Gene 86278.m00103 (T.vaginalis)

86278.m00103

Species: T.vaginalis
Alias: TvagK0656, 86278.m00103
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
86278.m00103.AA Protein None 373 None Fasta, JSON
86278.m00103.kin_dom Protein Kinase Domain None 327 None Fasta, JSON

Protein domain

Protein domains of 86278.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86278.m00103.AA DYRK 44-370 33 7.9e-84 284.8 In-house 1-320 (320) Show / Hide 
Range on Protein: 44-370
Range on HMM: 1-320/320
Sequence Identity: 33% (111 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSVDLYQVLKYRN
..||...| | ||.|...     |       |.|| .... ...||  ||.| ... ..   .|..... |   | ..||.||| |||| .||..|| ..
YEILEYIGKGSFGQVVKCW----DHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNH

FKGL-SISLVRNLLKQLLQDLVVLKKI-GIIHGDIKPENIMSVN--GNNAIKLIDFGSAKTEGNFSDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVAI
|.|. |..|||  ..|.|. |..|.|   |||.|.|||||| ..  ....||.|||||.  |.     | |||.|||||| | .||.|..|.||. |.  
FQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILA

EMFIANPIFAGQNELYLLQLISQYVSQIPISMIRSS--PRRKDFFNHDNTLKTLNQYCYENGIQVPQFQPYLIYNTISELIMKYPIARANKQGDFLQKEM
|.|. .|.|.|.||  .|..| ..   .|  ||...  .|.. ||.      .  ..| |.  |    . | ..... ... ..     .. .| ...  
ELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-----FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ--

TRREHFLKLIQKMLIIDPKLRPTPEKCLEDPFF
. .. |. .|.|.|..||. |.||.  |. |.|
CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 86278.m00103.AA CMGC 44-370 17 1.4e-72 237.53 In-house 1-513 (513) Show / Hide 
Range on Protein: 44-370
Range on HMM: 1-513/513
Sequence Identity: 17% (90 aa)

FTILSPLGNGQFGNVFQVLCMSAD----------MEAPVVYAMKITKSQQHYQDQAN-------------HEIEIHRRIQEKIAAED-----------RK
..|....| | .|.|..  .   .          .|   ..|.|. |... |..||               ||.| ......  . .           ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

YIITMIMAFEYHN-----------------HVCIVSELLSVDLYQVLKYRN--------------------------FKGLSISLVRNLLKQLLQDLV--
.|....  | ..|                 |...| |..  ||||..|  .                           | ..| ..|   .|.|. |   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

VLKKIG--IIHGDIKPENIMSVNGNNA-------------------IKLIDFGSAKTEGNF------------------------SDFYFQSRYYRAPEV
 . . .  ||| |.|||||.  . .                     .|..|||.|. ...                            | ..|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

VLNLP----------YDYKVDVWSVACVAIEMFIA--------NPIFAGQNE-----------LYLLQLISQYVSQIPISMIRS-------SPRRKDFFN
 |. .          |....|.|||.|.  ||.           |.| |..|           .  |..| .    .. .||..       ... ....|
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

HDN--------------TLKTLNQYCYENGIQV---PQFQPYLIYNTISELIMKYPIARANKQGDFLQKEMTRR---------------------EHFLK
. .              | ..   . . | ||     . .|.   . .   . .    . ||.    .    ..                     . .. 
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKK----AMVF-NWIYEEKFKSHKFNHQFKRKCCDPQAID

LIQKMLIIDPKLRPTPEKCLEDPFF
|..|||..||. |.|.| .|. |.|
LLKKMLQYDPDKRITAEQALQHPYF
Kinase 86278.m00103.AA DYRK1 44-370 31 5.2e-60 205.69 In-house 1-321 (321) Show / Hide 
Range on Protein: 44-370
Range on HMM: 1-321/321
Sequence Identity: 31% (104 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSVDLYQVLKYRN
. | |..| | || | .      | .     |.|| | .. . .||  || .   .  |  .|.. ||...   | . ||.|.| ||||  || .|.  .
YEIDSLIGKGSFGQVVKAY----DHQEQEYVAIKIIKNKKPFYNQAQIEIRLL-ELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTH

FKGLSISLVRNLLKQLLQDLVVLK--KIGIIHGDIKPENIMSVNGN-NAIKLIDFGSAKTEGNFSDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVAIE
|.| |. |.| . .|... |. .    . ||| |.|||||. .|    |||.|||||.   |.    | |||.||.|||.|...|| ..|.||. |. .|
FRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVE

MFIANPIFAGQNELYLLQLISQYVSQIPISMIRSSPRRKDFFNHDNTLKTLNQYCYENGIQVPQFQPYLIYNTISELIMKYPIARANKQGDFLQKEMTRR
| .  |.|.|.||.  .. |   .   |  || ..|. . .|..|.   .  .   .   .  ..    . . .          |..  |  ..  .   
MHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCTRKLHEILGVETGGPGGRRKGEPGHSVEDYL---

EHFLKLIQKMLIIDPKLRPTPEKCLEDPFF
 .|  ||..||. ||| | || . |. .||
-KFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase 86278.m00103.AA S_TKc 44-370 20 9.5e-58 199.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-370
Range on HMM: 1-231/231
Sequence Identity: 20% (70 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSV---DLYQVLK
..|| ..| | || |...   .       ..|.|| |      ...  ||.|...        . ..|.... .|.  .|...| |...    ||....|
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK

YRNFKG----LSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVNGNNAIKLIDFGSAKTEGNFSDFYFQSRYYRAPEVVLNLPYDY-KVDVWSVA
 |. .|    ..   .| ...|... |  . . |||| |.|||||.  .    ||..|||.|.      . .  ...|.||||.   .|.. |.|.||. 
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

CVAIEMFIANPIFAGQNELYLLQLISQYVSQIPISMIRSSPRRKDFFNHDNTLKTLNQYCYENGIQVPQFQPYLIYNTISELIMKYPIARANKQGDFLQK
|. .||.   | |   ..  ....|                                                                           
CILYEMLCGYPPFP--QMQMMFKKIG--------------------------------------------------------------------------

EMTRREHFLKLIQKMLIIDPKLRPTPEKCLE-------DPFF
     . .. .|.|.|  ||. |||  ..|.       .|.|
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86278.m00103.AA DYRK2 44-253 37 3.3e-56 181.14 In-house 1-207 (318) Show / Hide 
Range on Protein: 44-253
Range on HMM: 1-207/318
Sequence Identity: 37% (79 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSVDLYQVLKYRN
..||. .| | || |. ..    |       | |.   .. .  ||  ||.|  .| ..        .. |   | . ||.||. ||||..||  .| ..
YEILEVIGKGSFGQVVKCY----DHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQ-DKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNH

FKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIM-SVNGNNAIKLIDFGSAKTEGNFSDF-YFQSRYYRAPEVVLNLPYDYKVDVWSVACVAIEM
|.|.| .|||   ...|| |. |.|  |||.| |||||.    . . ||.|||||   |    .. | |||.|||||| | ..|.  .| ||  |.. |.
FQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAEL

FIANPIFAGQNE
..  |.|.| ||
YTGYPLFPGENE
Kinase 86278.m00103.AA HIPK 44-370 30 3.1e-53 165.76 In-house 1-329 (329) Show / Hide 
Range on Protein: 44-370
Range on HMM: 1-329/329
Sequence Identity: 30% (104 aa)

FTILSPLGNGQFGNVFQVLCMS-ADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSVDLYQVLKYR
. .|  || | || |  | |   .  |   . |.|| | .  |  |   |..| ...... | |    .. .   |. .||.|.| |.|   ||. .|  
YEVLEFLGRGTFGQV--VKCWKRGTNE---MVAIKILKNHPYYARQGQIEVSILHCLSQENADE--YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQN

NFKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVNGNNA---IKLIDFGSAKTEGNF-SDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVA
.|  | .  .| .|.| |  |. ||..|.|| |.|||||| |        .| ||||||    .   . | |||||||||..| ||.  ..|.||  || 
KFMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVI

IEMFIANPIFAGQNELYLLQLISQYVSQIPISMIRSSPRRKDFFNHDNT-------LKTLNQYCYENGIQVPQFQPYLIYNTISELIMKYPIARANKQGD
 | | . | . | .|  .   |.|       ... .  . . ||..|         ||.....  . ...  . . | |.| .  .. .  .    .. |
AELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKY-IFNCL-DDMPEVNMLVDPERQD

FLQKEMTRREHFLKLIQKMLIIDPKLRPTPEKCLEDPFF
.. . . ||| | ..  ||. .|.. | || . |. || 
YRVEKIDRRE-FVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase 86278.m00103.AA YAK 44-253 38 3.5e-51 171.95 In-house 1-210 (347) Show / Hide 
Range on Protein: 44-253
Range on HMM: 1-210/347
Sequence Identity: 38% (82 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAEDRK---YIITMIMAFEYHNHVCIVSELLSVDLYQVLK
. .|  || | || |  | |   | .   . | |. |. | |  ||  || | |   ...  ..      |. |.  | . || |.| |.||. ||  ||
YIVLDMLGQGTFGQV--VKCQNCDTNE--LFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLK

YRNFKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVN-GNNAIKLIDFGSAKTEGNFSDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVAI
  .|.|.|..|.|  .|| |  ..||.   ||| | ||||||  .    .||.|||||.  |      | |.|.||.||...  .|   .| ||  |.  
QNKFCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVA

EMFIANPIFAGQNE
| |   ||| |  |
ELFLGLPIFPGNSE
Kinase 86278.m00103.AA PRP4 44-283 32 3e-43 149.98 In-house 1-240 (320) Show / Hide 
Range on Protein: 44-283
Range on HMM: 1-240/320
Sequence Identity: 32% (80 aa)

FTILSPLGNGQFGNVFQVLCM-SADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEK-IAAEDRKYIITMIMAFEYHNHVCIVSELLSVDLYQVLK-
. . .. | | |.||  . |   .   . |  | ||  .    ..    |.|| ... ..    .|.. .. |   |....| |.| | .|  | .||| 
YRVYGYCGQGVFSNV--CRCRDQTRGNEMV--AIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKK

YRNFKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVNGNNAIKLIDFGSA-KTEGNFSDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVAI
|   .||..  ||   .||.  |  ||| .|.| |||| ||.    .| .|..||||| . . |    | .||.|||||...  |||| .|.|||.|   
YGKDVGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLY

EMFIANPIFAGQNELYLLQLISQYVSQIPISMIRSSPRRKDFFN
|..    .| |.     | |.  |   .|  ||| .  .  .|.
ELYTGKIMFPGKTNNHMLKLFMDYKGKMPNKMIRKGQFKDNHFD
Kinase 86278.m00103.AA Pkinase 44-260 25 2e-36 129.89 Pfam 1-230 (293) Show / Hide 
Range on Protein: 44-260
Range on HMM: 1-230/293
Sequence Identity: 25% (62 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANH-----EIEIHRRIQEKIAAEDRKYIITMIMAFEYHNHVCIVSELLSV-----
..|....| | || |   .|.  . .   ..|.|| | .    ..  .     ||.|..|..        ..|.... .||...|...| |..       
YHIGRKIGSGSFGCV--YKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVM

DLYQVLK---YRNFKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVNGNNA---IKLIDFGSA----KTEGNFSDFYFQSRYYRAPEVVL-N
||. ...   ...|  .|   ... ..|.|. |  . . |||| |.|||||. .| ..    .|..|||.|       .   . .  ...|.||||.. .
DLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

LPYDYKVDVWSVACVAIEMFIANPIFAGQ------NELYLLQLI
 .|..|||.||. |. .||.  .|.| |.      ........|
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI
Kinase 86278.m00103.AA CLK 44-181 29 6.2e-32 92.48 In-house 1-145 (350) Show / Hide 
Range on Protein: 44-181
Range on HMM: 1-145/350
Sequence Identity: 29% (44 aa)

FTILSPLGNGQFGNVFQVLCMSADMEA-PVVYAMKITKSQQHYQDQANHEIE-IHRRIQEKIAAEDRKY--IITMIMAFEY-HNHVCIVSELLSVDLYQV
..|.. || | || |...    .|..  .  .| || ..   | ..|  ||. | . |.||  ..  .   .. |.  |.| |.|.||| ||.   .| .
YEIVCTLGEGTFGKVVEC----WDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDF

LKYRN------FKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENI
.|  |      .... |. .|.. .||.. .  | .....| | |||||
MKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENI
Kinase 86278.m00103.AA STE 44-268 17 1.1e-30 105.65 In-house 1-301 (359) Show / Hide 
Range on Protein: 44-268
Range on HMM: 1-301/359
Sequence Identity: 17% (55 aa)

FTILSPLGNGQFGNVFQVLCMS---ADMEAPVV---------YAMKITK--SQQHYQDQ-------ANHEIEIHRRIQEKI-AAEDRK----YIITMIMA
..... .|.| || |.. ...     . .   |         .|.|. .  ... .. .        |  .|.. .|.. |    . .    .|.. . .
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC

FEYH-------NHVCIVSELLSV-DLYQVLKYRNFKGLSI------------SLVRNLLKQLLQD-LVVLKKIGIIHGDIKPENIMSVNGNNAIKLIDFG
...        ....|. |...   | ...| .  .| .             |...  ..|.|.  |  | . .||| |||| ||.       .||.|||
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFG

SAK-------------------TEGNFSDFYFQSRYYRAPEVVLN------LPYDYKVDVWSVACVAIEMFIANPIFAGQNELYLLQLISQYV-------
 ..                   | .  ..    .  . ||||...       .||.|.|.||. |..|||   .| ..  . .. . .| .         
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

------SQIP
       ..|
QLCIVNGPPP
Kinase 86278.m00103.AA Ciliate-E2 44-234 21 6.1e-30 99.96 In-house 1-282 (365) Show / Hide 
Range on Protein: 44-234
Range on HMM: 1-282/365
Sequence Identity: 21% (63 aa)

FTILSPLGNGQFG-----NVFQVLCMSA---------------DMEAPVVYAMKITKSQQHYQDQANHEI-EIH---RRIQEKIAAEDR--KYIITMIMA
. ..  .|.|.||     .| .| ...|                  .  ..   . |.|  .. | .|.. ||.   ..|.||   |    ..|| |. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--YHNHVCIVSELLSV-DLYQVLKYRNFKG---------LSISLVRNLLKQLLQ---------------DLVVLKKIG-IIHGDIKPENIMSVNGNNA
|.    |.. .| |...  ||.. .| .. |          ...  .... ||.||                |  |.. . ||| |||||||.       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

IKLIDFGSAKTEGNFSD---------FYFQSR--------------------------YYRAPEVVLNLP---------YDYKVDVWSV
||.|||| .|   ....          | . .                          .| |||.. . .         ||||.|.||.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL
Kinase 86278.m00103.AA CLK 187-288 28 4.3e-17 47.1 In-house 183-291 (350) Show / Hide 
Range on Protein: 187-288
Range on HMM: 183-291/350
Sequence Identity: 28% (31 aa)

NNAIKLIDFGSAK---TEGNFSDFYFQSRYYRAPEVVLNLPYDYKVDVWSVACVAIEMFIANPIFAGQNELYLLQLISQYVS-QIPISMIRSSP---RRK
|  |..||||||     .   .    ..| ||||||.| |.. .. ||||..|. .|  .    | . ...  |...      .|| .||...      .
NTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQ

DFFNHDNTL
 .|.|. ..
KYFYHNRLD
Kinase 86278.m00103.AA Ciliate-E2 346-370 43 8.4e-08 22.84 In-house 336-365 (365) Show / Hide 
Range on Protein: 346-370
Range on HMM: 336-365/365
Sequence Identity: 43% (13 aa)

LIQK----MLIIDPKLRPT-PEKCLEDPFF
||.|    ||  ||. |.| .|..|. |.|
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86278.m00103.AA CLK 346-370 52 7.2e-07 15.85 In-house 326-350 (350) Show / Hide 
Range on Protein: 346-370
Range on HMM: 326-350/350
Sequence Identity: 52% (13 aa)

LIQKMLIIDPKLRPTPEKCLEDPFF
||.|||..||  |.|    |  |||
LIRKMLEYDPSKRITCKDALQHPFF
Kinase 86278.m00103.AA STE 341-370 37 3e-06 17.98 In-house 328-359 (359) Show / Hide 
Range on Protein: 341-370
Range on HMM: 328-359/359
Sequence Identity: 37% (12 aa)

EHFLKLIQKMLIIDPKLRPTPEKCLE--DPFF
..|   |.| |..||. |||... |.   ||.
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86278.m00103.AA Pkinase 343-370 42 3e-06 23.25 Pfam 266-293 (293) Show / Hide 
Range on Protein: 343-370
Range on HMM: 266-293/293
Sequence Identity: 42% (12 aa)

FLKLIQKMLIIDPKLRPTPEKCLEDPFF
....| ..|  ||| |||.| .|..|.|
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86278.m00103.AA PRP4 346-370 44 1.4e-05 16.53 In-house 296-320 (320) Show / Hide 
Range on Protein: 346-370
Range on HMM: 296-320/320
Sequence Identity: 44% (11 aa)

LIQKMLIIDPKLRPTPEKCLEDPFF
|. |.|. ||| | |..  |. ||.
LLDKCLMLDPKKRITCNEALKHPFI
Kinase 86278.m00103.AA TyrKc 44-368 15 1.5e-05 -132.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-368
Range on HMM: 1-280/280
Sequence Identity: 15% (57 aa)

FTILSPLGNGQFGNVFQVLCMSADMEAPVVYAMKITKSQQHYQDQANHEIEIHRRIQEKIAAE--DRKYIITMIMAFEYH-------NHVCIVSELLSV-
 | .  ||.|.|| |..           .  | |  |.          . ...| ..        . . |. .. .   .         ..|| |. .  
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--------REDFMREAR-IMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

DLYQVL-KYRNFKGLSISLVRNLLKQLLQDLVVLKKIGIIHGDIKPENIMSVNGNNAIKLIDFGSAKTEGNF------SDFYF-----QSR-----YYRA
|| . | |.|.   |. .   .   |  .    | . ..|| |.   |.. |. |. .|  ||| ..  ..       .| |      ...        |
DLKDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL-VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEVVLNLPYDYKVDVWSVACVAIEMF--IANPIFA-----GQNELYLLQLISQYVSQIPIS---MIRSSPRRKDFFNHDNTLKTLNQYCYENGIQVPQFQ
||.     .  | ||||   .  |.|   . |          |.  . .. . |   .| .   |                                   
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------

PYLIYNTISELIMKYPIARANKQGDFLQKEMTRREHFLKLIQKMLIIDPKLRPTPEKCLEDP
                         |     .  .   .....    ||. ||| . . |. 
-------------------------F----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 86278.m00103.AA YAK 287-370 21 0.00036 9.63 In-house 265-347 (347) Show / Hide 
Range on Protein: 287-370
Range on HMM: 265-347/347
Sequence Identity: 21% (18 aa)

TLKTLNQYCYENGIQVPQFQPYLIYNTISELIMKYPIARANKQGDFLQKEMTRREHFLKLIQKMLIIDPKLRPTPEKCLEDPFF
..||   |  . .||      |  | .  ...  .   .  .  |   |.  .|. |. .|  .|  .|. | .|    . || 
IFKTKQDYQIDEKIQLKESKTYFQYKCLNDIKNYMYFKQFMRNQD-DTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI