPYFER----PVYNAIYHILK
. ..| .. | |. ...|||.. |... . ..|.||.||.  |.|.| ||. ..    . .. .. | .
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICR
Kinase LmjF21.0270.AA TyrKc 14-415 16 7.9e-15 17.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-415
Range on HMM: 1-280/280
Sequence Identity: 16% (70 aa)

YKLLKEVGRGGSALVYRAQDVATRKDVAVKQLFGNRPQDMEDWLREVDALHTL-NSHHCPHVVKYLDHMQQH-------DRLFLVEEFTEHGSLLRCLKE
 .|.|. |.|    ||...      .|||| |  .    .|| .||   .. |    | |..|. .    |.       . |..| |. .||.|.  |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGG--HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NKK-LPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDVVKLTDFAL-RSHGEDDHE-DAERRTTAASTASAEA-LPPMRGSRAGRDAGEECS
... |. .. . . .|.     . .  ...| || | |.|. .| .|| .|| | | ...||..  ..   ..... .. . ||                
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP----------------

GSALSEFRGSAYWAAPEILAGASKA--TAASDIWSVGCLAVELLT-GAPPYFE-----RPVYNAIYHILKSYYEVLCES----EASRVGAGGTSCASTNP
            | ||| .    .   | .||.|| | .  |..| |..|| .      . . .| .. . |.    ..                     
----------IRWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------

ATPSAATGSGDDDGPRGPRKKKNGAKDAGGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALLPPLPEDLHVSDE
                                                                                               . .||
------------------------------------------------------------------------------------------F---VCCPDE

CLSFLRMCFRPRAVDRPSAGELLHDL
  .  ..| .  . |||.  |. ...
MYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF21.0270.AA Pkinase_Tyr 14-158 26 3.4e-14 48.7 Pfam 1-157 (270) Show / Hide 
Range on Protein: 14-158
Range on HMM: 1-157/270
Sequence Identity: 26% (42 aa)

YKLLKEVGRGGSALVYRAQDV----ATRKDVAVKQL-FGNRPQD--MEDWLREVDALHTL-NSHHCPHVVKYLDHMQ-QHDR--LFLVEEFTEHGSLLRC
 ...|. |.|    ||..        |. .|||| |  |  ...  .|| .||.  ...| .   .|..|...     | .   ...| |. .||.||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH---HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LKE----NKKLPEDTACRYIYQVLTALYHMAPWGVVHGDLKASNILLFDNDVVKLTDFAL
|..    ...|.  . . . .|.  .. . .  . .| || | |.|. .| ||| .|| |
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase LmjF21.0270.AA Dicty2 213-250 51 5.1e-12 38.28 In-house 172-210 (264) Show / Hide 
Range on Protein: 213-250
Range on HMM: 172-210/264
Sequence Identity: 51% (20 aa)

YWAAPEILAGAS-KATAASDIWSVGCLAVELLTGAPPYF
|| |||.       .. |.||||.||   ||||| |||.
YWMAPEVIQMSGNHCCTACDIWSLGCTIIELLTGNPPYW
Kinase LmjF21.0270.AA STE20 213-417 14 3.4e-11 37.47 In-house 187-288 (288) Show / Hide 
Range on Protein: 213-417
Range on HMM: 187-288/288
Sequence Identity: 14% (30 aa)

YWAAPEILAG----ASKATAASDIWSVGCLAVELLTGAPPYFERPVYNAIYHILKSYYEV--LCESEASRVGAGGTSCASTNPATPSAATGSGDDDGPRG
|| |||....     .. .  .||||.|  | |...| ||||. .   |...|.|.  .   | ..                                  
YWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-K--------------------------------

PRKKKNGAKDAGGAPSQKTDVASARRATTTTSTRNPPKEPVDAAKTAASSGAVSASEQNEVATPLCEAALLPPLPEDLHVSDECLSFLRMCFRPRAVDRP
                                                                              . |.|   |.  |      .||
----------------------------------------------------------------------------PHKWSPEFHDFVDKCLQKDPEKRP

SAGELLHDLWF
.| .||.  ..
TASQLLKHPFI
Kinase LmjF21.0270.AA CMGC 216-245 41 2.2e-07 19.32 In-house 293-331 (513) Show / Hide 
Range on Protein: 216-245
Range on HMM: 293-331/513
Sequence Identity: 41% (16 aa)

APEILAGA---------SKATAASDIWSVGCLAVELLTG
||||| |.          . | . |.|||||   |..||
APEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTG
Kinase LmjF21.0270.AA ULK 208-251 33 1e-06 19.25 In-house 211-258 (329) Show / Hide 
Range on Protein: 208-251
Range on HMM: 211-258/329
Sequence Identity: 33% (16 aa)

FRGSAYWAAPEILA---GASKAT-AASDIWSVGCLAVELLTGAPPYFE
..|. .  ||.||    .  . . . .||||.||.  |.|.| ||...
LCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYA
Kinase LmjF21.0270.AA Dicty2 378-417 45 1e-06 19.24 In-house 227-264 (264) Show / Hide 
Range on Protein: 378-417
Range on HMM: 227-264/264
Sequence Identity: 45% (18 aa)

PPLPEDLHVSDECLSFLRMCFRPRAVDRPSAGELLHDLWF
||||.|  .| ||. ||  ||      |..| .|||  |.
PPLPND--ISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase LmjF21.0270.AA Pkinase 386-417 34 2.8e-05 19.75 Pfam 262-293 (293) Show / Hide 
Range on Protein: 386-417
Range on HMM: 262-293/293
Sequence Identity: 34% (11 aa)

VSDECLSFLRMCFRPRAVDRPSAGELLHDLWF
.|.||..|.. |...   .||.| ..|.. ||
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF21.0270.AA CAMKL 201-236 39 0.00021 9.8 In-house 186-223 (297) Show / Hide 
Range on Protein: 201-236
Range on HMM: 186-223/297
Sequence Identity: 39% (15 aa)

SGSALSEFRGSAYWAAPEILAG--ASKATAASDIWSVG
.|  |..| ||   .||||..|   .    . |||| |
PGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCG
Kinase LmjF21.0270.AA CAMKL 381-417 24 0.000249 9.56 In-house 262-297 (297) Show / Hide 
Range on Protein: 381-417
Range on HMM: 262-297/297
Sequence Identity: 24% (9 aa)

PEDLHVSDECLSFLRMCFRPRAVDRPSAGELLHDLWF
|  .||| .| ...|    .   .||.. ... . |.
PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase LmjF21.0270.AA RSK 378-417 20 0.037811 4.1 In-house 234-278 (278) Show / Hide 
Range on Protein: 378-417
Range on HMM: 234-278/278
Sequence Identity: 20% (9 aa)

PPLPEDLHVSDECLSFLRMCFRPRAVDRPS-----AGELLHDLWF
...|..  .|.|. ...|...     .|..     | |.. . ||
LTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase LmjF21.0270.AA CMGC 383-417 14 0.044093 1.59 In-house 479-513 (513) Show / Hide 
Range on Protein: 383-417
Range on HMM: 479-513/513
Sequence Identity: 14% (5 aa)

DLHVSDECLSFLRMCFRPRAVDRPSAGELLHDLWF
... ..... .|  ...    .|..| . |   .|
RKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF