Gene 95054.m00075 (T.vaginalis)
95054.m00075
Species: T.vaginalis
Alias: 95054.m00075, TvagK0506
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 95054.m00075.AA | Protein | None | 379 | None | Fasta, JSON |
| 95054.m00075.kin_dom | Protein Kinase Domain | None | 238 | None | Fasta, JSON |
Protein domains of 95054.m00075.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 95054.m00075.AA | CK1 | 15-133 | 18 | 6.3e-20 | 66.25 | In-house | 1-155 (339) | Show / Hide |
Range on Protein: 15-133 Range on HMM: 1-155/339 Sequence Identity: 18% (29 aa) FIIDELLEKGDTC-NIYIA-----TDPNTR-----KKYVLKLESIDSK--AKTLEIELENYALLKG--------------------SKYFPIIHSNGSTQ . . ... .| || . .| .. ..|..|.|...|. .|..| . |..|.| ........ | .. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED N-WRYISMELLGPTIEKFQT--ILKGKTYSRESTVKISRQMLCCIQELHEKNIIH . ..|. |.||||..|.. . .. | ....| ||| ....|....|| DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIH |
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| Kinase | 95054.m00075.AA | CK1 | 183-255 | 28 | 1.8e-15 | 50.46 | In-house | 249-339 (339) | Show / Hide |
Range on Protein: 183-255 Range on HMM: 249-339/339 Sequence Identity: 28% (26 aa) SRRNDLLNWFYTTLILIDGK--LPWSSLTDHKK-----IEQMKNTVTIPQLCAS------------LPDDYQQIYSYIINLKNDEKPDYNRI .|| || |||. . ...|. |||. ..|..| .|.|| . ... .|... .|. || .|| ...||| | GRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | 95054.m00075.AA | TTBKL | 183-259 | 26 | 3.8e-15 | 47.67 | In-house | 207-288 (288) | Show / Hide |
Range on Protein: 183-259 Range on HMM: 207-288/288 Sequence Identity: 26% (22 aa) SRRNDLLNWFYTTLILIDGKLPWSSLTDHKKIEQMKNTVTIPQLCAS------LPDDYQQIYSYIINLKNDEKPDYNRILQLI .| .|| |.|.. | .| |||....|...||.||. . .|. .|. .. .. .|.. . ||| |.... GRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | 95054.m00075.AA | TTBKL | 15-133 | 21 | 4.4e-13 | 40.57 | In-house | 1-125 (288) | Show / Hide |
Range on Protein: 15-133 Range on HMM: 1-125/288 Sequence Identity: 21% (27 aa) FIIDELLEKGDTCNIYIATDPNTRKK-YVLKLESID-SK-AKTLEIELENYALLK--GSKYFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKT-YS . | ... .| .| . | .. |. ...| |. .. .....|.. .| ||..||..| | ... ... |.|.|| . . .. | | WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS RESTVKISRQMLCCIQELHEKNIIH ..... |. | | .....|.. .|| DGTWSRIGIQCLYALKQMHDCGFIH |
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| Kinase | 95054.m00075.AA | CK1-Unclassified | 15-133 | 25 | 1.6e-12 | 33.28 | In-house | 1-127 (244) | Show / Hide |
Range on Protein: 15-133 Range on HMM: 1-127/244 Sequence Identity: 25% (33 aa) FIIDELLEKGDTCNIYIATDPNTRKKYVLKLESIDSKAKTLEIELENYALLKGSK-------YFPIIHSNGST--QNWRYISMELLGPTIEKFQTILKGK . . | . | ..|| ... .| ... .|||. .|| ..| .| . |.. . ..| .. | .. .. |.|||| .|. . ..| YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK TYSRESTVKISRQMLCCIQELHEKNIIH | . | ||. |. ||.||.|| -FSLKTVLMIADQMIQRIEYLHNKNFIH |
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| Kinase | 95054.m00075.AA | CK1 | 15-133 | 24 | 2.3e-12 | 39.04 | In-house | 1-128 (271) | Show / Hide |
Range on Protein: 15-133 Range on HMM: 1-128/271 Sequence Identity: 24% (32 aa) FIIDELLEKGDTCNIYIATDPNTRKK--YVLKLESIDSKAKTLEIELENYALLKG------SKYFPIIHSNGST--QNWRYISMELLGPTIEKFQTILKG . . . . | . || ... ..... . |||...||. | .| | |.| ....| .. | .. .. |.|||| |. . .. YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR KTYSRESTVKISRQMLCCIQELHEKNIIH | | .. | ||.. |. .|.||.|| K-FSLKTVLMIADQMIQRIEYVHNKNFIH |
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| Kinase | 95054.m00075.AA | CK1-D | 15-143 | 28 | 2.8e-11 | 35.87 | In-house | 1-128 (261) | Show / Hide |
Range on Protein: 15-143 Range on HMM: 1-128/261 Sequence Identity: 28% (37 aa) FIIDELLEKGDTCNIYIATDPNTRKKYVLKLESIDSKAKTLEIELENYALLKGSKYFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKTYSRESTVK . | . | .|| |. .| .|||.| .| |.|| | ...| | |. |. .. . |.|||| .| . | .| . YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRK-FSLKTVLM ISRQMLCCIQELHEKNIIHGEIHSKHFVI .. ||.| |. .| .| || .| |.. LADQMICRIEYIHCRNFIHRDIKPDNFLM |
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| Kinase | 95054.m00075.AA | CK1-A | 15-143 | 24 | 1.4e-09 | 29.8 | In-house | 1-128 (261) | Show / Hide |
Range on Protein: 15-143 Range on HMM: 1-128/261 Sequence Identity: 24% (31 aa) FIIDELLEKGDTCNIYIATDPNTRKKYVLKLESIDSKAKTLEIELENYALLKGSKYFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKTYSRESTVK . . . | ||.. . . .|.|| . . | | | .|.| .| .. |. ... . |.|||| .| . | . .. . YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCK-RRFTMKTVLM ISRQMLCCIQELHEKNIIHGEIHSKHFVI . ||. | .|||| || .| |.. LADQMIMRIEYVHEKNFIHRDIKPDNFLM |
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| Kinase | 95054.m00075.AA | CK1-D | 171-255 | 36 | 1.5e-09 | 29.69 | In-house | 175-261 (261) | Show / Hide |
Range on Protein: 171-255 Range on HMM: 175-261/261 Sequence Identity: 36% (33 aa) NTKKKIHQDKIYSRRNDLLNWFYTTLILIDGKLPWSSLTDHKK------IEQMKNTVTIPQLCASLPDDYQQIYSYIINLKNDEKPDYNRI || . | | ||| || | . | ||| | | | . | . | .||. .| ..|| | ||| |.|||| . NTHQGIEQ----SRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | 95054.m00075.AA | TTBK | 177-255 | 27 | 2.2e-08 | 25.74 | In-house | 179-257 (257) | Show / Hide |
Range on Protein: 177-255 Range on HMM: 179-257/257 Sequence Identity: 27% (22 aa) HQDKIYSRRNDLLNWFYTTLILIDGKLPWSSLTDHKKIEQMKNTVTIPQLCASLPDDYQQIYSYIINLKNDEKPDYNRI |. . |. || || . | ||| . | .. .||. . | .| . .| | |. ..||| | HRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | 95054.m00075.AA | CK1-A | 183-255 | 31 | 4.1e-08 | 24.59 | In-house | 183-261 (261) | Show / Hide |
Range on Protein: 183-255 Range on HMM: 183-261/261 Sequence Identity: 31% (25 aa) SRRNDLLNWFYTTLILIDGKLPWSSLT------DHKKIEQMKNTVTIPQLCASLPDDYQQIYSYIINLKNDEKPDYNRI ||| |. | . ||||| .. || | ...| ||| | .. . .|. ||. .|.||| . SRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | 95054.m00075.AA | Worm6 | 15-127 | 23 | 6.6e-08 | 24.79 | In-house | 1-121 (279) | Show / Hide |
Range on Protein: 15-127 Range on HMM: 1-121/279 Sequence Identity: 23% (28 aa) FIIDELLEKGDTCNIYIATDPNTRK--KYVLKLES--IDSKAKTLEIELENYALLKGSK--YFPIIHSNGSTQN--WRYISMELLGPTIEKFQTILKGKT . ..... .|. .| ..| . | ....|.|. .| . | .|. ..| .| .|. | | ..| .|| |.|.|. . . .. WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK YSRESTVKISRQMLCCIQELH .| . ||..|.| |..|| FSMGTGLKIAIQCLEAIEDLH |
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| Kinase | 95054.m00075.AA | CK1 | 213-253 | 33 | 1.7e-07 | 22.06 | In-house | 230-271 (271) | Show / Hide |
Range on Protein: 213-253 Range on HMM: 230-271/271 Sequence Identity: 33% (14 aa) KIEQMKNTVTIPQLCAS-LPDDYQQIYSYIINLKNDEKPDYN || .| .... |||. .| .. |. .|. .||||| KIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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| Kinase | 95054.m00075.AA | Ciliate-C3 | 113-156 | 36 | 2e-06 | 19.41 | In-house | 99-140 (140) | Show / Hide |
Range on Protein: 113-156 Range on HMM: 99-140/140 Sequence Identity: 36% (16 aa) VKISRQMLCCIQELHEKNIIHGEIHSKHFVIKPDATFPITLLDL ..||.|.| |. ||| ||.||.| . .| . | ..| LQISKQILQAIDYLHEHNIVHGDIKFSNILI--NSKDEIKIIDF |
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| Kinase | 95054.m00075.AA | Worm6 | 183-255 | 27 | 7e-06 | 17.36 | In-house | 199-279 (279) | Show / Hide |
Range on Protein: 183-255 Range on HMM: 199-279/279 Sequence Identity: 27% (22 aa) SRRNDLLNWFYTTLILIDGKLPWSSLTDHKKIE-QMKNTVTIPQ------LCASLPD-DYQQIYSYIINLKNDEKPDYNRI .|. |. ||| . .| |.||| ..||. | . | .. . . . | ... | || ... ..|||. | CRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | 95054.m00075.AA | S_TKc | 15-264 | 9 | 1.1e-05 | -93.58 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 15-264
Range on HMM: 1-231/231
Sequence Identity: 9% (27 aa)
FIIDELLEKGDTCNIYIATDPNTRKKYVLKLESIDSKAKTLEIELENYALLKGSKYFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKT-------Y
. | ... || | ... .| ... .| . .... |.. . .. .. . . |. ||... ...| . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF
SRESTVKISRQMLCCIQELHEKNIIHGEIHSKHFVIKPDATFPITLLDLNKAWLTTSRPPPKQNTKKKIHQDKIYSRRND-----------LLNWFYTT-
. . .. .|..| .. .|...||| . . | . | | . . .| |..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----------------------TTFCGTPWYMAPEVL--GYGKC
-----------LILIDGKLPWSSLTDHKKIEQMKNTVTIPQLCASLPDDYQQIYSYIINLKNDEKPDYNRILQ----LINTAMI
... |. |.. .... ..... ... .. . . . .. | .|| . .
KCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 95054.m00075.AA | CK1-G | 212-255 | 28 | 2e-05 | 14.26 | In-house | 221-266 (266) | Show / Hide |
Range on Protein: 212-255 Range on HMM: 221-266/266 Sequence Identity: 28% (13 aa) KKIEQMKNTVTIPQLCAS--LPDDYQQIYSYIINLKNDEKPDYNRI .|| . | . | || . .|... . |. .|. .|.|||. . QKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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| Kinase | 95054.m00075.AA | CK1-G | 44-143 | 23 | 4.7e-05 | 12.96 | In-house | 30-129 (266) | Show / Hide |
Range on Protein: 44-143 Range on HMM: 30-129/266 Sequence Identity: 23% (24 aa) KLESIDSKAKTLEIELENYALLKGSK-YFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKTYSRESTVKISRQMLCCIQELHEKNIIHGEIHSKHFV |.| . |.| | | | .| | | .. | . . |.|||| | . . ..| ... .. ||. ....|... | . . | KFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWC-DRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFL I | I |
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| Kinase | 95054.m00075.AA | CK1-Unclassified | 212-227 | 43 | 0.036128 | 2.22 | In-house | 229-244 (244) | Show / Hide |
Range on Protein: 212-227 Range on HMM: 229-244/244 Sequence Identity: 43% (7 aa) KKIEQMKNTVTIPQLC .|| || .... ||| EKIMEMKMSTPVEQLC |
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| Kinase | 95054.m00075.AA | TTBK | 29-128 | 21 | 0.090607 | 2.07 | In-house | 15-115 (257) | Show / Hide |
Range on Protein: 29-128 Range on HMM: 15-115/257 Sequence Identity: 21% (22 aa) IYIATDPNTR-KKYVLKLESIDSKAKTLEIELENYALLKGSKYFPIIHSNGSTQNWRYISMELLGPTIEKFQTILKGKTYSRESTVKISRQMLCCIQELH || |.| .. . .|.|| . . | .| | | .. | .. |. |.|.| ..| .|... |.| |.. | IYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIH E . S |
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