Gene 82736.m00203 (T.vaginalis)

82736.m00203

Species: T.vaginalis
Alias: TvagK0581, 82736.m00203
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
82736.m00203.AA Protein None 346 None Fasta, JSON
82736.m00203.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of 82736.m00203.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82736.m00203.AA CMGC 15-307 19 2.5e-86 283.6 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-513/513
Sequence Identity: 19% (103 aa)

FRIIENIGQGAYGSVYKALDLLNN--------------KIVALKTVK-IFDHKQS---------MPVSFFRELKVLQSIK-----------------DSH
. ||. ||.|.|| |||. | ..|              .|||.| .|  | ..           .| . .||.| |. ..                 . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIQYFETIRSND-----------------STFISMECCDTDLQKQLSSRY---------RLSFIQ------------IKSLM------KQLLQGLN--TL
|.. .. .....                 . .. .|..|.|| . . .            ||  .            ||..|      .|.|.||.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSNG--FAHRDIKPANILLKGGSQL--------------------KIADLGLSKQILNQ-----------------------RLTSKVCALAYRAPELIL
||..  . |||.||.|||.    .|                    ||.| ||.... .                         .|. |. . |||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GSKDYT---------FSVDIWSAGVIFYELLT---------GLPFP----------AAGSEIGQIDKIFQLTGTPN---------NSETNSNEDIKLFNF
|.|.||          ..|.||.| ||.|..|            ||             |.| |..|||.. |||.         .  .  ..  . .  
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHF--N-FCKHEEEWPN

YCQLPNW----------NITSMLSSH-----------TRTLEQFLEKLIPL-----------------------------------EMQEAIPILLEMLS
. .||..          ..|. .|..            .   . ...|.|                                    . ..||  |  || 
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQ

LNPEKRPSASQLLQYDFF
..|.||..|.| || ..|
YDPDKRITAEQALQHPYF
Kinase 82736.m00203.AA S_TKc 15-307 26 1.8e-81 277.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-231/231
Sequence Identity: 26% (81 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQSMPVSFFRELKVLQSIKDSHIIQYFETIRSNDSTFISMECCDT---DLQKQLSSRYR----
..|.. ||.||.|.|||. .   ..|||.| .|          .. ||...|.. .  .|......... |. .. ||.||.   || . . .| |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQILNQRLTSKVCALAYRAPELILGSKDYTF-SVDIWSAGVIFYELL
  ..  .....|.|....|. .||.|. |||.||.||||    ..||.| ||..|.     |. .  . |.|||..     |.. ..|.|| |.|.||.|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGLP-FPAAGSEIGQIDKIFQLTGTPNNSETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLEMQEAIPILLEMLSLNPEKRPSASQLLQ
.| | ||       |....|.. |                                                  .||. ..  .|  .|||||.| ..||
CGYPPFP-------QMQMMFKKIG-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------YDFF
         .|
DEWDIKCHPWF
Kinase 82736.m00203.AA CDK 15-307 29 5.8e-81 258.75 In-house 1-284 (284) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-284/284
Sequence Identity: 29% (98 aa)

FRIIENIGQGAYGSVYKALDLLNN-----KIVALKTVKIFD-----HKQSMPVSFFRELKVLQSIKDSHIIQYFETIRSN-----------DSTFISMEC
. ..| ||.|.|| |||| |....     .||||| ...       .|  .| .  || . |. .   .|.. .. . ..            . .. .| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CDTDLQKQLSSRYRLSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQ-----LKIADLGLSKQILN--------QRLTSKVCALAYRAPEL
.|.|| | ..         ||..|.|||.||. .|||.. |||.||.|||.    .     ||||| ||..   .        . .|..|  | ||||||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

ILGSKDYT--FSVDIWSAGVIFYELLT---GLPFPAAGSEIGQIDKIFQLTGTPNNSETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPL
 ||||.|.   ..|.||.| ||.|..|   . |.    ||| |..|||.. |||. .   . ..  ..                                
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------------

EMQEAIPILLEMLSLNPEKRPSASQLLQYDFF
        |  || ..|.|| ||.| || ..|
------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 82736.m00203.AA Pkinase 15-307 27 1e-78 272.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-293/293
Sequence Identity: 27% (88 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQSMPVSFFR--ELKVLQSIKDSHIIQYFETIRSNDSTFISMECCDT-----DLQKQLS--SR
..|.. ||.|..|.|||. .  ..||||.|..|  . | ..... .|  |........  .|...... ...|.  . ||.|.      ||   .|  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YRL--SFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQL----KIADLGLSK---QILNQRLTSKVCALAYRAPELILGSKDYTFSVDIWSA
 ..  |  ..|. |.|.|.||. .||.|. |||.||.|||..   ..    ||.| ||.|      |. .|. .. . |.|||.|.|...|. .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIFYELLTG-LPFPAAG----SEIGQIDKIFQLTGTPNNSE---TNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLEMQEAIPILLEML
|.|.||.|.| .|||       . . |. .|..  |.|. ..   ..|. . . |...                    . .... ..  .|.. ..  .|
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHW-H------------------F-HWTF-HNWSEECKDFIKWCL

SLNPEKRPSASQLLQYDFF
 ..|.|||.| |.|| ..|
CKDPKKRPTAEQILQHPWF
Kinase 82736.m00203.AA CDC2 15-307 32 1.5e-66 203.35 In-house 1-301 (301) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-301/301
Sequence Identity: 32% (101 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQS--MPVSFFRELKVLQSIK-DSHIIQYFETIRSNDSTFISMECCDTDLQKQLS----SRYR
.  || || | || |||. |.  |.||||| ...         | .  ||.  |. .| .  |.. .. | .  . ..  |..| || | .     ... 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQI---LNQRLTS-KVCALAYRAPELILGSKDYTFSVDIWSAGVIFYEL
.. . .||.|.|.|||.. .|...  |||.|| |||.    ..|||| ||.. .   ... .|   |  | |||||. ||.|.|...||.|| | ||.|.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LTGLPFPAAGSEIGQIDKIFQLTGTPNNSETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLEMQ-EAIPILLEMLSLNPEKRPSAS
    |  |. .. ||| |. |||.  ||||... .. .  .|  ..   |.|. . . .   . ...   |   ...  |.| .| .|| ..|.|| || 
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVT--QLPDYKNTFPRWKPQDLSKICPNNQKK---KNQ-SCLDPEGIDLLMQMLQYDPQKRISAK

QLLQYDFF
. ||  .|
EALQHPYF
Kinase 82736.m00203.AA Ciliate-E2 15-307 19 2.4e-61 209.33 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-365/365
Sequence Identity: 19% (84 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALK---------------TVKIFDHKQSMPVSFFRELKVLQSI-----------------KDSH--IIQYFET
. .|. ||||..|||||. . ...| .|.|               ..||.  |. ..   .  ..... .                 ...|  ||...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IR--SNDSTFISMECCDT-DLQKQLSSR-----------YRLSFIQIKSLMKQLLQ---------------GLNTLHSNG-FAHRDIKPANILLKGGSQL
    .... .. || |.  ||.. . ..            ...  .|| .|||.||               .|. |||..   |||||| |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADLGLSKQILNQ---------------------------------RLTSKVCALAYRAPELILG--------SKDYTFSVDIWSAGVIFYELLTG-LP
||.|.||||.. ..                                    . .. . | ||| . |        .|.|....||||.|||.||.|.| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPAAGSEIGQIDKIFQLTGTPNNSETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLEMQ---------------------EAIPILLE-
|                                                       ..| ... | .  .                     |.. ..   
F-------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---MLSLNPEKRPS-ASQLLQYDFF
   ||  .||||.. ..|.|.  .|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase 82736.m00203.AA CDK-DD1 15-229 34 1.1e-60 185.83 In-house 1-219 (379) Show / Hide 
Range on Protein: 15-229
Range on HMM: 1-219/379
Sequence Identity: 34% (76 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQSMP---VSFFRELKVLQSIKDSHIIQYFETIRSNDSTFISMECCDTDLQKQLSSRY-RLSF
. ||. .||| ||||.||   .   .|||| .|        |   ...   |. .  |   |.| .| ..  |.   . .|    || | .| .   .| 
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEPKVECKYLMQLRHCKNI--VHLIDHF-YNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSL

IQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQILN---QRLTSKVCALAYRAPELILGSKDYTFSVDIWSAGVIFYELLTGL
 .||  ..||| |.| .|..|  |||||||| |      |||.|.|..  . .     . ..|  | ||.||| .||  |   .|.|| | |  |..|. 
PCIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNF

PFPAAGSEIGQIDKIFQLTGTP
 . |  .|  | . |. | |.|
YMFAGSNEQQQLELICKLCGCP
Kinase 82736.m00203.AA MAPK 15-307 28 2.7e-57 196.65 In-house 1-328 (328) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-328/328
Sequence Identity: 28% (98 aa)

FRIIENIGQGAYGSVYKALDLL------NNKIVALKTVK-IFDHKQSMPVSFFRELKVLQSI-KDSHIIQYFETIRSN----DST-------FISMECCD
..|...||||||| | .| | .      ..|.||.| .   |......    .||.| |. . ..  ||  .. ..      ...        | || ..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK-RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME

TDLQKQLSSRYRLSFIQIKSLMKQLLQG--LNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQILNQ----------------RLTSKVCALAYRA
|||.. . |.  || . |...| |.| |  |  .|| .  |||.||.|||.    .|||.| ||. .| ..                 .|  |    |||
TDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PELILG--SKDYTFSVDIWSAGVIFYELLT-GLPFPAAGSEIGQIDKIFQLTGTPNNSETNSNEDIKLFNFYCQLP-NWNITSMLSS---HTRTLEQFLE
||..|.  ...|| .||.||.| || |.|| . |.    . | |. .|....|||   |           |..... . .  ....|   ....  . .|
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEE-----------FIQCICMSEHARNYIQSLGNLPKYPKKPWE

KLIP----LEMQEAIPILLEMLSLNPEKRPSASQLLQYDFF
|..|    .   .||  |  || ..|.|| .. . ||  .|
KMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 82736.m00203.AA CDK-Unclassified 15-230 32 6.7e-57 185.66 In-house 1-259 (324) Show / Hide 
Range on Protein: 15-230
Range on HMM: 1-259/324
Sequence Identity: 32% (83 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQ----------SMPVSFFRELKVLQSIKDSHII-----QYFETIRS--------NDSTFISM
 |... .|.|..|.|.||.|.. .|.|| | . .   |             ...  ||...||  ..  ||      |  . .|        . | .. |
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVM

ECCDTDLQKQLSS-RYRLSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGS-----QLKIADLGLSKQIL--------------NQRLTSKVC
|  . ..  || . || ||  ||.  |.|.| |.. ||.|.. ||||||.||..          ||||| |..                  .|  .. | 
EYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVS

ALAYRAPELILGSKDYTFSVDIWSAGVIFYELLTGLPFPAAGSEIGQIDKIFQLTGTPN
   |||||| .||| |.  |||||.| |. |.. | |  .  .|| |. .||.. |||.
TRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPC
Kinase 82736.m00203.AA ULK 15-208 24 6.6e-55 188.72 In-house 1-250 (324) Show / Hide 
Range on Protein: 15-208
Range on HMM: 1-250/324
Sequence Identity: 24% (62 aa)

FRIIENIGQGAYG-SVYKALDLLN---NKIVALKTVKIF--DHKQSMPV------SFFRELKVLQSIK---DSH--IIQYFETIRSNDS--TFISMECCD
. ... .|.|..|  |||. .  .   |..|| | . ..    |...        .. .| .... .|     .  |.....  .. ..  ..| || |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

T-DLQKQLSSRYRLSFIQ----------IKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGS------------QLKIADLGLSKQILN-----QRLT
  ||.. .  . .|.. .          ... .||...|.  ||...  ||||||.|||.. |             .||||| |..|.. |     | ..
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SKV------CALAYRAPELIL---GSKDYT-FSVDIWSAGVIFYELLTGLP
. |      .   | ||...    . |.|. . .|||| |.||||.|.| .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKY
Kinase 82736.m00203.AA Ciliate-E2-Unclassified 15-307 21 1.5e-54 187.57 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-352/352
Sequence Identity: 21% (83 aa)

FRIIENIGQGAYGSVYKALDLLNNKIV----ALKTVKIFDHKQSMPVSFFRELK---------------------VLQSIKDSHIIQYFETIRSNDSTFI
..||. ||||..|.|||. .  ..  .     .| ..|.. || | .     ..                      |..... .|. .|.. .. .  .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

SMECC------------------DTDLQKQLSSRYRLSFIQIK-----SLMKQLLQGLNTLHSNG-FAHRDIKPANILL-KGGS--QLKIADLGLSKQIL
 || |                    || ... .| ...  |.|      ...|.||||. ||... . |||||| |||. ..|.  ..||.|.|.||.. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------------NQRLTSKVCALAYR----APELILGSKDYT---FSVDIWSAGVIFYELLTG-LPFPAAGSEI---------------GQIDKI
                 .|....... . |     |||.. | . ..   ...|||| |||.||.|.| .||..  .|.                ....|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

FQLTGTPNNSETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLEMQEAIPILLE-----MLSLNPEKRPSASQLLQYDFF
.|     ....  .                                    ||   ..    ...     ||  ||.||....|.|.  .|
KQKNIQFPKFPWQQ------------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82736.m00203.AA CRK7 15-230 30 1.1e-51 176.45 In-house 1-273 (343) Show / Hide 
Range on Protein: 15-230
Range on HMM: 1-273/343
Sequence Identity: 30% (82 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDH---KQSMPVSFFRELKVLQSIKDSHIIQYFETIRSN----------DSTFISMECCDTDLQKQ
...|. || | || |||| .. ....|||| |.  .    |   |.   || |.|.. .   |..  | . .            |..   |  | ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LSSR--YRLSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQILN----QRLTSKVCALAYRAPELILGSKDY--------
| |      |  |.|..||||| |.. .| ..| ||||| .|||.    ..||||.||          . .| .|  | ||.||| || . |        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------TFSVDIWSAGVIFYELLTGLPFPAAGSEIGQIDKIFQLTGTPN
                              . ..|.|| | |. ||.|. |   .  |..|..||... |.||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPN
Kinase 82736.m00203.AA TyrKc 15-307 22 1e-13 -0.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-307
Range on HMM: 1-280/280
Sequence Identity: 22% (75 aa)

FRIIENIGQGAYGSVYKALDLLNNKIVALKTVKIFDHKQSMPVSFFRELKVLQSI--KDSHIIQYFETIRSN-------DSTFISMECCDT-DLQKQL-S
 . .. .| ||.| |||.        || |..|           | ||.... ..  .  .|.. .  ...        .  .| || ..  ||.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SRYRLSFIQIKSLMKQLLQGLNTLHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQILNQ-------RLTSK----VCA--LAYR--APELILGSKDYT
.| .|.  .  | . |  .| . |||... |||.   |.|.. . . ||.| |||. | .           .|     .   | .|  ||| |  .| .|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FT

FSVDIWSAGVIFYELLT--GLPFPA------AGSEIGQIDKIFQLTGTPNN----SETNSNEDIKLFNFYCQLPNWNITSMLSSHTRTLEQFLEKLIPLE
.  |.|| ||  .|..|  . | |         .|. .  |       | |    |                                   |     | |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-----------------------------------F--VCCPDE

MQEAIPILLEMLSLNPEKRPSASQLLQYDFF
| .   | ..    .||.||. |..  ...|
MYQ---IMKQCWHEDPEDRPTFSEI--HECF
Kinase 82736.m00203.AA CRK7 262-307 38 1.3e-07 22.09 In-house 297-343 (343) Show / Hide 
Range on Protein: 262-307
Range on HMM: 297-343/343
Sequence Identity: 38% (18 aa)

TRTLEQFLEKLIPLEM-QEAIPILLEMLSLNPEKRPSASQLLQYDFF
.| .|.| ..  |  | .|.   | .|| |.|.|| .|.. || |.|
RRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 82736.m00203.AA CDK-Unclassified 283-307 24 2e-06 17.14 In-house 300-324 (324) Show / Hide 
Range on Protein: 283-307
Range on HMM: 300-324/324
Sequence Identity: 24% (6 aa)

ILLEMLSLNPEKRPSASQLLQYDFF
... |....| .|......||   |
CEFQMVMYQPYNRWKCMEILQHPWF
Kinase 82736.m00203.AA Pkinase_Tyr 127-210 33 3e-06 21.94 Pfam 127-217 (270) Show / Hide 
Range on Protein: 127-210
Range on HMM: 127-217/270
Sequence Identity: 33% (31 aa)

LHSNGFAHRDIKPANILLKGGSQLKIADLGLSKQI-----L-NQRLTSKVCALAYRAPELILGSKDYTFSVDIWSAGVIFYELLT-G-LP-FP
|.|... |||.   |.|.. . . ||.| ||.. |        .|  .| .     ||| |  .| .|   |.|| ||  .|..| |  | .|
LESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYP
Kinase 82736.m00203.AA Pkinase_Tyr 15-77 23 1.7e-05 19.27 Pfam 1-69 (270) Show / Hide 
Range on Protein: 15-77
Range on HMM: 1-69/270
Sequence Identity: 23% (16 aa)

FRIIENIGQGAYGSVYKALDL----LNNKIVALKTVKIFDHKQS-MPVSFFRELKVLQSI-KDSHIIQY
 .... .|.||.|.|||.        ..  || |..|   ...  .  .|.||.|.. .. .  .|...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRL
Kinase 82736.m00203.AA CDK-DD1 281-307 33 6.8e-05 10.37 In-house 353-379 (379) Show / Hide 
Range on Protein: 281-307
Range on HMM: 353-379/379
Sequence Identity: 33% (9 aa)

IPILLEMLSLNPEKRPSASQLLQYDFF
. ... || |.| || .. . ||  .|
LDLIERMLTLCPKKRINTKEALQHPWF