Gene 90455.m00097 (T.vaginalis)

90455.m00097

Species: T.vaginalis
Alias: 90455.m00097, TvagK0875
External Links:
Annotation:

Classification

Group: Other
Family: VPS15

Sequence

Name Sequence Type Origin Length Description Download
90455.m00097.AA Protein None 1014 None Fasta, JSON
90455.m00097.kin_dom Protein Kinase Domain None 140 None Fasta, JSON

Protein domain

Protein domains of 90455.m00097.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90455.m00097.AA VPS15 101-285 33 5e-34 115.11 In-house 71-286 (296) Show / Hide 
Range on Protein: 101-285
Range on HMM: 71-286/296
Sequence Identity: 33% (72 aa)

DRQVYLVRPYITHSLQSRMNDYPELTNIEKDWIAYQIIRAVQNIHSNG-YIHGDIKPENILLTDRLQVLITDFSPYKPKYLRRSQPNYFLHYFNYNGS-S
|.  |..| |  |.|  |    | |..||| ||| |.  |.  .|  |   |||||.||||.|    ...||| ..|| ||    |  |. .|   .. .
DKAAYMMRQYVKHNLYDRISTRPFLQMIEKKWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADFTFFFDTSRRRT

SYIAPERVVESLPQTPVSLQ-------------------------CADIFSLGCVLAFLYTGG-STIFNFTTIQDYANGDLTPL--QALDRVKDENKRNY
.|||||| |. . |   |.                            ||||.|||.| |.. |   .|..   . | .|  .|.  | . .  ||. || 
CYIAPERFVSNTEQDQDSNNGNMRDIHTDSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNL

IKELIQLD-PNYRLQA
.. .|| | | .|. .
CHHMIQKDNPMKRMSC
Kinase 90455.m00097.AA AGC 136-172 46 5.2e-16 36.42 In-house 161-199 (395) Show / Hide 
Range on Protein: 136-172
Range on HMM: 161-199/395
Sequence Identity: 46% (18 aa)

QIIRAVQNIHS-NGYIHGD-IKPENILLTDRLQVLITDF
.|. |.. .|| .|.|| | .|||||||...  . .|||
CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF
Kinase 90455.m00097.AA CMGC 101-172 21 5.5e-16 48.13 In-house 127-248 (513) Show / Hide 
Range on Protein: 101-172
Range on HMM: 127-248/513
Sequence Identity: 21% (26 aa)

DRQVYLVRPYITHSLQSRMNDYP---------ELTNIE-------------KDWI-----AYQIIRAVQ--NIHSNG--YIHGDIKPENILLTDR-----
....|||  |. |.|   . ...         .|.  .             |  .     .|||.|..    .||..   || |.||||||....     
FNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELIT

---------------LQVLITDF
                .. | ||
RMMWKSEDWNPCQKNGRLKICDF
Kinase 90455.m00097.AA PDK1 136-172 56 4.6e-15 42.07 In-house 118-154 (307) Show / Hide 
Range on Protein: 136-172
Range on HMM: 118-154/307
Sequence Identity: 56% (21 aa)

QIIRAVQNIHSNGYIHGDIKPENILLTDRLQVLITDF
.|| |....|||| || |.|||||||.    ..||||
EIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDF
Kinase 90455.m00097.AA Ciliate-E2 133-297 17 5.2e-15 47.94 In-house 150-365 (365) Show / Hide 
Range on Protein: 133-297
Range on HMM: 150-365/365
Sequence Identity: 17% (44 aa)

IAYQIIR---------------AVQNIHSNG-YIHGDIKPENILLTDRLQVLITDFS-------PYKPKYLRRSQPNYFLHYFNYN--------------
| .||..               |.. .||..  || ||||||||.     . |.||        ... ..   .| . ..  .|..              
IMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQN

------GSSSYIAPERVVESLP-----QTPVSLQCADIFSLGCVLAFLYTGGSTIFNFTTIQDYANGDLTPLQALDRVKDENKR----------------
      |.  | ||| .... .     .       .||.|||..| .. .|                            ...|                 
MFNTICGTPGYMAPE-ILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------------------QQQIKQCKIDFPCPEWQKDTQC

----------------NYIKE----LIQLDPNYRLQAFGQVDSYYPPWF
                . ||     ..| ||. |..  |  .    |||
IQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
S_TKc 90455.m00097.AA S_TKc 23-297 19 1.1e-14 38.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-297
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

IQVENSIYDGTFMLSFKAFNTKLNKDIAVKAFLIPEDDNGIRDQQVLSVIESSKQIFDKLIRQEYKLKG----CLVGNYHLAD-RQVYLVRPYITH---S
 .. . |  |.|   .|. ..| ..  |.|                            . ||.| ..       .|  |   .   .|.|  |. .   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGD

LQSRMNDYPE------LTNIEKDWIAYQIIRAVQNIHSNGYIHGDIKPENILLTDRLQVLITDFSPYKPKYLRRSQPNYFLHYFNYNGSSSYIAPERVVE
| ... ...       ..  .   ..|||..|.. .||.| || |.|||||||..  .. |.||   .                 . |.  |.||| .  
LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL--

SLPQTPVSLQCADIFSLGCVLAFLYTGGSTIFNFTTIQDYANGDLTPLQALDRVKDENKRNYIKELIQLDPNYRLQAFGQVDSYY----PPWF
     . .   .|. |.||.|. ... | . |   ..|   .  .          ..  .. |. . | ||. |. |     .       |||
-----GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90455.m00097.AA Ciliate-E1 29-223 19 1.5e-14 44.11 In-house 1-202 (202) Show / Hide 
Range on Protein: 29-223
Range on HMM: 1-202/202
Sequence Identity: 19% (42 aa)

IYDGTFMLSFKAFNTKLN-KDIAVKAFLIPEDDNGIRDQ-QVLSVIESSKQIFDKLIRQEYKLKGCLVGNYHLADRQVY-LVRPYITHSLQSRMN-----
|  | | . |||.. . | . .|.| ...    .....| . ...|.  ..|.. .. ..| ..  ..  . . . ... ..  .  .||.  ..     
IGNGSFSIVFKAKQQNNNYNQVAQKIINC----CFNYNQNHFQDEIKEYYKIMK-FKKECYIIQ--IIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRL

--------DYPELTNIEKDWIAYQIIRAVQNIHSNGYIHGDIKPENILLTDRLQVLITDFSPYK-PKYLRRSQPNYFLHYFNYNGSSSYIAPERVVESLP
        .. ..|  .|  |..|.| ... .|... ||.||||.||| ..  . ...||.  |  |.   .| .|. .  .|  .  |  |  . |   
EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCP-EQ-EHNK

QTPVSLQCADIF
. ... .  ||.
NQKINYK-SDIY
Kinase 90455.m00097.AA Ciliate-E2-Unclassified 114-235 17 2.9e-14 45.9 In-house 107-266 (352) Show / Hide 
Range on Protein: 114-235
Range on HMM: 107-266/352
Sequence Identity: 17% (30 aa)

SLQSRMNDYPE-----------------LTNIEKD-----WIAYQIIRAVQNIHSNG-YIHGDIKPENILLTDRL---QVLITDFSPYK-----------
.|.  .....                  .|  .        ...||. . . .|...  || ||||||||...     .. |.||.  |           
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

----------PKYLRRSQPNYFLHYFNYNGSSSYIAPERVVESLPQTPVSLQCADIFSLGCVLAFLYTG
           ..  ... ....  .       | |||   .  . .. .  ..||.|||..| .. .|
QQQKMQIWKQQMMWTFCGTPNYMP-Q-------YTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFG
Kinase 90455.m00097.AA Ciliate-C1 136-172 48 1.5e-13 30.99 In-house 137-173 (328) Show / Hide 
Range on Protein: 136-172
Range on HMM: 137-173/328
Sequence Identity: 48% (18 aa)

QIIRAVQNIHSNGYIHGDIKPENILLTDRLQVLITDF
| | ..| ||.|.. | |.||||||| .  .  |.||
QLINVIQYIHQNNICHRDLKPENILLDENFNLKIADF
Kinase 90455.m00097.AA CAMK 136-172 35 2.6e-13 38.54 In-house 187-240 (425) Show / Hide 
Range on Protein: 136-172
Range on HMM: 187-240/425
Sequence Identity: 35% (19 aa)

QIIRAVQNIHSNGYIHGDIKPENILLTDR-----------------LQVLITDF
||. ||. .||.. .| |.|||||||.|.                  .. |.||
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 90455.m00097.AA Ciliate-E3 133-172 41 5.2e-09 24.55 In-house 108-150 (202) Show / Hide 
Range on Protein: 133-172
Range on HMM: 108-150/202
Sequence Identity: 41% (18 aa)

IAYQIIRAVQNIHSNGYIHGDIKPENILLTDRL---QVLITDF
|. |||. .  ||.   ||.||||.|||.  ..    . | ||
ICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDF
Kinase 90455.m00097.AA Pkinase 133-172 43 6.6e-09 32.58 Pfam 113-156 (293) Show / Hide 
Range on Protein: 133-172
Range on HMM: 113-156/293
Sequence Identity: 43% (19 aa)

IAYQIIRAVQNIHSNGYIHGDIKPENILLTDRLQV----LITDF
..|||.|... .||.| || |.||||||. .. ..     |.||
YMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF
Kinase 90455.m00097.AA Ciliate-E3 23-55 33 2.8e-05 12.77 In-house 1-33 (202) Show / Hide 
Range on Protein: 23-55
Range on HMM: 1-33/202
Sequence Identity: 33% (11 aa)

IQVENSIYDGTFMLSFKAFNTKLNKDIAVKAFL
. |   .  | | . .|||.. .|.|.| || .
YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAII
Kinase 90455.m00097.AA TyrKc 23-223 12 0.000325 -154.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-223
Range on HMM: 1-280/280
Sequence Identity: 12% (38 aa)

IQVENSIYDGTFMLSFKAFNTKLNKDIAVKAFLIPEDDNGIRDQQVLSVIESSKQIFD--KLIRQEY-------KLKGCLVG---NYHLADRQVYLVRPY
|. .  .  | |   .|.  .    . |||                       . . .  .. .. .       .| |. .    |  . . ....|  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEY

ITH-SLQSRMNDYPE-LTNIEKDWIAYQIIRAVQNIHSNGYIHGDIKPENILLTDRLQVLITDFS---PYKPK--------YLRRS---QPN--------
  | .|...  .. . |.. ..  ...|| .  . .||...|| |.   |.|......| |.||      . .        | | .   . .        
MPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

----YFLHYFNY----------------NGSSSY-------IAPERVVESLPQT-----PVS-------------------------------LQCADIF
     . . |.                 .| . |       . ...|.| . |      | .                                .. ..|
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 90455.m00097.AA CMGC 221-240 37 0.018661 2.84 In-house 317-343 (513) Show / Hide 
Range on Protein: 221-240
Range on HMM: 317-343/513
Sequence Identity: 37% (10 aa)

DIFSLGCVLAFLYTG-------GSTIF
|. |.||..| .|||       | ..|
DMWSVGCIFAEMYTGYQSLIFRGKPLF
Kinase 90455.m00097.AA Pkinase 196-235 27 0.64232 4.33 Pfam 173-208 (293) Show / Hide 
Range on Protein: 196-235
Range on HMM: 173-208/293
Sequence Identity: 27% (11 aa)

GSSSYIAPERVVESLPQTPVSLQCADIFSLGCVLAFLYTG
|.. |.||| .       .   . .|..|.||.|. ...|
GTPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCG