Gene 90925.m00118 (T.vaginalis)

90925.m00118

Species: T.vaginalis
Alias: 90925.m00118, TvagK0762
External Links:
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
90925.m00118.AA Protein None 335 None Fasta, JSON
90925.m00118.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of 90925.m00118.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90925.m00118.AA GSK 30-312 36 1.8e-95 292.06 In-house 1-328 (328) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-328/328
Sequence Identity: 36% (119 aa)

FKSVSVIDQGSFGIVYLAIGL-----NDET----CAIKCIPQDPKIR-SREIKVMLRL---HHHNCVKLRRHFQTH-DKKYD--RDVENIVMEYLPENLS
..   || .|||| || |.       ..|.     ||| . ||.. . .|| . | .|   .| |.|.|. .|..| .|| .  . ....||||.|..|.
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

NFDMKFVKNHDHIPIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFGSAKRPKL--GQNSICYAGSRLYRAIESFLHSETCGAPM
..  ..|||   .|||..||..|||| ||.. | .|  ||||| .|.|.||.|||||||||||||. .   .. .| |  || ||| | .. ..  .   
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQI

DIWSAGCVITRMLRGVNPIFASRTSEEMIDLTMNILGTPTPEDIQDMNVKF--SPTT-----QYKRKPLQI-------------------LLPS-HTPDD
|.||.|||.  || |  |.|. ..|  .. .  ..||||| |.|| ||..            |.|..|.|                    .. . ||...
DVWSCGCVMAEMLKG-QPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHTDMQ

-IIDLLNNIFVYSPKKRFTAAQCMQHPCF
 .|||.. ..|| ||||... ....|| |
DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 90925.m00118.AA CMGC 30-312 18 4.3e-80 262.72 In-house 1-513 (513) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-513/513
Sequence Identity: 18% (96 aa)

FKSVSVIDQGSFGIVYLAIG---------------LNDETCAIKCIPQDPKIRS----------------REIKVMLRL-----------------HHHN
.. ...| .|..|.|| ..                 ..| .||| | ...                    |||| . .|                 ||.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

CVKLRRHFQTHD-KKYDRD----------VENIVMEYLPENLSNFDMKFV----------KNHDH---------------IPIILVKLFAYQMFSGLN--
.|||. .|.... .... .            ..|.||.. .| ..  .             .. |               ..| ... ..||.. ||.  
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

HMHTIG--YIHRDIKTSNLLIDPET-------------------GVLKICDFGSAK--RPKLGQ--------------------NSICYAGSRLYRAIES
..|  .   ||||.| .|.||....                   |.|||||||.|.   |  ..                        |  .| ||| | 
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

FLHS---------ETCGAPMDIWSAGCVITRMLRG-------VNPIFASRTS-----------EEMIDLTMNILGTPT---------------PEDIQDM
 | .            . |.|.||.||..  |..|         |.|  ...            ..... ...|||||               .|.. .|
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

NVK------------------FSP-----------TTQYKRKPLQILLPSHTP----------------------------------DDIIDLLNNIFVY
. .                  .|.             ....||.. | | | .                                  .. ||||.....|
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

SPKKRFTAAQCMQHPCF
 |.|| ||.|..||| |
DPDKRITAEQALQHPYF
Kinase 90925.m00118.AA S_TKc 30-312 25 8.6e-61 209.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-231/231
Sequence Identity: 25% (75 aa)

FKSVSVIDQGSFGIVYLAIGLN-DETCAIKCIPQDPKIRSREIKVMLRLHHHNCVKLRRHFQTHDKKYDRDVENIVMEYLPENLSNFDMKFVKNHDH---
.. . .| .|.|| ||...  . .. .|||.|.   .   |||... . || | |||  .||.       |   .||||.. .| .     .|.  |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IPIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFGSAKRPKLGQNSICYAGSRLYRAIESFLHSETCGA-PMDIWSAGCVITR
  .|   .. ..||....|...|  | ||||.| .|.|.|    ..||||||.|..         . |.. |.| | .      |  . |.|| ||..  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLRGVNPIFASRTSEEMIDLTMNILGTPTPEDIQDMNVKFSPTTQYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCMQ-------HPCF
|| |  |          ........|                                 ... .|........ |.|| || ...|       || |
MLCGYPPFP-------QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90925.m00118.AA Pkinase 30-312 27 1e-52 186.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

FKSVSVIDQGSFGIVYLAIGLNDET-CAIKCIPQDPKIRSR--------EIKVMLRLHHHNCVKLRRHFQTHDKKYDRDVENIVMEYLPENL---SNFDM
.. ...| .|||| ||...  ...   |.|.|. . .  .         ||..|.||.| | |.|.. |...|. |      .||||..  |   . |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLF--

KFVK--NHDHI--PIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVL----KICDFGSAKR--PKLGQNSICYAGSRLYRAIESFLHSETC
 ...  .|  .  .   .| ..||...||...|  | ||||.| .|.||| ..|..    ||||||.||      ..    ..|.. |.| |  ....  
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

GAPMDIWSAGCVITRMLRGVNPIFASR----TSEEMIDLTMNILGTPTPEDIQDMNV--KFSPTTQYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRF
| . |.||.||..  || |  |.| ..    .  ... .  .|.|.|...|..  .    |. ... . ..   ..   .... .|...... . |||| 
GPKVDMWSCGCILYEMLCGR-PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRP

TAAQCMQHPCF
||.|..||| |
TAEQILQHPWF
Kinase 90925.m00118.AA CAMK 35-312 17 5.8e-40 125.98 In-house 1-425 (425) Show / Hide 
Range on Protein: 35-312
Range on HMM: 1-425/425
Sequence Identity: 17% (80 aa)

VIDQGSFGIVYLAIGLND-------------ETCAIKCIPQD-----------------------------PKIRS---REIKVMLR-------LHHHNC
.. .||||.|.|.|  |.             . .||| |. .                             || |    |||..| .       |.| | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLRRHFQ------------THDK--KYD-RDVENIVM---EYLPEN------LSNFDMK-----------FVKNHDHIPIILVKLFAYQMFSGLNHMHT
.||  ...            | .|    . ..   .||   || .        ..    .           .| .. ...   .. .  |. |.....| 
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS

IGYIHRDIKTSNLLIDPET----------------GVLKICDFGSA--KRPKL----------------------GQNSICYAGSRLYRA-IESFLH---
 . .|||.|  |.|.|                   . .||.||| |  ..|.                       ||    . |.  | |  | ..    
HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

----------SETCGAPMDIWSAGCVITRMLRGVNPIFASRTSEEM---------IDLTMNIL-GTPT-PED----------------IQDMNVKFSPTT
           . .| . |.||.|..   || |  |  ..  .|..          .|  .|. |  . |..                | |         
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE--------

QYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCMQHPCF
        .  . .  .. .||.... .. |.||.|..||..|| .
--------F-HH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 90925.m00118.AA Ciliate-E2 30-312 18 8.3e-37 123.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-365/365
Sequence Identity: 18% (74 aa)

FKSVSVIDQGSFGIVYLA----------IGLNDETC---------------AIKCI-PQDPKIRSREIKVM----------------LRLHHHNCVKLRR
.| . .| ||.||.||..          | ..| .                |.|.. ... .. ..||..|                 .| | | .|.  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

HFQ--THDKKYDRDVENIVMEYLPEN-----LSNFDMKFVKNHD---HIPIILVKLFAYQMFS---------------GLNHMHTIG-YIHRDIKTSNLL
.||  . .. |      .||||.  .     . |.. |. .. .    . .  .| . .| ..               .|...|  .  |||||| .|.|
CFQEKDDNNIY------LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENIL

IDPETGVLKICDFGSAKRPK------LGQNSICY---------------------------AGSRLYRAIESFLHSET--------CGAPMDIWSAGCVI
.      .||.||| .|. .      .. ...|.                           .|.  | | | .   .          .   ||||.|...
F------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

TRMLRGVNPIFASRTSEEMIDLTMNILGTPTPEDIQDMNVKFSPTTQYKRKPLQILL------PSHTPDDIIDLLNN----IFVYSPKKRFT-AAQCMQH
 .|| |  |                         .| .. |..   . ..|..| .       . . ... .||...    .... |.||.| . |...|
YEMLFGKPPF-----------------------QQQIKQCKIDFPCPEWQKDTQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNH

PCF
| |
PWF
Kinase 90925.m00118.AA ERK7 136-312 37 2.2e-32 107.82 In-house 107-292 (292) Show / Hide 
Range on Protein: 136-312
Range on HMM: 107-292/292
Sequence Identity: 37% (70 aa)

YQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFGSA----KRPK-LGQNSIC--YAGSRLYRAIESFLHSETCGAPMDIWSAGCVITRMLRGVN
||..  . .||    ||||.| ||.|.| |  ..|.|||| |    ....   || .   |   | ||| |  | |..     | || ||..  ||||  
YQLLRAIKYMHSGNVIHRDLKPSNILLDSEC-MVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEMLRG-K

PIFASRTSEEMIDLTMNILGTPTPEDIQDMNVKFSPT-----TQYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCMQHPCF
|.|.     . |.. ..... || |||.... ... .      | |||.|. ..| ...|| |||| .. |. |||| || |..|||  
PMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 90925.m00118.AA STE 30-312 18 4.2e-32 110.7 In-house 1-359 (359) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-359/359
Sequence Identity: 18% (72 aa)

FKSVSVIDQGSFGIVYLAIGLN----------------DETCAIKCIP---QDPKIRS-------------------REIKVMLRLH--HHNCVKLRRHF
.. ...| .|.|| ||.|.  .                 | .||| ..   ...|. .                   .|||.| ...  | | ||   ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

QTHDK-KYDRDVENIVMEYLP-ENLS---NFDMKFVKNHD-------HIPIILVKLFAYQMFSG-LNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFGS
   .. . ..|  .|.|||..   |.   .  ..  |...       ..|  ... ...|   | |.. |  ..|||||| .| |.       |.|||| 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGV

AKRPKL-----------------GQNSICYAGSRLYRAIESFLH-----SETCGAPMDIWSAGCVITRMLRGVNPIFA-SRTSEEMIDLTMNILGT----
...                    .|..   .|.  . | |  .      .  ...  |||| ||.|  |. |  | .  . ..  .  ..... .     
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----PTPEDIQD---------------MNVKFSPTTQYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCMQ--HPCF
     ..|  ..|                                  .|..  .. .| .|. ... |.|| || | ..  || .
LCIVNGPPPPLPDHLSQNEMISYGGSGTT------------------YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 90925.m00118.AA CDK 30-178 24 6.7e-32 99.22 In-house 1-161 (284) Show / Hide 
Range on Protein: 30-178
Range on HMM: 1-161/284
Sequence Identity: 24% (44 aa)

FKSVSVIDQGSFGIVYLAIGLN------DETCAIKCIPQDPK-------IRS----REIKVMLRLHHHNCVKLRRHFQTHDKKYDRDVE------NIVME
.. .  | .|..|.|| |. ..      .. .|.|.|  . .         .    |||. .  | |.| |||.  . |... ...          .|.|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFE

YLPENLSNFDMKFVKNHDHIPIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGV-----LKICDFGSAK
|..  |. . |.            .| . .|. .||...|  . .|||.|..|.||. ..|.     ||| ||| |.
YMDHDLKKY-MD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILIN-NNGEVKCGRLKIADFGLAR
Kinase 90925.m00118.AA RCK 30-220 28 4.3e-27 82.76 In-house 1-204 (298) Show / Hide 
Range on Protein: 30-220
Range on HMM: 1-204/298
Sequence Identity: 28% (60 aa)

FKSVSVIDQGSFGIVYLAIGL-NDETCAIKCIPQ-----DPKIRSREIKVMLRLH-HHNCVKLRRHFQTHD--KKYDRDVENIVMEYLPENLSNFDMKFV
 . .. .  |..| | .|. . . |  |||.  |     .  .. ||||.. .|. | | .||.  ..  |    |      .|.||. .||. . . | 
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLY------FVFEYMDMNLYQMMKDFK

KNHDH-IPIIL--VKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPE--------TGVLKICDFGSAKRPKLGQNSICYAGSRLYRAIESFLHSETCGA
.  .. .| .   .|   || . ||.|||. |. |||.|  |... ..        ....||.|||...     ..   | ..| ||| |  |.. .   
E-RRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNS

PMDIWSAGCVI
|||||. ||..
PMDIWAVGCIM
Kinase 90925.m00118.AA CDK-Unclassified 30-177 24 3.9e-22 69.5 In-house 1-173 (324) Show / Hide 
Range on Protein: 30-177
Range on HMM: 1-173/324
Sequence Identity: 24% (45 aa)

FKSVSVIDQGSFGIVYLAIGLN-DETCAIK--CIPQ--D------------PKIRSREIKVMLRLHHHNCVKLRRHFQTHDKKYDRDVEN----------
 .   .. .| ||.|..|| ..     |||   ...  .            . .  |||... ...|.|  |.    . |   ||.|             
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKF---MDMH---YDHDRCSKNPYYDNLHP

---IVMEYLPENLSNFDMKFVKNHDHIPIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPET----GVLKICDFGSA
   .|||| |  ..|   .   |        .. |. ||..|.. .|  . .|||||..|..|.  .     .||| |||.|
SFYMVMEYMPYTWYN---QLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQA
Kinase 90925.m00118.AA MAPK 211-312 31 4.2e-19 62.53 In-house 215-328 (328) Show / Hide 
Range on Protein: 211-312
Range on HMM: 215-328/328
Sequence Identity: 31% (36 aa)

MDIWSAGCVITRMLRGVNPIFASRTSEEMIDLTMNILGTPTPEDIQDMN--VKF-----SP--TTQYKRKPLQILLPS---HTPDDIIDLLNNIFVYSPK
.|.||.||    ||..  |.|  . . . . | |..||||..|.|| .    .      |    ..|..||.. ..|    .. .. ||||    | .|.
VDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPD

KRFTAAQCMQHPCF
|| |.....||| |
KRITVEEALQHPYF
Kinase 90925.m00118.AA CDK 212-312 26 2.4e-16 48.64 In-house 204-284 (284) Show / Hide 
Range on Protein: 212-312
Range on HMM: 204-284/284
Sequence Identity: 26% (28 aa)

DIWSAGCVITRMLR--GVNPIFASRTSEEMIDLTMNILGTPTPED---IQDMNVKFSPTTQYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQC
|.||.||..  |..     |.|  ..  . ...  .|.||||...   . ..                            ||||. ..| ||||..| |.
DMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQA

MQHPCF
.||| |
LQHPYF
Kinase 90925.m00118.AA MAPK 131-175 46 4.5e-14 44.85 In-house 117-162 (328) Show / Hide 
Range on Protein: 131-175
Range on HMM: 117-162/328
Sequence Identity: 46% (22 aa)

VKLFAYQMFSG--LNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFG
.. | ||.  |  | ..|  . ||||.| ||.|.. | . |||||||
IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN-ENCDLKICDFG
Kinase 90925.m00118.AA TyrKc 30-312 20 4.1e-12 -26.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-312
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

FKSVSVIDQGSFGIVYLAIGLNDETCAIKCIPQDPKIRS--REIKVMLRL--HHHNCVKLRRHFQTHDKKYDR---DVENIVMEYLPE-NLSNFDMKFVK
 .   ..  | ||.||...    ...|.|..  |  ..   ||...| .|  || | |.|     |...       .   ||||| |  .| .    . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRL-YGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKD----YLR

NHDH-IPIILVKLFAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFGSAKRPKLG----QNSICYA-----GSR--L---YRAIESFLHS--
.| . ..      |..|  .| .. |  ..||||. . | |.. .  . ||.||| ..  . .     ..  |      |..  |     |.|.. ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

--ETCGAPMDIWSAGCVITRML-RGVNPIFAS----RTSEEMIDLTMNILGTPTPED---IQDMNVKFSPTTQYKRKPLQILLPSHTPDDIIDLLNNIFV
  ..     |.|| | ..  .. .|  |         . .|.| . ..    | |..   .                        . ||.. ..      
TTKS-----DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------F-VCCPDEMYQIMKQCWH

YSPKKRFTAAQCMQHPCF
. |..| | ...  | ||
EDPEDRPTFSEI--HECF
Kinase 90925.m00118.AA RCK 267-312 41 9.6e-12 33.25 In-house 254-298 (298) Show / Hide 
Range on Protein: 267-312
Range on HMM: 254-298/298
Sequence Identity: 41% (19 aa)

QYKRKPLQILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCMQHPCF
|.|  ||. |.|.  . | |.|..    . |.|| ||.|. ||| |
QCKGMPLKQLIPN-CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 90925.m00118.AA CDK-Unclassified 212-312 28 6.5e-11 32.0 In-house 221-324 (324) Show / Hide 
Range on Protein: 212-312
Range on HMM: 221-324/324
Sequence Identity: 28% (30 aa)

DIWSAGCVITRMLRGVNPIFASRTSEEMIDLTMNILGTPTPE---DIQDMNVKFSPTTQYKRKPL-QILLPSHTPDDIIDLLNNIFVYSPKKRFTAAQCM
||||.||..  ...|. |||. ||  | .     .||||. .   |. .|    . .. || |     . |. .    .... .  .|.|..| .. .  
DIWSFGCIYAEWFQGK-PIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKHASENNCEFQMVMYQPYNRWKCMEIL

QHPCF
||| |
QHPWF
Kinase 90925.m00118.AA Pkinase_Tyr 30-85 24 3.3e-05 18.25 Pfam 1-69 (270) Show / Hide 
Range on Protein: 30-85
Range on HMM: 1-69/270
Sequence Identity: 24% (17 aa)

FKSVSVIDQGSFGIVYLAIGL-----NDETCAIKCIPQDPKIRS-------REIKVMLRL-HHHNCVKL
 .   .. .|.|| ||...       .. ..|.|.....   .        ||.|.|  | ||.| |.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL
Kinase 90925.m00118.AA Pkinase_Tyr 134-175 38 0.000749 13.67 Pfam 116-156 (270) Show / Hide 
Range on Protein: 134-175
Range on HMM: 116-156/270
Sequence Identity: 38% (16 aa)

FAYQMFSGLNHMHTIGYIHRDIKTSNLLIDPETGVLKICDFG
...|  .|... . ...||||. . | |.. |..| ||||||
MCWQIAKGMEYLESKNCIHRDLAARNCLVT-ENNVVKICDFG