Gene 91895.m00068 (T.vaginalis)

91895.m00068

Species: T.vaginalis
Alias: TvagK0602, 91895.m00068
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
91895.m00068.AA Protein None 347 None Fasta, JSON
91895.m00068.kin_dom Protein Kinase Domain None 294 None Fasta, JSON

Protein domain

Protein domains of 91895.m00068.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91895.m00068.AA CMGC 15-308 20 6e-97 319.12 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-513/513
Sequence Identity: 20% (105 aa)

FRIIEKIGTGTYGSVYKAVD--------------LDQKQIVALKVMK-SFNQKES---------VPLSFYRELNVLQTVS-----------------HDN
. ||.||| |||| |||..|               . ..|||.| .|  |  .|          .| . .||.  |. ..                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSYKGVWRYPD-----------------EICLALEYCETDLQKQLSCQP---------LLQPSQ------------VKSLM------CQLLSGLA--EL
||. . . ....                 ...|  ||...|| . .  ..          | . .            .|..|       |.| ||.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--FVHRDVKPANILIKGGKTL--------------------KITDFGLSRKLNSK-----------------------HLTSKVSSLAYRAPELIL
||..  ..||| ||.||||   ..|                    || ||||.|....                        ..|. |... |||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GS---------NNYNYSIDIWSAGVIFYELCTGEK---------FP----------SACSDLSQLDKIFRVTGTPS---------------PSSDDEKSP
|.         ..|...||.||.| ||.|. || .         ||          .  |.. ||.|||.| |||.               .  . ....
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

EPTDGD------------ILCQLPNWRLAS---MLHIYPRTLEQLLTDKLP-------------------------------QELADAVEIITSMLSLNP
 |.               ...      . |      ..|.....|  .. .                               ..  .|.. .  || ..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SKRPSALELLRNPFF
.||..| . |. |.|
DKRITAEQALQHPYF
Kinase 91895.m00068.AA S_TKc 15-308 25 3e-90 307.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-231/231
Sequence Identity: 25% (81 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKESVPLSFYRELNVLQTVSHDNIVSYKGVWRYPDEICLALEYCET---DLQKQLSCQPL----
..|..||| |..|.|||... . ..|||.|..|          ...||...|.   |.||| ...|..  |.... .|||..   || . .  ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LQPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKLNSKHLTSKVSSLAYRAPELILGSNNYNY-SIDIWSAGVIFYELC
  . . .....|.|....|. .|| |..|||.||.|||.    ..||.||||.|.|     |. . .. |.|||..     |.. ..|.|| |.|.||..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGEK-FPSACSDLSQLDKIFRVTGTPSPSSDDEKSPEPTDGDILCQLPNWRLASMLHIYPRTLEQLLTDKLPQELADAVEIITSMLSLNPSKRPSALELL
.|.  ||       |....|.. |                                                    .| ..|  .|  .|.|||.| |.|
CGYPPFP-------QMQMMFKKIG--------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EAL

R-------NPFF
.        |.|
QDEWDIKCHPWF
Kinase 91895.m00068.AA Pkinase 15-308 27 9.6e-81 279.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-293/293
Sequence Identity: 27% (86 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKESVPLSFYR--ELNVLQTVSHDNIVSYKGVWRYPDEICLALEYCET-----DLQKQLS--CQ
..|..||| |..|.|||... .  .|||.|..|  ..|.... .  |  |. ... ..|.||| ........|.|.. .||||      ||   .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PLL--QPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTL----KITDFGLSR---KLNSKHLTSKVSSLAYRAPELILGSNNYNYSIDIWSA
  .  .. ..|. | |.|.||. .|| |..|||.||.||||.   ..    ||.||||..     |.  .|. . .. |.|||.|.|.. | ...|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIFYELCTGEKFPSAC----SDLSQLDKIFRVTGTPSPSSDDEKSPEPTDGDILCQLPNWRLASMLHIYPRTLEQLLTDKLPQELADAVEIITSMLSLN
|.|.||...|.   . .    . ..|. .|.|. |.| ... .........  .                     . .. . .    .. ..|...| ..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------F-HWTF-HNWSEECKDFIKWCLCKD

PSKRPSALELLRNPFF
|.|||.| ..|  |.|
PKKRPTAEQILQHPWF
Kinase 91895.m00068.AA CDK 15-233 36 3.1e-77 246.63 In-house 1-248 (284) Show / Hide 
Range on Protein: 15-233
Range on HMM: 1-248/284
Sequence Identity: 36% (94 aa)

FRIIEKIGTGTYGSVYKAVDLDQK-----QIVALKVMKSFNQ-----KESVPLSFYRELNVLQTVSHDNIVSYKGVWRYP-----------DEICLALEY
. ..|||| |||| |||| |....     ||||||  .  |.     || .| .  || . |.   |.|||. . |                 . .  ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CETDLQKQLSCQPLLQPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKT-----LKITDFGLSRKLNS--------KHLTSKVSSLAYRAPEL
...|| | ..         .|..| |||.||. .|| ...||| ||.||||    .     |||.||||.|. ..        . .|..|  | ||||||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

ILGSNNYN--YSIDIWSAGVIFYELCT---GEKFPSACSDLSQLDKIFRVTGTPSPSS
 ||| .|.   .||.||.| ||.|. |   .. .    |.. ||.||||. |||....
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDN
Kinase 91895.m00068.AA CDC2 15-230 39 3.1e-67 205.52 In-house 1-229 (301) Show / Hide 
Range on Protein: 15-230
Range on HMM: 1-229/301
Sequence Identity: 39% (90 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKES--VPLSFYRELNVLQTVS-HDNIVSYKGVWRYPDEICLALEYCETDLQKQLS-CQPL---
.  ||||| |||| |||. |....||||||  .  .. |   || .  ||.  |.    |.|||. . |      . .  ||.. || | .   .|    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LQPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRK--LNSKHLT--SKVSSLAYRAPELILGSNNYNYSIDIWSAGVIFYEL
..|. |||.| |.|.|.. .|. . .||| || ||||    ..|| ||||.|    ... .|    |  | |||||. ||.  |. ..|.|| | ||.|.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---CTGEKFPSACSDLSQLDKIFRVTGTPS
   .| . . .. |   || ||||. |||.
FMDVTKKPLFHGDSEIDQLFKIFRILGTPN
Kinase 91895.m00068.AA MAPK 15-308 26 3.4e-63 216.25 In-house 1-328 (328) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-328/328
Sequence Identity: 26% (89 aa)

FRIIEKIGTGTYGSVYKAVDLD------QKQIVALKVMK-SFNQKESVPLSFYRELNVLQTV-SHDNIVSYKGVWRY------PD-----EICLALEYCE
..|...|| | || | .|.|        ....||.| .   |. . .     |||.  |.    |.||.. . . .       ..     .|..  |..|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME

TDLQKQLSCQPLLQPSQVKSLMCQLLSG--LAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKLNSK----------------HLTSKVSSLAYRA
|||.. . .|. |    ....| |.| |  |  .|||. .||| ||.|||.    .||| ||||.|.. ..                |.|  |.   |||
TDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PELILG--SNNYNYSIDIWSAGVIFYELCT-GEKFPSACSDLSQLDKIFRVTGTPSPSSDDEKSP-EPTDGDILCQL---PNWRLASMLHIYPRTLEQLL
||..|.  ...|. ..|.||.| || |. | .  .    . . |. .|. |.||| .  . .. .  .   . . .|   |.    .  ...| ..    
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF---

TDKLPQELADAVEIITSMLSLNPSKRPSALELLRNPFF
     .   .|.  .  || ..|.|| .. | |. |.|
-----NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 91895.m00068.AA CDK5 15-308 35 7.7e-63 197.2 In-house 1-287 (287) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-287/287
Sequence Identity: 35% (106 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKESVPLSFYRELNVLQTVSHDNIVSYKGVWRYPDEICLALEYCETDLQKQL-SCQPLLQPSQV
.  .|||| |||| |||| . . . |||||  .  .  | || .  ||  .|.   | |||    |      . |  |.|  || | . ||.  ...  .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRK--LNSKHLTSKVSSLAYRAPELILGSNNYNYSIDIWSAGVIFYELC-TGEKFP
||.| ||| |||  |.    ||| || | ||    .||  |||| |      .  .. |  | ||.|   .||  |. |||.||.| || |.  .|    
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

SACSDLSQLDKIFRVTGTPSPSSDDEKSPEPTDGDILCQLPNWR-LASMLHIYPRTL-EQLLTDKLPQELADAVEIITSMLSLNPSKRPSALELLRNPFF
   ..  || .||...|||.     .| |       . .||... ..  . .|| .   | .. || ... |   .   || .|| .| || . |. |.|
PGNDVEDQLKRIFKIMGTPC----EDKWPS------ITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMD---LLQKMLQCNPNQRISAKAALHHPYF
Kinase 91895.m00068.AA Ciliate-E2 15-308 19 6.1e-60 204.45 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-365/365
Sequence Identity: 19% (85 aa)

FRIIEKIGTGTYGSVYKA-VDLDQK-------------------QIVALKVMKSF--NQKESVP--LSFYRELN----------VLQTVSHDNIVSYKGV
. .|.|||.|..|||||. |...||                   . . .. ||..  ||.|..   .. .||.|          .|....|.||. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WR--YPDEICLALEYCET-DLQK-----QLSCQPLLQ------PSQVKSLMCQLLS---------------GLAELHSAG-FVHRDVKPANILIKGGKTL
.     . | | .|||.  ||..     .....  ..        ..| .| |.|.               .| .||| .  .||| || |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGLSRKLNSK---------------------------------HLTSKVSSLAYRAPELILGSNN--------YNYSIDIWSAGVIFYELCTGEK-
||.|||||.|.. .                                    . . .. | ||| . | ..        |.|..||||.|||.||...|.  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPSACSDLSQLDKIFRVTGTPSPSSDDEKSPEPTDGDILCQLPNWRLASMLHIYPRTLEQLLTDKLPQELA---------------------DAVEIITS
|                                                        ..| .  |.    .                     ..  .|  
F--------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK

----MLSLNPSKRPS-ALELLRNPFF
    ||  .|.||.. . ..| .|.|
FGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91895.m00068.AA CDK-DD1 15-229 36 3.3e-58 178.08 In-house 1-219 (379) Show / Hide 
Range on Protein: 15-229
Range on HMM: 1-219/379
Sequence Identity: 36% (81 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKESVPLSFYRELNVLQTVSHDNIVSYKGVWRYP--DEICLALEYCETDLQKQLSCQP-LLQPS
. ||.|.| |.||||.||.    . .||||  |  || .  |      |. |  ..  |||     .     ..  . .|| | || | .| .   .  .
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKVECKYLMQLRHCK--NIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSLP

QVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKLNS---KHLTSKVSSLAYRAPELILGSNNYNYSIDIWSAGVIFYELCTGEK
..|  . ||| |. |.|..|  |||.|||| ||     |||||||..        ||. ..| || ||.||| .|| .|   ||.|| | |  |. |.  
CIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNFY

FPSACSDLSQLDKIFRVTGTP
.    ..  ||. |.   |.|
MFAGSNEQQQLELICKLCGCP
Kinase 91895.m00068.AA Ciliate-E2-Unclassified 15-308 21 5.2e-57 195.72 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-352/352
Sequence Identity: 21% (83 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKE--SVPLSFYRELNVLQTVS--------------------HDNIVSYKGVWR--YPDEICLA
..||..||.| .|.|||... .|||. |.| ||.....   ..  .  ...| ....                     |.... .| ..     . |.. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYC------------------ETDLQKQLSCQPLLQPSQVK-----SLMCQLLSGLAELHSAG-FVHRDVKPANILI-KGGK--TLKITDFGLSRKLN-
.|||                    || ... ..  ..  |.|      .. |.|.||  ||. . ..||| || |||. ..||   .||.|||.|.|.. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----------------SKHLTSKVSSLAYR----APELILGSNNYN---YSIDIWSAGVIFYELCTGEKFPSACSD-------------------LSQLD
                ........ .. |     |||.. | |...   |..|||| |||.||...|. .|  . .                   | |  
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KIFRVTGTPSPS-SDDEKSPEPTDGDILCQLPNWRLASMLHIYPRTLEQLLTDKLPQELADAVE-IITSMLSLNPSKRPSALELLRNPFF
|   .   ..|  .                                      .....| .| .. .. .||  ||.||... ..|  |.|
KQKNIQFPKFPWQQ------------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91895.m00068.AA STE 15-207 24 8.1e-51 175.14 In-house 1-265 (359) Show / Hide 
Range on Protein: 15-207
Range on HMM: 1-265/359
Sequence Identity: 24% (66 aa)

FRIIEKIGTGTYGSVYKAVDLD---------------QKQIVALKVMKSFNQK---------------ESVPLSFYRELNVLQTVS--HDNIVSYKGVWR
...||||| |..|.||||.. .               ...|.| |.|.  |..               ..   .. .|.....  .  |.||| | |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YP-------DEICLALEYCE-TDLQKQLS-CQPLLQP-------------SQVKSLMCQLLSG-LAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSR
.        ||.....||..   | . .  .   ..|             ||..   .|.| | |. ||| . .|||.||||||.      |..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KLNS------------------KHLTSKVSSLAYRAPELILG-----SNNYNYSIDIWSAGVIFYELCTGE
.|..                  .. .. | .  . ||| |..     .. |... |||| |    |..||.
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase 91895.m00068.AA CRK7 110-233 31 7.8e-38 127.94 In-house 111-276 (343) Show / Hide 
Range on Protein: 110-233
Range on HMM: 111-276/343
Sequence Identity: 31% (52 aa)

PSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKLNS----KHLTSKVSSLAYRAPELILGSNNY------------------
..|.|..| ||| |.. .|  .| |||.| .|||.     .||.|||| |..||    . .| .|  | ||.||| ||  .|                  
HQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQL

--------------------NYSIDIWSAGVIFYELCTGEKFPSACSDLSQLDKIFRVTGTPSPSS
                    . .||.|| | |. || |..    .   . ||.||... |.| | .
SLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNN
Kinase 91895.m00068.AA Pkinase_Tyr 15-161 27 7.3e-22 74.67 Pfam 1-161 (270) Show / Hide 
Range on Protein: 15-161
Range on HMM: 1-161/270
Sequence Identity: 27% (45 aa)

FRIIEKIGTGTYGSVYKAVDL----DQKQIVALKVMKSFNQKES-VPLSFYRELNVLQTV-SHDNIVSYKGVWR-YPDE--ICLALEYCET-DLQKQLSC
 ....|.| | .|.|||..      ..|. || |..|    .|     .| ||.... .  .|.|||.. ||     .   |.. .||..  || . |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QPLLQPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKL
    .. | ...  .   |  .|.. |.| ...|||.   |.|.. ... ||.||||.| .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 91895.m00068.AA CRK7 15-75 40 1.3e-17 57.17 In-house 1-64 (343) Show / Hide 
Range on Protein: 15-75
Range on HMM: 1-64/343
Sequence Identity: 40% (26 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQ---KESVPLSFYRELNVLQTVSHDNIV
...|. || |||| ||||.... ...|||| ... |    ||  |    ||  .|.   |.|||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIV
Kinase 91895.m00068.AA TyrKc 15-308 21 1.3e-16 45.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-308
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

FRIIEKIGTGTYGSVYKAVDLDQKQIVALKVMKSFNQKESVPLSFYRELNVLQTV--SHDNIVSYKGVWRYP-------DEICLALEYCET-DLQKQL-S
 . ..|.| | .| |||..     . || |..|.          |.||....  .  .|.|||   || . .       . ... .||..  ||.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CQPLLQPSQVKSLMCQLLSGLAELHSAGFVHRDVKPANILIKGGKTLKITDFGLSRKLNSK--------HLTSK---VSS--LAYR--APELILGSNNYN
..| |....  | . |  .| . ||| ...|||    |.|.. ..| ||.||||||.. ..          ..|    .   | .|  ||| |   | . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGK

YSI--DIWSAGVIFYELCTGEKFPS--------ACSDLSQLDKIFRVTGTPSP----SSDDEKSPEPTDGDILCQLPNWRLASMLHIYPRTLEQLLTDKL
...  |.|| ||  .|..|  . |           ... .. |  .    |      |                                          
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------------F

PQELADAVEIITSMLSLNPSKRPSALELLRNPFF
.   ..  .|...    .|..||.  |.    .|
VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 91895.m00068.AA CDK 247-308 19 3e-09 25.55 In-house 252-284 (284) Show / Hide 
Range on Protein: 247-308
Range on HMM: 252-284/284
Sequence Identity: 19% (12 aa)

LCQLPNWRLASMLHIYPRTLEQLLTDKLPQELADAVEIITSMLSLNPSKRPSALELLRNPFF
...||..                             . . .|| ..|.|| || . |  |.|
VTKLPDY-----------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 91895.m00068.AA CDC2 262-308 30 4.7e-09 23.42 In-house 246-301 (301) Show / Hide 
Range on Protein: 262-308
Range on HMM: 246-301/301
Sequence Identity: 30% (17 aa)

YPRTLEQLLTDKLPQ-------ELAD--AVEIITSMLSLNPSKRPSALELLRNPFF
.||  .| |.. .|.       . .|  ..... .|| ..|.|| || | |..|.|
FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 91895.m00068.AA CDK-DD1 278-308 38 5e-08 20.23 In-house 349-379 (379) Show / Hide 
Range on Protein: 278-308
Range on HMM: 349-379/379
Sequence Identity: 38% (12 aa)

LADAVEIITSMLSLNPSKRPSALELLRNPFF
| . ...|  || |.| || ...| |  |.|
LPSFLDLIERMLTLCPKKRINTKEALQHPWF
Kinase 91895.m00068.AA STE 280-308 35 7e-06 16.89 In-house 329-359 (359) Show / Hide 
Range on Protein: 280-308
Range on HMM: 329-359/359
Sequence Identity: 35% (11 aa)

DAVEIITSMLSLNPSKRPSALELLR--NPFF
.  . |   |  .|.|||.| .||.   ||.
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 91895.m00068.AA CRK7 279-308 33 1.7e-05 14.69 In-house 314-343 (343) Show / Hide 
Range on Protein: 279-308
Range on HMM: 314-343/343
Sequence Identity: 33% (10 aa)

ADAVEIITSMLSLNPSKRPSALELLRNPFF
....     || |.|.|| .| | |. ..|
KECLDLLDKMLCLDPKKRFTAEECLQHDWF