Gene 88945.m00103 (T.vaginalis)

88945.m00103

Species: T.vaginalis
Alias: 88945.m00103, TvagK0661
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
88945.m00103.AA Protein None 431 None Fasta, JSON
88945.m00103.kin_dom Protein Kinase Domain None 322 None Fasta, JSON

Protein domain

Protein domains of 88945.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88945.m00103.AA DYRK 71-392 30 1.5e-81 277.25 In-house 1-320 (320) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-320/320
Sequence Identity: 30% (100 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQRSLFEGIGQDDPPL
.......| |... | ||.        ||.||..|.. .  ... || | . . .. | | | |. .    |   .| |.| .||. .|.| . .     
YEILEYIGKGSFGQVVKCWDH-KTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQG

V-LLSTIRTICTQLLKALNFVHNN-GIIHCDVKPDNIMYSNE-SNDNILLIDFGSATNQPPQIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAELY
.  |. .|... |.|..| | |.|  ||||| ||.|||  .. .. .| .|||||..    .| .||||||||.||..||.||. .||.||.||| |||.
FFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELF

LDFAIFACDSEIDSIHSMVGLLGPIDQSIIAKS--RGWWKFYDMTPEGYTLKMDPIDVLMNRHLYHETVFE---VIGVRPLHQMLLDHFPLTSDEEFETL
.   .|. ..| | .  .. .||.. . .| |.  |   ||.|       .... .|   ..    .. ..   ..  |  . .. .. .. .  .    
TGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC------FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDD

NTFNHFVHSLLNFDPDQRLTAAQALQHPFI
  |..|.  .|..||..|.|..||||||..
HQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 88945.m00103.AA CMGC 71-392 18 5.1e-77 252.42 In-house 1-513 (513) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-513/513
Sequence Identity: 18% (98 aa)

FRVIDVLGNGTYSYVYKCQV-------------VTEPTRFVALKILKNQPQYRATGI-------------AEIMIHQQMQKAPDMDG-----------KQ
. .|...| |||. ||||.               .|  ..||.|..||.. |  ..               ||.| ....|. |  .           . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

HVGNPISTFEING-----------------HICMVMDLLQRSLFEGIGQDDP--------PL------------------VLLSTIRTICTQLLKALN--
.. . .  |  ..                 |...|..... .|.. | .  .        ||                   ..  || .. |.|..|.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

FVHNNG--IIHCDVKPDNIMYSNE------------------SNDNILLIDFGSAT--NQPP----------------------QIGQYIQSRFYRSPEI
. | ..  |||.| || ||. ...                  .|... ..|||.|.  ....                      .. .|...|.||.|||
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

MLGLP----------YDQKIDIWSVGCIAAELYLD--------FAIFACDSE-----------IDSIHSMVGLLGPIDQSIIAK----------SRGWWK
.|| .          |...||.|||||| ||.|.           .|  .||           || .. .. .||... ..| |          .. | .
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

FYD-------------------MTPE-------GYTLKMDPIDVLMNRHLYHET---------VFEVIGVRPLHQMLLDHFPLTSDEEFE----------
. .                   ...        . .... |   . | .  | .         ||    .    .           |.|           
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IY---E-----------EKFKSHKFNHQFKR

--TLNTFNHFVHSLLNFDPDQRLTAAQALQHPFI
      . ...  .| .|||.|.||.||||||..
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 88945.m00103.AA S_TKc 71-392 20 1e-61 212.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-231/231
Sequence Identity: 20% (68 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQR---SLFEGIGQDD
.......| |... ||||. .    | ||.||.|       . . || |...        .  .. . . .|.  .|..|||...     .||. | .  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

PPL----VLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDNILLIDFGSATNQPPQIGQYIQSRFYRSPEIMLGLPYDQ-KIDIWSVGCI
..         ..| .. |...||.. |..||||.|.||.||. ..    .| ..|||.|.        .. ...|..||..   .|.  |.|.||.|||
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

AAELYLDFAIFACDSEIDSIHSMVGLLGPIDQSIIAKSRGWWKFYDMTPEGYTLKMDPIDVLMNRHLYHETVFEVIGVRPLHQMLLDHFPLTSDEEFETL
 .|..     |    ... .  ..|                                                                           
LYEMLCGYPPFP---QMQMMFKKIG--------------------------------------------------------------------------S

NTFNHFVHSLLNFDPDQRLTAAQALQ-------HPFI
  . .|.  .|..||..|.|| .|||       ||..
PEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88945.m00103.AA DYRK1 71-392 30 1.8e-48 167.39 In-house 1-321 (321) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-321/321
Sequence Identity: 30% (98 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQRSLFEGIGQDDPPL
. ..  .| | .  | |     |   .||.||.||.  .      || .   | |. | . | .. .    |    |.|.|..||   |.. .   .   
YEIDSLIGKGSFGQVVKAYDHQE-QEYVAIKIIKNKKPFYNQAQIEIRLLELMNKH-DKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRG

VLLSTIRTICTQLLKALNFVHNN--GIIHCDVKPDNIMYSNESNDNILLIDFGSATNQPPQIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAELYL
| |  .| .  |...|| |.      |||||.||.||.  |     | .|||||. .    | ||||||||||||..||..|| .||.||.|||  |.  
VSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHT

DFAIFACDSEIDSIHSMVGLLGPIDQSIIAKSRGWWKFYDMTPEGYTLKMDPIDVLM-NRHLYHETVFEVIGVRPLHQMLLDHFPLTSDEEFETLNTFNH
   .|.  .|.| .. .|  ||   . .| ..    |... .|.. .      | .  ...  .  . |..||.             .    |    |  
GEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCTRKLHEILGVE--TGGPGGRRKGEPGHSVEDYLKFKD

FVHSLLNFDPDQRLTAAQALQHPFI
 .. .|..|| ||.|  .||||.|.
LIKRMLQYDPKQRITPYYALQHSFF
Kinase 88945.m00103.AA DYRK2 71-307 32 1.9e-47 152.19 In-house 1-236 (318) Show / Hide 
Range on Protein: 71-307
Range on HMM: 1-236/318
Sequence Identity: 32% (77 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQRSLFEGIGQDDPPL
. .  |.| | .  | ||        .||.|.. |.  .  .   || | . . .  | |.   .      |   .|.|.. .||. .| | | .  .  
YEILEVIGKGSFGQVVKC-YDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQ-DKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQG

VLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDNILLIDFGSATNQPP-QIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAELYLD
  |. .|  . ..|..|.| | | ||||| || ||.   .   .| .||||| .   . .|  ||||||||.||. ||..|.  ||.|| |||.||||  
FSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTG

FAIFACDSEIDSIHSMVGLLGPIDQSIIAKSRGWWKFY
. .|. . | | .  |  .||  ..... .. .  .|.
YPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFR
Kinase 88945.m00103.AA HIPK 71-392 29 5e-47 145.85 In-house 1-329 (329) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-329/329
Sequence Identity: 29% (97 aa)

FRVIDVLGNGTYSYVYKCQV-VTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQRSLFEGIGQDDPP
. |...|| ||.  | ||    |.    ||.|||||.| |   |  |. | . ...  . |   |.      |.   |.|.| ..|   |..   |    
YEVLEFLGRGTFGQVVKCWKRGTN--EMVAIKILKNHPYYARQGQIEVSILHCLSQE-NAD-EYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFM

LVLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESND--NILLIDFGSATNQPPQIGQ-YIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAEL
   |  ||.|  | |.||    . |.|| | ||.|||   ..     .  ||||||      . . |.|||.|| |||.||||. ...|.|| ||. |||
PLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAEL

YLDFAIFACDSEIDSIHSMVGLLGPIDQSIIAKSRGWWKFY----DMTPEGYTLKM---DPIDVLMNRHLYHETVFEVIGVRPLHQMLLDHFPLTSDEEF
.|    .   .| | |  .    .   .... . .   .|.    ..  . . ||       ....        .| ..   |   ||.|  .     | 
FLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKYIFNCLDDMPEVNMLVDPERQDYRVEK

ETLNTFNHFVHSLLNFDPDQRLTAAQALQHPFI
     | |    ..  |...|.| ..||.|||.
IDRREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase 88945.m00103.AA YAK 71-290 35 1.9e-44 148.7 In-house 1-222 (347) Show / Hide 
Range on Protein: 71-290
Range on HMM: 1-222/347
Sequence Identity: 35% (79 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGKQ---HVGNPISTFEINGHICMVMDLLQRSLFEGIGQDD
. | |.|| ||.  | |||        .| |..|| . |   .. || | .   .  | ..|    |. . .  |    | |.|  .|  .|.| . |  
YIVLDMLGQGTFGQVVKCQNC-DTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNK

PPLVLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDNILLIDFGSATNQPPQIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAELY
      . ||.  .| | ..    |  ||||| || |||  .     | .|||||.      .  |||.|.||||||... .|   || || ||| |||.
FCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELF

LDFAIFACDSEIDSIHSMVGLLG
|   ||   || . |   .  ||
LGLPIFPGNSEYNQIKRIIDMLG
Kinase 88945.m00103.AA PRP4 71-267 37 2.7e-39 136.85 In-house 1-199 (320) Show / Hide 
Range on Protein: 71-267
Range on HMM: 1-199/320
Sequence Identity: 37% (76 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKA-PDMDGKQHVGNPISTFEINGHICMVMDLLQRSLFEGI---GQD
.||.   | | .| | .|.  |     || ||. | .  . ||  |. | | .  |  | . | |.     .|.   |.|.|   .  .| | .   |.|
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

DPPLVLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDNILLIDFGSATN-QPPQIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAE
.     |  .|    ||. ||    ...|.| |.|||||.  |||.  . ..|||||   .   |  | .|||||.|||..| |||  ||.|||||  .|
VG--LHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILV-NESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYE

LY
||
LY
Kinase 88945.m00103.AA Pkinase 71-292 23 9.7e-35 123.92 Pfam 1-234 (293) Show / Hide 
Range on Protein: 71-292
Range on HMM: 1-234/293
Sequence Identity: 23% (58 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIA-----EIMIHQQMQKAPDMDGKQHVGNPISTFEINGHICMVMDLLQR-----SLF
.... ..| |... ||||. . ..   ||.||.| . .     ..     || |.. ..         ..   . .|| ..||.|||....      .||
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

EGIG-QDDPPL-VLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDN---ILLIDFGSA----TNQPPQIGQYIQSRFYRSPEIML-GLPY
. |  ... ..     ... ...|.|..|.. |..||||.|.||.||... . ...   . ..|||.|    .   .    .  ...|..||. . | .|
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

DQKIDIWSVGCIAAELYLDFAIFACD----SEIDSIHSMVGLLGPI
..|.|.||.||| .|...   .|  .    . .| .. ..  .||.
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP
Kinase 88945.m00103.AA RCK 174-290 35 1.8e-34 106.55 In-house 103-231 (298) Show / Hide 
Range on Protein: 174-290
Range on HMM: 103-231/298
Sequence Identity: 35% (46 aa)

ST--IRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNE-------SNDNILLIDFGSA---TNQPPQIGQYIQSRFYRSPEIMLGL-PYDQKIDIWSVG
..  |. |  |.|..|.. |..|. | |.|| |||....       ..|.| ..|||..    ..||    |. .| ||.||. |    |. ..|||.||
NQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPP-YTDYVSTRWYRAPECLLRCTYYNSPMDIWAVG

CIAAELYLDFAIFACDSEIDSIHSMVGLLG
||..|||  .. |.  |||| |. ..  .|
CIMYELYMLRPLFPGSSEIDQIFKICKVMG
Kinase 88945.m00103.AA CLK 71-205 28 2.7e-29 84.41 In-house 1-145 (350) Show / Hide 
Range on Protein: 71-205
Range on HMM: 1-145/350
Sequence Identity: 28% (41 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIM-IHQQMQKAPDMDGKQH--VGNPISTFEI-NGHICMVMDLLQRSLFEGIGQD
. ....|| || . |..|.      ..||||| .|  .||    .||  | .. ... | ..|    ..  ...|.  .||||.|..|. .|... .   
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

D-------PPLVLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNI
         |.  ...|| .  ||..|..| | ....| | || ||
NSKMPNKYIPYP-IDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENI
Kinase 88945.m00103.AA CDK 172-290 31 1.5e-26 81.86 In-house 107-242 (284) Show / Hide 
Range on Protein: 172-290
Range on HMM: 107-242/284
Sequence Identity: 31% (43 aa)

LLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDN---ILLIDFGSATNQP-------PQ--IGQYIQSRFYRSPEIML-GLPYD--QKIDI
... |...  |||..|.. | |.|.| | || ||...|  .     . . ||| |           |.      .  . ||.||. |    |.    ||.
YMD-IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDM

WSVGCIAAELYL---DFAIFACDSEIDSIHSMVGLLG
|||||| ||...     ..| .||||| ..    ..|
WSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG
Kinase 88945.m00103.AA CLK 212-301 38 2.8e-21 59.9 In-house 183-276 (350) Show / Hide 
Range on Protein: 212-301
Range on HMM: 183-276/350
Sequence Identity: 38% (36 aa)

NDNILLIDFGSAT---NQPPQIGQYIQSRFYRSPEIMLGLPYDQKIDIWSVGCIAAELYLDFAIFACDSEIDSIHSMVGLLG-PIDQSIIAKSR
|..| .|||||||      .     ...| || ||. |||.. |. |.||.|||  |||. |  |   ....    |  ..| || |. | ..|
NTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTR
Kinase 88945.m00103.AA CDK 367-392 42 3.7e-10 28.53 In-house 259-284 (284) Show / Hide 
Range on Protein: 367-392
Range on HMM: 259-284/284
Sequence Identity: 42% (11 aa)

HFVHSLLNFDPDQRLTAAQALQHPFI
..  ..| .||..|..| ||||||. 
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 88945.m00103.AA RCK 369-392 50 5.2e-10 27.66 In-house 275-298 (298) Show / Hide 
Range on Protein: 369-392
Range on HMM: 275-298/298
Sequence Identity: 50% (12 aa)

VHSLLNFDPDQRLTAAQALQHPFI
.. .|. ||. | ||.||||||..
MEKMLQWDPQKRITAQQALQHPYF
Kinase 88945.m00103.AA DYRK2 365-392 42 6.8e-10 28.02 In-house 291-318 (318) Show / Hide 
Range on Protein: 365-392
Range on HMM: 291-318/318
Sequence Identity: 42% (12 aa)

FNHFVHSLLNFDPDQRLTAAQALQHPFI
|. |.   .  ||..|.|..|||.||.|
FIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase 88945.m00103.AA Pkinase 350-392 24 1.2e-09 35.2 Pfam 232-293 (293) Show / Hide 
Range on Protein: 350-392
Range on HMM: 232-293/293
Sequence Identity: 24% (15 aa)

HFPLTSDEEFETL-------------------NTFNHFVHSLLNFDPDQRLTAAQALQHPFI
. || .|.. .                      .. .|. ..|..|| .|.||.|.||||..
GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88945.m00103.AA YAK 365-392 46 3.3e-09 27.03 In-house 320-347 (347) Show / Hide 
Range on Protein: 365-392
Range on HMM: 320-347/347
Sequence Identity: 46% (13 aa)

FNHFVHSLLNFDPDQRLTAAQALQHPFI
| .|.  ||. .|  | .. || |||||
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase 88945.m00103.AA CLK 369-392 45 3.7e-09 22.86 In-house 327-350 (350) Show / Hide 
Range on Protein: 369-392
Range on HMM: 327-350/350
Sequence Identity: 45% (11 aa)

VHSLLNFDPDQRLTAAQALQHPFI
.  .| .|| .|.|...|||||| 
IRKMLEYDPSKRITCKDALQHPFF
Kinase 88945.m00103.AA PRP4 355-392 31 2e-06 19.33 In-house 283-320 (320) Show / Hide 
Range on Protein: 355-392
Range on HMM: 283-320/320
Sequence Identity: 31% (12 aa)

SDEEFETLNTFNHFVHSLLNFDPDQRLTAAQALQHPFI
.... . .  |  .   .|  ||  | |  .||.||||
PEDQMKKVHQFKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase 88945.m00103.AA CDK 71-104 28 6e-06 14.76 In-house 1-38 (284) Show / Hide 
Range on Protein: 71-104
Range on HMM: 1-38/284
Sequence Identity: 28% (11 aa)

FRVIDVLGNGTYSYVYKCQVVT----EPTRFVALKILK
.  .. .| |||  |||..       .. ..|||| ..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIR
Kinase 88945.m00103.AA TyrKc 71-392 11 0.000106 -146.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 71-392
Range on HMM: 1-280/280
Sequence Identity: 11% (43 aa)

FRVIDVLGNGTYSYVYKCQVVTEPTRFVALKILKNQPQYRATGIAEIMIHQQMQKAPDMDGK--QHVG--NPISTFEIN-------GHICMVMDLLQR-S
 . ...||.| .  |||..      . || | ||.          . .... ..    |     .|    . .             . ...|| .    .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA--------REDFMREARI---MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

LFEGIGQDDPPLVLLSTIRTICTQLLKALNFVHNNGIIHCDVKPDNIMYSNESNDNILLIDFGSATNQPPQ-----IGQYI------QSR-----FYRSP
| . .    |  . ...   .|.|  .  .. | ...|| |    |......    .   ||| . .          ..|.      ...        .|
LKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EIMLGLPYDQKIDIWSVGCI-------AAELYLD--------FAIFACDSEIDSIHSMVGLLGPIDQSIIAKSRGWWKFYDMTPEGYTLKMDPIDVLMNR
| .    .  | |.|| |          .. | .        . ....  . .    .   . |.                                   
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMS----------------------------------

HLYHETVFEVIGVRPLHQMLLDHFPLTSDEEFETLNTFNHFVHSLL----NFDPDQRLTAAQALQHPFI
                               |    .    ....     ..||..| | ..   | ..
-------------------------------F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 88945.m00103.AA APH 194-228 24 0.000606 14.33 Pfam 171-207 (248) Show / Hide 
Range on Protein: 194-228
Range on HMM: 171-207/248
Sequence Identity: 24% (9 aa)

GIIHCDVKPDNIMYSNESNDNIL--LIDFGSATNQPP
...|.|..|.|.|..  .... .  .||.. |.  .|
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase 88945.m00103.AA RCK 71-89 47 0.020712 3.13 In-house 1-19 (298) Show / Hide 
Range on Protein: 71-89
Range on HMM: 1-19/298
Sequence Identity: 47% (9 aa)

FRVIDVLGNGTYSYVYKCQ
  .|. || |||. | | |
YQIIKQLGDGTYGCVMKAQ